Continuous-flow organic synthesis: a tool for the modern medicinal chemist

CONCENTRATES

(2010)   CHEMICAL & ENGINEERING NEWS

Multistep Synthesis Using Modular Flow Reactors: Bestmann-Ohira Reagent for the Formation of Alkynes and Triazoles

(2009) Ian R. Baxendale et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

5-(Pyrrolidin-2-yl)tetrazole-Catalyzed Aldol and Mannich Reactions: Acceleration and Lower Catalyst Loading in a Continuous-Flow Reactor

(2009) Arjan Odedra et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Functionalized Inorganic Monolithic Microreactors for High Productivity in Fine Chemicals Catalytic Synthesis

(2009) Abdelkrim El Kadib et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of unsymmetrically substituted biaryls via sequential lithiation of dibromobiaryls using integrated microflow systems

(2009) Aiichiro Nagaki et al.   Beilstein Journal of Organic Chemistry

Oxidative cyclization of alkenols with Oxone using a miniflow reactor

(2009) Yoichi M A Yamada et al.   Beilstein Journal of Organic Chemistry

The development and evaluation of a continuous flow process for the lipase-mediated oxidation of alkenes

(2009) Charlotte Wiles et al.   Beilstein Journal of Organic Chemistry

Efficient Continuous Flow Synthesis of Hydroxamic Acids and Suberoylanilide Hydroxamic Acid Preparation

(2009) Elena Riva et al.   JOURNAL OF ORGANIC CHEMISTRY

Microreactors for radiopharmaceutical synthesis

(2009) Arkadij M. Elizarov   LAB ON A CHIP

Distillation in microchemical systems using capillary forces and segmented flow

(2009) Ryan L. Hartman et al.   LAB ON A CHIP

A three-phase microfluidic chip for rapid sample clean-up of alkaloids from plant extracts

(2009) Kishore K. R. Tetala et al.   LAB ON A CHIP

Adaptation of an Exothermic and Acylazide-Involving Synthesis Sequence to Microreactor Technology

(2009) Luigi Rumi et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Improved Synthesis of 1-(Azidomethyl)-3,5-bis-(trifluoromethyl)benzene: Development of Batch and Microflow Azide Processes

(2009) Michael E. Kopach et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Trimethylaluminium mediated amide bond formation in a continuous flow microreactor as key to the synthesis of rimonabant and efaproxiral

(2008) Tomas Gustafsson et al.   CHEMICAL COMMUNICATIONS

Fluorination reactions in microreactors

(2008) Tomas Gustafsson et al.   CHEMICAL COMMUNICATIONS

Continuous Flow Reactors, a Tool for the Modern Synthetic Chemist

(2008) Charlotte Wiles et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Evaluation of the Heterogeneously Catalyzed Strecker Reaction Conducted Under Continuous Flow

(2008) Charlotte Wiles et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Circulation microchannel for liquid–liquid microextraction

(2008) Yoshikuni Kikutani et al.   MICROCHIMICA ACTA

Azide monoliths as convenient flow reactors for efficient Curtius rearrangement reactions

(2008) Marcus Baumann et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Investigation of the Moffatt−Swern Oxidation in a Continuous Flow Microreactor System

(2008) Jacobus J. M. van der Linden et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

An Integrated Microreactor for the Multicomponent Synthesis of α-Aminonitriles1

(2008) Charlotte Wiles et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Dibal-H Reduction of Methyl Butyrate into Butyraldehyde using Microreactors

(2008) Laurent Ducry et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Transition Metal-Catalyzed Carbon−Carbon Bond Formation Suzuki, Heck, and Sonogashira Reactions Using Microwave and Microtechnology

(2008) Brajendra K. Singh et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Elemental Fluorine. Part 21.1 Direct Fluorination of Benzaldehyde Derivatives

(2008) Richard D. Chambers et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Epoxidation of alkenes using HOF·MeCN by a continuous flow process

(2008) Christopher B. McPake et al.   TETRAHEDRON LETTERS

Copper-mediated N- and O-arylations with arylboronic acids in a continuous flow microreactor: a new avenue for efficient scalability

(2008) Brajendra K. Singh et al.   TETRAHEDRON LETTERS

Enantiomer selective acylation of racemic alcohols by lipases in continuous-flow bioreactors

(2008) Csaba Csajági et al.   TETRAHEDRON-ASYMMETRY

Diels–Alder cycloadditions by microwave-assisted, continuous flow organic synthesis (MACOS): the role of metal films in the flow tube

(2007) Gjergji Shore et al.   CHEMICAL COMMUNICATIONS

Click chemistry reactions in medicinal chemistry: Applications of the 1,3-dipolar cycloaddition between azides and alkynes

(2007) Gian Cesare Tron et al.   MEDICINAL RESEARCH REVIEWS