Angiotensin II and the vascular phenotype in hypertension

Endothelial progenitor cells: novel biomarker and promising cell therapy for cardiovascular disease

(2015) Shaundeep Sen et al.   CLINICAL SCIENCE

Immune regulation and vascular inflammation in genetic hypertension

(2010) Emilie C. Viel et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Transgenic mice expressing an intracellular fluorescent fusion of angiotensin II demonstrate renal thrombotic microangiopathy and elevated blood pressure

(2010) K. M. Redding et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Reduction of fibrosis-related arrhythmias by chronic renin-angiotensin-aldosterone system inhibitors in an aged mouse model

(2010) Mera Stein et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Upregulation of Nox1 in vascular smooth muscle leads to impaired endothelium-dependent relaxation via eNOS uncoupling

(2010) Anna E. Dikalova et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The (pro)renin receptor in health and disease

(2010) Genevieve Nguyen   ANNALS OF MEDICINE

Tissue Renin-Angiotensin-Aldosterone Systems: Targets for Pharmacological Therapy

(2010) Michael Bader   Annual Review of Pharmacology and Toxicology

Regulation of TGF-β signalling by protein phosphatases

(2010) Ting Liu et al.   BIOCHEMICAL JOURNAL

Stimulation of angiotensin AT2 receptors by the non-peptide agonist, Compound 21, evokes vasodepressor effects in conscious spontaneously hypertensive rats

(2010) S Bosnyak et al.   BRITISH JOURNAL OF PHARMACOLOGY

SIRT3 Is a Mitochondria-Localized Tumor Suppressor Required for Maintenance of Mitochondrial Integrity and Metabolism during Stress

(2010) Hyun-Seok Kim et al.   CANCER CELL

Inhibition and Genetic Ablation of the B7/CD28 T-Cell Costimulation Axis Prevents Experimental Hypertension

(2010) Antony Vinh et al.   CIRCULATION

Angiotensin-Converting Enzyme 2 (ACE2) in Disease Pathogenesis

(2010) Yumiko Imai et al.   CIRCULATION JOURNAL

Angiotensin II Inhibits Neuronal Nitric Oxide Synthase Activation Through the ERK1/2-RSK Signaling Pathway to Modulate Central Control of Blood Pressure

(2010) Wen-Han Cheng et al.   CIRCULATION RESEARCH

Nicotinamide Adenine Dinucleotide Phosphate Reduced Oxidase 5 (Nox5) Regulation by Angiotensin II and Endothelin-1 Is Mediated via Calcium/Calmodulin-Dependent, Rac-1-Independent Pathways in Human Endothelial Cells

(2010) Augusto C. Montezano et al.   CIRCULATION RESEARCH

Central and Peripheral Mechanisms of T-Lymphocyte Activation and Vascular Inflammation Produced by Angiotensin II–Induced Hypertension

(2010) Paul J. Marvar et al.   CIRCULATION RESEARCH

The (Pro)renin Receptor/ATP6AP2 is Essential for Vacuolar H + -ATPase Assembly in Murine Cardiomyocytes

(2010) Kenichiro Kinouchi et al.   CIRCULATION RESEARCH

Novel Nox homologues in the vasculature: focusing on Nox4 and Nox5

(2010) Augusto C. Montezano et al.   CLINICAL SCIENCE

Oxidative Stress and Hypertension: Current Concepts

(2010) Ana M. Briones et al.   CURRENT HYPERTENSION REPORTS

Adipokines and blood pressure control

(2010) Frederique Yiannikouris et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Arterial aging: a journey into subclinical arterial disease

(2010) Mingyi Wang et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Role of the adaptive immune system in hypertension

(2010) David G Harrison et al.   CURRENT OPINION IN PHARMACOLOGY

Effects of PPARγ on hypertension, atherosclerosis, and chronic kidney disease

(2010) Akira Sugawara et al.   ENDOCRINE JOURNAL

miRNAs: roles and clinical applications in vascular disease

(2010) Md Saha Jamaluddin et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Vascular Smooth Muscle Cell Differentiation to an Osteogenic Phenotype Involves TRPM7 Modulation by Magnesium

(2010) Augusto C. Montezano et al.   HYPERTENSION

Prorenin, Renin, and Their Receptor

(2010) Timothy L. Reudelhuber   HYPERTENSION

Elevated Mineralocorticoid Receptor Activity in Aged Rat Vascular Smooth Muscle Cells Promotes a Proinflammatory Phenotype via Extracellular Signal-Regulated Kinase 1/2 Mitogen-Activated Protein Kinase and Epidermal Growth Factor Receptor-Dependent Pathways

(2010) Alexander W. Krug et al.   HYPERTENSION

Lifetime Overproduction of Circulating Angiotensin-(1-7) Attenuates Deoxycorticosterone Acetate-Salt Hypertension-Induced Cardiac Dysfunction and Remodeling

(2010) Nívia M. Santiago et al.   HYPERTENSION

MMP-2 Mediates Angiotensin II–Induced Hypertension Under the Transcriptional Control of MMP-7 and TACE

(2010) Jeffrey Odenbach et al.   HYPERTENSION

The Role of SnoN in Transforming Growth Factor β1-induced Expression of Metalloprotease-Disintegrin ADAM12

(2010) Emilia Solomon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Renal vasoconstrictor and pressor responses to angiotensin IV in mice are AT1a-receptor mediated

(2010) Rui Yang et al.   JOURNAL OF HYPERTENSION

Treatment with valsartan stimulates endothelial progenitor cells and renal label-retaining cells in hypertensive rats

(2010) Yoshinori Yoshida et al.   JOURNAL OF HYPERTENSION

Angiotensin (1–7) and its receptor Mas are expressed in the human testis: implications for male infertility

(2010) Augusto B. Reis et al.   JOURNAL OF MOLECULAR HISTOLOGY

Location of Prorenin Receptors in Primate Substantia Nigra: Effects on Dopaminergic Cell Death

(2010) Rita Valenzuela et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Atrap Deficiency Increases Arterial Blood Pressure and Plasma Volume

(2010) M. Oppermann et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Aortic Adventitial Fibroblasts Participate in Angiotensin-Induced Vascular Wall Inflammation and Remodeling

(2010) Brian C. Tieu et al.   JOURNAL OF VASCULAR RESEARCH

The Rho exchange factor Arhgef1 mediates the effects of angiotensin II on vascular tone and blood pressure

(2010) Christophe Guilluy et al.   NATURE MEDICINE

The role of Rho protein signaling in hypertension

(2010) Gervaise Loirand et al.   Nature Reviews Cardiology

Physiology of Kidney Renin

(2010) Hayo Castrop et al.   PHYSIOLOGICAL REVIEWS

The renin–angiotensin system in retinal health and disease: Its influence on neurons, glia and the vasculature

(2010) Erica L. Fletcher et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Requirement of Prorenin Receptor and Vacuolar H+-ATPase-Mediated Acidification for Wnt Signaling

(2010) C.-M. Cruciat et al.   SCIENCE

Signaling mechanisms of angiotensin II in regulating vascular senescence

(2009) Li-Juan Min et al.   AGEING RESEARCH REVIEWS

Genetic Polymorphism on Type 2 Receptor of Angiotensin II, Modifies Cardiovascular Risk And Systemic Inflammation in Hypertensive Males

(2009) D. Tousoulis et al.   AMERICAN JOURNAL OF HYPERTENSION

Blockage of the Renin-Angiotensin System Attenuates Mortality but Not Vascular Calcification in Uremic Rats: Sevelamer Carbonate Prevents Vascular Calcification

(2009) Masanori Tokumoto et al.   AMERICAN JOURNAL OF NEPHROLOGY

Angiotensin II induces RhoA activation through SHP2-dependent dephosphorylation of the RhoGAP p190A in vascular smooth muscle cells

(2009) Jeremy Bregeon et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Transforming growth factor-β signaling in hypertensive remodeling of porcine aorta

(2009) Natasa Popovic et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Angiotensin II, mechanotransduction, and pulsatile arterial hemodynamics in hypertension

(2009) Patrick Lacolley et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Differential regulation of angiotensin-(1-12) in plasma and cardiac tissue in response to bilateral nephrectomy

(2009) Carlos M. Ferrario et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Nox5 and the Regulation of Cellular Function

(2009) David J.R. Fulton   ANTIOXIDANTS & REDOX SIGNALING

Paradoxical effect of l-arginine: Acceleration of endothelial cell senescence

(2009) Fortunato Scalera et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The angiotensin II–AT1 receptor stimulates reactive oxygen species within the cell nucleus

(2009) Karl D. Pendergrass et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Poly(ADP-ribose) polymerase-1 (PARP-1) transcriptionally regulates angiotensin AT2 receptor (AT2R) and AT2R binding protein (ATBP) genes

(2009) Jana Reinemund et al.   BIOCHEMICAL PHARMACOLOGY

Endothelium-dependent contractions and endothelial dysfunction in human hypertension

(2009) Daniele Versari et al.   BRITISH JOURNAL OF PHARMACOLOGY

The role of the renin–angiotensin–aldosterone system in cardiovascular progenitor cell function

(2009) Cheng Qian et al.   CLINICAL SCIENCE

The intracellular renin-angiotensin system in the heart

(2009) Rajesh Kumar et al.   CURRENT HYPERTENSION REPORTS

New insights into the regulation of angiotensin receptors

(2009) Masaki Mogi et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Molecular pathways of aging and hypertension

(2009) Giovanni G Camici et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Associations of coronary artery calcification and carotid intima-media thickness with plasma concentrations of vascular calcification inhibitors in type 2 diabetic patients

(2009) Masami Ishiyama et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Neointimal-specific induction of apoptosis by losartan results in regression of vascular lesion in rat aorta

(2009) Jacinthe Lemay et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The brain RAS and Alzheimer's disease

(2009) John W. Wright et al.   EXPERIMENTAL NEUROLOGY

The evolving story of the RAAS in hypertension, diabetes and CV disease - moving from macrovascular to microvascular targets

(2009) Ulrike Muscha Steckelings et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Endothelial Cells Negatively Modulate Reactive Oxygen Species Generation in Vascular Smooth Muscle Cells

(2009) Shaoping Xu et al.   HYPERTENSION

The (Pro)Renin Receptor

(2009) Andrew Advani et al.   HYPERTENSION

Interleukin 17 Promotes Angiotensin II–Induced Hypertension and Vascular Dysfunction

(2009) Meena S. Madhur et al.   HYPERTENSION

New Physiological Concepts of the Renin-Angiotensin System From the Investigation of Precursors and Products of Angiotensin I Metabolism

(2009) Carlos M. Ferrario   HYPERTENSION

Endothelial and Vascular Muscle PPARγ in Arterial Pressure Regulation

(2009) Curt D. Sigmund   HYPERTENSION

Bone Morphogenetic Protein 7 (BMP7) Gene Polymorphisms Are Associated With Inverse Relationships Between Vascular Calcification and BMD: The Diabetes Heart Study

(2009) Barry I Freedman et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Disruption of the Ang II type 1 receptor promotes longevity in mice

(2009) Ariela Benigni et al.   JOURNAL OF CLINICAL INVESTIGATION

Renovascular hypertension by two-kidney one-clip enhances endothelial progenitor cell mobilization in a p47phox-dependent manner

(2009) Gustavo Salguero et al.   JOURNAL OF HYPERTENSION

Angiotensin II type 1 receptor-associated protein prevents vascular smooth muscle cell senescence via inactivation of calcineurin/nuclear factor of activated T cells pathway

(2009) Li-Juan Min et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The Biology of the (Pro)Renin Receptor

(2009) G. Nguyen et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Mineral complexes and vascular calcification

(2009) W. Charles O'Neill   KIDNEY INTERNATIONAL

Imbalance between matrix metalloproteinases and tissue inhibitor of metalloproteinases in hypertensive vascular remodeling

(2009) Michele M. Castro et al.   MATRIX BIOLOGY

Selective labeling of IRAP by the tritiated AT4 receptor ligand [3H]Angiotensin IV and its stable analog [3H]AL-11

(2009) Heidi Demaegdt et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The adipose renin–angiotensin system: Role in cardiovascular disease

(2009) Sean Thatcher et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Angiotensin-(1-7) activates a tyrosine phosphatase and inhibits glucose-induced signalling in proximal tubular cells

(2009) E. Gava et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Angiotensin-(1-7) antagonist, A-779, microinjection into the caudal ventrolateral medulla of renovascular hypertensive rats restores baroreflex bradycardia

(2009) Luiza Michelle Cangussu et al.   PEPTIDES

Angiotensin receptors as determinants of life span

(2009) Paola Cassis et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

The Plastic Nature of the Vascular Wall: A Continuum of Remodeling Events Contributing to Control of Arteriolar Diameter and Structure

(2009) Luis A. Martinez-Lemus et al.   PHYSIOLOGY

Renin-angiotensin system in the pathogenesis of liver fibrosis

(2009) Regina Maria Pereira et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Regulation of T-cell function by endogenously produced angiotensin II

(2008) Nyssa E. Hoch et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Does the renin-angiotensin system also regulate intra-ocular pressure?

(2008) Anu Vaajanen et al.   ANNALS OF MEDICINE

Aldosterone and Angiotensin II Synergistically Stimulate Migration in Vascular Smooth Muscle Cells Through c-Src-Regulated Redox-Sensitive RhoA Pathways

(2008) A.C. Montezano et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

BMP-2 promotes phosphate uptake, phenotypic modulation, and calcification of human vascular smooth muscle cells

(2008) Xianwu Li et al.   ATHEROSCLEROSIS

Calcification is associated with loss of functional calcium-sensing receptor in vascular smooth muscle cells

(2008) Masih-ul Alam et al.   CARDIOVASCULAR RESEARCH

Angiotensin II promotes NO production, inhibits apoptosis and enhances adhesion potential of bone marrow-derived endothelial progenitor cells

(2008) Tao Yin et al.   CELL RESEARCH

Pericardial Fat, Visceral Abdominal Fat, Cardiovascular Disease Risk Factors, and Vascular Calcification in a Community-Based Sample

(2008) Guido A. Rosito et al.   CIRCULATION

Ste20-Related Kinase SLK Phosphorylates Ser188 of RhoA to Induce Vasodilation in Response to Angiotensin II Type 2 Receptor Activation

(2008) Christophe Guilluy et al.   CIRCULATION RESEARCH

Redox-Sensitive Signaling by Angiotensin II Involves Oxidative Inactivation and Blunted Phosphorylation of Protein Tyrosine Phosphatase SHP-2 in Vascular Smooth Muscle Cells From SHR

(2008) Fatiha Tabet et al.   CIRCULATION RESEARCH

Local adipose tissue renin-angiotensin system

(2008) Lisa A. Cassis et al.   CURRENT HYPERTENSION REPORTS

Serum levels of MMP-9 and TIMP-1 in primary hypertension and effect of antihypertensive treatment

(2008) Ibrahim Koral Onal et al.   European Journal of Internal Medicine

Angiotensin-(1–7): Pharmacological properties and pharmacotherapeutic perspectives

(2008) Dilek Iusuf et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Recent advances in the angiotensin-converting enzyme 2-angiotensin(1-7)-Mas axis

(2008) Robson A. S. Santos et al.   EXPERIMENTAL PHYSIOLOGY

Angiotensin II Type 2 Receptor Deletion Enhances Vascular Senescence by Methyl Methanesulfonate Sensitive 2 Inhibition

(2008) Li-Juan Min et al.   HYPERTENSION

Nox4 Oxidase Overexpression Specifically Decreases Endogenous Nox4 mRNA and Inhibits Angiotensin II–Induced Adventitial Myofibroblast Migration

(2008) Mounir J. Haurani et al.   HYPERTENSION

Hepatocyte Growth Factor, but not Vascular Endothelial Growth Factor, Attenuates Angiotensin II–Induced Endothelial Progenitor Cell Senescence

(2008) Fumihiro Sanada et al.   HYPERTENSION

Rho-kinase Contributes to Sustained RhoA Activation through Phosphorylation of p190A RhoGAP

(2008) Kazutaka Mori et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The early life origins of vascular ageing and cardiovascular risk: the EVA syndrome.[Review]

(2008) Peter Nilsson   JOURNAL OF HYPERTENSION

DNA damage, vascular senescence and atherosclerosis

(2008) Maria Grazia Andreassi   JOURNAL OF MOLECULAR MEDICINE-JMM

Spotlight on Renin

(2008) AH Jan Danser et al.   JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM

Suppression of the p53-Dependent Replicative Senescence Response by Lysophosphatidic Acid Signaling

(2008) R. M. Kortlever et al.   MOLECULAR CANCER RESEARCH

Effects of an ARB on Endothelial Progenitor Cell Function and Cardiovascular Oxidation in Hypertension

(2007) Y. Yu et al.   AMERICAN JOURNAL OF HYPERTENSION

Over-expression of angiotensin II type 2 receptor (agtr2) reduces atherogenesis and modulates LOX-1, endothelial nitric oxide synthase and heme-oxygenase-1 expression

(2007) Changping Hu et al.   ATHEROSCLEROSIS

Over-expression of angiotensin II type 2 receptor (agtr2) decreases collagen accumulation in atherosclerotic plaque

(2007) Abhijit Dandapat et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS