Substoichiometric Levels of Cu2+Ions Accelerate the Kinetics of Fiber Formation and Promote Cell Toxicity of Amyloid-β from Alzheimer Disease

Trace Copper(II) or Zinc(II) Ions Drastically Modify the Aggregation Behavior of Amyloid-β1–42: An AFM Study

(2017) Massimo Innocenti et al.   JOURNAL OF ALZHEIMERS DISEASE

Control of Alzheimer's Amyloid Beta Toxicity by the High Molecular Weight Immunophilin FKBP52 and Copper Homeostasis in Drosophila

(2010) Reiko Sanokawa-Akakura et al.   PLoS One

Zinc ions promote Alzheimer A  aggregation via population shift of polymorphic states

(2010) Y. Miller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pulse EPR Spectroscopy Reveals the Coordination Sphere of Copper(II) Ions in the 1–16 Amyloid-β Peptide: A Key Role of the First Two N-Terminus Residues

(2009) Pierre Dorlet et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Second Cu(II)-Binding Site in a Proton-Rich Environment Interferes with the Aggregation of Amyloid-β(1−40) into Amyloid Fibrils

(2009) Sangmi Jun et al.   BIOCHEMISTRY

Copper(II) Binding to Amyloid-β Fibrils of Alzheimer’s Disease Reveals a Picomolar Affinity: Stoichiometry and Coordination Geometry Are Independent of Aβ Oligomeric Form

(2009) Claire J. Sarell et al.   BIOCHEMISTRY

Aβ-mediated ROS production by Cu ions: Structural insights, mechanisms and relevance to Alzheimer's disease

(2009) Christelle Hureau et al.   BIOCHIMIE

Copper and Zinc Binding to Amyloid-β: Coordination, Dynamics, Aggregation, Reactivity and Metal-Ion Transfer

(2009) Peter Faller   CHEMBIOCHEM

Fenton chemistry and oxidative stress mediate the toxicity of the β-amyloid peptide in aDrosophilamodel of Alzheimer’s disease

(2009) Thomas Rival et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Zn(II)- and Cu(II)-induced non-fibrillar aggregates of amyloid-β (1-42) peptide are transformed to amyloid fibrils, both spontaneously and under the influence of metal chelators

(2009) Vello Tõugu et al.   JOURNAL OF NEUROCHEMISTRY

Pleomorphic Copper Coordination by Alzheimer’s Disease Amyloid-β Peptide

(2009) Simon C. Drew et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Increasing Cu bioavailability inhibits A  oligomers and tau phosphorylation

(2009) P. J. Crouch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amyloid β−Cu2+Complexes in both Monomeric and Fibrillar Forms Do Not Generate H2O2Catalytically but Quench Hydroxyl Radicals†

(2008) Rebecca C. Nadal et al.   BIOCHEMISTRY

Direct Evidence That All Three Histidine Residues Coordinate to Cu(II) in Amyloid-β1−16†

(2008) Byong-kyu Shin et al.   BIOCHEMISTRY

Cu(II) Binding to Monomeric, Oligomeric, and Fibrillar Forms of the Alzheimer’s Disease Amyloid-β Peptide†

(2008) Jesse W. Karr et al.   BIOCHEMISTRY

Fitting Neurological Protein Aggregation Kinetic Data via a 2-Step, Minimal/“Ockham's Razor” Model:  The Finke−Watzky Mechanism of Nucleation Followed by Autocatalytic Surface Growth†

(2008) Aimee M. Morris et al.   BIOCHEMISTRY

The Structure of the Amyloid-β Peptide High-Affinity Copper II Binding Site in Alzheimer Disease

(2008) Victor A. Streltsov et al.   BIOPHYSICAL JOURNAL

Metals in Alzheimer's and Parkinson's Diseases

(2008) Kevin J Barnham et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

The Metal Loading Ability of β-Amyloid N-Terminus: A Combined Potentiometric and Spectroscopic Study of Copper(II) Complexes with β-Amyloid(1−16), Its Short or Mutated Peptide Fragments, and Its Polyethylene Glycol (PEG)-ylated Analogue

(2008) Chiara A. Damante et al.   INORGANIC CHEMISTRY

Amyloid β-Protein Toxicity and the Pathogenesis of Alzheimer Disease

(2008) Bruce A. Yankner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Classification of Toxic Amyloid Oligomers

(2008) Charles G. Glabe   JOURNAL OF BIOLOGICAL CHEMISTRY

Identifying the Minimal Copper- and Zinc-binding Site Sequence in Amyloid-β Peptides

(2008) Velia Minicozzi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amyloid β-Protein Assembly and Alzheimer Disease

(2008) Robin Roychaudhuri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rapid appearance and local toxicity of amyloid-β plaques in a mouse model of Alzheimer’s disease

(2008) Melanie Meyer-Luehmann et al.   NATURE

Metal swap between Zn7-metallothionein-3 and amyloid-β–Cu protects against amyloid-β toxicity

(2008) Gabriele Meloni et al.   Nature Chemical Biology

A regulatable switch mediates self-association in an immunoglobulin fold

(2008) Matthew F Calabrese et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY