Anti-hypertensive Herbs and their Mechanisms of Action: Part I

Oxidative Stress and Human Hypertension: Vascular Mechanisms, Biomarkers, and Novel Therapies

(2015) Augusto C. Montezano et al.   CANADIAN JOURNAL OF CARDIOLOGY

Chronic NF-κB blockade improves renal angiotensin II type 1 receptor functions and reduces blood pressure in Zucker diabetic rats

(2015) Hao Luo et al.   Cardiovascular Diabetology

Effect of Garlic on Blood Pressure: A Meta-Analysis

(2015) Hai-Peng Wang et al.   Journal of Clinical Hypertension

Meta-analysis of the effect and safety of berberine in the treatment of type 2 diabetes mellitus, hyperlipemia and hypertension

(2015) Jiarong Lan et al.   JOURNAL OF ETHNOPHARMACOLOGY

Hypertension-attributed nephropathy: what's in a name?

(2015) Barry I. Freedman et al.   Nature Reviews Nephrology

Blood Pressure Lowering Effect of Korea Ginseng Derived Ginseol K-g1

(2014) Moo-Yong Rhee et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Vascular oxidative stress upregulates angiotensin II type I receptors via mechanisms involving nuclear factor kappa B

(2014) Siddhartha R. Bhatt et al.   CLINICAL AND EXPERIMENTAL HYPERTENSION

Ginsenoside Rg1 regulates innate immune responses in macrophages through differentially modulating the NF-κB and PI3K/Akt/mTOR pathways

(2014) Yao Wang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Inhibition of Angiotensin-1-Converting Enzyme Activity by Two Varieties of Ginger (Zingiber officinale) in Rats Fed a High Cholesterol Diet

(2014) Ayodele Jacob Akinyemi et al.   JOURNAL OF MEDICINAL FOOD

Effect of Rg3-enriched Korean red ginseng (Panax ginseng) on arterial stiffness and blood pressure in healthy individuals: a randomized controlled trial

(2014) Elena Jovanovski et al.   Journal of the American Society of Hypertension

Epigallocatechin Gallate Attenuates Proliferation and Oxidative Stress in Human Vascular Smooth Muscle Cells Induced by Interleukin-1βvia Heme Oxygenase-1

(2014) Po-Len Liu et al.   MEDIATORS OF INFLAMMATION

Mechanisms underlying the antihypertensive effects of garlic bioactives

(2014) Reem Shouk et al.   NUTRITION RESEARCH

Garlic Attenuates Cardiac Oxidative Stress via Activation of PI3K/AKT/Nrf2-Keap1 Pathway in Fructose-Fed Diabetic Rat

(2014) Raju Padiya et al.   PLoS One

Ginsenoside Rb3 Protects Cardiomyocytes against Ischemia-Reperfusion Injury via the Inhibition of JNK-Mediated NF-κB Pathway: A Mouse Cardiomyocyte Model

(2014) Lijia Ma et al.   PLoS One

Effect of green tea consumption on blood pressure: A meta-analysis of 13 randomized controlled trials

(2014) Xiaoli Peng et al.   Scientific Reports

Endothelium-Independent Vasorelaxant Effects of Hydroalcoholic Extract fromNigella sativaSeed in Rat Aorta: The Roles of Ca2+and K+Channels

(2014) Saeed Niazmand et al.   Biomed Research International

Ginseng Treatment Attenuates Chronic Cyclosporine Nephropathy via Reducing Oxidative Stress in an Experimental Mouse Model

(2013) Kyoung Chan Doh et al.   AMERICAN JOURNAL OF NEPHROLOGY

Tanshinone I Activates the Nrf2-Dependent Antioxidant Response and Protects Against As(III)-Induced Lung Inflammation In Vitro and In Vivo

(2013) Shasha Tao et al.   ANTIOXIDANTS & REDOX SIGNALING

Reactive Oxygen Species, Vascular Noxs, and Hypertension: Focus on Translational and Clinical Research

(2013) Augusto C. Montezano et al.   ANTIOXIDANTS & REDOX SIGNALING

Thymoquinone inhibits phorbol ester-induced activation of NF-κB and expression of COX-2, and induces expression of cytoprotective enzymes in mouse skin in vivo

(2013) Joydeb Kumar Kundu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

New Perspectives on How to Discover Drugs from Herbal Medicines: CAM's Outstanding Contribution to Modern Therapeutics

(2013) Si-Yuan Pan et al.   Evidence-based Complementary and Alternative Medicine

Nigella sativaand Its Protective Role in Oxidative Stress and Hypertension

(2013) Xin-Fang Leong et al.   Evidence-based Complementary and Alternative Medicine

Trends in the Treatment of Hypertension from the Perspective of Traditional Chinese Medicine

(2013) Xingjiang Xiong et al.   Evidence-based Complementary and Alternative Medicine

Role of Garlic Usage in Cardiovascular Disease Prevention: An Evidence-Based Approach

(2013) Waris Qidwai et al.   Evidence-based Complementary and Alternative Medicine

Bidens pilosaL. (Asteraceae): Botanical Properties, Traditional Uses, Phytochemistry, and Pharmacology

(2013) Arlene P. Bartolome et al.   Evidence-based Complementary and Alternative Medicine

Therapeutic Effects of Water Soluble Danshen Extracts on Atherosclerosis

(2013) Yoon Hee Cho et al.   Evidence-based Complementary and Alternative Medicine

Hibiscus sabdariffa L. in the treatment of hypertension and hyperlipidemia: A comprehensive review of animal and human studies

(2013) Allison L. Hopkins et al.   FITOTERAPIA

Protective effect of extract of Crataegus pinnatifida pollen on DNA damage response to oxidative stress

(2013) Ni Cheng et al.   FOOD AND CHEMICAL TOXICOLOGY

Regulation of Nrf2—an update

(2013) Suryakant K. Niture et al.   FREE RADICAL BIOLOGY AND MEDICINE

2014 Evidence-Based Guideline for the Management of High Blood Pressure in Adults

(2013) Paul A. James et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Anti-inflammatory activity of Cymbopogon citratus leaves infusion via proteasome and nuclear factor-κB pathway inhibition: Contribution of chlorogenic acid

(2013) Vera Francisco et al.   JOURNAL OF ETHNOPHARMACOLOGY

Effect of American ginseng (Panax quinquefolius L.) on arterial stiffness in subjects with type-2 diabetes and concomitant hypertension

(2013) Iva Mucalo et al.   JOURNAL OF ETHNOPHARMACOLOGY

Clinical Practice Guidelines for the Management of Hypertension in the Community A Statement by the American Society of Hypertension and the International Society of Hypertension

(2013) Michael A. Weber et al.   JOURNAL OF HYPERTENSION

Antihypertensive Effect of Celery Seed on Rat Blood Pressure in Chronic Administration

(2013) Maryam Hassanpour Moghadam et al.   JOURNAL OF MEDICINAL FOOD

Aqueous Extracts of Two Varieties of Ginger (Zingiber officinale) Inhibit Angiotensin I–Converting Enzyme, Iron(II), and Sodium Nitroprusside-Induced Lipid Peroxidation in the Rat Heart In Vitro

(2013) Ayodele J. Akinyemi et al.   JOURNAL OF MEDICINAL FOOD

Green tea diet decreases PCB 126-induced oxidative stress in mice by up-regulating antioxidant enzymes

(2013) Bradley J. Newsome et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

USP15 Negatively Regulates Nrf2 through Deubiquitination of Keap1

(2013) Nicole F. Villeneuve et al.   MOLECULAR CELL

Cognitive-enhancing and antioxidant activities of inhaled coriander volatile oil in amyloid β(1–42) rat model of Alzheimer's disease

(2013) Oana Cioanca et al.   PHYSIOLOGY & BEHAVIOR

Blood Pressure Lowering Effect ofNigella sativaL. Seed Oil in Healthy Volunteers: A Randomized, Double-Blind, Placebo-controlled Clinical Trial

(2013) H. Fallah Huseini et al.   PHYTOTHERAPY RESEARCH

[6]-Gingerol: A Novel AT1 Antagonist for the Treatment of Cardiovascular Disease

(2013) Qing Liu et al.   PLANTA MEDICA

Involvement of Rab28 in NF-κB Nuclear Transport in Endothelial Cells

(2013) Jun Jiang et al.   PLoS One

Salvianolic Acid A, a Novel Matrix Metalloproteinase-9 Inhibitor, Prevents Cardiac Remodeling in Spontaneously Hypertensive Rats

(2013) Baohong Jiang et al.   PLoS One

Berberine Ameliorates Chronic Kidney Injury Caused by Atherosclerotic Renovascular Disease through the Suppression of NFκB Signaling Pathway in Rats

(2013) Xin Wan et al.   PLoS One

Ginseng for Health Care: A Systematic Review of Randomized Controlled Trials in Korean Literature

(2013) Jiae Choi et al.   PLoS One

Protective effect ofCymbopogon citratuson hydrogen peroxide-induced oxidative stress in the reproductive system of male rats

(2013) Saleh M. Rahim et al.   Systems Biology in Reproductive Medicine

Antioxidant and anti–glycation activities correlates with phenolic composition of tropical medicinal herbs

(2013) JS Ramkissoon et al.   Asian Pacific Journal of Tropical Medicine

AMP-activated protein kinase inhibits vascular smooth muscle cell proliferation and migration and vascular remodeling following injury

(2012) Joshua D. Stone et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Hydrogen Sulfide in the Mammalian Cardiovascular System

(2012) Yi-Hong Liu et al.   ANTIOXIDANTS & REDOX SIGNALING

Effects of Black Tea on Blood Pressure: A Randomized Controlled Trial

(2012) Jonathan M. Hodgson   ARCHIVES OF INTERNAL MEDICINE

Effect of hawthorn standardized extract on flow mediated dilation in prehypertensive and mildly hypertensive adults: a randomized, controlled cross-over trial

(2012) Gary N Asher et al.   BMC Complementary and Alternative Medicine

The vascular smooth muscle cell in arterial pathology: a cell that can take on multiple roles

(2012) P. Lacolley et al.   CARDIOVASCULAR RESEARCH

Uncoupling Endothelial Nitric Oxide Synthase Is Ameliorated by Green Tea in Experimental Diabetes by Re-establishing Tetrahydrobiopterin Levels

(2012) A. M. Faria et al.   DIABETES

Crocin “saffron” protects against beryllium chloride toxicity in rats through diminution of oxidative stress and enhancing gene expression of antioxidant enzymes

(2012) Hesham A. El-Beshbishy et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Aged garlic extract reduces blood pressure in hypertensives: a dose–response trial

(2012) K Ried et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Salvianolic acid B possesses vasodilation potential through NO and its related signals in rabbit thoracic aortic rings

(2012) Qiyang Shou et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Green Tea Attenuates Oxidative Stress and Downregulates the Expression of Angiotensin II AT1Receptor in Renal and Hepatic Tissues of Streptozotocin-Induced Diabetic Rats

(2012) Martha Thomson et al.   Evidence-based Complementary and Alternative Medicine

Outcome Measures of Chinese Herbal Medicine for Hypertension: An Overview of Systematic Reviews

(2012) Jie Wang et al.   Evidence-based Complementary and Alternative Medicine

Effect ofCymbopogon citratusand Citral on Vascular Smooth Muscle of the Isolated Thoracic Rat Aorta

(2012) R. Chitra Devi et al.   Evidence-based Complementary and Alternative Medicine

Long-term ingestion of Hibiscus sabdariffa calyx extract enhances myocardial capillarization in the spontaneously hypertensive rat

(2012) Ibrahim Inuwa et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Cardio protective effect of Coriandrum sativum L. on isoproterenol induced myocardial necrosis in rats

(2012) Dipak K. Patel et al.   FOOD AND CHEMICAL TOXICOLOGY

Regulation of NAD(P)H oxidases by AMPK in cardiovascular systems

(2012) Ping Song et al.   FREE RADICAL BIOLOGY AND MEDICINE

Panax ginseng Extract Rich in Ginsenoside Protopanaxatriol Attenuates Blood Pressure Elevation in Spontaneously Hypertensive Rats by Affecting the Akt-Dependent Phosphorylation of Endothelial Nitric Oxide Synthase

(2012) So Young Hong et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Cardiovascular Activity of Labdane Diterpenes fromAndrographis paniculatain Isolated Rat Hearts

(2012) Khalijah Awang et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Natural Products As Sources of New Drugs over the 30 Years from 1981 to 2010

(2012) David J. Newman et al.   JOURNAL OF NATURAL PRODUCTS

Consumption of Hibiscus sabdariffa L. aqueous extract and its impact on systemic antioxidant potential in healthy subjects

(2012) Thomas Frank et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Composition and health effects of phenolic compounds in hawthorn (Crataegus spp.) of different origins

(2012) Baoru Yang et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Red Ginseng Marc Oil Inhibits iNOS and COX-2 via NFκB and p38 Pathways in LPS-Stimulated RAW 264.7 Macrophages

(2012) Min-Ji Bak et al.   MOLECULES

Green tea extract reduces blood pressure, inflammatory biomarkers, and oxidative stress and improves parameters associated with insulin resistance in obese, hypertensive patients

(2012) Pawel Bogdanski et al.   NUTRITION RESEARCH

Activation of IKK/NF-κB provokes renal inflammatory responses in guanylyl cyclase/natriuretic peptide receptor-A gene-knockout mice

(2012) Subhankar Das et al.   PHYSIOLOGICAL GENOMICS

Involvements of calcium channel and potassium channel in Danshen and Gegen decoction induced vasodilation in porcine coronary LAD artery

(2012) Fan Hu et al.   PHYTOMEDICINE

Effects ofCrataegus microphyllaon Vascular Dysfunction in Streptozotocin-induced Diabetic Rats

(2012) Gökçe Topal et al.   PHYTOTHERAPY RESEARCH

An Extract of Crataegus pinnatifida Fruit Attenuates Airway Inflammation by Modulation of Matrix Metalloproteinase-9 in Ovalbumin Induced Asthma

(2012) In Sik Shin et al.   PLoS One

cGMP-Dependent Protein Kinase Contributes to Hydrogen Sulfide-Stimulated Vasorelaxation

(2012) Mariarosaria Bucci et al.   PLoS One

The Relaxant Effect of Ginseng Saponin on the Bladder and Prostatic Urethra: An in vitro and in vivo Study

(2012) H.A. Jang et al.   UROLOGIA INTERNATIONALIS

Therapeutic Potential of Quercetin to Decrease Blood Pressure: Review of Efficacy and Mechanisms

(2012) Abigail J. Larson et al.   Advances in Nutrition

Cardiovascular Diseases and Panax ginseng: A Review on Molecular Mechanisms and Medical Applications

(2012) Jong-Hoon Kim   Journal of Ginseng Research

Control of Vascular Smooth Muscle Cell Growth by Connexin 43

(2012) Chintamani N. Joshi et al.   Frontiers in Physiology

Contribution of oxidative stress to endothelial dysfunction in hypertension

(2012) Bruno R. Silva et al.   Frontiers in Physiology

Tanshinone IIA Inhibits Angiotensin II-Induced Cell Proliferation in Rat Cardiac Fibroblasts

(2011) Paul Chan et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Role of Cystathionine γ-Lyase/Hydrogen Sulfide Pathway in Cardiovascular Disease: A Novel Therapeutic Strategy?

(2011) Li Long Pan et al.   ANTIOXIDANTS & REDOX SIGNALING

Reactive Oxygen Species and Endothelial Function - Role of Nitric Oxide Synthase Uncoupling and Nox Family Nicotinamide Adenine Dinucleotide Phosphate Oxidases

(2011) Augusto C. Montezano et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

The role of perivascular adipose tissue in vascular smooth muscle cell growth

(2011) Chao-Yu Miao et al.   BRITISH JOURNAL OF PHARMACOLOGY

Vascular Smooth Muscle Cell Proliferation in Restenosis

(2011) Steven O. Marx et al.   Circulation-Cardiovascular Interventions

Chemopreventive Properties and Molecular Mechanisms of the Bioactive Compounds in Hibiscus Sabdariffa Linne

(2011) Hui-Hsuan Lin et al.   CURRENT MEDICINAL CHEMISTRY

Antioxidant and drug detoxification potentials ofHibiscus sabdariffaanthocyanin extract

(2011) Taofeek O. Ajiboye et al.   DRUG AND CHEMICAL TOXICOLOGY

How Do Glucocorticoids Cause Hypertension: Role of Nitric Oxide Deficiency, Oxidative Stress, and Eicosanoids

(2011) Sharon L.H. Ong et al.   ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA

Akt/GSK-3β/eNOS phosphorylation arbitrates safranal-induced myocardial protection against ischemia–reperfusion injury in rats

(2011) Saurabh Bharti et al.   EUROPEAN JOURNAL OF NUTRITION

Angiotensin II and the vascular phenotype in hypertension

(2011) Carmine Savoia et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Antioxidant potential of Cymbopogon citratus extract: alleviation of carbon tetrachloride-induced hepatic oxidative stress and toxicity

(2011) Pei Hoon Koh et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

The anti-hypertensive effect of Danshen (Salvia miltiorrhiza) and Gegen (Pueraria lobata) formula in rats and its underlying mechanisms of vasorelaxation

(2011) C.F. Ng et al.   JOURNAL OF ETHNOPHARMACOLOGY

Pharmacological characterization of the diuretic effect of Hibiscus sabdariffa Linn (Malvaceae) extract

(2011) Javier Alarcón-Alonso et al.   JOURNAL OF ETHNOPHARMACOLOGY

Effects and mechanisms of totalPanax notoginsengsaponins on proliferation of vascular smooth muscle cells with plasma pharmacology method

(2011) Wei Zhang et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets

(2011) Grant R. Drummond et al.   NATURE REVIEWS DRUG DISCOVERY

A new look at the renin–angiotensin system—Focusing on the vascular system

(2011) Aurelie Nguyen Dinh Cat et al.   PEPTIDES

Tea and cardiovascular disease

(2011) Apranta Deka et al.   PHARMACOLOGICAL RESEARCH

Effect of Salvia miltiorrhiza Hydrophilic Extract on Antioxidant Enzymes in Diabetic Patients with Chronic Heart Disease: A Randomized Controlled Trial

(2011) Qingwen Qian et al.   PHYTOTHERAPY RESEARCH

Aged Garlic Extract Scavenges Superoxide Radicals

(2011) Naoaki Morihara et al.   PLANT FOODS FOR HUMAN NUTRITION

Tea Consumption Enhances Endothelial-Dependent Vasodilation; a Meta-Analysis

(2011) Rouyanne T. Ras et al.   PLoS One

Traditional herbal medicine in Far-west Nepal: a pharmacological appraisal

(2011) Ripu M Kunwar et al.   Journal of Ethnobiology and Ethnomedicine

Inhibitory Effects of Total Ginseng Saponin on Catecholamine Secretion from the Perfused Adrenal Medulla of SHRs

(2011) Seok-Jeong Jang et al.   Journal of Ginseng Research

Hypotensive and Vasorelaxant Effects of Citronellol, a Monoterpene Alcohol, in Rats

(2010) Joana F. A. Bastos et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Renin-angiotensin-aldosterone system blockade for cardiovascular diseases: current status

(2010) Terry KW Ma et al.   BRITISH JOURNAL OF PHARMACOLOGY

Natural Antioxidants and Hypertension: Promise and Challenges

(2010) Tinoy J. Kizhakekuttu et al.   Cardiovascular Therapeutics

Green Tea Catechins Improve Human Forearm Endothelial Dysfunction and Have Antiatherosclerotic Effects in Smokers

(2010) Jun-ichi Oyama et al.   CIRCULATION JOURNAL

Vascular Endothelial Function and Hypertension: Insights and Directions

(2010) Kodlipet Dharmashankar et al.   CURRENT HYPERTENSION REPORTS

Anti-inflammatory effects of crocin and crocetin in rat brain microglial cells

(2010) Kyong Nyon Nam et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Suppression of oxidative stress and pro-inflammatory mediators by Cymbopogon citratus D. Stapf extract in lipopolysaccharide stimulated murine alveolar macrophages

(2010) M. Tiwari et al.   FOOD AND CHEMICAL TOXICOLOGY

Mechanisms of the relaxant effect of a Danshen and Gegen formulation on rat isolated cerebral basilar artery

(2010) F.F.Y. Lam et al.   JOURNAL OF ETHNOPHARMACOLOGY

Anti-Inflammatory Activity of Cymbopogon citratus Leaf Infusion in Lipopolysaccharide-Stimulated Dendritic Cells: Contribution of the Polyphenols

(2010) Artur Figueirinha et al.   JOURNAL OF MEDICINAL FOOD

Use of Herbal Products and Potential Interactions in Patients With Cardiovascular Diseases

(2010) Ara Tachjian et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Suppressive effects of extracts from the aerial part of Coriandrum sativum L. on LPS-induced inflammatory responses in murine RAW 264.7 macrophages

(2010) Trang-Tiau Wu et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Aged garlic extract lowers blood pressure in patients with treated but uncontrolled hypertension: A randomised controlled trial

(2010) Karin Ried et al.   MATURITAS

Cellular signaling and NO production

(2010) Thomas Michel et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Olive (Olea europaea) leaf extract effective in patients with stage-1 hypertension: Comparison with Captopril

(2010) Endang Susalit et al.   PHYTOMEDICINE

Novel Insights Into Hydrogen Sulfide–Mediated Cytoprotection

(2009) John W. Calvert et al.   ANTIOXIDANTS & REDOX SIGNALING

Berberine prevents hyperglycemia-induced endothelial injury and enhances vasodilatation via adenosine monophosphate-activated protein kinase and endothelial nitric oxide synthase

(2009) Yiqun Wang et al.   CARDIOVASCULAR RESEARCH

Brain nuclear factor-kappa B activation contributes to neurohumoral excitation in angiotensin II-induced hypertension

(2009) Y.-M. Kang et al.   CARDIOVASCULAR RESEARCH

Reactive Oxygen Species and Dopamine Receptor Function in Essential Hypertension

(2009) Chunyu Zeng et al.   CLINICAL AND EXPERIMENTAL HYPERTENSION

Role of TNF-α in vascular dysfunction

(2009) Hanrui Zhang et al.   CLINICAL SCIENCE

Nuclear factor-κB as a hormonal intracellular signaling molecule: focus on angiotensin II-induced cardiovascular and renal injury

(2009) Xiao C Li et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Alternative and Complementary Medicine for Preventing and Treating Cardiovascular Disease

(2009) William H. Frishman et al.   DM DISEASE-A-MONTH

Garlic Increases Antioxidant Levels in Diabetic and Hypertensive Rats Determined by a Modified Peroxidase Method

(2009) Hana Drobiova et al.   Evidence-based Complementary and Alternative Medicine

Crataegus Special Extract WS 1442 Causes Endothelium-dependent Relaxation via a Redox-sensitive Src- and Akt-dependent Activation of Endothelial NO Synthase but Not via Activation of Estrogen Receptors

(2009) Eric Anselm et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Ginsenoside Rg1 protects rat cardiomyocyte from hypoxia/reoxygenation oxidative injury via antioxidant and intracellular calcium homeostasis

(2009) Dan Zhu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Inhibition of angiotensin convertin enzyme (ACE) activity by the anthocyanins delphinidin- and cyanidin-3-O-sambubiosides from Hibiscus sabdariffa

(2009) Deyanira Ojeda et al.   JOURNAL OF ETHNOPHARMACOLOGY

Hibiscus Sabdariffa L. Tea (Tisane) Lowers Blood Pressure in Prehypertensive and Mildly Hypertensive Adults

(2009) Diane L. McKay et al.   JOURNAL OF NUTRITION

Neuroprotective Effects of Garlic: A Review

(2009) B Mathew et al.   Libyan Journal of Medicine

The Renin Angiotensin Aldosterone System in Hypertension: Roles of Insulin Resistance and Oxidative Stress

(2009) Camila Manrique et al.   MEDICAL CLINICS OF NORTH AMERICA

Garlic components inhibit angiotensin II-induced cell-cycle progression and migration: Involvement of cell-cycle inhibitor p27Kip1 and mitogen-activated protein kinase

(2009) Claudia Castro et al.   MOLECULAR NUTRITION & FOOD RESEARCH

In vitro vasorelaxation mechanisms of bioactive compounds extracted from Hibiscus sabdariffa on rat thoracic aorta

(2009) Mamadou Sarr et al.   Nutrition & Metabolism

Hypotensive effect of aqueous saffron extract (Crocus sativus L.) and its constituents, safranal and crocin, in normotensive and hypertensive rats

(2009) Mohsen Imenshahidi et al.   PHYTOTHERAPY RESEARCH

Inhibitory effect of citral on NO production by suppression of iNOS expression and NF-κB activation in RAW264.7 cells

(2008) Hwa Jeong Lee et al.   ARCHIVES OF PHARMACAL RESEARCH

Effect of garlic on blood pressure: A systematic review and meta-analysis

(2008) Karin Ried et al.   BMC Cardiovascular Disorders

Green Tea Catechins and Cardiovascular Health: An Update

(2008) Pon Anandh Babu et al.   CURRENT MEDICINAL CHEMISTRY

Protective effects of Coriandrum sativum extracts on carbon tetrachloride-induced hepatotoxicity in rats

(2008) S. Sreelatha et al.   FOOD AND CHEMICAL TOXICOLOGY

Antihypertensive effect ofNigella sativaseed extract in patients with mild hypertension

(2008) Farshad Roghani Dehkordi et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Dihydrotanshinone, a lipophilic component of Salvia miltiorrhiza (danshen), relaxes rat coronary artery by inhibition of calcium channels

(2008) Francis F.Y. Lam et al.   JOURNAL OF ETHNOPHARMACOLOGY

Coriander fruit exhibits gut modulatory, blood pressure lowering and diuretic activities

(2008) Qaiser Jabeen et al.   JOURNAL OF ETHNOPHARMACOLOGY

The effects of sour tea (Hibiscus sabdariffa) on hypertension in patients with type II diabetes

(2008) H Mozaffari-Khosravi et al.   JOURNAL OF HUMAN HYPERTENSION

Green tea (Camellia sinensis) Attenuates Nephropathy by Downregulating Nox4 NADPH Oxidase in Diabetic Spontaneously Hypertensive Rats

(2008) Pérola D. B. Ribaldo et al.   JOURNAL OF NUTRITION

Safety evaluation of saffron (Crocus sativus) tablets in healthy volunteers

(2008) Mohammad-Hadi Modaghegh et al.   PHYTOMEDICINE

Effect of aqueous-ethanol extract fromCrocus sativus (saffron) on guinea-pig isolated heart

(2007) M. H. Boskabady et al.   PHYTOTHERAPY RESEARCH