New Insights into the Role of Autophagy in Tumor Immune Microenvironment

Inhibition of Autophagy by Deguelin Sensitizes Pancreatic Cancer Cells to Doxorubicin

(2017) Xiao Xu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Role of Autophagy and Apoptosis in Non-Small-Cell Lung Cancer

(2017) Guangbo Liu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Ginsenoside Rb2 Alleviates Hepatic Lipid Accumulation by Restoring Autophagy via Induction of Sirt1 and Activation of AMPK

(2017) Qi Huang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Inhibition of Autophagy Promotes Salinomycin-Induced Apoptosis via Reactive Oxygen Species-Mediated PI3K/AKT/mTOR and ERK/p38 MAPK-Dependent Signaling in Human Prostate Cancer Cells

(2017) Kwang-Youn Kim et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Chloroquine and hydroxychloroquine inhibit bladder cancer cell growth by targeting basal autophagy and enhancing apoptosis

(2017) Yi-Chia Lin et al.   KAOHSIUNG JOURNAL OF MEDICAL SCIENCES

Oxidative Stress and Autophagy in Metabolism and Longevity

(2017) Ajit Vikram et al.   Oxidative Medicine and Cellular Longevity

Single molecule force spectroscopy for in-situ probing oridonin inhibited ROS-mediated EGF-EGFR interactions in living KYSE-150 cells

(2017) Jiang Pi et al.   PHARMACOLOGICAL RESEARCH

Cancer immunotherapy: Breakthrough or “deja vu, all over again”?

(2017) Stewart Sell   TUMOR BIOLOGY

The oxido-metabolic driver ATF4 enhances temozolamide chemo-resistance in human gliomas

(2017) Daishi Chen et al.   Oncotarget

The role of autophagy in hepatocellular carcinoma: friend or foe

(2017) Lian Liu et al.   Oncotarget

DAMP-Induced Allograft and Tumor Rejection: The Circle Is Closing

(2016) W. G. Land et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Therapeutic interactions of autophagy with radiation and temozolomide in glioblastoma: evidence and issues to resolve

(2016) Michael I Koukourakis et al.   BRITISH JOURNAL OF CANCER

Inhibition of autophagy with chloroquine potentiates carfilzomib-induced apoptosis in myeloma cells in vitro and in vivo

(2016) Vidal Jarauta et al.   CANCER LETTERS

Cucurbitacin E induces caspase-dependent apoptosis and protective autophagy mediated by ROS in lung cancer cells

(2016) Guixin Ma et al.   CHEMICO-BIOLOGICAL INTERACTIONS

SIRT3 Silencing Sensitizes Breast Cancer Cells to Cytotoxic Treatments Through an Increment in ROS Production

(2016) Margalida Torrens-Mas et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Macrophage migration inhibitory factor induces autophagy to resist hypoxia/serum deprivation-induced apoptosis via the AMP-activated protein kinase/mammalian target of rapamycin signaling pathway

(2016) WENZHENG XIA et al.   Molecular Medicine Reports

Damage-associated molecular patterns in cancer: a double-edged sword

(2016) C Hernandez et al.   ONCOGENE

Thioredoxin Binding Protein-2 Regulates Autophagy of Human Lens Epithelial Cells under Oxidative Stress via Inhibition of Akt Phosphorylation

(2016) Jiaojie Zhou et al.   Oxidative Medicine and Cellular Longevity

The IL-1 cytokine family and its role in inflammation and fibrosis in the lung

(2016) L. A. Borthwick   Seminars in Immunopathology

IL-1 receptor antagonist ameliorates inflammasome-dependent inflammation in murine and human cystic fibrosis

(2016) Rossana G. Iannitti et al.   Nature Communications

The multifaceted role of autophagy in tumor evasion from immune surveillance

(2016) Bassam Janji et al.   Oncotarget

Interferon-related secretome from direct interaction between immune cells and tumor cells is required for upregulation of PD-L1 in tumor cells

(2016) Yuan-Qin Yang et al.   Protein & Cell

Blocking tumor growth by targeting autophagy and SQSTM1 in vivo

(2015) Huijun Wei et al.   Autophagy

Epidemiological-molecular evidence of metabolic reprogramming on proliferation, autophagy and cell signaling in pancreas cancer

(2015) Kjetil Søreide et al.   CANCER LETTERS

Signaling pathways and mechanisms of hypoxia-induced autophagy in the animal cells

(2015) Yungyun Fang et al.   CELL BIOLOGY INTERNATIONAL

Cell Death Conversion under Hypoxic Condition in Tumor Development and Therapy

(2015) Yu Qiu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Autophagy in DNA Damage Response

(2015) Piotr Czarny et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Role of Autophagy in Hepatocellular Carcinoma

(2015) Yoo Lee et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Selective Degradation of Synaptic Connexin 43 Protein by Hypoxia-induced Autophagy Impairs Natural Killer Cell-mediated Tumor Cell Killing

(2015) Andrés Tittarelli et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy and autophagy-related proteins in the immune system

(2015) Shusaku T Shibutani et al.   NATURE IMMUNOLOGY

Beclin 1 regulates growth factor receptor signaling in breast cancer

(2015) R A Rohatgi et al.   ONCOGENE

The critical role of quercetin in autophagy and apoptosis in HeLa cells

(2015) Yijun Wang et al.   TUMOR BIOLOGY

Truncating mutation in the autophagy gene UVRAG confers oncogenic properties and chemosensitivity in colorectal cancers

(2015) Shanshan He et al.   Nature Communications

Cross-presentation of antigens by dendritic cells: role of autophagy

(2015) Mrinmoy Das et al.   Oncotarget

DAMP production by human islets under low oxygen and nutrients in the presence or absence of an immunoisolating-capsule and necrostatin-1

(2015) Genaro A. Paredes-Juarez et al.   Scientific Reports

The role of autophagy induced by tumor microenvironment in different cells and stages of cancer

(2015) Xue Yang et al.   Cell and Bioscience

Interleukin-1β Promotes Ovarian Tumorigenesis through a p53/NF-κB-Mediated Inflammatory Response in Stromal Fibroblasts

(2015) Isaiah Gregory Schauer et al.   NEOPLASIA

Posttranslational modification of autophagy-related proteins in macroautophagy

(2014) Yangchun Xie et al.   Autophagy

Multi-drug resistance in cancer chemotherapeutics: Mechanisms and lab approaches

(2014) Qiong Wu et al.   CANCER LETTERS

BRCA1 deficiency induces protective autophagy to mitigate stress and provides a mechanism for BRCA1 haploinsufficiency in tumorigenesis

(2014) Maggie K.S. Tang et al.   CANCER LETTERS

Extracellular signal-regulated kinase, receptor interacting protein, and reactive oxygen species regulate shikonin-induced autophagy in human hepatocellular carcinoma

(2014) Ke Gong et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Beclin 1 Expression is Closely Linked to Colorectal Carcinogenesis and Distant Metastasis of Colorectal Carcinoma

(2014) Mei-Ying Zhang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Autophagic Cell Death and Cancer

(2014) Shigeomi Shimizu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cytotoxic Autophagy in Cancer Therapy

(2014) Khushboo Sharma et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Hypoxia-induced autophagy contributes to radioresistance via c-Jun-mediated Beclin1 expression in lung cancer cells

(2014) Yan-mei Zou et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

Mutational Landscape of the Essential Autophagy Gene BECN1 in Human Cancers

(2014) Saurabh V. Laddha et al.   MOLECULAR CANCER RESEARCH

Interferon-λ1 induces G1 phase cell cycle arrest and apoptosis in gastric carcinoma cells in vitro

(2014) ZHITAO GAO et al.   ONCOLOGY REPORTS

Honokiol activates reactive oxygen species-mediated cytoprotective autophagy in human prostate cancer cells

(2014) Eun-Ryeong Hahm et al.   PROSTATE

The Importance of Autophagy Regulation in Breast Cancer Development and Treatment

(2014) Joanna Magdalena Zarzynska   Biomed Research International

Tumor Suppression and Promotion by Autophagy

(2014) Yenniffer Ávalos et al.   Biomed Research International

Autophagy and genomic integrity

(2013) A T Vessoni et al.   CELL DEATH AND DIFFERENTIATION

RNA-Dependent Protein Kinase Is Essential for 2-Methoxyestradiol-Induced Autophagy in Osteosarcoma Cells

(2013) Caihong Yang et al.   PLoS One

Autophagy and chemotherapy resistance: a promising therapeutic target for cancer treatment

(2013) X Sui et al.   Cell Death & Disease

Cell-Mediated Autophagy Promotes Cancer Cell Survival

(2012) W. J. Buchser et al.   CANCER RESEARCH

Macrophage Migration Inhibitory Factor Induces Autophagy via Reactive Oxygen Species Generation

(2012) Yung-Chun Chuang et al.   PLoS One

Docosahexaenoic acid induces autophagy through p53/AMPK/mTOR signaling and promotes apoptosis in human cancer cells harboring wild-type p53

(2011) Kaipeng Jing et al.   Autophagy

A phase II study of neoadjuvant chemoradiotherapy with oxaliplatin and capecitabine for rectal cancer

(2011) Lin Zhao et al.   CANCER LETTERS

Autophagy-deficient mice develop multiple liver tumors

(2011) A. Takamura et al.   GENES & DEVELOPMENT

Autophagy in antigen-presenting cells results in presentation of citrullinated peptides to CD4 T cells

(2011) Jamie M. Ireland et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Autophagy-Mediated Dendritic Cell Activation Is Essential for Innate Cytokine Production and APC Function with Respiratory Syncytial Virus Responses

(2011) Susan Morris et al.   JOURNAL OF IMMUNOLOGY

Decreased expression of Beclin-1 and LC3 in human lung cancer

(2011) Zi-Feng Jiang et al.   MOLECULAR BIOLOGY REPORTS

The Receptor for Advanced Glycation End-Products (RAGE) Protects Pancreatic Tumor Cells Against Oxidative Injury

(2010) Rui Kang et al.   ANTIOXIDANTS & REDOX SIGNALING

Danger Signaling Protein HMGB1 Induces a Distinct Form of Cell Death Accompanied by Formation of Giant Mitochondria

(2010) G. Gdynia et al.   CANCER RESEARCH

Chaperone-mediated autophagy: machinery, regulation and biological consequences

(2010) Wenming Li et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Autophagy and Crohns Disease: At the Crossroads of Infection, Inflammation, Immunity, and Cancer

(2010) P. Brest et al.   CURRENT MOLECULAR MEDICINE

mTOR regulation of autophagy

(2010) Chang Hwa Jung et al.   FEBS LETTERS

Puromycin-sensitive aminopeptidase protects against aggregation-prone proteins via autophagy

(2010) Fiona M. Menzies et al.   HUMAN MOLECULAR GENETICS

Autophagy: cellular and molecular mechanisms

(2010) Danielle Glick et al.   JOURNAL OF PATHOLOGY

Autophagy-active beclin-1 correlates with favourable clinical outcome in non-Hodgkin lymphomas

(2010) Giuseppina Nicotra et al.   MODERN PATHOLOGY

The receptor for advanced glycation end products (RAGE) sustains autophagy and limits apoptosis, promoting pancreatic tumor cell survival

(2009) R Kang et al.   CELL DEATH AND DIFFERENTIATION

Hypoxia-induced autophagy: cell death or cell survival?

(2009) Nathalie M Mazure et al.   CURRENT OPINION IN CELL BIOLOGY

Mammalian autophagy: core molecular machinery and signaling regulation

(2009) Zhifen Yang et al.   CURRENT OPINION IN CELL BIOLOGY

ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery

(2009) Chang Hwa Jung et al.   MOLECULAR BIOLOGY OF THE CELL