Pivotal role of paracrine effects in stem cell therapies in regenerative medicine: can we translate stem cell-secreted paracrine factors and microvesicles into better therapeutic strategies?

Exosomes From Human CD34 + Stem Cells Mediate Their Proangiogenic Paracrine Activity

(2011) Susmita Sahoo et al.   CIRCULATION RESEARCH

Stem cell self-renewal: lessons from bone marrow, gut and iPS toward clinical applications

(2011) F J T Staal et al.   LEUKEMIA

Bone marrow stem cell mobilization in stroke: a ‘bonehead’ may be good after all!

(2011) C V Borlongan   LEUKEMIA

Microvesicles derived from human adult mesenchymal stem cells protect against ischaemia-reperfusion-induced acute and chronic kidney injury

(2011) S. Gatti et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Adipose Stem Cell Treatment in Mice Attenuates Lung and Systemic Injury Induced by Cigarette Smoking

(2010) Kelly S. Schweitzer et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Stem cell plasticity revisited: The continuum marrow model and phenotypic changes mediated by microvesicles

(2010) Peter J. Quesenberry et al.   EXPERIMENTAL HEMATOLOGY

Mesenchymal stem cells at the intersection of cell and gene therapy

(2010) Timothy J Myers et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Novel insight into stem cell mobilization-Plasma sphingosine-1-phosphate is a major chemoattractant that directs the egress of hematopoietic stem progenitor cells from the bone marrow and its level in peripheral blood increases during mobilization due to activation of complement cascade/membrane attack complex

(2010) M Z Ratajczak et al.   LEUKEMIA

Molecular signature of adult bone marrow-purified very small embryonic-like stem cells supports their developmental epiblast/germ line origin

(2010) D-M Shin et al.   LEUKEMIA

Microvesicles Derived from Adult Human Bone Marrow and Tissue Specific Mesenchymal Stem Cells Shuttle Selected Pattern of miRNAs

(2010) Federica Collino et al.   PLoS One

Paracrine/endocrine mechanism of stem cells on kidney repair: role of microvesicle-mediated transfer of genetic information

(2009) Giovanni Camussi et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Intracoronary infusion of bone marrow-derived selected CD34+CXCR4+ cells and non-selected mononuclear cells in patients with acute STEMI and reduced left ventricular ejection fraction: results of randomized, multicentre Myocardial Regeneration by Intracoronary Infusion of Selected Population of Stem Cells in Acute Myocardial Infarction (REGENT) Trial

(2009) Michał Tendera et al.   EUROPEAN HEART JOURNAL

Human liver stem cell-derived microvesicles accelerate hepatic regeneration in hepatectomized rats

(2009) M. B. Herrera et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Novel epigenetic mechanisms that control pluripotency and quiescence of adult bone marrow-derived Oct4+ very small embryonic-like stem cells

(2009) D M Shin et al.   LEUKEMIA

Hunt for pluripotent stem cell – Regenerative medicine search for almighty cell

(2008) Mariusz Z. Ratajczak et al.   JOURNAL OF AUTOIMMUNITY