Continuous flow-ultrasonic synergy in click reactions for the synthesis of novel 1,2,3-triazolyl appended 4,5-unsaturated l-ascorbic acid derivatives

Carbohydrate CuAAC click chemistry for therapy and diagnosis

(2016) Xiao-Peng He et al.   CARBOHYDRATE RESEARCH

Synthesis, in vitro anticancer and antibacterial activities and in silico studies of new 4-substituted 1,2,3-triazole–coumarin hybrids

(2016) Tatjana Gazivoda Kraljević et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

1,2,3-Triazole pharmacophore-based benzofused nitrogen/sulfur heterocycles with potential anti-Moraxella catarrhalis activity

(2015) Silvija Maračić et al.   BIOORGANIC & MEDICINAL CHEMISTRY

The utilization of copper flow reactors in organic synthesis

(2015) Jennifer Bao et al.   CHEMICAL COMMUNICATIONS

Recent Trends in 1,2,3-Triazolo-Nucleosides as Promising Anti-Infective and Anticancer Agents

(2015) Silvana Raic-Malic et al.   CURRENT MEDICINAL CHEMISTRY

A high-power ultrasonic microreactor and its application in gas–liquid mass transfer intensification

(2015) Zhengya Dong et al.   LAB ON A CHIP

Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH

(2015) J. Yun et al.   SCIENCE

Flow chemistry as a versatile tool for the synthesis of triazoles

(2015) Sándor B. Ötvös et al.   Catalysis Science & Technology

Accessing New Chemical Entities through Microfluidic Systems

(2014) Tiago Rodrigues et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of novel 1,2,3-triazole substituted-N-alkyl/aryl nitrone derivatives, their anti-inflammatory and anticancer activity

(2014) P. Sambasiva Rao et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and anticancer activity of γ-(triazolyl ethylidene)butenolides and polyfunctional pyrrolinones

(2014) N. Devender et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

1,2,3-Triazole-containing derivatives of rupestonic acid: Click-chemical synthesis and antiviral activities against influenza viruses

(2014) Yao-Wu He et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Flow approaches towards sustainability

(2014) Luigi Vaccaro et al.   GREEN CHEMISTRY

Intravenous Vitamin C and Cancer

(2014) Heidi Fritz et al.   INTEGRATIVE CANCER THERAPIES

ADH-catalysed hexanol oxidation with fully integrated NADH regeneration performed in microreactors connected in series

(2014) Anita Šalić et al.   RSC Advances

Flow chemistry syntheses of natural products

(2013) Julio C. Pastre et al.   CHEMICAL SOCIETY REVIEWS

Alkyne-Azide Cycloadditions with Copper Powder in a High-Pressure Continuous-Flow Reactor: High-Temperature Conditions versus the Role of Additives

(2013) Sándor B. Ötvös et al.   Chemistry-An Asian Journal

Design, synthesis and antiproliferative activity studies of novel 1,2,3-triazole–dithiocarbamate–urea hybrids

(2013) Ying-Chao Duan et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Effects of Vitamin C on health: a review of evidence

(2013) Roberto Bei   Frontiers in Bioscience-Landmark

Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells

(2013) Kathryn Blaschke et al.   NATURE

Recent advances in the Cu(i)-catalyzed azide–alkyne cycloaddition: focus on functionally substituted azides and alkynes

(2013) Nadezhda V. Sokolova et al.   RSC Advances

Flow Chemistry - A Key Enabling Technology for (Multistep) Organic Synthesis

(2012) Jens Wegner et al.   ADVANCED SYNTHESIS & CATALYSIS

Merging microfluidics and sonochemistry: towards greener and more efficient micro-sono-reactors

(2012) David Fernandez Rivas et al.   CHEMICAL COMMUNICATIONS

Ultrasound and Microstructures-A Promising Combination?

(2012) S. Hübner et al.   ChemSusChem

Synthesis and in vitro evaluation of potential anticancer activity of mono- and bis-1,2,3-triazole derivatives of bis-alkynes

(2012) Hichem Elamari et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

The impact of click chemistry in medicinal chemistry

(2012) Jingli Hou et al.   Expert Opinion on Drug Discovery

Design, Synthesis, and in Vitro Biological Evaluation of 1H-1,2,3-Triazole-4-carboxamide Derivatives as New Anti-influenza A Agents Targeting Virus Nucleoprotein

(2012) Huimin Cheng et al.   JOURNAL OF MEDICINAL CHEMISTRY

Continuous Flow Synthesis. A Pharma Perspective

(2012) Laia Malet-Sanz et al.   JOURNAL OF MEDICINAL CHEMISTRY

Sonoluminescence and sonochemiluminescence from a microreactor

(2012) David Fernandez Rivas et al.   ULTRASONICS SONOCHEMISTRY

Dissolved gas and ultrasonic cavitation – A review

(2012) Joost Rooze et al.   ULTRASONICS SONOCHEMISTRY

Pharmacological ascorbate induces cytotoxicity in prostate cancer cells through ATP depletion and induction of autophagy

(2011) Ping Chen et al.   ANTI-CANCER DRUGS

Recent advances in micro reaction technology

(2011) Charlotte Wiles et al.   CHEMICAL COMMUNICATIONS

“Clicking” on/with polymers: a rapidly expanding field for the straightforward preparation of novel macromolecular architectures

(2011) Kristian Kempe et al.   CHEMICAL SOCIETY REVIEWS

Reactions under the Click Chemistry Philosophy Employed in Supramolecular and Mechanostereochemical Systems

(2011) Albert C. Fahrenbach et al.   Chemistry-An Asian Journal

Applications of 2-arylhydrazononitriles in synthesis: Preparation of new indole containing 1,2,3-triazole, pyrazole and pyrazolo[1,5-a]pyrimidine derivatives and evaluation of their antimicrobial activities

(2011) Haider Behbehani et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Experimental Investigation on the Mechanism of Chelation-Assisted, Copper(II) Acetate-Accelerated Azide–Alkyne Cycloaddition

(2011) Gui-Chao Kuang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Strained Cyclophane Macrocycles: Impact of Progressive Ring Size Reduction on Synthesis and Structure

(2011) Andrew R. Bogdan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of 5-Iodo-1,2,3-triazole-Containing Macrocycles Using Copper Flow Reactor Technology

(2011) Andrew R. Bogdan et al.   ORGANIC LETTERS

Sonochemistry and sonoluminescence in microfluidics

(2011) Tandiono et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Click chemistry generates privileged CH hydrogen-bonding triazoles: the latest addition to anion supramolecular chemistry

(2010) Yuran Hua et al.   CHEMICAL SOCIETY REVIEWS

Click chemistry with DNA

(2010) Afaf H. El-Sagheer et al.   CHEMICAL SOCIETY REVIEWS

Efficient Access to New Chemical Space Through Flow-Construction of Druglike Macrocycles Through Copper-Surface-Catalyzed Azide-Alkyne Cycloaddition Reactions

(2010) Andrew R. Bogdan et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis of novel sulfanilamide-derived 1,2,3-triazoles and their evaluation for antibacterial and antifungal activities

(2010) Xian-Long Wang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Creation of cavitation activity in a microfluidic device through acoustically driven capillary waves

(2010) Tandiono et al.   LAB ON A CHIP

Continuous Flow Coupling and Decarboxylation Reactions Promoted by Copper Tubing

(2010) Yun Zhang et al.   ORGANIC LETTERS

Exploration of click reaction for the synthesis of modified nucleosides as chitin synthase inhibitors

(2009) Preeti M. Chaudhary et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Applications of Orthogonal “Click” Chemistries in the Synthesis of Functional Soft Materials

(2009) Rhiannon K. Iha et al.   CHEMICAL REVIEWS

Click chemistry under non-classical reaction conditions

(2009) C. Oliver Kappe et al.   CHEMICAL SOCIETY REVIEWS

L-Ascorbic Acid in Organic Synthesis: An Overview

(2009) Rama Tripathi et al.   CURRENT ORGANIC CHEMISTRY

Continuous-flow organic synthesis: a tool for the modern medicinal chemist

(2009) Charlotte Wiles et al.   Future Medicinal Chemistry

Microchemical systems for continuous-flow synthesis

(2009) Ryan L. Hartman et al.   LAB ON A CHIP

Synthesis and biological evaluation of bile acid dimers linked with 1,2,3-triazole and bis-β-lactam

(2008) Namdev S. Vatmurge et al.   ORGANIC & BIOMOLECULAR CHEMISTRY