Downregulation of duodenal SLC transporters and activation of proinflammatory signaling constitute the early response to high altitude in humans

Hypoxia and P1 receptor activation regulate the high-affinity concentrative adenosine transporter CNT2 in differentiated neuronal PC12 cells

(2013) Lorena Medina-Pulido et al.   BIOCHEMICAL JOURNAL

Erythrocytosis: the HIF pathway in control

(2013) K. Franke et al.   BLOOD

Adaptation of iron transport and metabolism to acute high-altitude hypoxia in mountaineers

(2013) Oliver Goetze et al.   HEPATOLOGY

High altitude journeys and flights are associated with an increased risk of flares in inflammatory bowel disease patients

(2013) Stephan R. Vavricka et al.   Journal of Crohns & Colitis

Neuroprotective effects of uridine in a rat model of neonatal hypoxic–ischemic encephalopathy

(2013) Mehmet Cansev et al.   NEUROSCIENCE LETTERS

5-Hydroxytryptamine (serotonin) in the gastrointestinal tract

(2013) Michael D. Gershon   Current Opinion in Endocrinology Diabetes and Obesity

Differential signal pathway activation and 5-HT function: the role of gut enterochromaffin cells as oxygen sensors

(2012) Martin Haugen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Inhibition of gut- and lung-derived serotonin attenuates pulmonary hypertension in mice

(2012) Shariq Abid et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Effect of hypoxia and dexamethasone on inflammation and ion transporter function in pulmonary cells

(2012) M. Urner et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

The updated biology of hypoxia-inducible factor

(2012) Samantha N Greer et al.   EMBO JOURNAL

Disturbed eating at high altitude: influence of food preferences, acute mountain sickness and satiation hormones

(2012) Isabelle Aeberli et al.   EUROPEAN JOURNAL OF NUTRITION

Purinergic Signaling during Inflammation

(2012) Holger K. Eltzschig et al.   NEW ENGLAND JOURNAL OF MEDICINE

Hypoxia-inducible factor-2α and iron absorptive gene expression in Belgrade rat intestine

(2011) Kwo-yih Yeh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

NFκB and HIF display synergistic behaviour during hypoxic inflammation

(2011) Ulrike Bruning et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Hypoxia and Metabolic Factors That Influence Inflammatory Bowel Disease Pathogenesis

(2011) Louise E. Glover et al.   GASTROENTEROLOGY

Dexamethasone Improves Maximal Exercise Capacity of Individuals Susceptible to High Altitude Pulmonary Edema at 4559 m

(2011) Christoph Siebenmann et al.   HIGH ALTITUDE MEDICINE & BIOLOGY

Hypoxia: Adapting to High Altitude by Mutating EPAS-1, the Gene Encoding HIF-2α

(2011) Martha C. Tissot van Patot et al.   HIGH ALTITUDE MEDICINE & BIOLOGY

IL23R, ATG16L1, IRGM, OCTN1, and OCTN2 mRNA expression in inflamed and noninflamed mucosa of IBD patients

(2011) Orazio Palmieri et al.   INFLAMMATORY BOWEL DISEASES

Electrogenic transport, oxygen consumption, and sensitivity to acute hypoxia of human colonic epithelium

(2011) Graciela E. Carra et al.   INTERNATIONAL JOURNAL OF COLORECTAL DISEASE

Hypoxia and Inflammation

(2011) Holger K. Eltzschig et al.   NEW ENGLAND JOURNAL OF MEDICINE

Oxygen Sensing, Homeostasis, and Disease

(2011) Gregg L. Semenza   NEW ENGLAND JOURNAL OF MEDICINE

Drug uptake transporters in antiretroviral therapy

(2011) Gerard Minuesa et al.   PHARMACOLOGY & THERAPEUTICS

Relationship between inflammation and tissue hypoxia in a mouse model of chronic colitis

(2010) Norman R. Harris et al.   INFLAMMATORY BOWEL DISEASES

Hypoxia-Mediated Down-Regulation of OCTN2 and PPARα Expression in Human Placentas and in BeWo Cells

(2010) Ting-Ting Chang et al.   MOLECULAR PHARMACEUTICS

Hypoxia: an alarm signal during intestinal inflammation

(2010) Sean P. Colgan et al.   Nature Reviews Gastroenterology & Hepatology

Xenobiotic, Bile Acid, and Cholesterol Transporters: Function and Regulation

(2010) C. D. Klaassen et al.   PHARMACOLOGICAL REVIEWS

L-carnitine, a diet component and organic cation transporter OCTN ligand, displays immunosuppressive properties and abrogates intestinal inflammation

(2009) G. Fortin et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Changes in mRNA Expression Levels of Solute Carrier Transporters in Inflammatory Bowel Disease Patients

(2009) K. A. Wojtal et al.   DRUG METABOLISM AND DISPOSITION

HIF-2α, but not HIF-1α, promotes iron absorption in mice

(2009) Maria Mastrogiannaki et al.   JOURNAL OF CLINICAL INVESTIGATION

Reoxygenation of hypoxia-differentiated dentritic cells induces Th1 and Th17 cell differentiation

(2009) Qun Wang et al.   MOLECULAR IMMUNOLOGY

Adenosine: An immune modulator of inflammatory bowel diseases

(2009) Jeff Huaqing Ye et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Hypoxia inducible factor-1 (HIF-1)-mediated repression of cystic fibrosis transmembrane conductance regulator (CFTR) in the intestinal epithelium

(2008) Wen Zheng et al.   FASEB JOURNAL

Relationship between oxidative stress and HIF-1α mRNA during sustained hypoxia in humans

(2008) Vincent Pialoux et al.   FREE RADICAL BIOLOGY AND MEDICINE

Hypoxia-Inducible Factor–Dependent Repression of Equilibrative Nucleoside Transporter 2 Attenuates Mucosal Inflammation During Intestinal Hypoxia

(2008) Julio C. Morote–Garcia et al.   GASTROENTEROLOGY

Monocytes and dendritic cells in a hypoxic environment: Spotlights on chemotaxis and migration

(2008) Maria Carla Bosco et al.   IMMUNOBIOLOGY