Antigen modification regulates competition of broad and narrow neutralizing HIV antibodies
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Antigen modification regulates competition of broad and narrow neutralizing HIV antibodies
Authors
Keywords
-
Journal
SCIENCE
Volume 346, Issue 6215, Pages 1380-1383
Publisher
American Association for the Advancement of Science (AAAS)
Online
2014-12-12
DOI
10.1126/science.1259206
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization
- (2013) Florian Klein et al. CELL
- Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies
- (2013) Tongqing Zhou et al. IMMUNITY
- Engineering HIV envelope protein to activate germline B cell receptors of broadly neutralizing anti-CD4 binding site antibodies
- (2013) Andrew T. McGuire et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Germinal center B cells govern their own fate via antibody feedback
- (2013) Yang Zhang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Diverse Recombinant HIV-1 Envs Fail To Activate B Cells Expressing the Germline B Cell Receptors of the Broadly Neutralizing Anti-HIV-1 Antibodies PG9 and 447-52D
- (2013) A. T. McGuire et al. JOURNAL OF VIROLOGY
- Stabilizing Exposure of Conserved Epitopes by Structure Guided Insertion of Disulfide Bond in HIV-1 Envelope Glycoprotein
- (2013) Aemro Kassa et al. PLoS One
- Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer
- (2013) D. Lyumkis et al. SCIENCE
- Antibodies in HIV-1 Vaccine Development and Therapy
- (2013) F. Klein et al. SCIENCE
- Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors
- (2013) J. Jardine et al. SCIENCE
- Recombinant HIV Envelope Proteins Fail to Engage Germline Versions of Anti-CD4bs bNAbs
- (2013) Sam Hoot et al. PLoS Pathogens
- The Effects of Somatic Hypermutation on Neutralization and Binding in the PGT121 Family of Broadly Neutralizing HIV Antibodies
- (2013) Devin Sok et al. PLoS Pathogens
- A Next-Generation Cleaved, Soluble HIV-1 Env Trimer, BG505 SOSIP.664 gp140, Expresses Multiple Epitopes for Broadly Neutralizing but Not Non-Neutralizing Antibodies
- (2013) Rogier W. Sanders et al. PLoS Pathogens
- Germinal Centers
- (2012) Gabriel D. Victora et al. Annual Review of Immunology
- Anti-HIV B Cell Lines as Candidate Vaccine Biosensors
- (2012) T. Ota et al. JOURNAL OF IMMUNOLOGY
- 2G12-Expressing B Cell Lines May Aid in HIV Carbohydrate Vaccine Design Strategies
- (2012) K. J. Doores et al. JOURNAL OF VIROLOGY
- Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies
- (2012) H. Mouquet et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Analysis of a Clonal Lineage of HIV-1 Envelope V2/V3 Conformational Epitope-Specific Broadly Neutralizing Antibodies and Their Inferred Unmutated Common Ancestors
- (2011) M. Bonsignori et al. JOURNAL OF VIROLOGY
- Broad neutralization coverage of HIV by multiple highly potent antibodies
- (2011) Laura M. Walker et al. NATURE
- Memory B Cell Antibodies to HIV-1 gp140 Cloned from Individuals Infected with Clade A and B Viruses
- (2011) Hugo Mouquet et al. PLoS One
- Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing
- (2011) X. Wu et al. SCIENCE
- Increasing the Potency and Breadth of an HIV Antibody by Using Structure-Based Rational Design
- (2011) R. Diskin et al. SCIENCE
- Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding
- (2011) J. F. Scheid et al. SCIENCE
- A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield
- (2011) R. Pejchal et al. SCIENCE
- Envelope Deglycosylation Enhances Antigenicity of HIV-1 gp41 Epitopes for Both Broad Neutralizing Antibodies and Their Unmutated Ancestor Antibodies
- (2011) Ben-Jiang Ma et al. PLoS Pathogens
- Individual Variation in the Germline Ig Gene Repertoire Inferred from Variable Region Gene Rearrangements
- (2010) S. D. Boyd et al. JOURNAL OF IMMUNOLOGY
- Very Few Substitutions in a Germ Line Antibody Are Required To Initiate Significant Domain Exchange
- (2010) Michael Huber et al. JOURNAL OF VIROLOGY
- Crystal Structure of Human Antibody 2909 Reveals Conserved Features of Quaternary Structure-Specific Antibodies That Potently Neutralize HIV-1
- (2010) A. Changela et al. JOURNAL OF VIROLOGY
- Quaternary Epitope Specificities of Anti-HIV-1 Neutralizing Antibodies Generated in Rhesus Macaques Infected by the Simian/Human Immunodeficiency Virus SHIVSF162P4
- (2010) J. E. Robinson et al. JOURNAL OF VIROLOGY
- Development of B-lineage Predominant Lentiviral Vectors for Use in Genetic Therapies for B Cell Disorders
- (2010) Blythe D Sather et al. MOLECULAR THERAPY
- Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01
- (2010) T. Zhou et al. SCIENCE
- Rational Design of Envelope Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1
- (2010) X. Wu et al. SCIENCE
- Germline-like predecessors of broadly neutralizing antibodies lack measurable binding to HIV-1 envelope glycoproteins: Implications for evasion of immune responses and design of vaccine immunogens
- (2009) Xiaodong Xiao et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals
- (2009) Johannes F. Scheid et al. NATURE
- Neutralizing antibodies generated during natural HIV-1 infection: good news for an HIV-1 vaccine?
- (2009) Leonidas Stamatatos et al. NATURE MEDICINE
- Structural Basis of Immune Evasion at the Site of CD4 Attachment on HIV-1 gp120
- (2009) L. Chen et al. SCIENCE
- Broad and Potent Neutralizing Antibodies from an African Donor Reveal a New HIV-1 Vaccine Target
- (2009) L. M. Walker et al. SCIENCE
- Improving the expression of recombinant soluble HIV Envelope glycoproteins using pseudo-stable transient transfection
- (2009) George Sellhorn et al. VACCINE
- Maturation Pathways of Cross-Reactive HIV-1 Neutralizing Antibodies
- (2009) Xiaodong Xiao et al. Viruses-Basel
- IMGT/V-QUEST: the highly customized and integrated system for IG and TR standardized V-J and V-D-J sequence analysis
- (2008) X. Brochet et al. NUCLEIC ACIDS RESEARCH
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started