Hypoxia-inducible factor-1 alpha-dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa
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Title
Hypoxia-inducible factor-1 alpha-dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa
Authors
Keywords
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Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 109, Issue 41, Pages E2784-E2793
Publisher
Proceedings of the National Academy of Sciences
Online
2012-09-18
DOI
10.1073/pnas.1202366109
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- (2011) Holger K. Eltzschig et al. NEW ENGLAND JOURNAL OF MEDICINE
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- (2010) C. T. Ng et al. ANNALS OF THE RHEUMATIC DISEASES
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- Th17 and Regulatory T Cells in Mediating and Restraining Inflammation
- (2010) Dan R. Littman et al. CELL
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- (2010) D. J. Kominsky et al. JOURNAL OF IMMUNOLOGY
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- (2010) W. M. Bernhardt et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Molecular mechanisms regulating TGF-β-induced Foxp3 expression
- (2010) L Xu et al. Mucosal Immunology
- Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate
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- (2009) Peter Fraisl et al. NATURE REVIEWS DRUG DISCOVERY
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- T regulatory cells: hypoxia-adenosinergic suppression and re-direction of the immune response
- (2009) Michail V. Sitkovsky TRENDS IN IMMUNOLOGY
- Oxygen homeostasis
- (2009) Gregg L. Semenza Wiley Interdisciplinary Reviews-Systems Biology and Medicine
- HIF-1-dependent repression of adenosine kinase attenuates hypoxia-induced vascular leak
- (2008) J. C. Morote-Garcia et al. BLOOD
- Endothelial CD47 interaction with SIRP is required for human T-cell transendothelial migration under shear flow conditions in vitro
- (2008) M. Stefanidakis et al. BLOOD
- Hypoxia-Inducible Factor-1 Is Central to Cardioprotection
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