- Home
- Publications
- Publication Search
- Publication Details
Title
TGR5, Not Only a Metabolic Regulator
Authors
Keywords
-
Journal
Frontiers in Physiology
Volume 7, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2016-12-27
DOI
10.3389/fphys.2016.00646
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Activation of bile acid signaling improves metabolic phenotypes in high-fat diet-induced obese mice
- (2016) Joseph F. Pierre et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- G-protein-coupled bile acid receptor plays a key role in bile acid metabolism and fasting-induced hepatic steatosis in mice
- (2016) Ajay C. Donepudi et al. HEPATOLOGY
- Activation of Transmembrane Bile Acid Receptor TGR5 Modulates Pancreatic Islet α Cells to Promote Glucose Homeostasis
- (2016) Divya P. Kumar et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Plasma membrane-bound G protein-coupled bile acid receptor attenuates liver ischemia/reperfusion injury via the inhibition of toll-like receptor 4 signaling in mice
- (2016) Haojun Yang et al. LIVER TRANSPLANTATION
- Dietary obacunone supplementation stimulates muscle hypertrophy, and suppresses hyperglycemia and obesity through the TGR5 and PPARγ pathway
- (2015) Taro Horiba et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Bile acid signaling and liver regeneration
- (2015) Mingjie Fan et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- The Bile Acid Chenodeoxycholic Acid Increases Human Brown Adipose Tissue Activity
- (2015) Evie P.M. Broeders et al. Cell Metabolism
- The Bile Acid Receptor TGR5 and Liver Regeneration
- (2015) Valeska Jourdainne et al. DIGESTIVE DISEASES
- The role of obesity in atrial fibrillation
- (2015) Chrishan Joseph Nalliah et al. EUROPEAN HEART JOURNAL
- TGR5 is essential for bile acid-dependent cholangiocyte proliferation in vivo and in vitro
- (2015) Maria Reich et al. GUT
- PI3K and AKT: Unfaithful Partners in Cancer
- (2015) Seraina Faes et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- TGR5 signaling reduces neuroinflammation during hepatic encephalopathy
- (2015) Matthew McMillin et al. JOURNAL OF NEUROCHEMISTRY
- G Protein-Coupled Bile Acid Receptor TGR5 Activation Inhibits Kidney Disease in Obesity and Diabetes
- (2015) X. X. Wang et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Natural history of β-cell adaptation and failure in type 2 diabetes
- (2015) Emilyn U. Alejandro et al. MOLECULAR ASPECTS OF MEDICINE
- A Novel TGR5 Activator WB403 Promotes GLP-1 Secretion and Preserves Pancreatic β-Cells in Type 2 Diabetic Mice
- (2015) Chunbing Zheng et al. PLoS One
- Control of macrophage metabolism and activation by mTOR and Akt signaling
- (2015) Anthony J. Covarrubias et al. SEMINARS IN IMMUNOLOGY
- Inhibition of Survival Pathways MAPK and NF-kB Triggers Apoptosis in Pancreatic Ductal Adenocarcinoma Cells via Suppression of Autophagy
- (2015) Daniela Laura Papademetrio et al. Targeted Oncology
- Discovery of a Potent and Orally Efficacious TGR5 Receptor Agonist
- (2015) Sameer Agarwal et al. ACS Medicinal Chemistry Letters
- The G-protein-coupled bile acid receptor Gpbar1 (TGR5) suppresses gastric cancer cell proliferation and migration through antagonizing STAT3 signaling pathway
- (2015) Cong Guo et al. Oncotarget
- The G-Protein-Coupled Bile Acid Receptor Gpbar1 (TGR5) Inhibits Gastric Inflammation Through Antagonizing NF-κB Signaling Pathway
- (2015) Cong Guo et al. Frontiers in Pharmacology
- Bile acids and sphingosine-1-phosphate receptor 2 in hepatic lipid metabolism
- (2015) Eric Kwong et al. Acta Pharmaceutica Sinica B
- STAT3-Mediated Metabolic Reprograming in Cellular Transformation and Implications for Drug Resistance
- (2015) Valeria Poli et al. Frontiers in Oncology
- Molecular classification and prediction in gastric cancer
- (2015) Xiandong Lin et al. Computational and Structural Biotechnology Journal
- Identification of miR-26a as a Target Gene of Bile Acid Receptor GPBAR-1/TGR5
- (2015) Xiaosong Chen et al. PLoS One
- Receptor proximal kinases in NF-κB signaling as potential therapeutic targets in cancer and inflammation
- (2014) Lynn Verstrepen et al. BIOCHEMICAL PHARMACOLOGY
- Extracellular Signal-Regulated Protein Kinases 1 and 2 Activation by Addictive Drugs: A Signal Toward Pathological Adaptation
- (2014) Vincent Pascoli et al. BIOLOGICAL PSYCHIATRY
- Cardiovascular Effects of Intensive Lifestyle Intervention in Type 2 Diabetes
- (2014) Craig A. Johnston et al. Current Atherosclerosis Reports
- STAT3 is a central regulator of lymphocyte differentiation and function
- (2014) Alisa Kane et al. CURRENT OPINION IN IMMUNOLOGY
- MECHANISMS IN ENDOCRINOLOGY: Bile acid sequestrants in type 2 diabetes: potential effects on GLP1 secretion
- (2014) David P Sonne et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
- 4-Benzofuranyloxynicotinamide derivatives are novel potent and orally available TGR5 agonists
- (2014) Qingan Zou et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- The Bile Acid Receptor TGR5 Activates the TRPA1 Channel to Induce Itch in Mice
- (2014) TinaMarie Lieu et al. GASTROENTEROLOGY
- Aberrant DNA Methylation of G-protein-coupled Bile Acid Receptor Gpbar1 (TGR5) is a Potential Biomarker for Hepatitis B Virus Associated Hepatocellular Carcinoma
- (2014) Li-Yan Han et al. International Journal of Medical Sciences
- Significance of AKT in gastric cancer (Review)
- (2014) TAKAMITSU SASAKI et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- TGR5 reduces macrophage migration through mTOR-induced C/EBPβ differential translation
- (2014) Alessia Perino et al. JOURNAL OF CLINICAL INVESTIGATION
- Dietary Substitutions for Refined Carbohydrate That Show Promise for Reducing Risk of Type 2 Diabetes in Men and Women
- (2014) Kevin C Maki et al. JOURNAL OF NUTRITION
- Activation of the bile acid receptor TGR5 enhances LPS-induced inflammatory responses in a human monocytic cell line
- (2014) Kaia Mobraten et al. JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION
- Bile acids are nutrient signaling hormones
- (2014) Huiping Zhou et al. STEROIDS
- Ciliary subcellular localization of TGR5 determines the cholangiocyte functional response to bile acid signaling
- (2013) Anatoliy I. Masyuk et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Bile Acid Receptor TGR5 Agonism Induces NO Production and Reduces Monocyte Adhesion in Vascular Endothelial Cells
- (2013) Taiki Kida et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Design, synthesis and biological evaluation of a novel class of potent TGR5 agonists based on a 4-phenyl pyridine scaffold
- (2013) Junjie Zhu et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- The receptor TGR5 protects the liver from bile acid overload during liver regeneration in mice
- (2013) Noémie Péan et al. HEPATOLOGY
- TGR5 signalling inhibits the production of pro-inflammatory cytokines byin vitrodifferentiated inflammatory and intestinal macrophages in Crohn's disease
- (2013) Kazuaki Yoneno et al. IMMUNOLOGY
- The role of ERK1/2 in the regulation of proliferation and differentiation of astrocytes in developing brain
- (2013) Peipei Cheng et al. INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE
- Regulation of nuclear factor-κB in autoimmunity
- (2013) Shao-Cong Sun et al. TRENDS IN IMMUNOLOGY
- TRC210258, a novel TGR5 agonist, reduces glycemic and dyslipidemic cardiovascular risk in animal models of diabesity
- (2013) Shitalkumar Zambad et al. Diabetes Metabolic Syndrome and Obesity-Targets and Therapy
- Review article: the emerging interplay among the gastrointestinal tract, bile acids and incretins in the pathogenesis of diabetes and non-alcoholic fatty liver disease
- (2012) A. Zarrinpar et al. ALIMENTARY PHARMACOLOGY & THERAPEUTICS
- Activation of G protein-coupled bile acid receptor, TGR5, induces smooth muscle relaxation via both Epac- and PKA-mediated inhibition of RhoA/Rho kinase pathway
- (2012) Senthilkumar Rajagopal et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Activation of transmembrane bile acid receptor TGR5 stimulates insulin secretion in pancreatic β cells
- (2012) Divya P. Kumar et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- NF-κB and the link between inflammation and cancer
- (2012) Joseph A. DiDonato et al. IMMUNOLOGICAL REVIEWS
- Muscarinic receptor agonists stimulate matrix metalloproteinase 1-dependent invasion of human colon cancer cells
- (2011) Jean-Pierre Raufman et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- TGR5 Activation Inhibits Atherosclerosis by Reducing Macrophage Inflammation and Lipid Loading
- (2011) Thijs W.H. Pols et al. Cell Metabolism
- Rap-linked cAMP signaling Epac proteins: Compartmentation, functioning and disease implications
- (2011) Magali Breckler et al. CELLULAR SIGNALLING
- TGR5: A Novel Target for Weight Maintenance and Glucose Metabolism
- (2011) Xiaosong Chen et al. Experimental Diabetes Research
- The G-Protein-coupled bile acid receptor, Gpbar1 (TGR5), negatively regulates hepatic inflammatory response through antagonizing nuclear factor kappa light-chain enhancer of activated B cells (NF-κB) in mice
- (2011) Yan-Dong Wang et al. HEPATOLOGY
- Insufficient bile acid signaling impairs liver repair in CYP27−/− mice
- (2011) Zhipeng Meng et al. JOURNAL OF HEPATOLOGY
- Epac: Defining a New Mechanism for cAMP Action
- (2010) Martijn Gloerich et al. Annual Review of Pharmacology and Toxicology
- TGR5: an emerging bile acid G-protein-coupled receptor target for the potential treatment of metabolic disorders
- (2009) Atul Tiwari et al. DRUG DISCOVERY TODAY
- Role of a novel bile acid receptor TGR5 in the development of oesophageal adenocarcinoma
- (2009) J. Hong et al. GUT
- Farnesoid X receptor alleviates age-related proliferation defects in regenerating mouse livers by activating forkhead box m1b transcription
- (2009) Wei-Dong Chen et al. HEPATOLOGY
- Discovery of 6α-Ethyl-23(S)-methylcholic Acid (S-EMCA, INT-777) as a Potent and Selective Agonist for the TGR5 Receptor, a Novel Target for Diabesity
- (2009) Roberto Pellicciari et al. JOURNAL OF MEDICINAL CHEMISTRY
- Expression and function of the bile acid receptor TGR5 in Kupffer cells
- (2008) Verena Keitel et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- FXR: a metabolic regulator and cell protector
- (2008) Yan-Dong Wang et al. CELL RESEARCH
- Farnesoid X receptor antagonizes nuclear factor κB in hepatic inflammatory response
- (2008) Yan-Dong Wang et al. HEPATOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started