Article
Biotechnology & Applied Microbiology
Alexandra Dimofte, Natalia Simionescu, Anca-Roxana Petrovici, Iuliana Spiridon
Summary: This study successfully increased the exopolysaccharide (EPS) yield of Weissella confusa strain by adding different concentrations of anthocyanin from Hibiscus sabdariffa L. The anthocyanin also protected the strain cells against low pH and bile salt.
FERMENTATION-BASEL
(2022)
Article
Chemistry, Applied
Jian Ai, Qixia Wu, Maurizio Battino, Weibin Bai, Lingmin Tian
Summary: This study utilized UHPLC-QE-MS approach with multivariate statistical analyses to investigate the metabolic profiles, particularly anthocyanin profiles, during roselle wine fermentation. A variety of metabolites including anthocyanins were identified, with several metabolic pathways related to flavonoid and anthocyanin biosynthesis identified during the fermentation process. These findings will be beneficial for future research in wine chemistry and yeast metabolism.
Article
Biochemistry & Molecular Biology
Alessio Malacrida, Valeria Cavalloro, Emanuela Martino, Giosue Costa, Francesca Alessandra Ambrosio, Stefano Alcaro, Roberta Rigolio, Arianna Cassetti, Mariarosaria Miloso, Simona Collina
Summary: The study found that the Hibiscus sabdariffa hydroalcoholic extract containing Hib-ester and Hib-carbaldehyde can inhibit the growth of multiple myeloma cells, showing potential as an anticancer drug. These compounds exhibit good interaction with proteasome, and the presence of anthocyanins in the extract also contributes to proteasome inhibition.
Article
Pharmacology & Pharmacy
Mohd Aftab Alam, Yousef A. Bin Jardan, Bader Alzenaidy, Mohammad Raish, Abdullah M. Al-Mohizea, Abdul Ahad, Fahad Ibrahim Al-Jenoobi
Summary: Ginger and hibiscus can lower blood pressure, and when used in combination with amlodipine, they can further reduce blood pressure effectively. These herbs also affect the blood concentration and peak time of amlodipine.
JOURNAL OF PHARMACY AND PHARMACOLOGY
(2021)
Review
Nutrition & Dietetics
Lucy R. Ellis, Sadia Zulfiqar, Mel Holmes, Lisa Marshall, Louise Dye, Christine Boesch
Summary: This review examines the effectiveness of hibiscus in modulating cardiovascular disease risk markers and finds that hibiscus has significant effects in reducing systolic blood pressure and low-density lipoprotein levels.
Article
Multidisciplinary Sciences
Di Liu, Zheli Ding, Esmat F. Ali, Ahmed M. S. Kheir, Mamdouh A. Eissa, Omer H. M. Ibrahim
Summary: The addition of biochar and compost significantly improved soil quality and nutrient availability under saline irrigation, leading to enhanced growth and yield of roselle plants. Mixing biochar and compost showed superior results compared to individual application of each amendment, suggesting the recommendation of their combined use for roselle plants irrigated with saline water.
SCIENTIFIC REPORTS
(2021)
Article
Engineering, Chemical
Dwila Nur Rizkiyah, Nicky Rahmana Putra, Zuhaili Idham, Ahmad Hazim Abdul Aziz, Mohd Azizi Che Yunus, Ibham Veza, Irianto, Stanley Chinedu Mamah, Lailatul Qomariyah
Summary: A combination of supercritical carbon dioxide (ScCO2) and subcritical water extraction (SWE) was used to extract anthocyanins from roselle. The results showed that this integrated approach achieved higher anthocyanins production and yield compared to previous methods.
Article
Plant Sciences
Gerardo Lorenzana-Martinez, Cesar Alejandro San Juan-Garcia, Anne Santerre, Isaac Andrade-Gonzalez, Jacinto Banuelos-Pineda
Summary: The calyxes of Hibiscus sabdariffa have multiple pharmacological effects due to their high anthocyanin content. However, their phytoestrogenic effect is not well understood. Ovarian hypofunction (OH) is characterized by a rapid decline in ovarian hormone production, which affects reproductive and cognitive functions. Hormone replacement therapy (HRT) effectively compensates for OH, but concerns about its secondary effects and safety have been raised. One possible alternative to HRT is using phytoestrogens like anthocyanins. Recent research on a rat model showed that an anthocyanin-rich extract from H. sabdariffa calyxes improved memory performance and had a potential phytoestrogenic impact through the modulation of estrogen receptor expression. The study suggests further exploration of H. sabdariffa as a nutrition-based alternative to HRT.
PLANT FOODS FOR HUMAN NUTRITION
(2023)
Article
Biochemistry & Molecular Biology
Duanyang Wang, Maki Nagata, Masako Matsumoto, Yhiya Amen, Dongmei Wang, Kuniyoshi Shimizu
Summary: This study evaluated the bioactivities of different parts of Hibiscus sabdariffa L. and found that hibiscus acid has the potential to promote extracellular matrix synthesis, exhibit anti-inflammatory activity, and counter oxidative stress.
Review
Nutrition & Dietetics
Stefano Vendrame, Tolu Esther Adekeye, Dorothy Klimis-Zacas
Summary: There is a relationship between the consumption of dietary berries and blood pressure reduction, with some specific types of berries indirectly normalizing blood pressure in subjects that are already hypertensive.
Article
Food Science & Technology
Carolina Moser Paraiso, Jaqueline Gilmara Barboza Januario, Amanda Gouveia Mizuta, Suelen Siqueira dos Santos, Thiago Ferreira dos Santos Magon, Camilla Yara Langer Ogawa, Joao Vitor de Oliveira Silva, Francielle Sato, Jesui Vergilio Visentainer, Jane Martha Graton Mikcha, Grasiele Scaramal Madrona
Summary: The study found that hot infusion of hibiscus tea is more effective in extracting bioactive compounds and antioxidants. The tea provides more antioxidants when prepared in hot conditions and consumed after cooling. It is recommended to consume prepared hibiscus tea within 24 hours, whether hot or cold.
JOURNAL OF FOOD MEASUREMENT AND CHARACTERIZATION
(2021)
Article
Nutrition & Dietetics
Andressa Ladeira Bernardes, Luis Fernando de Sousa Moraes, Bruna Cristina dos Santos Cruz, Lisiane Lopes da Conceicao, Leandro Licursi de Oliveira, Mariaurea Matias Sarandy, Reggiani Vilela Goncalves, Maria do Carmo Gouveia Peluzio
Summary: This study investigates the effects of supplementation with 5% and 10% dehydrated H. sabdariffa calyces (DHSC) on the development of pre-neoplastic lesions in mice. The results show that DHSC supplementation can reduce the formation of aberrant crypt foci (ACF) and have positive effects on liver enzyme activity and colon mucosa inflammation.
BRITISH JOURNAL OF NUTRITION
(2023)
Article
Pharmacology & Pharmacy
Mohamed A. Salem, Shahira M. Ezzat, Kawkab A. Ahmed, Saleh Alseekh, Alisdair R. Fernie, Reham M. Essam
Summary: This study aims to determine the best water extraction method for the antihypertensive metabolites of H. sabdariffa and confirm their in vivo antihypertensive capabilities. The results show that both hot and cold water extracts can reduce levels of angiotensin II, ACE, and aldosterone in the plasma.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Plant Sciences
Marwah Al-Anbaki, Anne-Laure Cavin, Renata Campos Nogueira, Jaafar Taslimi, Hayder Ali, Mohammed Najem, Mustafa Shukur Mahmood, Ibrahim Abdullah Khaleel, Abdulqader Saad Mohammed, Hasan Ramadhan Hasan, Laurence Marcourt, Fabien Felix, Nicolas Vinh Tri Low-Ders, Emerson Ferreira Queiroz, Jean-Luc Wolfender, Marie Watissee, Bertrand Graz
Summary: The study evaluated the feasibility of using Hibiscus sabdariffa decoction to control hypertension in displaced persons in Iraq. Results showed a significant reduction in blood pressure for participants in the intervention group compared to the control group, indicating the potential effectiveness of hibiscus decoction in managing hypertension.
Article
Chemistry, Applied
Caroline Maria Calliari, Marianne Ayumi Shirai, Alessandro Alberto Casazza, Margherita Pettinato, Patrizia Perego
Summary: This work aimed to optimize the obtention of microcapsules of Hibiscus sabdariffa L. tea by spray-drying, using inulin as a carrier agent. The effects of inlet temperature, feed flow rate, and inulin concentration were evaluated. It was possible to obtain pale-rose, slightly sweet instant powders with good total polyphenol content and anthocyanins encapsulation efficiency, indicating physico-chemical and microbiological stability of the microcapsules. The optimum conditions were found to be 5 g L-1 of inulin, inlet temperature of 170°C, and feed flow rate of 83 mL min(-1).
NATURAL PRODUCT RESEARCH
(2023)