PEGylated Curcumin Derivative Attenuates Hepatic Steatosis via CREB/PPAR-γ/CD36 Pathway

Modulation of cAMP levels by high-fat diet and curcumin and regulatory effects on CD36/FAT scavenger receptor/fatty acids transporter gene expression

(2016) Jean-Marc Zingg et al.   BIOFACTORS

Emerging Therapies for Nonalcoholic Fatty Liver Disease

(2016) Bilal Hameed et al.   Clinics in Liver Disease

Curcumin Lowers Serum Lipids and Uric Acid in Subjects With Nonalcoholic Fatty Liver Disease

(2016) Yunes Panahi et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Hepatocyte-specific, PPARγ-regulated mechanisms to promote steatosis in adult mice

(2016) Abigail Wolf Greenstein et al.   JOURNAL OF ENDOCRINOLOGY

Non-alcoholic steatohepatitis: emerging molecular targets and therapeutic strategies

(2016) Giovanni Musso et al.   NATURE REVIEWS DRUG DISCOVERY

Dietary sweet cherry anthocyanins attenuates diet-induced hepatic steatosis by improving hepatic lipid metabolism in mice

(2016) Haizhao Song et al.   NUTRITION

Treatment of Non-alcoholic Fatty Liver Disease with Curcumin: A Randomized Placebo-controlled Trial

(2016) Sepideh Rahmani et al.   PHYTOTHERAPY RESEARCH

Curcumin rescues high fat diet-induced obesity and insulin sensitivity in mice through regulating SREBP pathway

(2016) Lili Ding et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Herbal medicines and nonalcoholic fatty liver disease

(2016) Hong Yao et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Natural antioxidants for non-alcoholic fatty liver disease: molecular targets and clinical perspectives

(2015) Federico Salomone et al.   LIVER INTERNATIONAL

Curcumin, a component of golden spice: From bedside to bench and back

(2014) Sahdeo Prasad et al.   BIOTECHNOLOGY ADVANCES

Current Status and Prospects of Polyethyleneglycol-Modified Medicines

(2013) Hiroshi Ishihara   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Curcumin prevents liver fat accumulation and serum fetuin-A increase in rats fed a high-fat diet

(2013) Yildiz Öner-İyidoğan et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

PPARγ signaling and metabolism: the good, the bad and the future

(2013) Maryam Ahmadian et al.   NATURE MEDICINE

NAFLD in Asia—as common and important as in the West

(2013) Geoffrey C. Farrell et al.   Nature Reviews Gastroenterology & Hepatology

Synthetic FXR Agonist GW4064 Prevents Diet-Induced Hepatic Steatosis and Insulin Resistance

(2013) Yongjie Ma et al.   PHARMACEUTICAL RESEARCH

Why it is necessary to translate curcumin into clinical practice for the prevention and treatment of metabolic syndrome?

(2012) Amirhossein Sahebkar   BIOFACTORS

Impact of current treatments on liver disease, glucose metabolism and cardiovascular risk in non-alcoholic fatty liver disease (NAFLD): a systematic review and meta-analysis of randomised trials

(2012) G. Musso et al.   DIABETOLOGIA

Curcumin Prevents High Fat Diet Induced Insulin Resistance and Obesity via Attenuating Lipogenesis in Liver and Inflammatory Pathway in Adipocytes

(2012) Weijuan Shao et al.   PLoS One

Systematic review: the epidemiology and natural history of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in adults

(2011) G. Vernon et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Design, synthesis and evaluation of novel PEGylated curcumin analogs as potent Nrf2 activators in human bronchial epithelial cells

(2011) Mukesh K. Pandey et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Role for PPARγ in obesity-induced hepatic steatosis as determined by hepatocyte- and macrophage-specific conditional knockouts

(2011) Eva Morán-Salvador et al.   FASEB JOURNAL

Hepatic fatty acid translocase CD36 upregulation is associated with insulin resistance, hyperinsulinaemia and increased steatosis in non-alcoholic steatohepatitis and chronic hepatitis C

(2011) M. E. Miquilena-Colina et al.   GUT

Effects of Different Carboxylic Ester Spacers on Chemical Stability, Release Characteristics, and Anticancer Activity of Mono-PEGylated Curcumin Conjugates

(2011) Wisut Wichitnithad et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Human Fatty Liver Disease: Old Questions and New Insights

(2011) J. C. Cohen et al.   SCIENCE

A critical analysis of three quantitative methods of assessment of hepatic steatosis in liver biopsies

(2011) Mariana Catta-Preta et al.   VIRCHOWS ARCHIV

A Novel Role for the Dioxin Receptor in Fatty Acid Metabolism and Hepatic Steatosis

(2010) Jung Hoon Lee et al.   GASTROENTEROLOGY

Amphiphilic curcumin conjugate-forming nanoparticles as anticancer prodrug and drug carriers:in vitroandin vivoeffects

(2010) Huadong Tang et al.   Nanomedicine

Definition and natural history of metabolic steatosis: clinical aspects of NAFLD, NASH and cirrhosis

(2009) L. Serfaty et al.   DIABETES & METABOLISM

Gene expression in human NAFLD

(2008) Dario Greco et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Beneficial effects of curcumin on hyperlipidemia and insulin resistance in high-fat–fed hamsters

(2008) Eun-Mi Jang et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

The Tangle of Nuclear Receptors that Controls Xenobiotic Metabolism and Transport: Crosstalk and Consequences

(2007) Jean-Marc Pascussi et al.   Annual Review of Pharmacology and Toxicology

Hepatic Fatty Acid Transporter Cd36 Is a Common Target of LXR, PXR, and PPARγ in Promoting Steatosis

(2007) Jie Zhou et al.   GASTROENTEROLOGY