Glycolysis and glutaminolysis cooperatively control T cell function by limiting metabolite supply to N-glycosylation

Golgi self-correction generates bioequivalent glycans to preserve cellular homeostasis

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Metabolic Reprogramming by Hexosamine Biosynthetic and Golgi N-Glycan Branching Pathways

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Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses

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Glutamine-dependent α-ketoglutarate production regulates the balance between T helper 1 cell and regulatory T cell generation

(2015) Dorota Klysz et al.   Science Signaling

Glutamine-dependent α-ketoglutarate production regulates the balance between T helper 1 cell and regulatory T cell generation

(2015) Dorota Klysz et al.   Science Signaling

Mannose metabolism: More than meets the eye

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2-Deoxy-D-glucose targeting of glucose metabolism in cancer cells as a potential therapy

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Targeting Lactate Dehydrogenase-A Inhibits Tumorigenesis and Tumor Progression in Mouse Models of Lung Cancer and Impacts Tumor-Initiating Cells

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N-glycosylation bidirectionally extends the boundaries of thymocyte positive selection by decoupling Lck from Ca2+ signaling

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O-GlcNAc Transferase Integrates Metabolic Pathways to Regulate the Stability of c-MYC in Human Prostate Cancer Cells

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Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis

(2013) Chih-Hao Chang et al.   CELL

Rapid effector function of memory CD8+ T cells requires an immediate-early glycolytic switch

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Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism

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Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation

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N-Acetylglucosamine Inhibits T-helper 1 (Th1)/T-helper 17 (Th17) Cell Responses and Treats Experimental Autoimmune Encephalomyelitis

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HIF1α–dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Tregcells

(2011) Lewis Z. Shi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cutting Edge: Distinct Glycolytic and Lipid Oxidative Metabolic Programs Are Essential for Effector and Regulatory CD4+ T Cell Subsets

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Genetics and the environment converge to dysregulate N-glycosylation in multiple sclerosis

(2011) Haik Mkhikian et al.   Nature Communications

The hexosamine biosynthetic pathway couples growth factor-induced glutamine uptake to glucose metabolism

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Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression

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Metabolism, Cell Surface Organization, and Disease

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T Cell Receptor Signaling Co-regulates Multiple Golgi Genes to EnhanceN-Glycan Branching

(2009) Hung-Lin Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

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