Inhibition of Autophagy by Deguelin Sensitizes Pancreatic Cancer Cells to Doxorubicin

Inhibition of autophagy by chloroquine induces apoptosis in primary effusion lymphoma in vitro and in vivo through induction of endoplasmic reticulum stress

(2016) Md. Masud Alam et al.   APOPTOSIS

Simultaneous inhibition of the ubiquitin-proteasome system and autophagy enhances apoptosis induced by ER stress aggravators in human pancreatic cancer cells

(2016) Xu Li et al.   Autophagy

Cancer statistics, 2016

(2016) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Inhibition of autophagy with chloroquine potentiates carfilzomib-induced apoptosis in myeloma cells in vitro and in vivo

(2016) Vidal Jarauta et al.   CANCER LETTERS

Deguelin Induces the Apoptosis of Lung Squamous Cell Carcinoma Cells through Regulating the Expression of Galectin-1

(2016) Bing Yan et al.   International Journal of Biological Sciences

The anticancer effect of chaetocin is enhanced by inhibition of autophagy

(2016) H-J Jung et al.   Cell Death & Disease

Deguelin inhibits proliferation and migration of human pancreatic cancer cells in vitro targeting hedgehog pathway

(2016) Wen Zheng et al.   Oncology Letters

Antitumor effect of the novel sphingosine kinase 2 inhibitor ABC294640 is enhanced by inhibition of autophagy and by sorafenib in human cholangiocarcinoma cells

(2016) Xiwei Ding et al.   Oncotarget

Enhanced mitochondrial glutamine anaplerosis suppresses pancreatic cancer growth through autophagy inhibition

(2016) Seung Min Jeong et al.   Scientific Reports

Synergistic antitumor activity of withaferin A combined with oxaliplatin triggers reactive oxygen species-mediated inactivation of the PI3K/AKT pathway in human pancreatic cancer cells

(2015) Xu Li et al.   CANCER LETTERS

Deguelin Analogue SH-1242 Inhibits Hsp90 Activity and Exerts Potent Anticancer Efficacy with Limited Neurotoxicity

(2015) S.-C. Lee et al.   CANCER RESEARCH

ATG14 promotes membrane tethering and fusion of autophagosomes to endolysosomes

(2015) Jiajie Diao et al.   NATURE

Knockdown of heme oxygenase-1 promotes apoptosis and autophagy and enhances the cytotoxicity of doxorubicin in breast cancer cells

(2015) XIAO-FENG ZHU et al.   Oncology Letters

20(S)-Ginsenoside Rg3 is a novel inhibitor of autophagy and sensitizes hepatocellular carcinoma to doxorubicin

(2015) Dong-Gun Kim et al.   Oncotarget

CYB5A and autophagy-mediated cell death in pancreatic cancer

(2014) Elisa Giovannetti et al.   Autophagy

Phosphoprotein of Human Parainfluenza Virus Type 3 Blocks Autophagosome-Lysosome Fusion to Increase Virus Production

(2014) Binbin Ding et al.   Cell Host & Microbe

Upregulation of autophagy by hypoxia-inducible factor-1α promotes EMT and metastatic ability of CD133+ pancreatic cancer stem-like cells during intermittent hypoxia

(2014) HAITAO ZHU et al.   ONCOLOGY REPORTS

Synergistic antitumor effects of combined deguelin and cisplatin treatment in gastric cancer cells

(2014) ZHENGGUANG LI et al.   Oncology Letters

A novel antitumor activity of deguelin targeting the insulin-like growth factor (IGF) receptor pathway via up-regulation of IGF-binding protein-3 expression in breast cancer

(2013) Young-Ah Suh et al.   CANCER LETTERS

Chloroquine in Cancer Therapy: A Double-Edged Sword of Autophagy

(2013) T. Kimura et al.   CANCER RESEARCH

Deguelin suppresses pancreatic tumor growth and metastasis by inhibiting epithelial-to-mesenchymal transition in an orthotopic model

(2012) S R Boreddy et al.   ONCOGENE

Induction of DNA damage by deguelin is mediated through reducing DNA repair genes in human non-small cell lung cancer NCI-H460 cells

(2012) BIN-CHUAN JI et al.   ONCOLOGY REPORTS

Pancreatic cancers require autophagy for tumor growth

(2011) S. Yang et al.   GENES & DEVELOPMENT

Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis

(2011) J. Y. Guo et al.   GENES & DEVELOPMENT

Anticancer efficacy of deguelin in human prostate cancer cells targeting glycogen synthase kinase-3 β/β-catenin pathway

(2011) Vijayalakshmi Thamilselvan et al.   INTERNATIONAL JOURNAL OF CANCER

Autophagy Suppresses Tumorigenesis through Elimination of p62

(2009) Robin Mathew et al.   CELL

The MIQE Guidelines: Minimum Information for Publication of Quantitative Real-Time PCR Experiments

(2009) S. A. Bustin et al.   CLINICAL CHEMISTRY