- Home
- Publications
- Publication Search
- Publication Details
Title
Structure and immune recognition of trimeric pre-fusion HIV-1 Env
Authors
Keywords
-
Journal
NATURE
Volume 514, Issue 7523, Pages 455-461
Publisher
Springer Nature
Online
2014-10-07
DOI
10.1038/nature13808
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Broadly Neutralizing HIV Antibodies Define a Glycan-Dependent Epitope on the Prefusion Conformation of gp41 on Cleaved Envelope Trimers
- (2014) Emilia Falkowska et al. IMMUNITY
- Structural Delineation of a Quaternary, Cleavage-Dependent Epitope at the gp41-gp120 Interface on Intact HIV-1 Env Trimers
- (2014) Claudia Blattner et al. IMMUNITY
- Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies
- (2014) Nicole A. Doria-Rose et al. NATURE
- Tyrosine sulfation in the second variable loop (V2) of HIV-1 gp120 stabilizes V2-V3 interaction and modulates neutralization sensitivity
- (2014) R. Cimbro et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Differential binding of neutralizing and non-neutralizing antibodies to native-like soluble HIV-1 Env trimers, uncleaved Env proteins, and monomeric subunits
- (2014) Anila Yasmeen et al. Retrovirology
- CD4-Induced Activation in a Soluble HIV-1 Env Trimer
- (2014) Miklos Guttman et al. STRUCTURE
- Antibody 8ANC195 Reveals a Site of Broad Vulnerability on the HIV-1 Envelope Spike
- (2014) Louise Scharf et al. Cell Reports
- Prevalence of broadly neutralizing antibody responses during chronic HIV-1 infection
- (2013) Peter Hraber et al. AIDS
- Mechanism of HIV-1 Neutralization by Antibodies Targeting a Membrane-Proximal Region of gp41
- (2013) J. Chen et al. JOURNAL OF VIROLOGY
- Self-assembling influenza nanoparticle vaccines elicit broadly neutralizing H1N1 antibodies
- (2013) Masaru Kanekiyo et al. NATURE
- Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus
- (2013) Hua-Xin Liao et al. NATURE
- Prefusion structure of trimeric HIV-1 envelope glycoprotein determined by cryo-electron microscopy
- (2013) Alberto Bartesaghi et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Cleavage strongly influences whether soluble HIV-1 envelope glycoprotein trimers adopt a native-like conformation
- (2013) R. P. Ringe et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Asymmetric recognition of the HIV-1 trimer by broadly neutralizing antibody PG9
- (2013) Jean-Philippe Julien et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A common solution to group 2 influenza virus neutralization
- (2013) R. H. E. Friesen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structure of RSV Fusion Glycoprotein Trimer Bound to a Prefusion-Specific Neutralizing Antibody
- (2013) J. S. McLellan et al. SCIENCE
- Delineating Antibody Recognition in Polyclonal Sera from Patterns of HIV-1 Isolate Neutralization
- (2013) I. S. Georgiev et al. SCIENCE
- Structure-Based Design of a Fusion Glycoprotein Vaccine for Respiratory Syncytial Virus
- (2013) J. S. McLellan et al. SCIENCE
- Crystal Structure of a Soluble Cleaved HIV-1 Envelope Trimer
- (2013) J.-P. Julien et al. SCIENCE
- Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer
- (2013) D. Lyumkis et al. SCIENCE
- Broadly Neutralizing Antibody PGT121 Allosterically Modulates CD4 Binding via Recognition of the HIV-1 gp120 V3 Base and Multiple Surrounding Glycans
- (2013) Jean-Philippe Julien et al. PLoS Pathogens
- A Next-Generation Cleaved, Soluble HIV-1 Env Trimer, BG505 SOSIP.664 gp140, Expresses Multiple Epitopes for Broadly Neutralizing but Not Non-Neutralizing Antibodies
- (2013) Rogier W. Sanders et al. PLoS Pathogens
- Cross-neutralization of influenza A viruses mediated by a single antibody loop
- (2012) Damian C. Ekiert et al. NATURE
- Broad and potent neutralization of HIV-1 by a gp41-specific human antibody
- (2012) Jinghe Huang et al. NATURE
- Subunit organization of the membrane-bound HIV-1 envelope glycoprotein trimer
- (2012) Youdong Mao et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Evolution of the receptor binding properties of the influenza A(H3N2) hemagglutinin
- (2012) Y. P. Lin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Diverse specificity and effector function among human antibodies to HIV-1 envelope glycoprotein epitopes exposed by CD4 binding
- (2012) Y. Guan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MPER-specific antibodies induce gp120 shedding and irreversibly neutralize HIV-1
- (2011) Claudia R. Ruprecht et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Structure of Respiratory Syncytial Virus Fusion Glycoprotein in the Postfusion Conformation Reveals Preservation of Neutralizing Epitopes
- (2011) J. S. McLellan et al. JOURNAL OF VIROLOGY
- Polyclonal B Cell Responses to Conserved Neutralization Epitopes in a Subset of HIV-1-Infected Individuals
- (2011) G. D. Tomaras et al. JOURNAL OF VIROLOGY
- Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9
- (2011) Jason S. McLellan et al. NATURE
- Broad neutralization coverage of HIV by multiple highly potent antibodies
- (2011) Laura M. Walker et al. NATURE
- Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding
- (2011) J. F. Scheid et al. SCIENCE
- HIV Type 1 Env Precursor Cleavage State Affects Recognition by Both Neutralizing and Nonneutralizing gp41 Antibodies
- (2010) Bimal K. Chakrabarti et al. AIDS RESEARCH AND HUMAN RETROVIRUSES
- Structure of a Major Antigenic Site on the Respiratory Syncytial Virus Fusion Glycoprotein in Complex with Neutralizing Antibody 101F
- (2010) J. S. McLellan et al. JOURNAL OF VIROLOGY
- Topological Layers in the HIV-1 gp120 Inner Domain Regulate gp41 Interaction and CD4-Triggered Conformational Transitions
- (2010) Andrés Finzi et al. MOLECULAR CELL
- Structural basis of respiratory syncytial virus neutralization by motavizumab
- (2010) Jason S McLellan et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Distinct conformational states of HIV-1 gp41 are recognized by neutralizing and non-neutralizing antibodies
- (2010) Gary Frey et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Crystal structure of a non-neutralizing antibody to the HIV-1 gp41 membrane-proximal external region
- (2010) Nathan I Nicely et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01
- (2010) T. Zhou et al. SCIENCE
- Structural Basis of Preexisting Immunity to the 2009 H1N1 Pandemic Influenza Virus
- (2010) R. Xu et al. SCIENCE
- Crystal Structure of HIV-1 gp41 Including Both Fusion Peptide and Membrane Proximal External Regions
- (2010) Victor Buzon et al. PLoS Pathogens
- Structural Basis of HIV-1 Neutralization by Affinity Matured Fabs Directed against the Internal Trimeric Coiled-Coil of gp41
- (2010) Elena Gustchina et al. PLoS Pathogens
- Crystal Structure and Size-Dependent Neutralization Properties of HK20, a Human Monoclonal Antibody Binding to the Highly Conserved Heptad Repeat 1 of gp41
- (2010) Charles Sabin et al. PLoS Pathogens
- Few and Far Between: How HIV May Be Evading Antibody Avidity
- (2010) Joshua S. Klein et al. PLoS Pathogens
- Molecular Architectures of Trimeric SIV and HIV-1 Envelope Glycoproteins on Intact Viruses: Strain-Dependent Variation in Quaternary Structure
- (2010) Tommi A. White et al. PLoS Pathogens
- Oligomer-Specific Conformations of the Human Immunodeficiency Virus (HIV-1) gp41 Envelope Glycoprotein Ectodomain Recognized by Human Monoclonal Antibodies
- (2009) Wen Yuan et al. AIDS RESEARCH AND HUMAN RETROVIRUSES
- Mitigating Unwanted Photophysical Processes for Improved Single-Molecule Fluorescence Imaging
- (2009) Richa Dave et al. BIOPHYSICAL JOURNAL
- Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses
- (2009) Jianhua Sui et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility
- (2009) M. Pancera et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural Basis of Immune Evasion at the Site of CD4 Attachment on HIV-1 gp120
- (2009) L. Chen et al. SCIENCE
- Broad and Potent Neutralizing Antibodies from an African Donor Reveal a New HIV-1 Vaccine Target
- (2009) L. M. Walker et al. SCIENCE
- Role of the HIV gp120 Conserved Domain 5 in Processing and Viral Entry†
- (2008) Jayita Sen et al. BIOCHEMISTRY
- Structural specificity in coiled-coil interactions
- (2008) G GRIGORYAN et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Role of the HIV gp120 Conserved Domain 1 in Processing and Viral Entry
- (2008) Jizhen Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Initial B-Cell Responses to Transmitted Human Immunodeficiency Virus Type 1: Virion-Binding Immunoglobulin M (IgM) and IgG Antibodies Followed by Plasma Anti-gp41 Antibodies with Ineffective Control of Initial Viremia
- (2008) G. D. Tomaras et al. JOURNAL OF VIROLOGY
- Molecular architecture of native HIV-1 gp120 trimers
- (2008) Jun Liu et al. NATURE
- Structure of the Ebola virus glycoprotein bound to an antibody from a human survivor
- (2008) Jeffrey E. Lee et al. NATURE
- A fusion-intermediate state of HIV-1 gp41 targeted by broadly neutralizing antibodies
- (2008) G. Frey et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An Oxygen Scavenging System for Improvement of Dye Stability in Single-Molecule Fluorescence Experiments
- (2007) Colin Echeverría Aitken et al. BIOPHYSICAL JOURNAL
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started