Human Fatty Liver Disease: Old Questions and New Insights

Lack of an association between an apolipoprotein C3 genetic variant and the liver fat content in patients with type 2 diabetes

(2011) Jean Michel Petit et al.   HEPATOLOGY

Genetic determinants of hepatic steatosis in man

(2011) Amanda J. Hooper et al.   JOURNAL OF LIPID RESEARCH

Genome-Wide Association Analysis Identifies Variants Associated with Nonalcoholic Fatty Liver Disease That Have Distinct Effects on Metabolic Traits

(2011) Elizabeth K. Speliotes et al.   PLoS Genetics

Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease

(2010) Gökhan S. Hotamisligil   CELL

Unravelling the pathogenesis of fatty liver disease: patatin-like phospholipase domain-containing 3 protein

(2010) Stefano Romeo et al.   CURRENT OPINION IN LIPIDOLOGY

The Role of Cytokines in Non-Alcoholic Fatty Liver Disease

(2010) Herbert Tilg   DIGESTIVE DISEASES

Nonalcoholic fatty liver disease and hepatocellular carcinoma: A weighty connection

(2010) Brad Q. Starley et al.   HEPATOLOGY

Dissociation between APOC3 variants, hepatic triglyceride content and insulin resistance

(2010) Julia Kozlitina et al.   HEPATOLOGY

Fitness versus fatness: Moving beyond weight loss in nonalcoholic fatty liver disease

(2010) Nathan A. Johnson et al.   HEPATOLOGY

Patatin-like phospholipase domain-containing 3/adiponutrin deficiency in mice is not associated with fatty liver disease

(2010) Weiqin Chen et al.   HEPATOLOGY

Pnpla3/Adiponutrin deficiency in mice does not contribute to fatty liver disease or metabolic syndrome

(2010) Mahesh K. Basantani et al.   JOURNAL OF LIPID RESEARCH

CGI-58 knockdown in mice causes hepatic steatosis but prevents diet-induced obesity and glucose intolerance

(2010) J. Mark Brown et al.   JOURNAL OF LIPID RESEARCH

Animal models of nonalcoholic fatty liver disease

(2010) Lionel Hebbard et al.   Nature Reviews Gastroenterology & Hepatology

Apolipoprotein C3 Gene Variants in Nonalcoholic Fatty Liver Disease

(2010) Kitt Falk Petersen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pioglitazone, Vitamin E, or Placebo for Nonalcoholic Steatohepatitis

(2010) Arun J. Sanyal et al.   NEW ENGLAND JOURNAL OF MEDICINE

Metabolic Effects of Fructose and the Worldwide Increase in Obesity

(2010) Luc Tappy et al.   PHYSIOLOGICAL REVIEWS

A feed-forward loop amplifies nutritional regulation of PNPLA3

(2010) Yongcheng Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis

(2010) Shijie Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Novel Insights into the Pathophysiology of Nonalcoholic Fatty Liver Disease

(2010) Ariel Feldstein   SEMINARS IN LIVER DISEASE

Epidemiology and Natural History of Non-Alcoholic Steatohepatitis

(2009) Curtis K. Argo et al.   Clinics in Liver Disease

Heritability of Nonalcoholic Fatty Liver Disease

(2009) Jeffrey B. Schwimmer et al.   GASTROENTEROLOGY

A Sequence Variation (I148M) in PNPLA3 Associated with Nonalcoholic Fatty Liver Disease Disrupts Triglyceride Hydrolysis

(2009) Shaoqing He et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Systematic review of risk factors for fibrosis progression in non-alcoholic steatohepatitis

(2009) Curtis K. Argo et al.   JOURNAL OF HEPATOLOGY

A nonsynonymous gene variant in the adiponutrin gene is associated with nonalcoholic fatty liver disease severity

(2009) Silvia Sookoian et al.   JOURNAL OF LIPID RESEARCH

Recurrent disease following liver transplantation for nonalcoholic steatohepatitis cirrhosis

(2009) Shahid M. Malik et al.   LIVER TRANSPLANTATION

Variant in PNPLA3 is associated with alcoholic liver disease

(2009) Chao Tian et al.   NATURE GENETICS

Lipotoxicity in nonalcoholic fatty liver disease: not all lipids are created equal

(2009) Naim Alkhouri et al.   Expert Review of Gastroenterology & Hepatology

Population-Based Genome-wide Association Studies Reveal Six Loci Influencing Plasma Levels of Liver Enzymes

(2008) Xin Yuan et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Selective versus Total Insulin Resistance: A Pathogenic Paradox

(2008) Michael S. Brown et al.   Cell Metabolism

Effect of Bariatric Surgery on Nonalcoholic Fatty Liver Disease: Systematic Review and Meta-Analysis

(2008) Rajasekhara R. Mummadi et al.   Clinical Gastroenterology and Hepatology

Risk of severe liver disease in nonalcoholic fatty liver disease with normal aminotransferase levels: A role for insulin resistance and diabetes

(2008) Anna Ludovica Fracanzani et al.   HEPATOLOGY

Citrin deficiency as a cause of chronic liver disorder mimicking non-alcoholic fatty liver disease

(2008) Michiharu Komatsu et al.   JOURNAL OF HEPATOLOGY

Hepatic triacylglycerol accumulation and insulin resistance

(2008) Cynthia A. Nagle et al.   JOURNAL OF LIPID RESEARCH

Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease

(2008) Stefano Romeo et al.   NATURE GENETICS

Increased de novo Lipogenesis and Delayed Conversion of Large VLDL into Intermediate Density Lipoprotein Particles Contribute to Hyperlipidemia in Glycogen Storage Disease Type 1a

(2008) Robert H J Bandsma et al.   PEDIATRIC RESEARCH