Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity

IL-33, a Potent Inducer of Adaptive Immunity to Intestinal Nematodes

(2014) N. E. Humphreys et al.   JOURNAL OF IMMUNOLOGY

Surface analysis of Dicrocoelium dendriticum. The molecular characterization of exosomes reveals the presence of miRNAs

(2014) Dolores Bernal et al.   Journal of Proteomics

Blockade of IL-33 release and suppression of type 2 innate lymphoid cell responses by helminth secreted products in airway allergy

(2014) H J McSorley et al.   Mucosal Immunology

Parasite-Derived MicroRNAs in Host Serum As Novel Biomarkers of Helminth Infection

(2014) Anna M. Hoy et al.   PLoS Neglected Tropical Diseases

Detection of Circulating Parasite-Derived MicroRNAs in Filarial Infections

(2014) Lucienne Tritten et al.   PLoS Neglected Tropical Diseases

Functional diversification of Argonautes in nematodes: an expanding universe: Figure 1

(2013) Amy H. Buck et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

IL-6 controls susceptibility to helminth infection by impeding Th2 responsiveness and altering the Treg phenotype in vivo

(2013) Katherine A. Smith et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

miRNAs: Small Genes with Big Potential in Metazoan Phylogenetics

(2013) James E. Tarver et al.   MOLECULAR BIOLOGY AND EVOLUTION

The UCSC Genome Browser database: 2014 update

(2013) Donna Karolchik et al.   NUCLEIC ACIDS RESEARCH

Secretion of Protective Antigens by Tissue-Stage Nematode Larvae Revealed by Proteomic Analysis and Vaccination-Induced Sterile Immunity

(2013) James P. Hewitson et al.   PLoS Pathogens

Trichomonas vaginalis Exosomes Deliver Cargo to Host Cells and Mediate Host∶Parasite Interactions

(2013) Olivia Twu et al.   PLoS Pathogens

Circulating miRNAs: cell–cell communication function?

(2013) A. Turchinovich et al.   Frontiers in Genetics

Extracellular small RNAs: what, where, why?: Figure 1

(2012) Anna M. Hoy et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Helminth Infections and Host Immune Regulation

(2012) H. J. McSorley et al.   CLINICAL MICROBIOLOGY REVIEWS

Biogenesis of Y RNA-derived small RNAs is independent of the microRNA pathway

(2012) Francisco Esteban Nicolas et al.   FEBS LETTERS

GATA2 Is a Critical Transactivator for the HumanIL1RL1/ST2Promoter in Mast Cells/Basophils

(2012) Yosuke Baba et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Syndecan–syntenin–ALIX regulates the biogenesis of exosomes

(2012) Maria Francesca Baietti et al.   NATURE CELL BIOLOGY

Deep sequencing of RNA from immune cell-derived vesicles uncovers the selective incorporation of small non-coding RNA biotypes with potential regulatory functions

(2012) Esther N. M. Nolte-’t Hoen et al.   NUCLEIC ACIDS RESEARCH

Deep-Sequencing Protocols Influence the Results Obtained in Small-RNA Sequencing

(2012) Joern Toedling et al.   PLoS One

Extracellular Vesicles from Parasitic Helminths Contain Specific Excretory/Secretory Proteins and Are Internalized in Intestinal Host Cells

(2012) Antonio Marcilla et al.   PLoS One

The Complex Exogenous RNA Spectra in Human Plasma: An Interface with Human Gut Biota?

(2012) Kai Wang et al.   PLoS One

Exogenous plant MIR168a specifically targets mammalian LDLRAP1: evidence of cross-kingdom regulation by microRNA

(2011) Lin Zhang et al.   CELL RESEARCH

Immune modulation and modulators in Heligmosomoides polygyrus infection

(2011) Rick M. Maizels et al.   EXPERIMENTAL PARASITOLOGY

Shotgun proteomic analysis of the unicellular alga Ostreococcus tauri

(2011) Thierry Le Bihan et al.   Journal of Proteomics

Proteomic analysis of secretory products from the model gastrointestinal nematode Heligmosomoides polygyrus reveals dominance of Venom Allergen-Like (VAL) proteins

(2011) James P. Hewitson et al.   Journal of Proteomics

miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades

(2011) Marc R. Friedländer et al.   NUCLEIC ACIDS RESEARCH

Murine cytomegalovirus encodes a miR-27 inhibitor disguised as a target

(2011) V. Libri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Many Families of C. elegans MicroRNAs Are Not Essential for Development or Viability

(2010) Ezequiel Alvarez-Saavedra et al.   CURRENT BIOLOGY

An exosome-based secretion pathway is responsible for protein export from Leishmania and communication with macrophages

(2010) Judith Maxwell Silverman et al.   JOURNAL OF CELL SCIENCE

Helminth secretions induce de novo T cell Foxp3 expression and regulatory function through the TGF-β pathway

(2010) John R. Grainger et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Nematode sbRNAs: Homologs of Vertebrate Y RNAs

(2010) Ilenia Boria et al.   JOURNAL OF MOLECULAR EVOLUTION

rtracklayer: an R package for interfacing with genome browsers

(2009) M. Lawrence et al.   BIOINFORMATICS

C-type lectins from the nematode parasites Heligmosomoides polygyrus and Nippostrongylus brasiliensis

(2009) Yvonne Harcus et al.   PARASITOLOGY INTERNATIONAL

ExoCarta: A compendium of exosomal proteins and RNA

(2009) Suresh Mathivanan et al.   PROTEOMICS

lumi: a pipeline for processing Illumina microarray

(2008) P. Du et al.   BIOINFORMATICS

Functional Analysis of Effector and Regulatory T Cells in a Parasitic Nematode Infection

(2008) S. Rausch et al.   INFECTION AND IMMUNITY

Model-based variance-stabilizing transformation for Illumina microarray data

(2008) Simon M. Lin et al.   NUCLEIC ACIDS RESEARCH

Intestinal Transcriptomes of Nematodes: Comparison of the Parasites Ascaris suum and Haemonchus contortus with the Free-living Caenorhabditis elegans

(2008) Yong Yin et al.   PLoS Neglected Tropical Diseases