Exosomes: From Garbage Bins to Promising Therapeutic Targets

Exosomes: Fundamental Biology and Roles in Cardiovascular Physiology

(2016) Ahmed Ibrahim et al.   Annual Review of Physiology

Y-box protein 1 is required to sort microRNAs into exosomes in cells and in a cell-free reaction

(2016) Matthew J Shurtleff et al.   eLife

Long non-coding RNAs harboring miRNA seed regions are enriched in prostate cancer exosomes

(2016) Alireza Ahadi et al.   Scientific Reports

Syntenin and syndecan in the biogenesis of exosomes

(2015) Véronique Friand et al.   BIOLOGY OF THE CELL

Exosomal microRNA in serum is a novel biomarker of recurrence in human colorectal cancer

(2015) T Matsumura et al.   BRITISH JOURNAL OF CANCER

Exosomes as nanocarriers for immunotherapy of cancer and inflammatory diseases

(2015) Thanh-Huyen Tran et al.   CLINICAL IMMUNOLOGY

Exosomal miR-1290 and miR-375 as Prognostic Markers in Castration-resistant Prostate Cancer

(2015) Xiaoyi Huang et al.   EUROPEAN UROLOGY

Exosome Delivered Anticancer Drugs Across the Blood-Brain Barrier for Brain Cancer Therapy in Danio Rerio

(2015) Tianzhi Yang et al.   PHARMACEUTICAL RESEARCH

Exosome and Exosomal MicroRNA: Trafficking, Sorting, and Function

(2015) Jian Zhang et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Increased serum levels of circulating exosomal microRNA-373 in receptor-negative breast cancer patients

(2015) Corinna Eichelser et al.   Oncotarget

CD44v6 Dependence of Premetastatic Niche Preparation by Exosomes

(2015) Thorsten Jung et al.   NEOPLASIA

Exosomal Tumor MicroRNA Modulates Premetastatic Organ Cells

(2015) Sanyukta Rana et al.   NEOPLASIA

Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles

(2014) Marina Colombo et al.   Annual Review of Cell and Developmental Biology

Exosomal miR-135b shed from hypoxic multiple myeloma cells enhances angiogenesis by targeting factor-inhibiting HIF-1

(2014) T. Umezu et al.   BLOOD

Cancer-Secreted miR-105 Destroys Vascular Endothelial Barriers to Promote Metastasis

(2014) Weiying Zhou et al.   CANCER CELL

Cancer Exosomes Perform Cell-Independent MicroRNA Biogenesis and Promote Tumorigenesis

(2014) Sonia A. Melo et al.   CANCER CELL

Cellular Disposal of miR23b by RAB27-Dependent Exosome Release Is Linked to Acquisition of Metastatic Properties

(2014) M. S. Ostenfeld et al.   CANCER RESEARCH

Long non-coding RNAs with low expression levels in cells are enriched in secreted exosomes

(2014) Ugur Gezer et al.   CELL BIOLOGY INTERNATIONAL

Double-stranded DNA in exosomes: a novel biomarker in cancer detection

(2014) Basant Kumar Thakur et al.   CELL RESEARCH

Different exosome cargo from plasma/bronchoalveolar lavage in non-small-cell lung cancer

(2014) Marta Rodríguez et al.   GENES CHROMOSOMES & CANCER

Identification of Double-stranded Genomic DNA Spanning All Chromosomes with MutatedKRASandp53DNA in the Serum Exosomes of Patients with Pancreatic Cancer

(2014) Christoph Kahlert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exosome Uptake through Clathrin-mediated Endocytosis and Macropinocytosis and Mediating miR-21 Delivery

(2014) Tian Tian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human Tumor-Derived Exosomes Down-Modulate NKG2D Expression

(2014) A. Clayton et al.   JOURNAL OF IMMUNOLOGY

Dendritic Cell-Derived Exosomes as Immunotherapies in the Fight against Cancer

(2014) J. M. Pitt et al.   JOURNAL OF IMMUNOLOGY

Combined detection of serum exosomal miR-21 and HOTAIR as diagnostic and prognostic biomarkers for laryngeal squamous cell carcinoma

(2014) Jingting Wang et al.   MEDICAL ONCOLOGY

Activity-associated miRNA are packaged in Map1b-enriched exosomes released from depolarized neurons

(2014) Belinda J. Goldie et al.   NUCLEIC ACIDS RESEARCH

Exosome Release and Low pH Belong to a Framework of Resistance of Human Melanoma Cells to Cisplatin

(2014) Cristina Federici et al.   PLoS One

Cancer exosomes and NKG2D receptor–ligand interactions: Impairing NKG2D-mediated cytotoxicity and anti-tumour immune surveillance

(2014) Lucia Mincheva-Nilsson et al.   SEMINARS IN CANCER BIOLOGY

Plasma long noncoding RNA protected by exosomes as a potential stable biomarker for gastric cancer

(2014) Qier Li et al.   TUMOR BIOLOGY

Macrophage immunomodulation by breast cancer-derived exosomes requires Toll-like receptor 2-mediated activation of NF-κB

(2014) Amy Chow et al.   Scientific Reports

Extracellular vesicle-mediated transfer of long non-coding RNA ROR modulates chemosensitivity in human hepatocellular cancer

(2014) Kenji Takahashi et al.   FEBS Open Bio

Cardiac myocyte exosomes: stability, HSP60, and proteomics

(2013) Z. A. Malik et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Tumor cell-derived exosome-targeted dendritic cells stimulate stronger CD8+ CTL responses and antitumor immunities

(2013) Ye Yao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Exosomes as new vesicular lipid transporters involved in cell–cell communication and various pathophysiologies

(2013) Michel Record et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

A doxorubicin delivery platform using engineered natural membrane vesicle exosomes for targeted tumor therapy

(2013) Yanhua Tian et al.   BIOMATERIALS

Exosomes in cancer development, metastasis, and drug resistance: a comprehensive review

(2013) Asfar S. Azmi et al.   CANCER AND METASTASIS REVIEWS

Tetraspanin protein CD9 interacts with metalloprotease CD10 and enhances its release via exosomes

(2013) Dmitriy Mazurov et al.   FEBS Journal

Rab27 GTPases Distribute Extracellular Nanomaps for Invasive Growth and Metastasis: Implications for Prognosis and Treatment

(2013) An Hendrix et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Exosome Uptake Depends on ERK1/2-Heat Shock Protein 27 Signaling and Lipid Raft-mediated Endocytosis Negatively Regulated by Caveolin-1

(2013) Katrin J. Svensson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heparanase Regulates Secretion, Composition, and Function of Tumor Cell-derived Exosomes

(2013) Camilla A. Thompson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neutral Sphingomyelinase 2 (nSMase2)-dependent Exosomal Transfer of Angiogenic MicroRNAs Regulate Cancer Cell Metastasis

(2013) Nobuyoshi Kosaka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Body Fluid Exosomes Promote Secretion of Inflammatory Cytokines in Monocytic Cells via Toll-like Receptor Signaling

(2013) Niko P. Bretz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of Pancreatic Cancer-derived Exosomes in Salivary Biomarker Development

(2013) Chang Lau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exosomes Derived from Hypoxic Leukemia Cells Enhance Tube Formation in Endothelial Cells

(2013) Hiroko Tadokoro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Intracellular Interactome of Tetraspanin-enriched Microdomains Reveals Their Function as Sorting Machineries toward Exosomes

(2013) Daniel Perez-Hernandez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Extracellular vesicles: Exosomes, microvesicles, and friends

(2013) Graça Raposo et al.   JOURNAL OF CELL BIOLOGY

Analysis of ESCRT functions in exosome biogenesis, composition and secretion highlights the heterogeneity of extracellular vesicles

(2013) Marina Colombo et al.   JOURNAL OF CELL SCIENCE

Exosomes in the pathogenesis, diagnostics and therapeutics of liver diseases

(2013) Anatoliy I. Masyuk et al.   JOURNAL OF HEPATOLOGY

Heparin blocks transfer of extracellular vesicles between donor and recipient cells

(2013) Nadia A. Atai et al.   JOURNAL OF NEURO-ONCOLOGY

microRNAs Derived from Circulating Exosomes as Noninvasive Biomarkers for Screening and Diagnosing Lung Cancer

(2013) Riccardo Cazzoli et al.   Journal of Thoracic Oncology

Microparticles in Health and Disease

(2013) J.M. Herring et al.   JOURNAL OF VETERINARY INTERNAL MEDICINE

Mutation of SIMPLE in Charcot–Marie–Tooth 1C alters production of exosomes

(2013) Hong Zhu et al.   MOLECULAR BIOLOGY OF THE CELL

Microenvironmental regulation of tumor progression and metastasis

(2013) Daniela F Quail et al.   NATURE MEDICINE

Cancer cell exosomes depend on cell-surface heparan sulfate proteoglycans for their internalization and functional activity

(2013) H. C. Christianson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development

(2013) P. Kucharzewska et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A new role for microRNAs, as ligands of Toll-like receptors

(2013) Muller Fabbri et al.   RNA Biology

Ongoing activation of sphingosine 1-phosphate receptors mediates maturation of exosomal multivesicular endosomes

(2013) Taketoshi Kajimoto et al.   Nature Communications

Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specific motifs

(2013) Carolina Villarroya-Beltri et al.   Nature Communications

Exosome Secretion Is Enhanced by Invadopodia and Drives Invasive Behavior

(2013) Daisuke Hoshino et al.   Cell Reports

Delivery of Functional Anti-miR-9 by Mesenchymal Stem Cell–derived Exosomes to Glioblastoma Multiforme Cells Conferred Chemosensitivity

(2013) Jessian L Munoz et al.   Molecular Therapy-Nucleic Acids

Characterization of RNA in exosomes secreted by human breast cancer cell lines using next-generation sequencing

(2013) Piroon Jenjaroenpun et al.   PeerJ

Exosomes for targeted siRNA delivery across biological barriers

(2012) Samir EL Andaloussi et al.   ADVANCED DRUG DELIVERY REVIEWS

Extracellular vesicles - vehicles that spread cancer genes

(2012) Janusz Rak et al.   BIOESSAYS

Exosomes for drug delivery — a novel application for the mesenchymal stem cell

(2012) Ruenn Chai Lai et al.   BIOTECHNOLOGY ADVANCES

Hypoxic enhancement of exosome release by breast cancer cells

(2012) Hamish W King et al.   BMC CANCER

Selective extracellular vesicle-mediated export of an overlapping set of microRNAs from multiple cell types

(2012) Jasenka Guduric-Fuchs et al.   BMC GENOMICS

Rab27a Supports Exosome-Dependent and -Independent Mechanisms That Modify the Tumor Microenvironment and Can Promote Tumor Progression

(2012) A. Bobrie et al.   CANCER RESEARCH

Lipid-based carriers of microRNAs and intercellular communication

(2012) Kasey C. Vickers et al.   CURRENT OPINION IN LIPIDOLOGY

Doxorubicin: an update on anticancer molecular action, toxicity and novel drug delivery systems

(2012) Oktay Tacar et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

TGF- 1-Containing Exosomes from Injured Epithelial Cells Activate Fibroblasts to Initiate Tissue Regenerative Responses and Fibrosis

(2012) F. T. Borges et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Exosome removal as a therapeutic adjuvant in cancer

(2012) Annette M Marleau et al.   Journal of Translational Medicine

Microparticle conferred microRNA profiles - implications in the transfer and dominance of cancer traits

(2012) Ritu Jaiswal et al.   Molecular Cancer

Systemically Injected Exosomes Targeted to EGFR Deliver Antitumor MicroRNA to Breast Cancer Cells

(2012) Shin-ichiro Ohno et al.   MOLECULAR THERAPY

Active Wnt proteins are secreted on exosomes

(2012) Julia Christina Gross et al.   NATURE CELL BIOLOGY

Syndecan–syntenin–ALIX regulates the biogenesis of exosomes

(2012) Maria Francesca Baietti et al.   NATURE CELL BIOLOGY

Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

(2012) Héctor Peinado et al.   NATURE MEDICINE

Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells

(2012) Shayne A. Bellingham et al.   NUCLEIC ACIDS RESEARCH

Plasma exosomes can deliver exogenous short interfering RNA to monocytes and lymphocytes

(2012) Jessica Wahlgren et al.   NUCLEIC ACIDS RESEARCH

RhoA triggers a specific signaling pathway that generates transforming microvesicles in cancer cells

(2012) B Li et al.   ONCOGENE

The Majority of MicroRNAs Detectable in Serum and Saliva Is Concentrated in Exosomes

(2012) Alessia Gallo et al.   PLoS One

Lactation-Related MicroRNA Expression Profiles of Porcine Breast Milk Exosomes

(2012) Yiren Gu et al.   PLoS One

Formation and release of arrestin domain-containing protein 1-mediated microvesicles (ARMMs) at plasma membrane by recruitment of TSG101 protein

(2012) J. F. Nabhan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response

(2012) M. Fabbri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Emerging Role of Neuronal Exosomes in the Central Nervous System

(2012) Mathilde Chivet et al.   Frontiers in Physiology

Exosomes: Vehicles for the Transfer of Toxic Proteins Associated with Neurodegenerative Diseases?

(2012) Shayne A. Bellingham et al.   Frontiers in Physiology

Multivesicular Body Morphogenesis

(2011) Phyllis I. Hanson et al.   Annual Review of Cell and Developmental Biology

Interaction and uptake of exosomes by ovarian cancer cells

(2011) Cristina Escrevente et al.   BMC CANCER

Exosomes Released by Melanoma Cells Prepare Sentinel Lymph Nodes for Tumor Metastasis

(2011) J. L. Hood et al.   CANCER RESEARCH

Diacylglycerol kinase α regulates the formation and polarisation of mature multivesicular bodies involved in the secretion of Fas ligand-containing exosomes in T lymphocytes

(2011) R Alonso et al.   CELL DEATH AND DIFFERENTIATION

The Roles of Tumor-Derived Exosomes in Cancer Pathogenesis

(2011) Chenjie Yang et al.   Clinical & Developmental Immunology

MVB vesicle formation: ESCRT-dependent, ESCRT-independent and everything in between

(2011) Markus Babst   CURRENT OPINION IN CELL BIOLOGY

The Tetraspanin CD63 Regulates ESCRT-Independent and -Dependent Endosomal Sorting during Melanogenesis

(2011) Guillaume van Niel et al.   DEVELOPMENTAL CELL

Analysis of exosome release and its prognostic value in human colorectal cancer

(2011) J. Silva et al.   GENES CHROMOSOMES & CANCER

Hepatic cell-to-cell transmission of small silencing RNA can extend the therapeutic reach of RNA interference (RNAi)

(2011) Qiuwei Pan et al.   GUT

Intercellular nanovesicle-mediated microRNA transfer: A mechanism of environmental modulation of hepatocellular cancer cell growth

(2011) Takayuki Kogure et al.   HEPATOLOGY

Selective transfer of exosomes from oligodendrocytes to microglia by macropinocytosis

(2011) D. Fitzner et al.   JOURNAL OF CELL SCIENCE

Exosome-loaded dendritic cells elicit tumor-specific CD8+ cytotoxic T cells in patients with glioma

(2011) Ning Bu et al.   JOURNAL OF NEURO-ONCOLOGY

Pivotal role of paracrine effects in stem cell therapies in regenerative medicine: can we translate stem cell-secreted paracrine factors and microvesicles into better therapeutic strategies?

(2011) M Z Ratajczak et al.   LEUKEMIA

Treatment of Brain Inflammatory Diseases by Delivering Exosome Encapsulated Anti-inflammatory Drugs From the Nasal Region to the Brain

(2011) Xiaoying Zhuang et al.   MOLECULAR THERAPY

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

(2011) Lydia Alvarez-Erviti et al.   NATURE BIOTECHNOLOGY

ExoCarta 2012: database of exosomal proteins, RNA and lipids

(2011) S. Mathivanan et al.   NUCLEIC ACIDS RESEARCH

Exosomal evasion of humoral immunotherapy in aggressive B-cell lymphoma modulated by ATP-binding cassette transporter A3

(2011) T. Aung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mesenchymal stem cell exosome: a novel stem cell-based therapy for cardiovascular disease

(2011) Ruenn Chai Lai et al.   Regenerative Medicine

Exosome Secretion: Molecular Mechanisms and Roles in Immune Responses

(2011) Angélique Bobrie et al.   TRAFFIC

Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells

(2011) María Mittelbrunn et al.   Nature Communications

Exosome secretion of dendritic cells is regulated by Hrs, an ESCRT-0 protein

(2010) Keiichi Tamai et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomes

(2010) H. Sheldon et al.   BLOOD

Secretion of extracellular hsp90α via exosomes increases cancer cell motility: a role for plasminogen activation

(2010) Jessica McCready et al.   BMC CANCER

Relevance of circulating tumor cells, extracellular nucleic acids, and exosomes in breast cancer

(2010) Anne M. Friel et al.   BREAST CANCER RESEARCH AND TREATMENT

Dendritic Cell-Derived Exosomes for Cancer Immunotherapy: What's Next?

(2010) S. Viaud et al.   CANCER RESEARCH

Cell Surface Tetraspanin Tspan8 Contributes to Molecular Pathways of Exosome-Induced Endothelial Cell Activation

(2010) I. Nazarenko et al.   CANCER RESEARCH

Native IL-32 is released from intestinal epithelial cells via a non-classical secretory pathway as a membrane-associated protein

(2010) Haruki Hasegawa et al.   CYTOKINE

Activation-induced internalization differs for the tetraspanins CD9 and Tspan8: Impact on tumor cell motility

(2010) Sanyukta Rana et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Regulation of exosome secretion by Rab35 and its GTPase-activating proteins TBC1D10A–C

(2010) Chieh Hsu et al.   JOURNAL OF CELL BIOLOGY

Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells

(2010) Fanny Chalmin et al.   JOURNAL OF CLINICAL INVESTIGATION

Exosomes account for vesicle-mediated transcellular transport of activatable phospholipases and prostaglandins

(2010) Caroline Subra et al.   JOURNAL OF LIPID RESEARCH

Hypoxic Tumor Cell Modulates Its Microenvironment to Enhance Angiogenic and Metastatic Potential by Secretion of Proteins and Exosomes

(2010) Jung Eun Park et al.   MOLECULAR & CELLULAR PROTEOMICS

A Novel Nanoparticle Drug Delivery System: The Anti-inflammatory Activity of Curcumin Is Enhanced When Encapsulated in Exosomes

(2010) Dongmei Sun et al.   MOLECULAR THERAPY

Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line

(2010) Keiichi Ohshima et al.   PLoS One

Selective Release of MicroRNA Species from Normal and Malignant Mammary Epithelial Cells

(2010) Lucy Pigati et al.   PLoS One

Exosomes: immune properties and potential clinical implementations

(2010) Nathalie Chaput et al.   Seminars in Immunopathology

Cellular Internalization of Exosomes Occurs Through Phagocytosis

(2010) Du Feng et al.   TRAFFIC

TI-VAMP/VAMP7 and VAMP3/cellubrevin: two v-SNARE proteins involved in specific steps of the autophagy/multivesicular body pathways

(2009) Claudio Marcelo Fader et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Claudin-containing exosomes in the peripheral circulation of women with ovarian cancer

(2009) Jianghong Li et al.   BMC CANCER

Tumor-derived microvesicles modulate the establishment of metastatic melanoma in a phosphatidylserine-dependent manner

(2009) Luize G. Lima et al.   CANCER LETTERS

Exosomal MicroRNA: A Diagnostic Marker for Lung Cancer

(2009) Guilherme Rabinowits et al.   Clinical Lung Cancer

ARF6-Regulated Shedding of Tumor Cell-Derived Plasma Membrane Microvesicles

(2009) Vandhana Muralidharan-Chari et al.   CURRENT BIOLOGY

Exosomes in Tumour Immunity

(2009) Aled Clayton et al.   Current Oncology

Acid sphingomyelinase activity triggers microparticle release from glial cells

(2009) Fabio Bianco et al.   EMBO JOURNAL

Exosomes: proteomic insights and diagnostic potential

(2009) Richard J Simpson et al.   Expert Review of Proteomics

Microenvironmental pH Is a Key Factor for Exosome Traffic in Tumor Cells

(2009) Isabella Parolini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human liver stem cell-derived microvesicles accelerate hepatic regeneration in hepatectomized rats

(2009) M. B. Herrera et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Tumor-Derived Microvesicles Promote Regulatory T Cell Expansion and Induce Apoptosis in Tumor-Reactive Activated CD8+ T Lymphocytes

(2009) E. U. Wieckowski et al.   JOURNAL OF IMMUNOLOGY

Paracrine induction of endothelium by tumor exosomes

(2009) Joshua L Hood et al.   LABORATORY INVESTIGATION

The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins

(2009) Camilla Raiborg et al.   NATURE

Rab27a and Rab27b control different steps of the exosome secretion pathway

(2009) Matias Ostrowski et al.   NATURE CELL BIOLOGY

Membrane Fusion: Grappling with SNARE and SM Proteins

(2009) T. C. Sudhof et al.   SCIENCE

Multivesicular Endosome Biogenesis in the Absence of ESCRTs

(2009) Susanne Stuffers et al.   TRAFFIC

Blood diffusion and Th1-suppressive effects of galectin-9-containing exosomes released by Epstein-Barr virus-infected nasopharyngeal carcinoma cells

(2008) J. Klibi et al.   BLOOD

Exosome secretion, including the DNA damage-induced p53-dependent secretory pathway, is severely compromised in TSAP6/Steap3-null mice

(2008) A Lespagnol et al.   CELL DEATH AND DIFFERENTIATION

MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer

(2008) Douglas D. Taylor et al.   GYNECOLOGIC ONCOLOGY

Induction of myeloid-derived suppressor cells by tumor exosomes

(2008) Xiaoyu Xiang et al.   INTERNATIONAL JOURNAL OF CANCER

Phase I Clinical Trial of Autologous Ascites-derived Exosomes Combined With GM-CSF for Colorectal Cancer

(2008) Shengming Dai et al.   MOLECULAR THERAPY

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

(2008) Johan Skog et al.   NATURE CELL BIOLOGY

Dendritic Cells Release HLA-B-Associated Transcript-3 Positive Exosomes to Regulate Natural Killer Function

(2008) Venkateswara Rao Simhadri et al.   PLoS One

Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes

(2008) K. Trajkovic et al.   SCIENCE

Itinerant exosomes: emerging roles in cell and tissue polarity

(2008) Aparna Lakkaraju et al.   TRENDS IN CELL BIOLOGY