Small RNAs and extracellular vesicles in filarial nematodes: From nematode development to diagnostics

Mechanisms, timescales and principles of trans-generational epigenetic inheritance in animals

(2016) Adam Klosin et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Reversible HuR‐microRNA binding controls extracellular export of miR‐122 and augments stress response

(2016) Kamalika Mukherjee et al.   EMBO REPORTS

Prospects and challenges of CRISPR/Cas genome editing for the study and control of neglected vector-borne nematode diseases

(2016) Mostafa Zamanian et al.   FEBS Journal

Regulation of the host immune system by helminth parasites

(2016) Rick M. Maizels et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes

(2016) Joanna Kowal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A preliminary proteomic characterisation of extracellular vesicles released by the ovine parasitic nematode, Teladorsagia circumcincta

(2016) Thomas Tzelos et al.   VETERINARY PARASITOLOGY

Glucose and Glycogen Metabolism in Brugia malayi Is Associated with Wolbachia Symbiont Fitness

(2016) Denis Voronin et al.   PLoS One

A novel member of the let-7 microRNA family is associated with developmental transitions in filarial nematode parasites

(2015) Alan D Winter et al.   BMC GENOMICS

Rendering the Intractable More Tractable: Tools from Caenorhabditis elegans Ripe for Import into Parasitic Nematodes

(2015) J. D. Ward   GENETICS

The revised microRNA complement of Fasciola hepatica reveals a plethora of overlooked microRNAs and evidence for enrichment of immuno-regulatory microRNAs in extracellular vesicles

(2015) B. Fromm et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Functional analysis of microRNA activity in Brugia malayi

(2015) Canhui Liu et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Carcinogenic Liver Fluke Secretes Extracellular Vesicles That Promote Cholangiocytes to Adopt a Tumorigenic Phenotype

(2015) Sujittra Chaiyadet et al.   JOURNAL OF INFECTIOUS DISEASES

Secretion of RNA-Containing Extracellular Vesicles by the Porcine Whipworm,Trichuris suis

(2015) Eline Palm Hansen et al.   JOURNAL OF PARASITOLOGY

The Extracellular Vesicles of the Helminth Pathogen,Fasciola hepatica: Biogenesis Pathways and Cargo Molecules Involved in Parasite Pathogenesis

(2015) Krystyna Cwiklinski et al.   MOLECULAR & CELLULAR PROTEOMICS

Extracellular Onchocerca-derived small RNAs in host nodules and blood

(2015) Juan F Quintana et al.   Parasites & Vectors

Exosome-like vesicles derived by Schistosoma japonicum adult worms mediates M1 type immune- activity of macrophage

(2015) Lifu Wang et al.   PARASITOLOGY RESEARCH

Expanding the MDx toolbox for filarial diagnosis and surveillance

(2015) Andy Alhassan et al.   TRENDS IN PARASITOLOGY

Exosomes and Other Extracellular Vesicles: The New Communicators in Parasite Infections

(2015) Gillian Coakley et al.   TRENDS IN PARASITOLOGY

Application of small RNA technology for improved control of parasitic helminths

(2015) Collette Britton et al.   VETERINARY PARASITOLOGY

Ancient and Novel Small RNA Pathways Compensate for the Loss of piRNAs in Multiple Independent Nematode Lineages

(2015) Peter Sarkies et al.   PLOS BIOLOGY

Circulating miRNAs: Potential Novel Biomarkers for Hepatopathology Progression and Diagnosis of Schistosomiasis Japonica in Two Murine Models

(2015) Pengfei Cai et al.   PLoS Neglected Tropical Diseases

Release of Small RNA-containing Exosome-like Vesicles from the Human Filarial Parasite Brugia malayi

(2015) Mostafa Zamanian et al.   PLoS Neglected Tropical Diseases

Endogenous siRNAs: regulators of internal affairs

(2014) Monica J. Piatek et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Comparative analysis of microRNA profiles between adult Ascaris lumbricoides and Ascaris suum

(2014) Chang-Chun Shao et al.   BMC Veterinary Research

piRNAs: from biogenesis to function

(2014) E.-M. Weick et al.   DEVELOPMENT

Loa loa and Onchocerca ochengi miRNAs detected in host circulation

(2014) Lucienne Tritten et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Small RNAs break out: the molecular cell biology of mobile small RNAs

(2014) Peter Sarkies et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Comparative functional characterization of the CSR-1 22G-RNA pathway in Caenorhabditis nematodes

(2014) Shikui Tu et al.   NUCLEIC ACIDS RESEARCH

Diversity and Expression of MicroRNAs in the Filarial Parasite, Brugia malayi

(2014) Catherine B. Poole et al.   PLoS One

Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity

(2014) Amy H. Buck et al.   Nature Communications

Trans-kingdom Cross-Talk: Small RNAs on the Move

(2014) Marijn Knip et al.   PLoS Genetics

Parasite-Derived MicroRNAs in Host Serum As Novel Biomarkers of Helminth Infection

(2014) Anna M. Hoy et al.   PLoS Neglected Tropical Diseases

Detection of Circulating Parasite-Derived MicroRNAs in Filarial Infections

(2014) Lucienne Tritten et al.   PLoS Neglected Tropical Diseases

Parasite Extracellular Vesicles: Mediators of Intercellular Communication

(2014) Olivia Twu et al.   PLoS Pathogens

The Role of Extracellular Vesicles in Modulating the Host Immune Response during Parasitic Infections

(2014) Sergio Montaner et al.   Frontiers in Immunology

From early lessons to new frontiers: the worm as a treasure trove of small RNA biology

(2014) Elaine M. Youngman et al.   Frontiers in Genetics

Functional diversification of Argonautes in nematodes: an expanding universe: Figure 1

(2013) Amy H. Buck et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Malaria-Infected Erythrocyte-Derived Microvesicles Mediate Cellular Communication within the Parasite Population and with the Host Immune System

(2013) Pierre-Yves Mantel et al.   Cell Host & Microbe

A multitasking Argonaute: exploring the many facets of C. elegans CSR-1

(2013) Christopher J. Wedeles et al.   CHROMOSOME RESEARCH

Argonaute proteins: functional insights and emerging roles

(2013) Gunter Meister   NATURE REVIEWS GENETICS

miRBase: annotating high confidence microRNAs using deep sequencing data

(2013) Ana Kozomara et al.   NUCLEIC ACIDS RESEARCH

Localization of Wolbachia-like gene transcripts and peptides in adult Onchocerca flexuosa worms indicates tissue specific expression

(2013) Samantha N McNulty et al.   Parasites & Vectors

Deep sequencing-based identification of pathogen-specific microRNAs in the plasma of rabbits infected with Schistosoma japonicum

(2013) GUOFENG CHENG et al.   PARASITOLOGY

Comparative profiling of microRNAs in male and female adults of Ascaris suum

(2013) Min-Jun Xu et al.   PARASITOLOGY RESEARCH

RNAi pathways contribute to developmental history-dependent phenotypic plasticity in C. elegans

(2013) S. E. Hall et al.   RNA

Is There Social RNA?

(2013) P. Sarkies et al.   SCIENCE

Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specific motifs

(2013) Carolina Villarroya-Beltri et al.   Nature Communications

Microvesicles and intercellular communication in the context of parasitism

(2013) Natasha S. Barteneva et al.   Frontiers in Cellular and Infection Microbiology

Helminth defence molecules—immunomodulators designed by parasites!

(2013) Mark W. Robinson et al.   Frontiers in Microbiology

Circulating miRNAs: cell–cell communication function?

(2013) A. Turchinovich et al.   Frontiers in Genetics

Extracellular small RNAs: what, where, why?: Figure 1

(2012) Anna M. Hoy et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Diversity in parasitic nematode genomes: the microRNAs of Brugia pahangi and Haemonchus contortus are largely novel

(2012) Alan D Winter et al.   BMC GENOMICS

The C. elegans MicroRNA mir-71 Acts in Neurons to Promote Germline-Mediated Longevity through Regulation of DAF-16/FOXO

(2012) Konstantinos Boulias et al.   Cell Metabolism

MicroRNA profiling: approaches and considerations

(2012) Colin C. Pritchard et al.   NATURE REVIEWS GENETICS

Extracellular Vesicles from Parasitic Helminths Contain Specific Excretory/Secretory Proteins and Are Internalized in Intestinal Host Cells

(2012) Antonio Marcilla et al.   PLoS One

The onchocerciasis chronicle: from the beginning to the end?

(2012) Andy Crump et al.   TRENDS IN PARASITOLOGY

Macroparasite Life Histories

(2011) Mark Viney et al.   CURRENT BIOLOGY

MicroRNA evolution by arm switching

(2011) Sam Griffiths-Jones et al.   EMBO REPORTS

Deep small RNA sequencing from the nematode Ascaris reveals conservation, functional diversification, and novel developmental profiles

(2011) J. Wang et al.   GENOME RESEARCH

Effect of life history on microRNA expression during C. elegans development

(2011) X. Karp et al.   RNA

An eye on RNAi in nematode parasites

(2011) Aaron G. Maule et al.   TRENDS IN PARASITOLOGY

RNAi Effector Diversity in Nematodes

(2011) Johnathan J. Dalzell et al.   PLoS Neglected Tropical Diseases

Tissue and Stage-Specific Distribution of Wolbachia in Brugia malayi

(2011) Kerstin Fischer et al.   PLoS Neglected Tropical Diseases

Lymphatic filariasis and onchocerciasis

(2010) Mark J Taylor et al.   LANCET

Filarial Parasites Develop Faster and Reproduce Earlier in Response to Host Immune Effectors That Determine Filarial Life Expectancy

(2010) Simon A. Babayan et al.   PLOS BIOLOGY

Parasite Evolution and Life History Theory

(2010) Beth F. Kochin et al.   PLOS BIOLOGY

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Repertoire and evolution of miRNA genes in four divergent nematode species

(2009) E. de Wit et al.   GENOME RESEARCH

Cloning and bioinformatic identification of small RNAs in the filarial nematode, Brugia malayi

(2009) Catherine B. Poole et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Distinct Argonaute-Mediated 22G-RNA Pathways Direct Genome Surveillance in the C. elegans Germline

(2009) Weifeng Gu et al.   MOLECULAR CELL

Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity

(2009) Derrick J. Gibbings et al.   NATURE CELL BIOLOGY

Many roads to maturity: microRNA biogenesis pathways and their regulation

(2009) Julia Winter et al.   NATURE CELL BIOLOGY

Small silencing RNAs: an expanding universe

(2009) Megha Ghildiyal et al.   NATURE REVIEWS GENETICS

Biogenesis of small RNAs in animals

(2009) V. Narry Kim et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Lymphatic Vascularisation and Involvement of Lyve-1+ Macrophages in the Human Onchocerca Nodule

(2009) Tarik Attout et al.   PLoS One

C. elegans dauer formation and the molecular basis of plasticity

(2008) N. Fielenbach et al.   GENES & DEVELOPMENT

Argonaute proteins: key players in RNA silencing

(2007) Gyorgy Hutvagner et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY