Glyceride-Mimetic Prodrugs Incorporating Self-Immolative Spacers Promote Lymphatic Transport, Avoid First-Pass Metabolism, and Enhance Oral Bioavailability

Esterase-Sensitive Prodrugs with Tunable Release Rates and Direct Generation of Hydrogen Sulfide

(2016) Yueqin Zheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

DLL4 promotes continuous adult intestinal lacteal regeneration and dietary fat transport

(2015) Jeremiah Bernier-Latmani et al.   JOURNAL OF CLINICAL INVESTIGATION

From sewer to saviour — targeting the lymphatic system to promote drug exposure and activity

(2015) Natalie L. Trevaskis et al.   NATURE REVIEWS DRUG DISCOVERY

Targeted delivery of a model immunomodulator to the lymphatic system: Comparison of alkyl ester versus triglyceride mimetic lipid prodrug strategies

(2014) Sifei Han et al.   JOURNAL OF CONTROLLED RELEASE

Structure-based programming of lymph-node targeting in molecular vaccines

(2014) Haipeng Liu et al.   NATURE

The Impact of Lymphatic Transport on the Systemic Disposition of Lipophilic Drugs

(2013) Suzanne M. Caliph et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Trimethyl lock: a trigger for molecular release in chemistry, biology, and pharmacology

(2012) Michael N. Levine et al.   Chemical Science

The Biogenesis of Chylomicrons

(2010) Charles M. Mansbach et al.   Annual Review of Physiology

Targeted Drug Delivery to Lymphocytes: A Route to Site-Specific Immunomodulation?

(2010) Natalie L. Trevaskis et al.   MOLECULAR PHARMACEUTICS

A tissue-engineered model of the intestinal lacteal for evaluating lipid transport by lymphatics

(2009) J. Brandon Dixon et al.   BIOTECHNOLOGY AND BIOENGINEERING

The role of molecular physicochemical properties and apolipoproteins in association of drugs with triglyceride-rich lipoproteins: in-silico prediction of uptake by chylomicrons

(2009) Pavel Gershkovich et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY