Exosome Release and Low pH Belong to a Framework of Resistance of Human Melanoma Cells to Cisplatin

A Rationale for the Use of Proton Pump Inhibitors as Antineoplastic Agents

(2012) Angelo De Milito et al.   CURRENT PHARMACEUTICAL DESIGN

LASS2 enhances chemosensitivity of breast cancer by counteracting acidic tumor microenvironment through inhibiting activity of V-ATPase proton pump

(2012) S Fan et al.   ONCOGENE

Lansoprazole as a rescue agent in chemoresistant tumors: a phase I/II study in companion animals with spontaneously occurring tumors

(2011) Enrico P Spugnini et al.   Journal of Translational Medicine

Cisplatin regulates the MAPK kinase pathway to induce increased expression of DNA repair gene ERCC1 and increase melanoma chemoresistance

(2011) W Li et al.   ONCOGENE

Proton pump inhibitor-induced tumour cell death by inhibition of a detoxification mechanism

(2010) S. Fais   JOURNAL OF INTERNAL MEDICINE

Novel strategies for reversing platinum resistance

(2009) Mian M.K. Shahzad et al.   DRUG RESISTANCE UPDATES

pH-dependent antitumor activity of proton pump inhibitors against human melanoma is mediated by inhibition of tumor acidity

(2009) Angelo De Milito et al.   INTERNATIONAL JOURNAL OF CANCER

Microenvironmental pH Is a Key Factor for Exosome Traffic in Tumor Cells

(2009) Isabella Parolini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Platinum neurotoxicity pharmacogenetics

(2009) S. R. McWhinney et al.   MOLECULAR CANCER THERAPEUTICS

High Levels of Exosomes Expressing CD63 and Caveolin-1 in Plasma of Melanoma Patients

(2009) Mariantonia Logozzi et al.   PLoS One