Intestinal lymphatic vasculature: structure, mechanisms and functions

Glyceride-Mimetic Prodrugs Incorporating Self-Immolative Spacers Promote Lymphatic Transport, Avoid First-Pass Metabolism, and Enhance Oral Bioavailability

(2016) Luojuan Hu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Lymphangiogenesis: Origin, Specification, and Cell Fate Determination

(2016) Noelia Escobedo et al.   Annual Review of Cell and Developmental Biology

Lymphovenous hemostasis and the role of platelets in regulating lymphatic flow and lymphatic vessel maturation

(2016) J. D. Welsh et al.   BLOOD

Heterogeneity in the lymphatic vascular system and its origin

(2016) Maria H. Ulvmar et al.   CARDIOVASCULAR RESEARCH

The Cardiovascular Biology of Glucagon-like Peptide-1

(2016) Daniel J. Drucker   Cell Metabolism

Lymphatic System in Cardiovascular Medicine

(2016) Aleksanteri Aspelund et al.   CIRCULATION RESEARCH

Regulation of lipid metabolism by angiopoietin-like proteins

(2016) Wieneke Dijk et al.   CURRENT OPINION IN LIPIDOLOGY

The lymphatic vasculature: development and role in shaping immunity

(2016) Kelly L. Betterman et al.   IMMUNOLOGICAL REVIEWS

CCR7 and IRF4-dependent dendritic cells regulate lymphatic collecting vessel permeability

(2016) Stoyan Ivanov et al.   JOURNAL OF CLINICAL INVESTIGATION

Lymphatic endothelial cells are a replicative niche for Mycobacterium tuberculosis

(2016) Thomas R. Lerner et al.   JOURNAL OF CLINICAL INVESTIGATION

Proteolytic activation defines distinct lymphangiogenic mechanisms for VEGFC and VEGFD

(2016) Hung M. Bui et al.   JOURNAL OF CLINICAL INVESTIGATION

Lymphatic pumping: mechanics, mechanisms and malfunction

(2016) Joshua P. Scallan et al.   JOURNAL OF PHYSIOLOGY-LONDON

Angiocrine functions of organ-specific endothelial cells

(2016) Shahin Rafii et al.   NATURE

High-resolution 3D analysis of mouse small-intestinal stroma

(2016) Jeremiah Bernier-Latmani et al.   Nature Protocols

The tumor microenvironment and Immunoscore are critical determinants of dissemination to distant metastasis

(2016) Bernhard Mlecnik et al.   Science Translational Medicine

ADAMTS3 activity is mandatory for embryonic lymphangiogenesis and regulates placental angiogenesis

(2015) Lauriane Janssen et al.   ANGIOGENESIS

New Insights into the Regulation of Chylomicron Production

(2015) Satya Dash et al.   Annual Review of Nutrition

Microbiota-Dependent Sequelae of Acute Infection Compromise Tissue-Specific Immunity

(2015) Denise Morais da Fonseca et al.   CELL

Tie1 is required for lymphatic valve and collecting vessel development

(2015) Xianghu Qu et al.   DEVELOPMENTAL BIOLOGY

VEGF‐C is required for intestinal lymphatic vessel maintenance and lipid absorption

(2015) Harri Nurmi et al.   EMBO Molecular Medicine

The lymphatic phenotype in Turner syndrome: an evaluation of nineteen patients and literature review

(2015) Giles Atton et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Vascular Endothelial Growth Factor C Disrupts the Endothelial Lymphatic Barrier to Promote Colorectal Cancer Invasion

(2015) Carlotta Tacconi et al.   GASTROENTEROLOGY

Biomimetic reassembled chylomicrons as novel association model for the prediction of lymphatic transportation of highly lipophilic drugs via the oral route

(2015) Yi Lu et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

GATA2 is required for lymphatic vessel valve development and maintenance

(2015) Jan Kazenwadel et al.   JOURNAL OF CLINICAL INVESTIGATION

DLL4 promotes continuous adult intestinal lacteal regeneration and dietary fat transport

(2015) Jeremiah Bernier-Latmani et al.   JOURNAL OF CLINICAL INVESTIGATION

Intravital imaging of intestinal lacteals unveils lipid drainage through contractility

(2015) Kibaek Choe et al.   JOURNAL OF CLINICAL INVESTIGATION

FOXC2 and fluid shear stress stabilize postnatal lymphatic vasculature

(2015) Amélie Sabine et al.   JOURNAL OF CLINICAL INVESTIGATION

Lymph flow regulates collecting lymphatic vessel maturation in vivo

(2015) Daniel T. Sweet et al.   JOURNAL OF CLINICAL INVESTIGATION

Gut/brain axis and the microbiota

(2015) Emeran A. Mayer et al.   JOURNAL OF CLINICAL INVESTIGATION

Type 3 innate lymphoid cells maintain intestinal epithelial stem cells after tissue damage

(2015) Patricia Aparicio-Domingo et al.   JOURNAL OF EXPERIMENTAL MEDICINE

ABCG5/G8 Deficiency in Mice Reduces Dietary Triacylglycerol and Cholesterol Transport into the Lymph

(2015) Linda S. Zhang et al.   LIPIDS

The lymph nodes draining the small intestine and colon are anatomically separate and immunologically distinct

(2015) S A Houston et al.   Mucosal Immunology

Innate lymphoid cells in the initiation, regulation and resolution of inflammation

(2015) Gregory F Sonnenberg et al.   NATURE MEDICINE

The consensus molecular subtypes of colorectal cancer

(2015) Justin Guinney et al.   NATURE MEDICINE

From sewer to saviour — targeting the lymphatic system to promote drug exposure and activity

(2015) Natalie L. Trevaskis et al.   NATURE REVIEWS DRUG DISCOVERY

Immunopathogenesis of IBD: current state of the art

(2015) Heitor S. P. de Souza et al.   Nature Reviews Gastroenterology & Hepatology

VEGFR3 does not sustain retinal angiogenesis without VEGFR2

(2015) Georgia Zarkada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Emerging trends in the pathophysiology of lymphatic contractile function

(2015) Sanjukta Chakraborty et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

CCR7-dependent trafficking of RORγ+ ILCs creates a unique microenvironment within mucosal draining lymph nodes

(2015) Emma C. Mackley et al.   Nature Communications

Microbe-dependent lymphatic migration of neutrophils modulates lymphocyte proliferation in lymph nodes

(2015) Henry R. Hampton et al.   Nature Communications

EphB4 forward signalling regulates lymphatic valve development

(2015) Gu Zhang et al.   Nature Communications

Impaired PIEZO1 function in patients with a novel autosomal recessive congenital lymphatic dysplasia

(2015) Viktor Lukacs et al.   Nature Communications

Novel mutations in PIEZO1 cause an autosomal recessive generalized lymphatic dysplasia with non-immune hydrops fetalis

(2015) Elisavet Fotiou et al.   Nature Communications

cKit Lineage Hemogenic Endothelium-Derived Cells Contribute to Mesenteric Lymphatic Vessels

(2015) Lukas Stanczuk et al.   Cell Reports

Dissemination of a Highly Virulent Pathogen: Tracking The Early Events That Define Infection

(2015) Rodrigo J. Gonzalez et al.   PLoS Pathogens

Rapid Lymphatic Dissemination of Encapsulated Group A Streptococci via Lymphatic Vessel Endothelial Receptor-1 Interaction

(2015) Nicola N. Lynskey et al.   PLoS Pathogens

Feeding-dependent activation of enteric cells and sensory neurons by lymphatic fluid: evidence for a neurolymphocrine system

(2014) Daniel P. Poole et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Genetic Dissection of Tie Pathway in Mouse Lymphatic Maturation and Valve Development

(2014) Bin Shen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Role of the Microbiota in Immunity and Inflammation

(2014) Yasmine Belkaid et al.   CELL

Adipocyte Inflammation Is Essential for Healthy Adipose Tissue Expansion and Remodeling

(2014) Ingrid Wernstedt Asterholm et al.   Cell Metabolism

CCBE1 Enhances Lymphangiogenesis via A Disintegrin and Metalloprotease With Thrombospondin Motifs-3–Mediated Vascular Endothelial Growth Factor-C Activation

(2014) Michael Jeltsch et al.   CIRCULATION

How to make an intestine

(2014) J. M. Wells et al.   DEVELOPMENT

Notch signaling functions in lymphatic valve formation

(2014) A. Murtomaki et al.   DEVELOPMENT

Ccbe1 regulates Vegfc-mediated induction of Vegfr3 signaling during embryonic lymphangiogenesis

(2014) L. Le Guen et al.   DEVELOPMENT

The Left-Right Pitx2 Pathway Drives Organ-Specific Arterial and Lymphatic Development in the Intestine

(2014) Aparna Mahadevan et al.   DEVELOPMENTAL CELL

Spatiotemporal mapping of vascularization and innervation in the fetal murine intestine

(2014) John Hatch et al.   DEVELOPMENTAL DYNAMICS

Angiopoietin 2 regulates the transformation and integrity of lymphatic endothelial cell junctions

(2014) W. Zheng et al.   GENES & DEVELOPMENT

Hennekam syndrome can be caused by FAT4 mutations and be allelic to Van Maldergem syndrome

(2014) Mariëlle Alders et al.   HUMAN GENETICS

Genetics of lymphatic anomalies

(2014) Pascal Brouillard et al.   JOURNAL OF CLINICAL INVESTIGATION

VEGF-C–dependent stimulation of lymphatic function ameliorates experimental inflammatory bowel disease

(2014) Silvia D’Alessio et al.   JOURNAL OF CLINICAL INVESTIGATION

Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature

(2014) Yael Haberman et al.   JOURNAL OF CLINICAL INVESTIGATION

Targeted delivery of a model immunomodulator to the lymphatic system: Comparison of alkyl ester versus triglyceride mimetic lipid prodrug strategies

(2014) Sifei Han et al.   JOURNAL OF CONTROLLED RELEASE

A novel stop mutation in the vascular endothelial growth factor-C gene (VEGFC) results in Milroy-like disease

(2014) Emilia Balboa-Beltran et al.   JOURNAL OF MEDICAL GENETICS

Piezo1 integration of vascular architecture with physiological force

(2014) Jing Li et al.   NATURE

Exploring the Impact of Drug Properties on the Extent of Intestinal Lymphatic Transport - In Vitro and In Vivo Studies

(2014) Emma Lawless et al.   PHARMACEUTICAL RESEARCH

Temporal and spatial regulation of epsin abundance and VEGFR3 signaling are required for lymphatic valve formation and function

(2014) X. Liu et al.   Science Signaling

Intestinal macrophages and dendritic cells: what's the difference?

(2014) Vuk Cerovic et al.   TRENDS IN IMMUNOLOGY

Primary intestinal lymphangiectasia: Minireview

(2014) Sachin B Ingle   World Journal of Clinical Cases

Bone morphogenetic protein 9 (BMP9) controls lymphatic vessel maturation and valve formation

(2013) S. Levet et al.   BLOOD

Conditional ablation of LYVE-1+ cells unveils defensive roles of lymphatic vessels in intestine and lymph nodes

(2013) J. Y. Jang et al.   BLOOD

Lymphatic Vessels Are Essential for the Removal of Cholesterol from Peripheral Tissues by SR-BI-Mediated Transport of HDL

(2013) Hwee Ying Lim et al.   Cell Metabolism

Mutation in Vascular Endothelial Growth Factor-C, a Ligand for Vascular Endothelial Growth Factor Receptor-3, Is Associated With Autosomal Dominant Milroy-Like Primary Lymphedema

(2013) Kristiana Gordon et al.   CIRCULATION RESEARCH

Advances in therapeutic interventions targeting the vascular and lymphatic endothelium in inflammatory bowel disease

(2013) Silvia D’Alessio et al.   CURRENT OPINION IN GASTROENTEROLOGY

Planar Cell Polarity Protein Celsr1 Regulates Endothelial Adherens Junctions and Directed Cell Rearrangements during Valve Morphogenesis

(2013) Florence Tatin et al.   DEVELOPMENTAL CELL

Apelin Inhibits Diet-Induced Obesity by Enhancing Lymphatic and Blood Vessel Integrity

(2013) M. Sawane et al.   DIABETES

Luminal Bacteria Recruit CD103+ Dendritic Cells into the Intestinal Epithelium to Sample Bacterial Antigens for Presentation

(2013) Julia Farache et al.   IMMUNITY

Platelets mediate lymphovenous hemostasis to maintain blood-lymphatic separation throughout life

(2013) Paul R. Hess et al.   JOURNAL OF CLINICAL INVESTIGATION

Lymphatic vasculature mediates macrophage reverse cholesterol transport in mice

(2013) Catherine Martel et al.   JOURNAL OF CLINICAL INVESTIGATION

Mechanisms for the prevention of vitamin E excess

(2013) Maret G. Traber   JOURNAL OF LIPID RESEARCH

Carotenoid metabolism in mammals, including man: formation, occurrence, and function of apocarotenoids

(2013) Abdulkerim Eroglu et al.   JOURNAL OF LIPID RESEARCH

Intestinal SR-BI does not impact cholesterol absorption or transintestinal cholesterol efflux in mice

(2013) Kanwardeep S. Bura et al.   JOURNAL OF LIPID RESEARCH

Permeability and contractile responses of collecting lymphatic vessels elicited by atrial and brain natriuretic peptides

(2013) Joshua P. Scallan et al.   JOURNAL OF PHYSIOLOGY-LONDON

Noonan syndrome

(2013) Amy E Roberts et al.   LANCET

EMILIN1/α9β1 Integrin Interaction Is Crucial in Lymphatic Valve Formation and Maintenance

(2013) Carla Danussi et al.   MOLECULAR AND CELLULAR BIOLOGY

Innate lymphoid cells regulate CD4+ T-cell responses to intestinal commensal bacteria

(2013) Matthew R. Hepworth et al.   NATURE

Demonstration of ATP-Dependent, Transcellular Transport of Lipid Across the Lymphatic Endothelium Using an In Vitro Model of the Lacteal

(2013) Alana L. Reed et al.   PHARMACEUTICAL RESEARCH

Anti-VEGF- and anti-VEGF receptor-induced vascular alteration in mouse healthy tissues

(2013) Y. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Plasticity of Button-Like Junctions in the Endothelium of Airway Lymphatics in Development and Inflammation

(2012) Li-Chin Yao et al.   AMERICAN JOURNAL OF PATHOLOGY

Involvement of the NO-cGMP-KATP channel pathway in the mesenteric lymphatic pump dysfunction observed in the guinea pig model of TNBS-induced ileitis

(2012) Ryan Mathias et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

3-D imaging and illustration of mouse intestinal neurovascular complex

(2012) Ya-Yuan Fu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

An Unexpected Role of Semaphorin3A–Neuropilin-1 Signaling in Lymphatic Vessel Maturation and Valve Formation

(2012) Giorgia Jurisic et al.   CIRCULATION RESEARCH

Semaphorin3A, Neuropilin-1, and PlexinA1 Are Required for Lymphatic Valve Formation

(2012) Karine Bouvrée et al.   CIRCULATION RESEARCH

lyve1 expression reveals novel lymphatic vessels and new mechanisms for lymphatic vessel development in zebrafish

(2012) K. S. Okuda et al.   DEVELOPMENT

Mechanotransduction, PROX1, and FOXC2 Cooperate to Control Connexin37 and Calcineurin during Lymphatic-Valve Formation

(2012) Amélie Sabine et al.   DEVELOPMENTAL CELL

Interleukin-22 Protects Intestinal Stem Cells from Immune-Mediated Tissue Damage and Regulates Sensitivity to Graft versus Host Disease

(2012) Alan M. Hanash et al.   IMMUNITY

Circulatory Antigen Processing by Mucosal Dendritic Cells Controls CD8+ T Cell Activation

(2012) Sun-Young Chang et al.   IMMUNITY

RASA1 maintains the lymphatic vasculature in a quiescent functional state in mice

(2012) Philip E. Lapinski et al.   JOURNAL OF CLINICAL INVESTIGATION

Isolated Tumor Cells in Regional Lymph Nodes as Relapse Predictors in Stage I and II Colorectal Cancer

(2012) Claudia Mescoli et al.   JOURNAL OF CLINICAL ONCOLOGY

Global, regional, and national causes of child mortality: an updated systematic analysis for 2010 with time trends since 2000

(2012) Li Liu et al.   LANCET

Analysis of Nerve Supply Pattern in Human Lymphatic Vessels of Young and Old Men

(2012) F. Mignini et al.   Lymphatic Research and Biology

Intestinal CD103− dendritic cells migrate in lymph and prime effector T cells

(2012) V Cerovic et al.   Mucosal Immunology

Oral tolerance to food protein

(2012) O Pabst et al.   Mucosal Immunology

Goblet cells deliver luminal antigen to CD103+ dendritic cells in the small intestine

(2012) Jeremiah R. McDole et al.   NATURE

Characteristics of Multi-Organ Lymphangiectasia Resulting from Temporal Deletion of Calcitonin Receptor-Like Receptor in Adult Mice

(2012) Samantha L. Hoopes et al.   PLoS One

Lymph node homing of T cells and dendritic cells via afferent lymphatics

(2012) Reinhold Förster et al.   TRENDS IN IMMUNOLOGY

Mesenchymal Cells of the Intestinal Lamina Propria

(2011) D.W. Powell et al.   Annual Review of Physiology

CCBE1 Is Essential for Mammalian Lymphatic Vascular Development and Enhances the Lymphangiogenic Effect of Vascular Endothelial Growth Factor-C In Vivo

(2011) Frank L. Bos et al.   CIRCULATION RESEARCH

Role of the lymphatic system in the pathogenesis of Crohnʼs disease

(2011) Pierre-Yves von der Weid et al.   CURRENT OPINION IN GASTROENTEROLOGY

Connexin37 and Connexin43 deficiencies in mice disrupt lymphatic valve development and result in lymphatic disorders including lymphedema and chylothorax

(2011) John D. Kanady et al.   DEVELOPMENTAL BIOLOGY

Pericytes: Developmental, Physiological, and Pathological Perspectives, Problems, and Promises

(2011) Annika Armulik et al.   DEVELOPMENTAL CELL

Mechanoinduction of lymph vessel expansion

(2011) Lara Planas-Paz et al.   EMBO JOURNAL

Mesenteric fat as a source of C reactive protein and as a target for bacterial translocation in Crohn's disease

(2011) Laurent Peyrin-Biroulet et al.   GUT

Lymphatic vascular morphogenesis in development, physiology, and disease

(2011) Stefan Schulte-Merker et al.   JOURNAL OF CELL BIOLOGY

Genes regulating lymphangiogenesis control venous valve formation and maintenance in mice

(2011) Eleni Bazigou et al.   JOURNAL OF CLINICAL INVESTIGATION

Molecular Detection of Tumor Cells in Regional Lymph Nodes Is Associated With Disease Recurrence and Poor Survival in Node-Negative Colorectal Cancer: A Systematic Review and Meta-Analysis

(2011) Nuh N. Rahbari et al.   JOURNAL OF CLINICAL ONCOLOGY

RORγt+ innate lymphoid cells regulate intestinal homeostasis by integrating negative signals from the symbiotic microbiota

(2011) Shinichiro Sawa et al.   NATURE IMMUNOLOGY

Epidemiology of cancer of the small intestine

(2011) Sai Yi Pan   World Journal of Gastrointestinal Oncology

Intestinal lymphangiectasia in adults

(2011) Hugh James Freeman   World Journal of Gastrointestinal Oncology

Review article: lymphatic system and associated adipose tissue in the development of inflammatory bowel disease

(2010) P.-Y. Von Der Weid et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Emerging roles of lymphatics in inflammatory bowel disease

(2010) J. Steven Alexander et al.   Annals of the New York Academy of Sciences

Lymphatic pump function in the inflamed gut

(2010) Pierre-Yves Von Der Weid et al.   Annals of the New York Academy of Sciences

The Biogenesis of Chylomicrons

(2010) Charles M. Mansbach et al.   Annual Review of Physiology

Novel function for blood platelets and podoplanin in developmental separation of blood and lymphatic circulation

(2010) P. Uhrin et al.   BLOOD

Platelets regulate lymphatic vascular development through CLEC-2-SLP-76 signaling

(2010) C. C. Bertozzi et al.   BLOOD

Homeostasis and Inflammation in the Intestine

(2010) Wendy S. Garrett et al.   CELL

Angptl4 Protects against Severe Proinflammatory Effects of Saturated Fat by Inhibiting Fatty Acid Uptake into Mesenteric Lymph Node Macrophages

(2010) Laeticia Lichtenstein et al.   Cell Metabolism

Regulation of Developmental Lymphangiogenesis by Syk+ Leukocytes

(2010) Ruben Böhmer et al.   DEVELOPMENTAL CELL

Primary Intestinal Lymphangiectasia: Four Case Reports and a Review of the Literature

(2010) Jie Wen et al.   DIGESTIVE DISEASES AND SCIENCES

Claudin-like protein 24 interacts with the VEGFR-2 and VEGFR-3 pathways and regulates lymphatic vessel development

(2010) P. Saharinen et al.   GENES & DEVELOPMENT

Essentialin VivoRoles of the C-type Lectin Receptor CLEC-2

(2010) Katsue Suzuki-Inoue et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tbx1 regulatesVegfr3and is required for lymphatic vessel development

(2010) Li Chen et al.   JOURNAL OF CELL BIOLOGY

Neuropilin-2 mediates VEGF-C–induced lymphatic sprouting together with VEGFR3

(2010) Yunling Xu et al.   JOURNAL OF CELL BIOLOGY

Activated regulatory T cells are the major T cell type emigrating from the skin during a cutaneous immune response in mice

(2010) Michio Tomura et al.   JOURNAL OF CLINICAL INVESTIGATION

Pathogenic Hantaviruses Direct the Adherence of Quiescent Platelets to Infected Endothelial Cells

(2010) I. N. Gavrilovskaya et al.   JOURNAL OF VIROLOGY

Colorectal cancer

(2010) David Cunningham et al.   LANCET

Subcapsular sinus macrophages prevent CNS invasion on peripheral infection with a neurotropic virus

(2010) Matteo Iannacone et al.   NATURE

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

(2010) Andre Franke et al.   NATURE GENETICS

The Mechanism of Lymphatic Access of Two Cholesteryl Ester Transfer Protein Inhibitors (CP524,515 and CP532,623) and Evaluation of Their Impact on Lymph Lipoprotein Profiles

(2010) Natalie L. Trevaskis et al.   PHARMACEUTICAL RESEARCH

Protein-Losing Enteropathy: Case Illustrations and Clinical Review

(2009) Sarah B Umar et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Intestinal lipid absorption

(2009) Jahangir Iqbal et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Liprin  1 is highly expressed in lymphatic vasculature and is important for lymphatic vessel integrity

(2009) C. Norrmen et al.   BLOOD

The effects of mechanical forces on intestinal physiology and pathology

(2009) Christopher P. Gayer et al.   CELLULAR SIGNALLING

Organ-specific lymphangiectasia, arrested lymphatic sprouting, and maturation defects resulting from gene-targeting of the PI3K regulatory isoforms p85α, p55α, and p50α

(2009) Carla Mouta-Bellum et al.   DEVELOPMENTAL DYNAMICS

Evidence for Medium Chain Triglycerides in the Treatment of Primary Intestinal Lymphangiectasia

(2009) A. P. Desai et al.   EUROPEAN JOURNAL OF PEDIATRIC SURGERY

The lymphatic system controls intestinal inflammation and inflammation-associated colon cancer through the chemokine decoy receptor D6

(2009) S. Vetrano et al.   GUT

Origin of the Lamina Propria Dendritic Cell Network

(2009) Milena Bogunovic et al.   IMMUNITY

Angiopoietin-2 in experimental colitis

(2009) Vijay C. Ganta et al.   INFLAMMATORY BOWEL DISEASES

FOXC2 controls formation and maturation of lymphatic collecting vessels through cooperation with NFATc1

(2009) Camilla Norrmén et al.   JOURNAL OF CELL BIOLOGY

Intestinal CD103+, but not CX3CR1+, antigen sampling cells migrate in lymph and serve classical dendritic cell functions

(2009) Olga Schulz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Recessive primary congenital lymphoedema caused by a VEGFR3 mutation

(2009) A Ghalamkarpour et al.   JOURNAL OF MEDICAL GENETICS

Mechanisms of lymphatic metastasis in human colorectal adenocarcinoma

(2009) Daniel Royston et al.   JOURNAL OF PATHOLOGY

Contractile Physiology of Lymphatics

(2009) David C. Zawieja   Lymphatic Research and Biology

The development of intestinal lymphoid tissues at the interface of self and microbiota

(2009) G Eberl et al.   Mucosal Immunology

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

(2009) Toshiro Sato et al.   NATURE

Mutations in CCBE1 cause generalized lymph vessel dysplasia in humans

(2009) Marielle Alders et al.   NATURE GENETICS

Control of vascular morphogenesis and homeostasis through the angiopoietin–Tie system

(2009) Hellmut G. Augustin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Stem Cells, Self-Renewal, and Differentiation in the Intestinal Epithelium

(2008) Laurens G. van der Flier et al.   Annual Review of Physiology

Organization and developmental aspects of lymphatic vessels

(2008) Osamu Ohtani et al.   ARCHIVES OF HISTOLOGY AND CYTOLOGY

Microbial Influences in Inflammatory Bowel Diseases

(2008) R. Balfour Sartor   GASTROENTEROLOGY

Chylomicrons promote intestinal absorption of lipopolysaccharides

(2008) Sarbani Ghoshal et al.   JOURNAL OF LIPID RESEARCH

Deletion of Vascular Endothelial Growth Factor C (VEGF-C) and VEGF-D Is Not Equivalent to VEGF Receptor 3 Deletion in Mouse Embryos

(2008) P. Haiko et al.   MOLECULAR AND CELLULAR BIOLOGY

A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity

(2008) Marina Cella et al.   NATURE

Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation

(2008) Tuomas Tammela et al.   NATURE

Rapid leukocyte migration by integrin-independent flowing and squeezing

(2008) Tim Lämmermann et al.   NATURE

Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease

(2008) Sakura Saburi et al.   NATURE GENETICS

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

(2008) Jeffrey C Barrett et al.   NATURE GENETICS

Primary intestinal lymphangiectasia (Waldmann's disease)

(2008) Stéphane Vignes et al.   Orphanet Journal of Rare Diseases

Why does the gut choose apolipoprotein B48 but not B100 for chylomicron formation?

(2007) Chun-Min Lo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY