Stimulators and activators of soluble guanylate cyclase for urogenital disorders
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Stimulators and activators of soluble guanylate cyclase for urogenital disorders
Authors
Keywords
-
Journal
Nature Reviews Urology
Volume 15, Issue 1, Pages 42-54
Publisher
Springer Nature
Online
2017-11-14
DOI
10.1038/nrurol.2017.181
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- European Association of Urology Position Statement on the Role of the Urologist in the Management of Male Hypogonadism and Testosterone Therapy
- (2017) Vincenzo Mirone et al. EUROPEAN UROLOGY
- Erectile Dysfunction in Heme-Deficient Nitric Oxide–Unresponsive Soluble Guanylate Cyclase Knock-In Mice
- (2017) Kelly Decaluwé et al. Journal of Sexual Medicine
- Nocturnal Polyuria and Hypertension in Patients with Lifestyle Related Diseases and Overactive Bladder
- (2017) Osamu Yokoyama et al. JOURNAL OF UROLOGY
- Testosterone undecanoate improves sexual function in men with type 2 diabetes and severe hypogonadism: results from a 30-week randomized placebo-controlled study
- (2016) Geoffrey Hackett et al. BJU INTERNATIONAL
- Latest Evidence on the Use of Phosphodiesterase Type 5 Inhibitors for the Treatment of Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia
- (2016) Mauro Gacci et al. EUROPEAN UROLOGY
- Translational Perspective on the Role of Testosterone in Sexual Function and Dysfunction
- (2016) Carol A. Podlasek et al. Journal of Sexual Medicine
- Lower urinary tract symptoms, benign prostatic hyperplasia and metabolic syndrome
- (2016) Linda Vignozzi et al. Nature Reviews Urology
- Implication of Rho-kinase and soluble guanylyl cyclase enzymes in prostate smooth muscle dysfunction in middle-aged rats
- (2016) Fabiano B. Calmasini et al. NEUROUROLOGY AND URODYNAMICS
- Effects of Testosterone Treatment in Older Men
- (2016) Peter J. Snyder et al. NEW ENGLAND JOURNAL OF MEDICINE
- Regulation of soluble guanylyl cyclase redox state by hydrogen sulfide
- (2016) Zongmin Zhou et al. PHARMACOLOGICAL RESEARCH
- Soluble Guanylate Cyclase Modulators, BAY 41-2272 and BAY 60-2770, Inhibit Human and Rabbit Prostate Contractility
- (2016) Fabiano B. Calmasini et al. UROLOGY
- Pharmacological characterisation of the relaxation induced by the soluble guanylate cyclase activator, BAY 60-2770 in rabbit corpus cavernosum
- (2015) Camila S. Estancial et al. BJU INTERNATIONAL
- Increased Rho-kinase-mediated prostate contractions associated with impairment of β-adrenergic-cAMP-signaling pathway by chronic nitric oxide deficiency
- (2015) Fabiano Beraldi Calmasini et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- The comparison of GLUT-4 and nNOS expression in diabetic and non-diabetic patients with BPH/LUTS
- (2015) Alper Otunctemur et al. INTERNATIONAL UROLOGY AND NEPHROLOGY
- Diagnosis and Treatment of Interstitial Cystitis/Bladder Pain Syndrome: AUA Guideline Amendment
- (2015) Philip M. Hanno et al. JOURNAL OF UROLOGY
- Novel methods for mapping the cavernous nerves during radical prostatectomy
- (2015) Nathaniel M. Fried et al. Nature Reviews Urology
- Cardiovascular and pharmacological implications of haem-deficient NO-unresponsive soluble guanylate cyclase knock-in mice
- (2015) Robrecht Thoonen et al. Nature Communications
- Oxidative stress associated with middle aging leads to sympathetic hyperactivity and downregulation of soluble guanylyl cyclase in corpus cavernosum
- (2014) Fábio H. Silva et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Stimulation of the soluble guanylate cyclase (sGC) inhibits fibrosis by blocking non-canonical TGFβ signalling
- (2014) Christian Beyer et al. ANNALS OF THE RHEUMATIC DISEASES
- Blockade of renin–angiotensin system prevents micturition dysfunction in renovascular hypertensive rats
- (2014) Antonio Celso S. Ramos-Filho et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Prolonged Therapy with the Soluble Guanylyl Cyclase Activator BAY 60-2770 Restores the Erectile Function in Obese Mice
- (2014) Fábio H. Silva et al. Journal of Sexual Medicine
- Reduction of obstruction related bladder overactivity by the guanylyl cyclase modulators BAY 41-2272 and BAY 60-2770 alone or in combination with a phosphodiesterase type 5 inhibitor
- (2014) C. Füllhase et al. NEUROUROLOGY AND URODYNAMICS
- The sGC activator BAY 60-2770 has potent erectile activity in the rat
- (2013) George F. Lasker et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Insights into BAY 60-2770 Activation and S-Nitrosylation-Dependent Desensitization of Soluble Guanylyl Cyclase via Crystal Structures of Homologous Nostoc H-NOX Domain Complexes
- (2013) Vijay Kumar et al. BIOCHEMISTRY
- Arterial erectile dysfunction: Different severities of endothelial apoptosis between diabetic patients “responders” and “non responders” to sildenafil
- (2013) Rosita A. Condorelli et al. European Journal of Internal Medicine
- Insulin relaxes bladder via PI3K/AKT/eNOS pathway activation in mucosa: unfolded protein response-dependent insulin resistance as a cause of obesity-associated overactive bladder
- (2013) Luiz O. Leiria et al. JOURNAL OF PHYSIOLOGY-LONDON
- Synergistic Effects of BAY 60‐4552 and Vardenafil on Relaxation of Corpus Cavernosum Tissue of Patients with Erectile Dysfunction and Clinical Phosphodiesterase Type 5 Inhibitor Failure
- (2013) Maarten Albersen et al. Journal of Sexual Medicine
- Superoxide Anion Production by NADPH Oxidase Plays a Major Role in Erectile Dysfunction in Middle‐Aged Rats: Prevention by Antioxidant Therapy
- (2013) Fábio H. Silva et al. Journal of Sexual Medicine
- Treatment Status and Progression or Regression of Lower Urinary Tract Symptoms in a General Adult Population Sample
- (2013) Nancy N. Maserejian et al. JOURNAL OF UROLOGY
- The Soluble Guanylyl Cyclase Activator BAY 60-2770 Ameliorates Overactive Bladder in Obese Mice
- (2013) Luiz O. Leiria et al. JOURNAL OF UROLOGY
- The role of phosphodiesterases in bladder pathophysiology
- (2013) Mohammad S. Rahnama'i et al. Nature Reviews Urology
- Targeted therapies in pulmonary arterial hypertension
- (2013) David Montani et al. PHARMACOLOGY & THERAPEUTICS
- BAY 41-2272, a Soluble Guanylate Cyclase Stimulator, Relaxes Isolated Human Ureter in a Standardized In Vitro Model
- (2013) Ricardo Miyaoka et al. UROLOGY
- Structure and Regulation of Soluble Guanylate Cyclase
- (2012) Emily R. Derbyshire et al. Annual Review of Biochemistry
- Central obesity as measured by waist circumference is predictive of severity of lower urinary tract symptoms
- (2012) Richard K. Lee et al. BJU INTERNATIONAL
- Analysis of Erectile Responses to BAY 41-8543 and Muscarinic Receptor Stimulation in the Rat
- (2012) George F. Lasker et al. Journal of Sexual Medicine
- Activation of Haem-Oxidized Soluble Guanylyl Cyclase with BAY 60-2770 in Human Platelets Lead to Overstimulation of the Cyclic GMP Signaling Pathway
- (2012) Camila B. Mendes-Silverio et al. PLoS One
- Functional, morphological and molecular characterization of bladder dysfunction in streptozotocin-induced diabetic mice: evidence of a role for L-type voltage-operated Ca2+channels
- (2011) LOS Leiria et al. BRITISH JOURNAL OF PHARMACOLOGY
- Nitric Oxide and Cyclic GMP Signaling Pathway as a Focus for Drug Development
- (2011) A.Y. Kots et al. CURRENT MEDICINAL CHEMISTRY
- Efficacy and Safety of Tadalafil Once Daily in the Treatment of Men With Lower Urinary Tract Symptoms Suggestive of Benign Prostatic Hyperplasia: Results of an International Randomized, Double-Blind, Placebo-Controlled Trial
- (2011) Hartmut Porst et al. EUROPEAN UROLOGY
- Obesity Increases and Physical Activity Decreases Lower Urinary Tract Symptom Risk in Older Men: The Osteoporotic Fractures in Men Study
- (2011) J. Kellogg Parsons et al. EUROPEAN UROLOGY
- Combination of BAY 60-4552 and Vardenafil Exerts Proerectile Facilitator Effects in Rats With Cavernous Nerve Injury: A Proof of Concept Study for the Treatment of Phosphodiesterase Type 5 Inhibitor Failure
- (2011) Alexandra Oudot et al. EUROPEAN UROLOGY
- Tadalafil versus solifenacin for persistent storage symptoms after prostate surgery in patients with erectile dysfunction: A prospective randomized study
- (2011) Guevar Maselli et al. INTERNATIONAL JOURNAL OF UROLOGY
- Obesity, Physical Activity and Lower Urinary Tract Symptoms: Results From the Southern Community Cohort Study
- (2011) David F. Penson et al. JOURNAL OF UROLOGY
- Restoring Soluble Guanylyl Cyclase Expression and Function Blocks the Aggressive Course of Glioma
- (2011) H. Zhu et al. MOLECULAR PHARMACOLOGY
- Urological aspects of the metabolic syndrome
- (2011) Jan Hammarsten et al. Nature Reviews Urology
- Cyclic GMP signaling in rat urinary bladder, prostate, and epididymis: tissue-specific changes with aging and in response to Leydig cell depletion
- (2011) Dieter Müller et al. REPRODUCTION
- cGMP increases antioxidant function and attenuates oxidant cell death in mouse lung microvascular endothelial cells by a protein kinase G-dependent mechanism
- (2010) R. Scott Stephens et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Chronic alcoholism associated with diabetes impairs erectile function in rats
- (2010) Fermino S. Lizarte et al. BJU INTERNATIONAL
- High-fat diet associated with obesity induces impairment of mouse corpus cavernosum responses
- (2010) Haroldo A. Toque et al. BJU INTERNATIONAL
- Long-term oral treatment with BAY 41-2272 ameliorates impaired corpus cavernosum relaxations in a nitric oxide-deficient rat model
- (2010) Mário A. Claudino et al. BJU INTERNATIONAL
- Evaluation of the relaxant effect of the nitric oxide-independent soluble guanylyl cyclase stimulator BAY 41-2272 in isolated detrusor smooth muscle
- (2010) Fernando R. Báu et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Structure of Cinaciguat (BAY 58–2667) Bound toNostocH-NOX Domain Reveals Insights into Heme-mimetic Activation of the Soluble Guanylyl Cyclase
- (2010) Faye Martin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- cGMP-Dependent Protein Kinases and cGMP Phosphodiesterases in Nitric Oxide and cGMP Action
- (2010) S. H. Francis et al. PHARMACOLOGICAL REVIEWS
- Distinct molecular requirements for activation or stabilization of soluble guanylyl cyclase upon haem oxidation-induced degradation
- (2009) LS Hoffmann et al. BRITISH JOURNAL OF PHARMACOLOGY
- Acute Vardenafil Administration Improves Bladder Oxygenation in Spontaneously Hypertensive Rats
- (2009) Annamaria Morelli et al. Journal of Sexual Medicine
- Long-term nitric oxide deficiency causes muscarinic supersensitivity and reduces β3-adrenoceptor-mediated relaxation, causing rat detrusor overactivity
- (2008) F Z T Mónica et al. BRITISH JOURNAL OF PHARMACOLOGY
- Glucose-Dependent Enhancement of Diabetic Bladder Contraction Is Associated with a Rho Kinase-Regulated Protein Kinase C Pathway
- (2008) K. Nobe et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Tadalafil Administered Once Daily for Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia: A Dose Finding Study
- (2008) Claus G. Roehrborn et al. JOURNAL OF UROLOGY
- Pharmacological Properties, Functional Alterations and Gene Expression of Muscarinic Receptors in Young and Old Type 2 Goto-Kakizaki Diabetic Rat Bladders
- (2008) Motoaki Saito et al. JOURNAL OF UROLOGY
- Bladder Dysfunction in Rats With Metabolic Syndrome Induced by Long-Term Fructose Feeding
- (2008) Wei-Chia Lee et al. JOURNAL OF UROLOGY
- Increased Cyclic Guanosine Monophosphate Synthesis and Calcium Entry Blockade Account for the Relaxant Activity of the Nitric Oxide–Independent Soluble Guanylyl Cyclase Stimulator BAY 41-2272 in the Rabbit Penile Urethra
- (2008) Haroldo A. Flores Toque et al. UROLOGY
- Diagnostic Criteria, Classification, and Nomenclature for Painful Bladder Syndrome/Interstitial Cystitis: An ESSIC Proposal
- (2007) Joop P. van de Merwe et al. EUROPEAN UROLOGY
- Relationship Between Lower Urinary Tract Symptoms and Erectile Dysfunction: Results From the Boston Area Community Health Survey
- (2007) Sara T. Brookes et al. JOURNAL OF UROLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More