Exosomes Derived from Hypoxic Leukemia Cells Enhance Tube Formation in Endothelial Cells

EphA3 Maintains Tumorigenicity and Is a Therapeutic Target in Glioblastoma Multiforme

(2013) Bryan W. Day et al.   CANCER CELL

Neutral Sphingomyelinase 2 (nSMase2)-dependent Exosomal Transfer of Angiogenic MicroRNAs Regulate Cancer Cell Metastasis

(2013) Nobuyoshi Kosaka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exosomes: Current knowledge of their composition, biological functions, and diagnostic and therapeutic potentials

(2012) Alexander V. Vlassov et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Hypoxic enhancement of exosome release by breast cancer cells

(2012) Hamish W King et al.   BMC CANCER

Leukemia cell to endothelial cell communication via exosomal miRNAs

(2012) T Umezu et al.   ONCOGENE

Carboxyamidotriazole-Orotate Inhibits the Growth of Imatinib-Resistant Chronic Myeloid Leukaemia Cells and Modulates Exosomes-Stimulated Angiogenesis

(2012) Chiara Corrado et al.   PLoS One

Molecular mechanisms mediating metastasis of hypoxic breast cancer cells

(2012) Gregg L. Semenza   TRENDS IN MOLECULAR MEDICINE

Exosomes released by K562 chronic myeloid leukemia cells promote angiogenesis in a src-dependent fashion

(2011) Marco Mineo et al.   ANGIOGENESIS

Targeting hypoxic tumour cells to overcome metastasis

(2011) Kevin L Bennewith et al.   BMC CANCER

Exosomes Released by Melanoma Cells Prepare Sentinel Lymph Nodes for Tumor Metastasis

(2011) J. L. Hood et al.   CANCER RESEARCH

Role of exosomes released by chronic myelogenous leukemia cells in angiogenesis

(2011) Simona Taverna et al.   INTERNATIONAL JOURNAL OF CANCER

Competitive Interactions of Cancer Cells and Normal Cells via Secretory MicroRNAs

(2011) Nobuyoshi Kosaka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hypoxia triggers a proangiogenic pathway involving cancer cell microvesicles and PAR-2–mediated heparin-binding EGF signaling in endothelial cells

(2011) Katrin J. Svensson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypoxia inducible factors in cancer stem cells

(2010) J M Heddleston et al.   BRITISH JOURNAL OF CANCER

Cell Surface Tetraspanin Tspan8 Contributes to Molecular Pathways of Exosome-Induced Endothelial Cell Activation

(2010) I. Nazarenko et al.   CANCER RESEARCH

Cancer Exosomes Trigger Fibroblast to Myofibroblast Differentiation

(2010) J. Webber et al.   CANCER RESEARCH

Secretory Mechanisms and Intercellular Transfer of MicroRNAs in Living Cells

(2010) Nobuyoshi Kosaka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hypoxic Tumor Cell Modulates Its Microenvironment to Enhance Angiogenic and Metastatic Potential by Secretion of Proteins and Exosomes

(2010) Jung Eun Park et al.   MOLECULAR & CELLULAR PROTEOMICS

MiR-210 – micromanager of the hypoxia pathway

(2010) Xin Huang et al.   TRENDS IN MOLECULAR MEDICINE

Microenvironmental regulation of cancer development

(2008) Min Hu et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

MicroRNA-210 Modulates Endothelial Cell Response to Hypoxia and Inhibits the Receptor Tyrosine Kinase Ligand Ephrin-A3

(2008) Pasquale Fasanaro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hypoxia-induced resistance to anticancer drugs is associated with decreased senescence and requires hypoxia-inducible factor-1 activity

(2008) R. Sullivan et al.   MOLECULAR CANCER THERAPEUTICS

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

(2008) Johan Skog et al.   NATURE CELL BIOLOGY