SIRT3 Silencing Sensitizes Breast Cancer Cells to Cytotoxic Treatments Through an Increment in ROS Production

Mitochondrial Sirt3 supports cell proliferation by regulating glutamine-dependent oxidation in renal cell carcinoma

(2016) Jieun Choi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Pro-Proliferative Function of Mitochondrial Sirtuin Deacetylase SIRT3 in Human Melanoma

(2016) Jasmine George et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Acetylation of MnSOD directs enzymatic activity responding to cellular nutrient status or oxidative stress

(2016) Ozkan Ozden et al.   Aging-US

UCP2 inhibition sensitizes breast cancer cells to therapeutic agents by increasing oxidative stress

(2015) Daniel Gabriel Pons et al.   FREE RADICAL BIOLOGY AND MEDICINE

The presence of Estrogen Receptor β modulates the response of breast cancer cells to therapeutic agents

(2015) Daniel Gabriel Pons et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Interplay between ROS and autophagy in cancer cells, from tumor initiation to cancer therapy

(2015) Laura Poillet-Perez et al.   Redox Biology

SIRT3 Enhances Glycolysis and Proliferation in SIRT3-Expressing Gastric Cancer Cells

(2015) Yang Cui et al.   PLoS One

The SIRT 3 Expression Profile is Associated with Pathological and Clinical Outcomes in Human Breast Cancer Patients

(2014) Shaozhong He et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Phytoestrogens and Mitochondrial Biogenesis in Breast Cancer. Influence of Estrogen Receptors Ratio

(2014) Pilar Roca et al.   CURRENT PHARMACEUTICAL DESIGN

Decreased mitochondrial SIRT3 expression is a potential molecular biomarker associated with poor outcome in breast cancer

(2014) Mohamed Mokhtar Desouki et al.   HUMAN PATHOLOGY

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

(2014) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Sirtuin-3 (SIRT3), a therapeutic target with oncogenic and tumor-suppressive function in cancer

(2014) Y Chen et al.   Cell Death & Disease

The Importance of Autophagy Regulation in Breast Cancer Development and Treatment

(2014) Joanna Magdalena Zarzynska   Biomed Research International

Identification of Sirtuin 3, a mitochondrial protein deacetylase, as a new contributor to tamoxifen resistance in breast cancer cells

(2013) Li Zhang et al.   BIOCHEMICAL PHARMACOLOGY

SIRT3 deacetylates FOXO3 to protect mitochondria against oxidative damage

(2013) Anne H.H. Tseng et al.   FREE RADICAL BIOLOGY AND MEDICINE

SirT3 Regulates the Mitochondrial Unfolded Protein Response

(2013) L. Papa et al.   MOLECULAR AND CELLULAR BIOLOGY

Cisplatin Induces a Mitochondrial-ROS Response That Contributes to Cytotoxicity Depending on Mitochondrial Redox Status and Bioenergetic Functions

(2013) Rossella Marullo et al.   PLoS One

Oroxylin A induces dissociation of hexokinase II from the mitochondria and inhibits glycolysis by SIRT3-mediated deacetylation of cyclophilin D in breast carcinoma

(2013) L Wei et al.   Cell Death & Disease

UCP2 inhibition triggers ROS-dependent nuclear translocation of GAPDH and autophagic cell death in pancreatic adenocarcinoma cells

(2012) Ilaria Dando et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The descriptive epidemiology of female breast cancer: An international comparison of screening, incidence, survival and mortality

(2012) Danny R. Youlden et al.   Cancer Epidemiology

The Effects of 17β-estradiol on Mitochondrial Biogenesis and Function in Breast Cancer Cell Lines are Dependent on the ERα/ERβ Ratio

(2012) Jorge Sastre-Serra et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

SIRT3 regulation of mitochondrial oxidative stress

(2012) Alexandra S. Bause et al.   EXPERIMENTAL GERONTOLOGY

Reactive oxygen species regulation of autophagy in cancer: Implications for cancer treatment

(2012) Lin Li et al.   FREE RADICAL BIOLOGY AND MEDICINE

The ERalpha/ERbeta ratio determines oxidative stress in breast cancer cell lines in response to 17Beta-estradiol

(2012) Mercedes Nadal-Serrano et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

ROS, autophagy, mitochondria and cancer: Ras, the hidden master?

(2012) Gregory L. Bellot et al.   MITOCHONDRION

Tamoxifen regulates cell fate through mitochondrial estrogen receptor beta in breast cancer

(2012) M Razandi et al.   ONCOGENE

Metabolic regulation by SIRT3: implications for tumorigenesis

(2012) Lydia W.S. Finley et al.   TRENDS IN MOLECULAR MEDICINE

Mitochondrial Metabolism, Sirtuins, and Aging

(2012) M. N. Sack et al.   Cold Spring Harbor Perspectives in Biology

Radical Decisions in Cancer: Redox Control of Cell Growth and Death

(2012) Rosa M. Sainz et al.   Cancers

Tumour suppressor SIRT3 deacetylates and activates manganese superoxide dismutase to scavenge ROS

(2011) Yaohui Chen et al.   EMBO REPORTS

Autophagy and endocrine resistance in breast cancer

(2011) Katherine L Cook et al.   Expert Review of Anticancer Therapy

Sirt3, Mitochondrial ROS, Ageing, and Carcinogenesis

(2011) Seong-Hoon Park et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Sirtuin-3 (SIRT3), a novel potential therapeutic target for oral cancer

(2010) Turki Y. Alhazzazi et al.   CANCER

SIRT3 Is a Mitochondria-Localized Tumor Suppressor Required for Maintenance of Mitochondrial Integrity and Metabolism during Stress

(2010) Hyun-Seok Kim et al.   CANCER CELL

Regulation of autophagy by ROS: physiology and pathology

(2010) Ruth Scherz-Shouval et al.   TRENDS IN BIOCHEMICAL SCIENCES

An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients

(2009) Balazs Györffy et al.   BREAST CANCER RESEARCH AND TREATMENT