Complete epitopes for vaccine design derived from a crystal structure of the broadly neutralizing antibodies PGT128 and 8ANC195 in complex with an HIV-1 Env trimer
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Title
Complete epitopes for vaccine design derived from a crystal structure of the broadly neutralizing antibodies PGT128 and 8ANC195 in complex with an HIV-1 Env trimer
Authors
Keywords
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Journal
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
Volume 71, Issue 10, Pages 2099-2108
Publisher
International Union of Crystallography (IUCr)
Online
2015-09-25
DOI
10.1107/s1399004715013917
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Note: Only part of the references are listed.- Crystal structure of a fully glycosylated HIV-1 gp120 core reveals a stabilizing role for the glycan at Asn262
- (2015) Leopold Kong et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
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- (2014) Fernando Garces et al. CELL
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- (2014) Claudia Blattner et al. IMMUNITY
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- (2014) Katie J. Doores et al. JOURNAL OF VIROLOGY
- Broad and potent HIV-1 neutralization by a human antibody that binds the gp41–gp120 interface
- (2014) Jinghe Huang et al. NATURE
- Structure and immune recognition of trimeric pre-fusion HIV-1 Env
- (2014) Marie Pancera et al. NATURE
- Deletion of the Highly Conserved N-Glycan at Asn260 of HIV-1 gp120 Affects Folding and Lysosomal Degradation of gp120, and Results in Loss of Viral Infectivity
- (2014) Leen Mathys et al. PLoS One
- Promiscuous Glycan Site Recognition by Antibodies to the High-Mannose Patch of gp120 Broadens Neutralization of HIV
- (2014) D. Sok et al. Science Translational Medicine
- Antibody 8ANC195 Reveals a Site of Broad Vulnerability on the HIV-1 Envelope Spike
- (2014) Louise Scharf et al. Cell Reports
- Structural basis for diverse N-glycan recognition by HIV-1–neutralizing V1–V2–directed antibody PG16
- (2013) Marie Pancera et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120
- (2013) Leopold Kong et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Crystal Structure of a Soluble Cleaved HIV-1 Envelope Trimer
- (2013) J.-P. Julien et al. SCIENCE
- Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer
- (2013) D. Lyumkis et al. SCIENCE
- Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors
- (2013) J. Jardine et al. SCIENCE
- A Next-Generation Cleaved, Soluble HIV-1 Env Trimer, BG505 SOSIP.664 gp140, Expresses Multiple Epitopes for Broadly Neutralizing but Not Non-Neutralizing Antibodies
- (2013) Rogier W. Sanders et al. PLoS Pathogens
- A Blueprint for HIV Vaccine Discovery
- (2012) Dennis R. Burton et al. Cell Host & Microbe
- Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9
- (2011) Jason S. McLellan et al. NATURE
- Broad neutralization coverage of HIV by multiple highly potent antibodies
- (2011) Laura M. Walker et al. NATURE
- Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding
- (2011) J. F. Scheid et al. SCIENCE
- A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield
- (2011) R. Pejchal et al. SCIENCE
- Features and development ofCoot
- (2010) P. Emsley et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- PHENIX: a comprehensive Python-based system for macromolecular structure solution
- (2010) Paul D. Adams et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- The JCSG high-throughput structural biology pipeline
- (2010) Marc-André Elsliger et al. Acta Crystallographica Section F-Structural Biology and Crystallization Communications
- Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01
- (2010) T. Zhou et al. SCIENCE
- MolProbity: all-atom structure validation for macromolecular crystallography
- (2009) Vincent B. Chen et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Broad and Potent Neutralizing Antibodies from an African Donor Reveal a New HIV-1 Vaccine Target
- (2009) L. M. Walker et al. SCIENCE
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