Interaction between Susceptibility and Environment: Examples from the Digestive Tract

Virus-Plus-Susceptibility Gene Interaction Determines Crohn's Disease Gene Atg16L1 Phenotypes in Intestine

(2010) Ken Cadwell et al.   CELL

Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease (IBD)

(2010) R. DUCHMANN et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Pediatric inflammatory bowel diseases: coming of age

(2010) Frank M Ruemmele   CURRENT OPINION IN GASTROENTEROLOGY

Smoking, Physical Activity, Nutrition and Lifestyle: Environmental Factors and Their Impact on IBD

(2010) Jacques Cosnes   DIGESTIVE DISEASES

Risk Factors Associated With Progression to Intestinal Complications of Crohn's Disease in a Population-Based Cohort

(2010) Kelvin T. Thia et al.   GASTROENTEROLOGY

Association between genome-wide association studies reported SNPs and pediatric-onset Crohn’s disease in Canadian children

(2010) Devendra K. Amre et al.   HUMAN GENETICS

Independent and population-specific association of risk variants at the IRGM locus with Crohn's disease

(2010) Natalie J. Prescott et al.   HUMAN MOLECULAR GENETICS

Inflammatory bowel disease in the Asia-Pacific area: A comparison with developed countries and regional differences

(2010) Vineet AHUJA et al.   Journal of Digestive Diseases

Progression of inflammatory bowel disease in China

(2010) Yu Fang WANG et al.   Journal of Digestive Diseases

Prevalence and incidence rates of Crohn's disease in mainland China: A meta-analysis of 55 years of research

(2010) Jia Ju ZHENG et al.   Journal of Digestive Diseases

Postsurgical Recurrence of Ileal Crohn’s Disease: An Update on Risk Factors and Intervention Points to a Central Role for Impaired Host-Microflora Homeostasis

(2010) Michael F. Cunningham et al.   WORLD JOURNAL OF SURGERY

Defective Paneth Cell—Mediated Host Defense in Pediatric Ileal Crohn's Disease

(2009) Gøri Perminow et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

The Genetics of Crohn's Disease

(2009) Johan Van Limbergen et al.   Annual Review of Genomics and Human Genetics

NOD2-associated diseases: Bridging innate immunity and autoinflammation

(2009) Arturo Borzutzky et al.   CLINICAL IMMUNOLOGY

Susceptibility Genes and Overall Pathogenesis of Inflammatory Bowel Disease: Where Do We Stand?

(2009) Claudio Fiocchi   DIGESTIVE DISEASES

The Genetic Basis of Inflammatory Bowel Disease

(2009) Rachel Cooney et al.   DIGESTIVE DISEASES

Disease Behavior in Adult Patients: Are There Predictors for Stricture or Fistula Formation?

(2009) Iris Dotan   DIGESTIVE DISEASES

Defensin-immunology in inflammatory bowel disease

(2009) J. Wehkamp et al.   GASTROENTEROLOGIE CLINIQUE ET BIOLOGIQUE

Environmental risk factors in Crohn's disease and ulcerative colitis: an update

(2009) F. Carbonnel et al.   GASTROENTEROLOGIE CLINIQUE ET BIOLOGIQUE

Nod2 regulates the host response towards microflora by modulating T cell function and epithelial permeability in mouse Peyer's patches

(2009) F. Barreau et al.   GUT

Effects of active and passive smoking on disease course of Crohnʼs disease and ulcerative colitis

(2009) Frans van der Heide et al.   INFLAMMATORY BOWEL DISEASES

Bifidobacterium animalis causes extensive duodenitis and mild colonic inflammation in monoassociated interleukin-10-deficient mice

(2009) James P. Moran et al.   INFLAMMATORY BOWEL DISEASES

Innate antimicrobial host defense in small intestinal Crohn's disease

(2009) Maureen J. Koslowski et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Effect of Proinflammatory Cytokines on the Expression and Regulation of Human Beta-Defensin 2 in Human Dental Pulp Cells

(2009) Young-Suk Kim et al.   JOURNAL OF ENDODONTICS

Common variants at five new loci associated with early-onset inflammatory bowel disease

(2009) Marcin Imielinski et al.   NATURE GENETICS

Common disorders are quantitative traits

(2009) Robert Plomin et al.   NATURE REVIEWS GENETICS

IL-10 and TNF-α promoter haplotypes are associated with childhood Crohn’s disease location

(2009) Rocio Sanchez et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Genome-wide association studies - A summary for theclinical gastroenterologist

(2009) Espen Melum et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Genetics of inflammatory bowel disease: implications for disease pathogenesis and natural history

(2009) Charlie W Lees et al.   Expert Review of Gastroenterology & Hepatology

Is there a role for defensins in IBD?

(2008) Jan Wehkamp et al.   INFLAMMATORY BOWEL DISEASES

The effect of smoking after surgery for Crohn’s disease: a meta-analysis of observational studies

(2008) George E. Reese et al.   INTERNATIONAL JOURNAL OF COLORECTAL DISEASE

Barrier dysfunction due to distinct defensin deficiencies in small intestinal and colonic Crohn's disease

(2008) J Wehkamp et al.   Mucosal Immunology

Crohn’s disease-Defect in innate defence

(2008) Michael Gersemann et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Bacterial Biofilm Suppression with Antibiotics for Ulcerative and Indeterminate Colitis: Consequences of Aggressive Treatment

(2007) Alexander Swidsinski et al.   ARCHIVES OF MEDICAL RESEARCH

Ingested matter affects intestinal lesions in Crohnʼs disease

(2007) Gregor Bartel et al.   INFLAMMATORY BOWEL DISEASES