Diverse Phytochemicals and Bioactivities in the Ancient Fruit and Modern Functional Food Pomegranate (Punica granatum)

Clustering according to urolithin metabotype explains the interindividual variability in the improvement of cardiovascular risk biomarkers in overweight-obese individuals consuming pomegranate: A randomized clinical trial

(2017) Antonio González-Sarrías et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Antiobesity Effects of Anthocyanins in Preclinical and Clinical Studies

(2017) Elena Azzini et al.   Oxidative Medicine and Cellular Longevity

Antiatherogenic effects of ellagic acid and urolithins in vitro

(2016) Laura Mele et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Effects of anthocyanins on the prevention and treatment of cancer

(2016) Bo-Wen Lin et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cardiovascular disease management through restrained inflammatory responses

(2016) Nasimudeen R. Jabir et al.   CURRENT PHARMACEUTICAL DESIGN

Methylated urolithin A, the modified ellagitannin-derived metabolite, suppresses cell viability of DU145 human prostate cancer cells via targeting miR-21

(2016) Benhong Zhou et al.   FOOD AND CHEMICAL TOXICOLOGY

Anthocyanins as inflammatory modulators and the role of the gut microbiota

(2016) Carina Almeida Morais et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Action mechanism and cardiovascular effect of anthocyanins: a systematic review of animal and human studies

(2016) Jordano Ferreira Reis et al.   Journal of Translational Medicine

Urolithin A suppresses the proliferation of endometrial cancer cells by mediating estrogen receptor-α-dependent gene expression

(2016) Wei Zhang et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Effects on Nitric Oxide Production of Urolithins, Gut-Derived Ellagitannin Metabolites, in Human Aortic Endothelial Cells

(2016) Valentina Spigoni et al.   MOLECULES

Punigratane, a novel pyrrolidine alkaloid from Punica granatum rind with putative efflux inhibition activity

(2016) Zumaana Rafiq et al.   NATURAL PRODUCT RESEARCH

Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents

(2016) Dongryeol Ryu et al.   NATURE MEDICINE

Anthocyanins in cardioprotection: A path through mitochondria

(2016) Julius Liobikas et al.   PHARMACOLOGICAL RESEARCH

Glucose ester enabled acylation in plant specialized metabolism

(2016) Alexander E. Wilson et al.   PHYTOCHEMISTRY REVIEWS

Effect of Aronia melanocarpa (Black Chokeberry) supplementation on the development of obesity in mice fed a high-fat diet

(2016) Jamie I. Baum et al.   Journal of Berry Research

Pomegranate’s Neuroprotective Effects against Alzheimer’s Disease Are Mediated by Urolithins, Its Ellagitannin-Gut Microbial Derived Metabolites

(2015) Tao Yuan et al.   ACS Chemical Neuroscience

Health benefits of anthocyanins and molecular mechanisms: Update from recent decade

(2015) Daotong Li et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Urolithin A causes p21 up-regulation in prostate cancer cells

(2015) Claudia Sánchez-González et al.   EUROPEAN JOURNAL OF NUTRITION

Cloning and expression of anthocyanin biosynthetic genes in red and white pomegranate

(2015) Xueqing Zhao et al.   JOURNAL OF PLANT RESEARCH

Cytochrome P450 1 family and cancers

(2015) Ryeo-Eun Go et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

The ellagitannin colonic metabolite urolithin D selectively inhibits EphA2 phosphorylation in prostate cancer cells

(2015) Carmine Giorgio et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Interindividual variability in the human metabolism of ellagic acid: Contribution of Gordonibacter to urolithin production

(2015) María Romo-Vaquero et al.   Journal of Functional Foods

Chemopreventive activity of ellagitannins and their derivatives from black raspberry seeds on HT-29 colon cancer cells

(2015) Hyunnho Cho et al.   Food & Function

A "White" Anthocyanin-less Pomegranate (Punica granatum L.) Caused by an Insertion in the Coding Region of the Leucoanthocyanidin Dioxygenase (LDOX; ANS) Gene

(2015) Zohar Ben-Simhon et al.   PLoS One

Ellagic Acid Metabolism by Human Gut Microbiota: Consistent Observation of Three Urolithin Phenotypes in Intervention Trials, Independent of Food Source, Age, and Health Status

(2014) Francisco A. Tomás-Barberán et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Influence of Gut Microbiota-Derived Ellagitanninsʼ Metabolites Urolithins on Pro-Inflammatory Activities of Human Neutrophils

(2014) Jakub Piwowarski et al.   PLANTA MEDICA

Wild Blueberries (Vaccinium myrtillus) Alleviate Inflammation and Hypertension Associated with Developing Obesity in Mice Fed with a High-Fat Diet

(2014) Otto T. Mykkänen et al.   PLoS One

Pomegranate phenolics inhibit formation of advanced glycation endproducts by scavenging reactive carbonyl species

(2014) Weixi Liu et al.   Food & Function

Walnut polyphenol metabolites, urolithins A and B, inhibit the expression of the prostate-specific antigen and the androgen receptor in prostate cancer cells

(2014) Claudia Sánchez-González et al.   Food & Function

A randomized, double-blind, placebo-controlled trial of the effect of dried purple carrot on body mass, lipids, blood pressure, body composition, and inflammatory markers in overweight and obese adults: The QUENCH Trial

(2013) Olivia R.L. Wright et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Wnt signaling in adult intestinal stem cells and cancer

(2013) Michaela Krausova et al.   CELLULAR SIGNALLING

Pomegranate Juice Metabolites, Ellagic Acid and Urolithin A, Synergistically Inhibit Androgen-Independent Prostate Cancer Cell Growth via Distinct Effects on Cell Cycle Control and Apoptosis

(2013) Roberto Vicinanza et al.   Evidence-based Complementary and Alternative Medicine

In vitro antioxidant and antiproliferative effects of ellagic acid and its colonic metabolite, urolithins, on human bladder cancer T24 cells

(2013) Zhenpeng Qiu et al.   FOOD AND CHEMICAL TOXICOLOGY

Ellagitannin oligomers and a neolignan from pomegranate arils and their inhibitory effects on the formation of advanced glycation end products

(2013) Hideyuki Ito et al.   FOOD CHEMISTRY

Contributions of phenolics and added vitamin C to the antioxidant capacity of pomegranate and grape juices: synergism and antagonism among constituents

(2013) Bradley W. Bolling et al.   INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY

Pomegranate and type 2 diabetes

(2013) Saleem Banihani et al.   NUTRITION RESEARCH

Extracts fromEpilobiumsp. Herbs, Their Components and Gut Microbiota Metabolites ofEpilobiumEllagitannins, Urolithins, Inhibit Hormone-Dependent Prostate Cancer Cells-(LNCaP) Proliferation and PSA Secretion

(2013) Magdalena Stolarczyk et al.   PHYTOTHERAPY RESEARCH

Clinical Evaluation of Blood Pressure Lowering, Endothelial Function Improving, Hypolipidemic and Anti-Inflammatory Effects of Pomegranate Juice in Hypertensive Subjects

(2013) Sedigheh Asgary et al.   PHYTOTHERAPY RESEARCH

New Phenolics from the Flowers of Punica granatum and Their In Vitro α-Glucosidase Inhibitory Activities

(2013) Tao Yuan et al.   PLANTA MEDICA

Pomegranate pericarp extract enhances the antibacterial activity of ciprofloxacin against extended-spectrum β-lactamase (ESBL) and metallo-β-lactamase (MBL) producing Gram-negative bacilli

(2012) Diganta Dey et al.   FOOD AND CHEMICAL TOXICOLOGY

Assay Dilution Factors Confound Measures of Total Antioxidant Capacity in Polyphenol-Rich Juices

(2012) Bradley W. Bolling et al.   JOURNAL OF FOOD SCIENCE

Ellagitannin metabolites, urolithin A glucuronide and its aglycone urolithin A, ameliorate TNF-α-induced inflammation and associated molecular markers in human aortic endothelial cells

(2012) Juan A. Giménez-Bastida et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Rapid and Comprehensive Evaluation of (Poly)phenolic Compounds in Pomegranate (Punica granatum L.) Juice by UHPLC-MSn

(2012) Pedro Mena et al.   MOLECULES

Antidiabetic Ellagitannins from Pomegranate Flowers: Inhibition of α-Glucosidase and Lipogenic Gene Expression

(2012) Tao Yuan et al.   ORGANIC LETTERS

Establishment of pomegranate (Punica granatum) hairy root cultures for genetic interrogation of the hydrolyzable tannin biosynthetic pathway

(2012) Nadia N. Ono et al.   PLANTA

Determination of Lignans in Edible and Nonedible Parts of Pomegranate (Punica granatum L.) and Products Derived Therefrom, Particularly Focusing on the Quantitation of Isolariciresinol Using HPLC-DAD-ESI/MSn

(2011) Ulrike Anna Fischer et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Pomegranate Ellagitannin-Derived Compounds Exhibit Antiproliferative and Antiaromatase Activity in Breast Cancer Cells In vitro

(2010) L. S. Adams et al.   Cancer Prevention Research

New flavonoids from Punica granatum flowers

(2010) Priyanka Bagri et al.   CHEMISTRY OF NATURAL COMPOUNDS

Colon Cancer Chemopreventive Activities of Pomegranate Ellagitannins and Urolithins

(2010) Sashi G. Kasimsetty et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Cyanidin-3-O-glucoside Protection against TNF-α-Induced Endothelial Dysfunction: Involvement of Nuclear Factor-κB Signaling

(2010) Antonio Speciale et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Effects of Pomegranate Chemical Constituents/Intestinal Microbial Metabolites on CYP1B1 in 22Rv1 Prostate Cancer Cells

(2009) Sashi G. Kasimsetty et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Antioxidant Capacity and Lipid Characterization of Six Georgia-Grown Pomegranate Cultivars

(2009) Garima Pande et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Interaction between Phenolics and Gut Microbiota: Role in Human Health

(2009) María V. Selma et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Effects of Fruit Ellagitannin Extracts, Ellagic Acid, and Their Colonic Metabolite, Urolithin A, on Wnt Signaling†

(2009) Meenakshi Sharma et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Antiplasmodial activity of Punica granatum L. fruit rind

(2009) Mario Dell’Agli et al.   JOURNAL OF ETHNOPHARMACOLOGY

sPhospholipase A2 is inhibited by anthocyanidins

(2009) Andrea Dreiseitel et al.   JOURNAL OF NEURAL TRANSMISSION

Dietary Blueberry Attenuates Whole-Body Insulin Resistance in High Fat-Fed Mice by Reducing Adipocyte Death and Its Inflammatory Sequelae

(2009) Jason DeFuria et al.   JOURNAL OF NUTRITION

Effect of pomegranate juice on Angiotensin II-induced hypertension in diabetic wistar rats

(2009) Mahalaxmi Mohan et al.   PHYTOTHERAPY RESEARCH

Medicinal Flowers. XXIII. New Taraxastane-Type Triterpene, Punicanolic Acid, with Tumor Necrosis Factor-α Inhibitory Activity from the Flowers of Punica granatum

(2008) Yuanyuan Xie et al.   CHEMICAL & PHARMACEUTICAL BULLETIN