- Home
- Publications
- Publication Search
- Publication Details
Title
Native-like Env trimers as a platform for HIV-1 vaccine design
Authors
Keywords
-
Journal
IMMUNOLOGICAL REVIEWS
Volume 275, Issue 1, Pages 161-182
Publisher
Wiley
Online
2017-01-30
DOI
10.1111/imr.12481
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Survivors Remorse: antibody-mediated protection against HIV-1
- (2017) George K. Lewis et al. IMMUNOLOGICAL REVIEWS
- The HIV-1 envelope glycoprotein structure: nailing down a moving target
- (2017) Andrew B Ward et al. IMMUNOLOGICAL REVIEWS
- Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody
- (2016) Mattia Bonsignori et al. CELL
- Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G
- (2016) Guillaume B.E. Stewart-Jones et al. CELL
- New concepts in HIV-1 vaccine development
- (2016) Kathryn E Stephenson et al. CURRENT OPINION IN IMMUNOLOGY
- Beyond antigens and adjuvants: formulating future vaccines
- (2016) Tyson J. Moyer et al. JOURNAL OF CLINICAL INVESTIGATION
- Achieving Potent Autologous Neutralizing Antibody Responses against Tier 2 HIV-1 Viruses by Strategic Selection of Envelope Immunogens
- (2016) Ann J. Hessell et al. JOURNAL OF IMMUNOLOGY
- Induction of Heterologous Tier 2 HIV-1-Neutralizing and Cross-Reactive V1/V2-Specific Antibodies in Rabbits by Prime-Boost Immunization
- (2016) Samantha Townsley et al. JOURNAL OF VIROLOGY
- Virus-Like Particles Displaying Trimeric Simian Immunodeficiency Virus (SIV) Envelope gp160 Enhance the Breadth of DNA/Modified Vaccinia Virus Ankara SIV Vaccine-Induced Antibody Responses in Rhesus Macaques
- (2016) Smita S. Iyer et al. JOURNAL OF VIROLOGY
- Design of a hyperstable 60-subunit protein icosahedron
- (2016) Yang Hsia et al. NATURE
- Is There an Optimal Formulation and Delivery Strategy for Subunit Vaccines?
- (2016) Sharan Bobbala et al. PHARMACEUTICAL RESEARCH
- Comparative Immunogenicity of HIV-1 gp140 Vaccine Delivered by Parenteral, and Mucosal Routes in Female Volunteers; MUCOVAC2, A Randomized Two Centre Study
- (2016) Catherine A. Cosgrove et al. PLoS One
- Cryo-EM structure of a native, fully glycosylated, cleaved HIV-1 envelope trimer
- (2016) J. H. Lee et al. SCIENCE
- HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen
- (2016) J. G. Jardine et al. SCIENCE
- Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody
- (2016) R. Kong et al. SCIENCE
- Accurate design of megadalton-scale two-component icosahedral protein complexes
- (2016) J. B. Bale et al. SCIENCE
- Presenting native-like trimeric HIV-1 antigens with self-assembling nanoparticles
- (2016) Linling He et al. Nature Communications
- Specifically modified Env immunogens activate B-cell precursors of broadly neutralizing HIV-1 antibodies in transgenic mice
- (2016) Andrew T. McGuire et al. Nature Communications
- Uncleaved prefusion-optimized gp140 trimers derived from analysis of HIV-1 envelope metastability
- (2016) Leopold Kong et al. Nature Communications
- High-Density Array of Well-Ordered HIV-1 Spikes on Synthetic Liposomal Nanoparticles Efficiently Activate B Cells
- (2016) Jidnyasa Ingale et al. Cell Reports
- Composition and Antigenic Effects of Individual Glycan Sites of a Trimeric HIV-1 Envelope Glycoprotein
- (2016) Anna-Janina Behrens et al. Cell Reports
- Holes in the Glycan Shield of the Native HIV Envelope Are a Target of Trimer-Elicited Neutralizing Antibodies
- (2016) Laura E. McCoy et al. Cell Reports
- Structural Constraints of Vaccine-Induced Tier-2 Autologous HIV Neutralizing Antibodies Targeting the Receptor-Binding Site
- (2016) Todd Bradley et al. Cell Reports
- Thermostability of Well-Ordered HIV Spikes Correlates with the Elicitation of Autologous Tier 2 Neutralizing Antibodies
- (2016) Yu Feng et al. PLoS Pathogens
- Sequential and Simultaneous Immunization of Rabbits with HIV-1 Envelope Glycoprotein SOSIP.664 Trimers from Clades A, B and C
- (2016) P. J. Klasse et al. PLoS Pathogens
- Structural basis for germline antibody recognition of HIV-1 immunogens
- (2016) Louise Scharf et al. eLife
- An HIV-1 antibody from an elite neutralizer implicates the fusion peptide as a site of vulnerability
- (2016) Marit J. van Gils et al. Nature Microbiology
- Generation and Characterization of a Bivalent HIV-1 Subtype C gp120 Protein Boost for Proof-of-Concept HIV Vaccine Efficacy Trials in Southern Africa
- (2016) Carlo Zambonelli et al. PLoS One
- Broadly Neutralizing Antibody 8ANC195 Recognizes Closed and Open States of HIV-1 Env
- (2015) Louise Scharf et al. CELL
- Immunogenicity of Stabilized HIV-1 Envelope Trimers with Reduced Exposure of Non-neutralizing Epitopes
- (2015) Steven W. de Taeye et al. CELL
- Rational Design of an Epstein-Barr Virus Vaccine Targeting the Receptor-Binding Site
- (2015) Masaru Kanekiyo et al. CELL
- Immunization for HIV-1 Broadly Neutralizing Antibodies in Human Ig Knockin Mice
- (2015) Pia Dosenovic et al. CELL
- Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans
- (2015) Fernando Garces et al. IMMUNITY
- Identification of Common Features in Prototype Broadly Neutralizing Antibodies to HIV Envelope V2 Apex to Facilitate Vaccine Design
- (2015) Raiees Andrabi et al. IMMUNITY
- A New Approach to Produce HIV-1 Envelope Trimers
- (2015) Wadad AlSalmi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Immunosilencing a Highly Immunogenic Protein Trimerization Domain
- (2015) Kwinten Sliepen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Comparable Antigenicity and Immunogenicity of Oligomeric Forms of a Novel, Acute HIV-1 Subtype C gp145 Envelope for Use in Preclinical and Clinical Vaccine Research
- (2015) Lindsay Wieczorek et al. JOURNAL OF VIROLOGY
- HIV-1 Fitness Cost Associated with Escape from the VRC01 Class of CD4 Binding Site Neutralizing Antibodies
- (2015) Rebecca M. Lynch et al. JOURNAL OF VIROLOGY
- Immunogenicity of a Prefusion HIV-1 Envelope Trimer in Complex with a Quaternary-Structure-Specific Antibody
- (2015) Cheng Cheng et al. JOURNAL OF VIROLOGY
- Influences on the Design and Purification of Soluble, Recombinant Native-Like HIV-1 Envelope Glycoprotein Trimers
- (2015) Rajesh P. Ringe et al. JOURNAL OF VIROLOGY
- A Native-Like SOSIP.664 Trimer Based on an HIV-1 Subtype BenvGene
- (2015) Pavel Pugach et al. JOURNAL OF VIROLOGY
- Structure-Guided Redesign Increases the Propensity of HIV Env To Generate Highly Stable Soluble Trimers
- (2015) Javier Guenaga et al. JOURNAL OF VIROLOGY
- Chemical Cross-Linking Stabilizes Native-Like HIV-1 Envelope Glycoprotein Trimer Antigens
- (2015) Torben Schiffner et al. JOURNAL OF VIROLOGY
- Comparative Analysis of the Glycosylation Profiles of Membrane-Anchored HIV-1 Envelope Glycoprotein Trimers and Soluble gp140
- (2015) Eden P. Go et al. JOURNAL OF VIROLOGY
- New Member of the V1V2-Directed CAP256-VRC26 Lineage That Shows Increased Breadth and Exceptional Potency
- (2015) Nicole A. Doria-Rose et al. JOURNAL OF VIROLOGY
- Native Conformation and Canonical Disulfide Bond Formation Are Interlinked Properties of HIV-1 Env Glycoproteins
- (2015) Eden P. Go et al. JOURNAL OF VIROLOGY
- Murine Antibody Responses to Cleaved Soluble HIV-1 Envelope Trimers Are Highly Restricted in Specificity
- (2015) Joyce K. Hu et al. JOURNAL OF VIROLOGY
- Single-Chain Soluble BG505.SOSIP gp140 Trimers as Structural and Antigenic Mimics of Mature Closed HIV-1 Env
- (2015) Ivelin S. Georgiev et al. JOURNAL OF VIROLOGY
- Antibody responses to envelope glycoproteins in HIV-1 infection
- (2015) Dennis R Burton et al. NATURE IMMUNOLOGY
- Hemagglutinin-stem nanoparticles generate heterosubtypic influenza protection
- (2015) Hadi M Yassine et al. NATURE MEDICINE
- Viral variants that initiate and drive maturation of V1V2-directed HIV-1 broadly neutralizing antibodies
- (2015) Jinal N Bhiman et al. NATURE MEDICINE
- Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design
- (2015) Jason Gorman et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env
- (2015) Young Do Kwon et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Design and structure of two HIV-1 clade C SOSIP.664 trimers that increase the arsenal of native-like Env immunogens
- (2015) Jean-Philippe Julien et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Presenting native-like HIV-1 envelope trimers on ferritin nanoparticles improves their immunogenicity
- (2015) Kwinten Sliepen et al. Retrovirology
- Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen
- (2015) J. G. Jardine et al. SCIENCE
- HIV-1 neutralizing antibodies induced by native-like envelope trimers
- (2015) R. W. Sanders et al. SCIENCE
- Binding of inferred germline precursors of broadly neutralizing HIV-1 antibodies to native-like envelope trimers
- (2015) Kwinten Sliepen et al. VIROLOGY
- Viral membrane fusion
- (2015) Stephen C. Harrison VIROLOGY
- Antibody potency relates to the ability to recognize the closed, pre-fusion form of HIV Env
- (2015) Miklos Guttman et al. Nature Communications
- Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design
- (2015) Jason Gorman et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env
- (2015) Young Do Kwon et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Structural Constraints Determine the Glycosylation of HIV-1 Envelope Trimers
- (2015) Laura K. Pritchard et al. Cell Reports
- Cleavage-Independent HIV-1 Env Trimers Engineered as Soluble Native Spike Mimetics for Vaccine Design
- (2015) Shailendra Kumar Sharma et al. Cell Reports
- Comprehensive Antigenic Map of a Cleaved Soluble HIV-1 Envelope Trimer
- (2015) Ronald Derking et al. PLoS Pathogens
- Vaccine-Elicited Tier 2 HIV-1 Neutralizing Antibodies Bind to Quaternary Epitopes Involving Glycan-Deficient Patches Proximal to the CD4 Binding Site
- (2015) Ema T. Crooks et al. PLoS Pathogens
- Well-Ordered Trimeric HIV-1 Subtype B and C Soluble Spike Mimetics Generated by Negative Selection Display Native-like Properties
- (2015) Javier Guenaga et al. PLoS Pathogens
- Complete epitopes for vaccine design derived from a crystal structure of the broadly neutralizing antibodies PGT128 and 8ANC195 in complex with an HIV-1 Env trimer
- (2015) Leopold Kong et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Early development of broadly reactive HIV-1 neutralizing activity in elite neutralizers
- (2014) Tom L.G.M. van den Kerkhof et al. AIDS
- Design of Lipid Nanocapsule Delivery Vehicles for Multivalent Display of Recombinant Env Trimers in HIV Vaccination
- (2014) Sharmila Pejawar-Gaddy et al. BIOCONJUGATE CHEMISTRY
- Targeting B-cell germlines and focusing affinity maturation: the next hurdles in HIV-1-vaccine development?
- (2014) Max Medina-Ramírez et al. Expert Review of Vaccines
- Broadly Neutralizing HIV Antibodies Define a Glycan-Dependent Epitope on the Prefusion Conformation of gp41 on Cleaved Envelope Trimers
- (2014) Emilia Falkowska et al. IMMUNITY
- Structural Delineation of a Quaternary, Cleavage-Dependent Epitope at the gp41-gp120 Interface on Intact HIV-1 Env Trimers
- (2014) Claudia Blattner et al. IMMUNITY
- Glycosylation and Disulfide Bond Analysis of Transiently and Stably Expressed Clade C HIV-1 gp140 Trimers in 293T Cells Identifies Disulfide Heterogeneity Present in Both Proteins and Differences in O-Linked Glycosylation
- (2014) Eden P. Go et al. JOURNAL OF PROTEOME RESEARCH
- Envelope Variants Circulating as Initial Neutralization Breadth Developed in Two HIV-Infected Subjects Stimulate Multiclade Neutralizing Antibodies in Rabbits
- (2014) D. C. Malherbe et al. JOURNAL OF VIROLOGY
- Broad and potent HIV-1 neutralization by a human antibody that binds the gp41–gp120 interface
- (2014) Jinghe Huang et al. NATURE
- A stamp on the envelope
- (2014) Rogier W. Sanders et al. NATURE
- Structure and immune recognition of trimeric pre-fusion HIV-1 Env
- (2014) Marie Pancera et al. NATURE
- Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies
- (2014) Nicole A. Doria-Rose et al. NATURE
- Early development of broadly neutralizing antibodies in HIV-1–infected infants
- (2014) Leslie Goo et al. NATURE MEDICINE
- Affinity maturation in an HIV broadly neutralizing B-cell lineage through reorientation of variable domains
- (2014) D. Fera et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Stable, uncleaved HIV-1 envelope glycoprotein gp140 forms a tightly folded trimer with a native-like structure
- (2014) James M. Kovacs et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Vaccine-elicited primate antibodies use a distinct approach to the HIV-1 primary receptor binding site informing vaccine redesign
- (2014) K. Tran et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex
- (2014) Devin Sok et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Differential binding of neutralizing and non-neutralizing antibodies to native-like soluble HIV-1 Env trimers, uncleaved Env proteins, and monomeric subunits
- (2014) Anila Yasmeen et al. Retrovirology
- Stable 293 T and CHO cell lines expressing cleaved, stable HIV-1 envelope glycoprotein trimers for structural and vaccine studies
- (2014) Nancy PY Chung et al. Retrovirology
- Antigen modification regulates competition of broad and narrow neutralizing HIV antibodies
- (2014) A. T. McGuire et al. SCIENCE
- Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions
- (2014) J. B. Munro et al. SCIENCE
- CD4-Induced Activation in a Soluble HIV-1 Env Trimer
- (2014) Miklos Guttman et al. STRUCTURE
- In vivo protection by broadly neutralizing HIV antibodies
- (2014) Marit J. van Gils et al. TRENDS IN MICROBIOLOGY
- Eliciting neutralizing antibodies with gp120 outer domain constructs based on M-group consensus sequence
- (2014) Yali Qin et al. VIROLOGY
- Multi-parameter exploration of HIV-1 virus-like particles as neutralizing antibody immunogens in guinea pigs, rabbits and macaques
- (2014) Tommy Tong et al. VIROLOGY
- Antibody 8ANC195 Reveals a Site of Broad Vulnerability on the HIV-1 Envelope Spike
- (2014) Louise Scharf et al. Cell Reports
- Why HIV Virions Have Low Numbers of Envelope Spikes: Implications for Vaccine Development
- (2014) John Schiller et al. PLoS Pathogens
- Prevalence of broadly neutralizing antibody responses during chronic HIV-1 infection
- (2013) Peter Hraber et al. AIDS
- Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization
- (2013) Florian Klein et al. CELL
- HIV-1 neutralizing antibodies: understanding nature's pathways
- (2013) John R. Mascola et al. IMMUNOLOGICAL REVIEWS
- Engineering HIV envelope protein to activate germline B cell receptors of broadly neutralizing anti-CD4 binding site antibodies
- (2013) Andrew T. McGuire et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Germinal center B cells govern their own fate via antibody feedback
- (2013) Yang Zhang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- B Cell Activation Is Regulated by the Stiffness Properties of the Substrate Presenting the Antigens
- (2013) Z. Wan et al. JOURNAL OF IMMUNOLOGY
- HIV-1 Envelope Glycoprotein Trimers Display Open Quaternary Conformation When Bound to the gp41 Membrane-Proximal External-Region-Directed Broadly Neutralizing Antibody Z13e1
- (2013) A. K. Harris et al. JOURNAL OF VIROLOGY
- Immune Focusing and Enhanced Neutralization Induced by HIV-1 gp140 Chemical Cross-Linking
- (2013) T. Schiffner et al. JOURNAL OF VIROLOGY
- Structural Characterization of Cleaved, Soluble HIV-1 Envelope Glycoprotein Trimers
- (2013) R. Khayat et al. JOURNAL OF VIROLOGY
- Influences on Trimerization and Aggregation of Soluble, Cleaved HIV-1 SOSIP Envelope Glycoprotein
- (2013) P. J. Klasse et al. JOURNAL OF VIROLOGY
- Diverse Recombinant HIV-1 Envs Fail To Activate B Cells Expressing the Germline B Cell Receptors of the Broadly Neutralizing Anti-HIV-1 Antibodies PG9 and 447-52D
- (2013) A. T. McGuire et al. JOURNAL OF VIROLOGY
- A Functional Interaction between gp41 and gp120 Is Observed for Monomeric but Not Oligomeric, Uncleaved HIV-1 Env gp140
- (2013) M. Guttman et al. JOURNAL OF VIROLOGY
- Robust Neutralizing Antibodies Elicited by HIV-1 JRFL Envelope Glycoprotein Trimers in Nonhuman Primates
- (2013) B. K. Chakrabarti et al. JOURNAL OF VIROLOGY
- Self-assembling influenza nanoparticle vaccines elicit broadly neutralizing H1N1 antibodies
- (2013) Masaru Kanekiyo et al. NATURE
- Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus
- (2013) Hua-Xin Liao et al. NATURE
- Prefusion structure of trimeric HIV-1 envelope glycoprotein determined by cryo-electron microscopy
- (2013) Alberto Bartesaghi et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Cleavage strongly influences whether soluble HIV-1 envelope glycoprotein trimers adopt a native-like conformation
- (2013) R. P. Ringe et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Asymmetric recognition of the HIV-1 trimer by broadly neutralizing antibody PG9
- (2013) Jean-Philippe Julien et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Crystal Structure of a Soluble Cleaved HIV-1 Envelope Trimer
- (2013) J.-P. Julien et al. SCIENCE
- Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer
- (2013) D. Lyumkis et al. SCIENCE
- Antibodies in HIV-1 Vaccine Development and Therapy
- (2013) F. Klein et al. SCIENCE
- Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors
- (2013) J. Jardine et al. SCIENCE
- Virus-like particle-based human vaccines: quality assessment based on structural and functional properties
- (2013) Qinjian Zhao et al. TRENDS IN BIOTECHNOLOGY
- Chemical cross-linking of HIV-1 Env for direct TLR7/8 ligand conjugation compromises recognition of conserved antigenic determinants
- (2013) Yu Feng et al. VIROLOGY
- Characterization of virus-like particles in GARDASIL® by cryo transmission electron microscopy
- (2013) Qinjian Zhao et al. Human Vaccines & Immunotherapeutics
- Recombinant HIV Envelope Proteins Fail to Engage Germline Versions of Anti-CD4bs bNAbs
- (2013) Sam Hoot et al. PLoS Pathogens
- A Next-Generation Cleaved, Soluble HIV-1 Env Trimer, BG505 SOSIP.664 gp140, Expresses Multiple Epitopes for Broadly Neutralizing but Not Non-Neutralizing Antibodies
- (2013) Rogier W. Sanders et al. PLoS Pathogens
- Simple Approach to Assign Disulfide Connectivity Using Extracted Ion Chromatograms of Electron Transfer Dissociation Spectra
- (2012) Daniel F. Clark et al. ANALYTICAL CHEMISTRY
- Glycan profiles of the 27 N-glycosylation sites of the HIV envelope protein CN54gp140
- (2012) Martin Pabst et al. BIOLOGICAL CHEMISTRY
- Anti-HIV B Cell Lines as Candidate Vaccine Biosensors
- (2012) T. Ota et al. JOURNAL OF IMMUNOLOGY
- HIV-1 Virus-Like Particles Bearing Pure Env Trimers Expose Neutralizing Epitopes but Occlude Nonneutralizing Epitopes
- (2012) T. Tong et al. JOURNAL OF VIROLOGY
- Proteolytic Processing of the Human Immunodeficiency Virus Envelope Glycoprotein Precursor Decreases Conformational Flexibility
- (2012) Hillel Haim et al. JOURNAL OF VIROLOGY
- B-cell–lineage immunogen design in vaccine development with HIV-1 as a case study
- (2012) Barton F Haynes et al. NATURE BIOTECHNOLOGY
- Toolbox for Non-Intrusive Structural and Functional Analysis of Recombinant VLP Based Vaccines: A Case Study with Hepatitis B Vaccine
- (2012) Anke M. Mulder et al. PLoS One
- HIV-1 envelope trimer elicits more potent neutralizing antibody responses than monomeric gp120
- (2012) James M. Kovacs et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Enhancing humoral responses to a malaria antigen with nanoparticle vaccines that expand Tfh cells and promote germinal center induction
- (2012) J. J. Moon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Broadly neutralizing antibodies against HIV-1: Templates for a vaccine
- (2012) Marit J. van Gils et al. VIROLOGY
- How Can HIV-Type-1-Env Immunogenicity Be Improved to Facilitate Antibody-Based Vaccine Development?
- (2011) Per Johan Klasse et al. AIDS RESEARCH AND HUMAN RETROVIRUSES
- Clinical evaluation of a soluble trimeric HIV-1 envelope glycoprotein vaccine
- (2011) Rogier W Sanders Expert Review of Vaccines
- A Trimeric, V2-Deleted HIV-1 Envelope Glycoprotein Vaccine Elicits Potent Neutralizing Antibodies but Limited Breadth of Neutralization in Human Volunteers
- (2011) Paul Spearman et al. JOURNAL OF INFECTIOUS DISEASES
- Targeting HIV-1 Envelope Glycoprotein Trimers to B Cells by Using APRIL Improves Antibody Responses
- (2011) M. Melchers et al. JOURNAL OF VIROLOGY
- Enzyme Digests Eliminate Nonfunctional Env from HIV-1 Particle Surfaces, Leaving Native Env Trimers Intact and Viral Infectivity Unaffected
- (2011) E. T. Crooks et al. JOURNAL OF VIROLOGY
- Programming the magnitude and persistence of antibody responses with innate immunity
- (2011) Sudhir Pai Kasturi et al. NATURE
- Broad neutralization coverage of HIV by multiple highly potent antibodies
- (2011) Laura M. Walker et al. NATURE
- Interbilayer-crosslinked multilamellar vesicles as synthetic vaccines for potent humoral and cellular immune responses
- (2011) James J. Moon et al. NATURE MATERIALS
- The Glycan Shield of HIV Is Predominantly Oligomannose Independently of Production System or Viral Clade
- (2011) Camille Bonomelli et al. PLoS One
- Phase I Randomised Clinical Trial of an HIV-1CN54, Clade C, Trimeric Envelope Vaccine Candidate Delivered Vaginally
- (2011) David J. Lewis et al. PLoS One
- Trimeric HIV-1 glycoprotein gp140 immunogens and native HIV-1 envelope glycoproteins display the same closed and open quaternary molecular architectures
- (2011) A. Harris et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Correlates of Protection Induced by Vaccination
- (2010) S. A. Plotkin Clinical and Vaccine Immunology
- Soluble HIV-1 Env trimers in adjuvant elicit potent and diverse functional B cell responses in primates
- (2010) Christopher Sundling et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Magnitude and Breadth of a Nonprotective Neutralizing Antibody Response in an Efficacy Trial of a Candidate HIV‐1 gp120 Vaccine
- (2010) Peter Gilbert et al. JOURNAL OF INFECTIOUS DISEASES
- Cross‐Reactive Neutralizing Humoral Immunity Does Not Protect from HIV Type 1 Disease Progression
- (2010) Zelda Euler et al. JOURNAL OF INFECTIOUS DISEASES
- Analysis of the Disulfide Bond Arrangement of the HIV-1 Envelope Protein CON-S gp140 ΔCFI Shows Variability in the V1 and V2 Regions
- (2010) Eden P. Go et al. JOURNAL OF PROTEOME RESEARCH
- Conformational characterization of aberrant disulfide-linked HIV-1 gp120 dimers secreted from overexpressing cells
- (2010) Andrés Finzi et al. JOURNAL OF VIROLOGICAL METHODS
- Breadth of Neutralizing Antibodies Elicited by Stable, Homogeneous Clade A and Clade C HIV-1 gp140 Envelope Trimers in Guinea Pigs
- (2010) J. P. Nkolola et al. JOURNAL OF VIROLOGY
- Crystal Structure of PG16 and Chimeric Dissection with Somatically Related PG9: Structure-Function Analysis of Two Quaternary-Specific Antibodies That Effectively Neutralize HIV-1
- (2010) M. Pancera et al. JOURNAL OF VIROLOGY
- Envelope glycans of immunodeficiency virions are almost entirely oligomannose antigens
- (2010) K. J. Doores et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- First phase I clinical trial of an HIV-1 subtype D gp140 envelope protein vaccine: immune activity induced in all study participants
- (2009) Julia L Hurwitz et al. AIDS
- Prevalence of cross-reactive HIV-1-neutralizing activity in HIV-1-infected patients with rapid or slow disease progression
- (2009) Marit J van Gils et al. AIDS
- Germline-like predecessors of broadly neutralizing antibodies lack measurable binding to HIV-1 envelope glycoproteins: Implications for evasion of immune responses and design of vaccine immunogens
- (2009) Xiaodong Xiao et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Comparative Immunogenicity of Subtype A Human Immunodeficiency Virus Type 1 Envelope Exhibiting Differential Exposure of Conserved Neutralization Epitopes
- (2009) C. A. Blish et al. JOURNAL OF VIROLOGY
- Human Immunodeficiency Virus Type 1 Elite Neutralizers: Individuals with Broad and Potent Neutralizing Activity Identified by Using a High-Throughput Neutralization Assay together with an Analytical Selection Algorithm
- (2009) M. D. Simek et al. JOURNAL OF VIROLOGY
- Structural and immunogenicity studies of a cleaved, stabilized envelope trimer derived from subtype A HIV-1
- (2009) Yun (Kenneth) Kang et al. VACCINE
- Effect of trimerization motifs on quaternary structure, antigenicity, and immunogenicity of a noncleavable HIV-1 gp140 envelope glycoprotein
- (2009) Sean X. Du et al. VIROLOGY
- Maturation Pathways of Cross-Reactive HIV-1 Neutralizing Antibodies
- (2009) Xiaodong Xiao et al. Viruses-Basel
- Profiling the Specificity of Neutralizing Antibodies in a Large Panel of Plasmas from Patients Chronically Infected with Human Immunodeficiency Virus Type 1 Subtypes B and C
- (2008) J. M. Binley et al. JOURNAL OF VIROLOGY
- Inhibition of V3-specific cleavage of recombinant HIV-1 gp120 produced in Chinese hamster ovary cells
- (2008) Sean X. Du et al. PROTEIN EXPRESSION AND PURIFICATION
- N-terminal substitutions in HIV-1 gp41 reduce the expression of non-trimeric envelope glycoproteins on the virus
- (2007) Antu K. Dey et al. VIROLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started