Ginsenoside Rb2 Alleviates Hepatic Lipid Accumulation by Restoring Autophagy via Induction of Sirt1 and Activation of AMPK

Identification of natural products with neuronal and metabolic benefits through autophagy induction

(2016) Yuying Fan et al.   Autophagy

Ginsenoside Rg1 inhibits angiotensin II-induced podocyte autophagy via AMPK/mTOR/PI3K pathway

(2016) Nan Mao et al.   CELL BIOLOGY INTERNATIONAL

Ginsenosides from stems and leaves of ginseng prevent ethanol-induced lipid accumulation in human L02 hepatocytes

(2016) Chao-feng Hu et al.   Chinese Journal of Integrative Medicine

FNDC5 Alleviates Hepatosteatosis by Restoring AMPK/mTOR-Mediated Autophagy, Fatty Acid Oxidation, and Lipogenesis in Mice

(2016) Tong-Yan Liu et al.   DIABETES

Herbal medicines and nonalcoholic fatty liver disease

(2016) Hong Yao et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Ginsenoside compound K sensitizes human colon cancer cells to TRAIL-induced apoptosis via autophagy-dependent and -independent DR5 upregulation

(2016) Lei Chen et al.   Cell Death & Disease

Ginsenoside Rh2 inhibits hepatocellular carcinoma through β-catenin and autophagy

(2016) Zhiqing Yang et al.   Scientific Reports

Autophagy and Lipid Droplets in the Liver

(2015) Nuria Martinez-Lopez et al.   Annual Review of Nutrition

Ginsenoside Rg1 reduces aldosterone-induced autophagy via the AMPK/mTOR pathway in NRK-52E cells

(2015) LI WANG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

mTOR: a pharmacologic target for autophagy regulation

(2015) Young Chul Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

Insulin sensitivity improvement of fermented Korean Red Ginseng (Panax ginseng) mediated by insulin resistance hallmarks in old-aged ob/ob mice

(2015) Jeong-Mu Cheon et al.   Journal of Ginseng Research

Korean Red Ginseng attenuates ethanol-induced steatosis and oxidative stress via AMPK/Sirt1 activation

(2015) Jae Yun Han et al.   Journal of Ginseng Research

Metformin alleviates hepatosteatosis by restoring SIRT1-mediated autophagy induction via an AMP-activated protein kinase-independent pathway

(2014) Young Mi Song et al.   Autophagy

Inhibition of Autophagy via Activation of PI3K/Akt Pathway Contributes to the Protection of Ginsenoside Rb1 against Neuronal Death Caused by Ischemic Insults

(2014) Tianfei Luo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cinnamtannin D-1 Protects Pancreatic β-Cells from Palmitic Acid-Induced Apoptosis by Attenuating Oxidative Stress

(2014) Ting Wang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Epigallocatechin-3-Gallate (EGCG), a Green Tea Polyphenol, Stimulates Hepatic Autophagy and Lipid Clearance

(2014) Jin Zhou et al.   PLoS One

The Effect of Ginseng (The Genus Panax) on Glycemic Control: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials

(2014) Esra' Shishtar et al.   PLoS One

Impaired autophagic flux is associated with increased endoplasmic reticulum stress during the development of NAFLD

(2014) Á González-Rodríguez et al.   Cell Death & Disease

Yin and Yang of ginseng pharmacology: ginsenosides vs gintonin

(2013) Dong-soon Im et al.   ACTA PHARMACOLOGICA SINICA

Why should autophagic flux be assessed?

(2013) Xiao-jie Zhang et al.   ACTA PHARMACOLOGICA SINICA

Caffeine stimulates hepatic lipid metabolism by the autophagy-lysosomal pathway in mice

(2013) Rohit A. Sinha et al.   HEPATOLOGY

Progression of NAFLD to diabetes mellitus, cardiovascular disease or cirrhosis

(2013) Quentin M. Anstee et al.   Nature Reviews Gastroenterology & Hepatology

Autophagy, polyphenols and healthy ageing

(2012) Kathrin Pallauf et al.   AGEING RESEARCH REVIEWS

Thyroid hormone stimulates hepatic lipid catabolism via activation of autophagy

(2012) Rohit Anthony Sinha et al.   JOURNAL OF CLINICAL INVESTIGATION

Peripheral signalling involved in energy homeostasis control

(2012) Andoni Lancha et al.   NUTRITION RESEARCH REVIEWS

Molecular mechanisms and the role of saturated fatty acids in the progression of non-alcoholic fatty liver disease

(2012) Alexandra K. Leamy et al.   PROGRESS IN LIPID RESEARCH

AMP-activated protein kinase (AMPK) controls the aging process via an integrated signaling network

(2011) Antero Salminen et al.   AGEING RESEARCH REVIEWS

The antidiabetic effect of ginsenoside Rb2 via activation of AMPK

(2011) Kyoung-Tae Lee et al.   ARCHIVES OF PHARMACAL RESEARCH

Autophagy in the Cellular Energetic Balance

(2011) Rajat Singh et al.   Cell Metabolism

Pathology of the liver in obese and diabetic ob/ob and db/db mice fed a standard or high-calorie diet

(2011) Viviane Trak-Smayra et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

The role of lipid droplets in metabolic disease in rodents and humans

(2011) Andrew S. Greenberg et al.   JOURNAL OF CLINICAL INVESTIGATION

Defective Hepatic Autophagy in Obesity Promotes ER Stress and Causes Insulin Resistance

(2010) Ling Yang et al.   Cell Metabolism

Neuroprotective effect of ginsenoside Rb1 on glutamate-induced neurotoxicity: With emphasis on autophagy

(2010) Zhaoyao Chen et al.   NEUROSCIENCE LETTERS

Ginseng Compounds: An Update on their Molecular Mechanisms and Medical Applications

(2009) Jian-Ming Lu et al.   Current Vascular Pharmacology

Molecular mechanisms involved in NAFLD progression

(2009) Mariano Malaguarnera et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Autophagy regulates lipid metabolism

(2009) Rajat Singh et al.   NATURE

Botanical characteristics, pharmacological effects and medicinal components of KoreanPanax ginsengC A Meyer

(2008) Kwang-tae CHOI   ACTA PHARMACOLOGICA SINICA

Recent insights into hepatic lipid metabolism in non-alcoholic fatty liver disease (NAFLD)

(2008) G MUSSO et al.   PROGRESS IN LIPID RESEARCH