Exosome removal as a therapeutic adjuvant in cancer

Interaction and uptake of exosomes by ovarian cancer cells

(2011) Cristina Escrevente et al.   BMC CANCER

Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC

(2011) Christina Battke et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Microvesicles Released from Human Renal Cancer Stem Cells Stimulate Angiogenesis and Formation of Lung Premetastatic Niche

(2011) C. Grange et al.   CANCER RESEARCH

The EGFR Ligands Amphiregulin and Heparin-Binding EGF-like Growth Factor Promote Peritoneal Carcinomatosis in CXCR4-Expressing Gastric Cancer

(2011) K. Yasumoto et al.   CLINICAL CANCER RESEARCH

Amphiregulin Exosomes Increase Cancer Cell Invasion

(2011) James N. Higginbotham et al.   CURRENT BIOLOGY

Oral tolerance

(2011) Howard L. Weiner et al.   IMMUNOLOGICAL REVIEWS

Potential role of HER2-overexpressing exosomes in countering trastuzumab-based therapy

(2011) Valentina Ciravolo et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Cancer Exosomes Express CD39 and CD73, Which Suppress T Cells through Adenosine Production

(2011) A. Clayton et al.   JOURNAL OF IMMUNOLOGY

Insulinoma-Released Exosomes or Microparticles Are Immunostimulatory and Can Activate Autoreactive T Cells Spontaneously Developed in Nonobese Diabetic Mice

(2011) H. Sheng et al.   JOURNAL OF IMMUNOLOGY

Identification of a Conserved Glycan Signature for Microvesicles

(2011) Bianca S. Batista et al.   JOURNAL OF PROTEOME RESEARCH

Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells

(2011) Kamila A. Adamczyk et al.   LIFE SCIENCES

Thermal- and Oxidative Stress Causes Enhanced Release of NKG2D Ligand-Bearing Immunosuppressive Exosomes in Leukemia/Lymphoma T and B Cells

(2011) Malin Hedlund et al.   PLoS One

Detachment of Breast Tumor Cells Induces Rapid Secretion of Exosomes Which Subsequently Mediate Cellular Adhesion and Spreading

(2011) Rainelli B. Koumangoye et al.   PLoS One

Exosomal evasion of humoral immunotherapy in aggressive B-cell lymphoma modulated by ATP-binding cassette transporter A3

(2011) T. Aung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dendritic Cell-Derived Exosomes for Cancer Immunotherapy: What's Next?

(2010) S. Viaud et al.   CANCER RESEARCH

Natural Killer Cell Cytotoxicity Is Suppressed by Exposure to the Human NKG2D Ligand MICA*008 That Is Shed by Tumor Cells in Exosomes

(2010) O. Ashiru et al.   CANCER RESEARCH

HER2 as a target for breast cancer therapy

(2010) Elda Tagliabue et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Differential Mechanisms of Shedding of the Glycosylphosphatidylinositol (GPI)-anchored NKG2D Ligands

(2010) Lola Fernández-Messina et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proton pump inhibitors as anti vacuolar-ATPases drugs: a novel anticancer strategy

(2010) Enrico P Spugnini et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Induction of pregnancy during established EAE halts progression of CNS autoimmune injury via pregnancy-specific serum factors☆

(2010) NaTosha N. Gatson et al.   JOURNAL OF NEUROIMMUNOLOGY

Exosomes Derived from Immature Bone Marrow Dendritic Cells Induce Tolerogenicity of Intestinal Transplantation in Rats

(2010) Xiaojun Yang et al.   JOURNAL OF SURGICAL RESEARCH

Oncogenic mutations regulate tumor microenvironment through induction of growth factors and angiogenic mediators

(2010) S E Wang et al.   ONCOGENE

Tumor-Derived Microvesicles Induce, Expand and Up-Regulate Biological Activities of Human Regulatory T Cells (Treg)

(2010) Marta Szajnik et al.   PLoS One

Evaluation of tumor markers (HER-2/neu oncoprotein, CEA, and CA 15.3) in patients with locoregional breast cancer: prognostic value

(2010) Rafael Molina et al.   TUMOR BIOLOGY

Prostate cancer-derived urine exosomes: a novel approach to biomarkers for prostate cancer

(2009) J Nilsson et al.   BRITISH JOURNAL OF CANCER

Signaling Defects and Functional Impairment in T-Cells from Cervical Cancer Patients

(2009) Vino T. Cheriyan et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

Can the condition of the cell microenvironment of mediastinal lymph nodes help predict the risk of metastases in non-small cell lung cancer?

(2009) Paweł Zieliński et al.   Cancer Epidemiology

Circulating tumour-derived microvesicles in plasma of gastric cancer patients

(2009) Jaroslaw Baran et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Exosomal MicroRNA: A Diagnostic Marker for Lung Cancer

(2009) Guilherme Rabinowits et al.   Clinical Lung Cancer

B7-1/2, but not PD-L1/2 molecules, are required on IL-10-treated tolerogenic DC and DC-derived exosomes forin vivofunction

(2009) Melanie A. Ruffner et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Exosomes: proteomic insights and diagnostic potential

(2009) Richard J Simpson et al.   Expert Review of Proteomics

pH-dependent antitumor activity of proton pump inhibitors against human melanoma is mediated by inhibition of tumor acidity

(2009) Angelo De Milito et al.   INTERNATIONAL JOURNAL OF CANCER

Microenvironmental pH Is a Key Factor for Exosome Traffic in Tumor Cells

(2009) Isabella Parolini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human Placenta Expresses and Secretes NKG2D Ligands via Exosomes that Down-Modulate the Cognate Receptor Expression: Evidence for Immunosuppressive Function

(2009) M. Hedlund et al.   JOURNAL OF IMMUNOLOGY

Tumor-Derived Microvesicles Promote Regulatory T Cell Expansion and Induce Apoptosis in Tumor-Reactive Activated CD8+ T Lymphocytes

(2009) E. U. Wieckowski et al.   JOURNAL OF IMMUNOLOGY

Can urinary exosomes act as treatment response markers in prostate cancer?

(2009) Paul J Mitchell et al.   Journal of Translational Medicine

Dendritic Cell-Derived Exosomes Promote Natural Killer Cell Activation and Proliferation: A Role for NKG2D Ligands and IL-15Rα

(2009) Sophie Viaud et al.   PLoS One

High Levels of Exosomes Expressing CD63 and Caveolin-1 in Plasma of Melanoma Patients

(2009) Mariantonia Logozzi et al.   PLoS One

Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR

(2009) K. Al-Nedawi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exosomes are an effective vaccine against congenital toxoplasmosis in mice

(2009) Céline Beauvillain et al.   VACCINE

A multicenter, double-blind, randomized, controlled phase III clinical trial of chicken type II collagen in rheumatoid arthritis

(2009) Wei Wei et al.   ARTHRITIS RESEARCH & THERAPY

Evaluation of serum HER2 extracellular domain in early breast cancer patients: correlation with clinicopathological parameters and survival

(2008) V. Ludovini et al.   ANNALS OF ONCOLOGY

Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin–cyclophosphamide chemotherapy

(2008) C. Marcela Diaz-Montero et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Proteomic and immunologic analyses of brain tumor exosomes

(2008) Michael W. Graner et al.   FASEB JOURNAL

MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer

(2008) Douglas D. Taylor et al.   GYNECOLOGIC ONCOLOGY

Tumor-derived microvesicles in sera of patients with head and neck cancer and their role in tumor progression

(2008) Christoph Bergmann et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

NKG2D-Deficient Mice Are Defective in Tumor Surveillance in Models of Spontaneous Malignancy

(2008) Nadia Guerra et al.   IMMUNITY

Serum-derived exosomes from antigen-fed mice prevent allergic sensitization in a model of allergic asthma

(2008) Nina Almqvist et al.   IMMUNOLOGY

Induction of myeloid-derived suppressor cells by tumor exosomes

(2008) Xiaoyu Xiang et al.   INTERNATIONAL JOURNAL OF CANCER

Mechanisms involved in the down-regulation of TCR ζ chain in tumor versus peripheral blood of oral cancer patients

(2008) Dakshayini P. Kulkarni et al.   INTERNATIONAL JOURNAL OF CANCER

Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells

(2008) Khalid Al-Nedawi et al.   NATURE CELL BIOLOGY

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

(2008) Johan Skog et al.   NATURE CELL BIOLOGY

Exosomes Derived from M. Bovis BCG Infected Macrophages Activate Antigen-Specific CD4+ and CD8+ T Cells In Vitro and In Vivo

(2008) Pramod K. Giri et al.   PLoS One

Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes

(2008) K. Trajkovic et al.   SCIENCE