GM1 Ganglioside: Past Studies and Future Potential

Labeled chemical biology tools for investigating sphingolipid metabolism, trafficking and interaction with lipids and proteins

(2014) Günter Schwarzmann et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Simplifying complexity: genetically resculpting glycosphingolipid synthesis pathways in mice to reveal function

(2014) Maria Laura Allende et al.   GLYCOCONJUGATE JOURNAL

GM1 ganglioside enhances Ret signaling in striatum

(2014) Erin N. Newburn et al.   JOURNAL OF NEUROCHEMISTRY

Monossialogangliosídeo transdérmico com laser no tratamento de lesão medular espinal de ratos

(2013) Fabiano Inácio de Souza et al.   Acta Ortopedica Brasileira

Sphingolipids and Brain Resident Macrophages in Neuroinflammation: An Emerging Aspect of Nervous System Pathology

(2013) Emma Assi et al.   Clinical & Developmental Immunology

Ganglioside GM1-mediated Transcytosis of Cholera Toxin Bypasses the Retrograde Pathway and Depends on the Structure of the Ceramide Domain

(2013) David E. Saslowsky et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prion Protein-mediated Toxicity of Amyloid-β Oligomers Requires Lipid Rafts and the Transmembrane LRP1

(2013) Jo V. Rushworth et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipid Rafts in Neurodegeneration and Neuroprotection

(2013) Sandro Sonnino et al.   MOLECULAR NEUROBIOLOGY

Raft-like membranes from the trans-Golgi network and endosomal compartments

(2013) Mark G Waugh   Nature Protocols

Alterations on Na+,K+-ATPase and Acetylcholinesterase Activities Induced by Amyloid-β Peptide in Rat Brain and GM1 Ganglioside Neuroprotective Action

(2013) Fernando Kreutz et al.   NEUROCHEMICAL RESEARCH

GLTP Mediated Non-Vesicular GM1 Transport between Native Membranes

(2013) Ines Lauria et al.   PLoS One

Binding, Conformational Transition and Dimerization of Amyloid-β Peptide on GM1-Containing Ternary Membrane: Insights from Molecular Dynamics Simulation

(2013) Moutusi Manna et al.   PLoS One

Ganglioside-monosialic acid (GM1) prevents oxaliplatin-induced peripheral neurotoxicity in patients with gastrointestinal tumors

(2013) Yanyun Zhu et al.   World Journal of Surgical Oncology

Cholesterol accelerates the binding of Alzheimer's β-amyloid peptide to ganglioside GM1 through a universal hydrogen-bond-dependent sterol tuning of glycolipid conformation

(2013) Jacques Fantini et al.   Frontiers in Physiology

Biochemical Identification of a Linear Cholesterol-Binding Domain within Alzheimer’s β Amyloid Peptide

(2012) Coralie Di Scala et al.   ACS Chemical Neuroscience

Is the Amyloid Hypothesis of Alzheimer's disease therapeutically relevant?

(2012) Andrew F. Teich et al.   BIOCHEMICAL JOURNAL

Lipid Sorting by Ceramide Structure from Plasma Membrane to ER for the Cholera Toxin Receptor Ganglioside GM1

(2012) Daniel J.-F. Chinnapen et al.   DEVELOPMENTAL CELL

Dysregulation of cholesterol balance in the brain: contribution to neurodegenerative diseases

(2012) J. E. Vance   Disease Models & Mechanisms

A randomized, controlled, delayed start trial of GM1 ganglioside in treated Parkinson's disease patients

(2012) Jay S. Schneider et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Guillain^|^ndash;Barr^|^eacute; syndrome and anti-ganglioside antibodies: a clinician-scientist^|^rsquo;s journey

(2012) Nobuhiro YUKI   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

Glycoconjugates Play a Key Role in Campylobacter jejuni Infection: Interactions between Host and Pathogen

(2012) Christopher James Day et al.   Frontiers in Cellular and Infection Microbiology

Nuclear Sphingolipid Metabolism

(2011) Natasha C. Lucki et al.   Annual Review of Physiology

The fusogenic tilted peptide (67–78) of α-synuclein is a cholesterol binding domain

(2011) Jacques Fantini et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Gangliosides and the multiscale modulation of membrane structure

(2011) Laura Cantù et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Anti-GM1/GD1a complex antibodies in GBS sera specifically recognize the hybrid dimer GM1-GD1a

(2011) L. Mauri et al.   GLYCOBIOLOGY

Nanoscale structural response of ganglioside-containing aggregates to the interaction with sialidase

(2011) Elena Del Favero et al.   JOURNAL OF NEUROCHEMISTRY

Mice Lacking Major Brain Gangliosides Develop Parkinsonism

(2011) Gusheng Wu et al.   NEUROCHEMICAL RESEARCH

Direct binding of cholesterol to the amyloid precursor protein: An important interaction in lipid–Alzheimer's disease relationships?

(2010) Andrew J. Beel et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Exploring Membrane Dynamics by Fluorescence Nanoscopy

(2010) Christian Eggeling et al.   BIOPHYSICAL JOURNAL

Membrane Lipids, Selectively Diminished in Alzheimer Brains, Suggest Synapse Loss as a Primary Event in Early-Onset Form (Type I) and Demyelination in Late-Onset Form (Type II)

(2010) Lars Svennerholm et al.   JOURNAL OF NEUROCHEMISTRY

Anti-GM1 antibodies affect the integrity of lipid rafts

(2010) Akihiro Ueda et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Deregulated Sphingolipid Metabolism and Membrane Organization in Neurodegenerative Disorders

(2010) Marco Piccinini et al.   MOLECULAR NEUROBIOLOGY

Cholera Toxin: An Intracellular Journey into the Cytosol by Way of the Endoplasmic Reticulum

(2010) Naomi L. B. Wernick et al.   Toxins

Lipids and Membrane Lateral Organization

(2010) Sandro Sonnino et al.   Frontiers in Physiology

Differential endocytic trafficking of neuropathy-associated antibodies to GM1 ganglioside and cholera toxin in epithelial and neural cells

(2009) Ramiro Iglesias-Bartolomé et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Segregation of GM1 and GM3 clusters in the cell membrane depends on the intact actin cytoskeleton

(2009) Akikazu Fujita et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

High-Resolution Far-Field Fluorescence STED Microscopy Reveals Nanoscale Details of Molecular Membrane Dynamics

(2009) Christian Eggeling et al.   BIOPHYSICAL JOURNAL

Binding of laminin-1 to monosialoganglioside GM1 in lipid rafts is crucial for neurite outgrowth

(2009) N. Ichikawa et al.   JOURNAL OF CELL SCIENCE

GM1-Ganglioside Accumulation at the Mitochondria-Associated ER Membranes Links ER Stress to Ca2+-Dependent Mitochondrial Apoptosis

(2009) Renata Sano et al.   MOLECULAR CELL

Order of lipid phases in model and plasma membranes

(2009) H.-J. Kaiser et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Age-dependent high-density clustering of GM1 ganglioside at presynaptic neuritic terminals promotes amyloid β-protein fibrillogenesis

(2008) Naoki Yamamoto et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Up-and-down topological mode of amyloid β-peptide lying on hydrophilic/hydrophobic interface of ganglioside clusters

(2008) Maho Utsumi et al.   GLYCOCONJUGATE JOURNAL

Thematic Review Series: Sphingolipids.Role of ganglioside metabolism in the pathogenesis of Alzheimer's disease—a review,

(2008) Toshio Ariga et al.   JOURNAL OF LIPID RESEARCH

Accelerated release of exosome-associated GM1 ganglioside (GM1) by endocytic pathway abnormality: another putative pathway for GM1-induced amyloid fibril formation

(2008) Kohei Yuyama et al.   JOURNAL OF NEUROCHEMISTRY

Direct observation of the nanoscale dynamics of membrane lipids in a living cell

(2008) Christian Eggeling et al.   NATURE

Microscopy and its focal switch

(2008) Stefan W Hell   NATURE METHODS

Plasma membranes are poised for activation of raft phase coalescence at physiological temperature

(2008) D. Lingwood et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA