In SilicoPrediction of Gamma-Aminobutyric Acid Type-A Receptors Using Novel Machine-Learning-Based SVM and GBDT Approaches

Direct Calculation of Protein Fitness Landscapes through Computational Protein Design

(2016) Loretta Au et al.   BIOPHYSICAL JOURNAL

Prediction of peptidoglycan hydrolases- a new class of antibacterial proteins

(2016) Ashok K. Sharma et al.   BMC GENOMICS

A Plasma-Based Protein Marker Panel for Colorectal Cancer Detection Identified by Multiplex Targeted Mass Spectrometry

(2016) Jeffrey J. Jones et al.   Clinical Colorectal Cancer

A novel machine learning method for cytokine-receptor interaction prediction

(2016) Leyi Wei et al.   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

Predicting bacteriophage proteins located in host cell with feature selection technique

(2016) Hui Ding et al.   COMPUTERS IN BIOLOGY AND MEDICINE

GABA A receptor π subunit promotes apoptosis of HTR-8/SVneo trophoblastic cells: Implications in preeclampsia

(2016) JUNJIE LU et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Identification of immunoglobulins using Chou's pseudo amino acid composition with feature selection technique

(2016) Hua Tang et al.   Molecular BioSystems

A novel features ranking metric with application to scalable visual and bioinformatics data classification

(2016) Quan Zou et al.   NEUROCOMPUTING

Multiplex protein pattern unmixing using a non-linear variable-weighted support vector machine as optimized by a particle swarm optimization algorithm

(2016) Qin Yang et al.   TALANTA

Recombination spot identification Based on gapped k-mers

(2016) Rong Wang et al.   Scientific Reports

iMiRNA-SSF: Improving the Identification of MicroRNA Precursors by Combining Negative Sets with Different Distributions

(2016) Junjie Chen et al.   Scientific Reports

Identification of drug–target interaction from interactome network with ‘guilt-by-association’ principle and topology features

(2015) Zhan-Chao Li et al.   BIOINFORMATICS

protr/ProtrWeb: R package and web server for generating various numerical representation schemes of protein sequences

(2015) Nan Xiao et al.   BIOINFORMATICS

Prediction of delayed graft function after kidney transplantation: comparison between logistic regression and machine learning methods

(2015) Alexander Decruyenaere et al.   BMC Medical Informatics and Decision Making

A novel mechanism for the anticonvulsant effect of furosemide in rat hippocampus in vitro

(2015) Josiane Uwera et al.   BRAIN RESEARCH

iORI-PseKNC: A predictor for identifying origin of replication with pseudo k-tuple nucleotide composition

(2015) Wen-Chao Li et al.   CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS

Molecular cloning, expression pattern, and molecular evolution of the spleen tyrosine kinase in lamprey, Lampetra japonica

(2015) Chang Liu et al.   DEVELOPMENT GENES AND EVOLUTION

Behavioral Effects of the Benzodiazepine-Positive Allosteric Modulator SH-053-2’F-S-CH3 in an Immune-Mediated Neurodevelopmental Disruption Model

(2015) Juliet Richetto et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Transmembrane AMPAR Regulatory Protein  -2 Is Required for the Modulation of GABA Release by Presynaptic AMPARs

(2015) M. Rigby et al.   JOURNAL OF NEUROSCIENCE

Improving tRNAscan-SE Annotation Results via Ensemble Classifiers

(2015) Quan Zou et al.   Molecular Informatics

GABAergic regulation of cerebellar NG2 cell development is altered in perinatal white matter injury

(2015) Marzieh Zonouzi et al.   NATURE NEUROSCIENCE

The human epilepsy mutation GABRG2(Q390X) causes chronic subunit accumulation and neurodegeneration

(2015) Jing-Qiong Kang et al.   NATURE NEUROSCIENCE

MAM-2201, a synthetic cannabinoid drug of abuse, suppresses the synaptic input to cerebellar Purkinje cells via activation of presynaptic CB1 receptors

(2015) Tomohiko Irie et al.   NEUROPHARMACOLOGY

Pse-in-One: a web server for generating various modes of pseudo components of DNA, RNA, and protein sequences

(2015) Bin Liu et al.   NUCLEIC ACIDS RESEARCH

The MEME Suite

(2015) Timothy L. Bailey et al.   NUCLEIC ACIDS RESEARCH

Transcriptome Analysis of the Central and Peripheral Nervous Systems of the Spider Cupiennius salei Reveals Multiple Putative Cys-Loop Ligand Gated Ion Channel Subunits and an Acetylcholine Binding Protein

(2015) Päivi H. Torkkeli et al.   PLoS One

Smart City Mobility Application—Gradient Boosting Trees for Mobility Prediction and Analysis Based on Crowdsourced Data

(2015) Ivana Semanjski et al.   SENSORS

Discrimination between Alzheimer’s Disease and Late Onset Bipolar Disorder Using Multivariate Analysis

(2015) Ariadna Besga et al.   Frontiers in Aging Neuroscience

iTIS-PseTNC: A sequence-based predictor for identifying translation initiation site in human genes using pseudo trinucleotide composition

(2014) Wei Chen et al.   ANALYTICAL BIOCHEMISTRY

Mass Spectrometry Quantifies Protein Interactions-From Molecular Chaperones to Membrane Porins

(2014) Jonathan T. S. Hopper et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

repDNA: a Python package to generate various modes of feature vectors for DNA sequences by incorporating user-defined physicochemical properties and sequence-order effects

(2014) Bin Liu et al.   BIOINFORMATICS

nDNA-prot: identification of DNA-binding proteins based on unbalanced classification

(2014) Li Song et al.   BMC BIOINFORMATICS

Enhancedin vitroCA1 network activity in a sodium channel β1(C121W) subunit model of genetic epilepsy

(2014) Robert J. Hatch et al.   EPILEPSIA

GABA(A) Receptor Pi (GABRP) Stimulates Basal-like Breast Cancer Cell Migration through Activation of Extracellular-regulated Kinase 1/2 (ERK1/2)

(2014) Gina M. Sizemore et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal structure of a human GABAA receptor

(2014) Paul S. Miller et al.   NATURE

Mass Spectrometric Detection and Characterization of Atypical Membrane-Bound Zinc-Sensitive Phosphatases Modulating GABAA Receptors

(2014) Mounia SidAhmed-Mezi et al.   PLoS One

In silico prediction of toxicity of non-congeneric industrial chemicals using ensemble learning based modeling approaches

(2014) Kunwar P. Singh et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Identification of cytokine via an improved genetic algorithm

(2014) Xiangxiang Zeng et al.   Frontiers of Computer Science

Disruption of pknG enhances production of gamma-aminobutyric acid by Corynebacterium glutamicum expressing glutamate decarboxylase

(2014) Naoko Okai et al.   AMB Express

Combining evolutionary information extracted from frequency profiles with sequence-based kernels for protein remote homology detection

(2013) Bin Liu et al.   BIOINFORMATICS

Prediction of Golgi-resident protein types by using feature selection technique

(2013) Hui Ding et al.   CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS

A Gradient Boosting Algorithm for Survival Analysis via Direct Optimization of Concordance Index

(2013) Yifei Chen et al.   Computational and Mathematical Methods in Medicine

BinMemPredict: a Web Server and Software for Predicting Membrane Protein Types

(2013) Quan Zou et al.   Current Proteomics

Learning Nonlinear Functions Using Regularized Greedy Forest

(2013) Rie Johnson et al.   IEEE TRANSACTIONS ON PATTERN ANALYSIS AND MACHINE INTELLIGENCE

Improved and Promising Identification of Human MicroRNAs by Incorporating a High-Quality Negative Set

(2013) Leyi Wei et al.   IEEE-ACM Transactions on Computational Biology and Bioinformatics

γ-Aminobutyric Acid(C) (GABAC) Selective Antagonists Derived from the Bioisosteric Modification of 4-Aminocyclopent-1-enecarboxylic Acid: Amides and Hydroxamates

(2013) Katherine E. S. Locock et al.   JOURNAL OF MEDICINAL CHEMISTRY

Proteome Analysis of Plastids from Developing Seeds of Jatropha curcas L.

(2013) Camila B. Pinheiro et al.   JOURNAL OF PROTEOME RESEARCH

LibD3C: Ensemble classifiers with a clustering and dynamic selection strategy

(2013) Chen Lin et al.   NEUROCOMPUTING

Hierarchical Classification of Protein Folds Using a Novel Ensemble Classifier

(2013) Chen Lin et al.   PLoS One

AcalPred: A Sequence-Based Tool for Discriminating between Acidic and Alkaline Enzymes

(2013) Hao Lin et al.   PLoS One

An Approach for Identifying Cytokines Based on a Novel Ensemble Classifier

(2013) Quan Zou et al.   Biomed Research International

Methylene Blue Inhibits the Function of α7-Nicotinic Acetylcholine Receptors

(2012) Abdulla S. Al Mansouri et al.   CNS & Neurological Disorders-Drug Targets

Prediction of the types of ion channel-targeted conotoxins based on radial basis function network

(2012) Lu-Feng Yuan et al.   TOXICOLOGY IN VITRO

Targeting the restricted α-subunit repertoire of airway smooth muscle GABAA receptors augments airway smooth muscle relaxation

(2011) George Gallos et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Mutagenesis Objective Search and Selection Tool (MOSST): an algorithm to predict structure-function related mutations in proteins

(2011) Alvaro Olivera-Nappa et al.   BMC BIOINFORMATICS

Potential role of GABAA receptor subunit; GABRA6, GABRB2 and GABRR2 gene polymorphisms in epilepsy susceptibility and pharmacotherapy in North Indian population

(2011) Ritu Kumari et al.   CLINICA CHIMICA ACTA

Current therapeutic procedures in Dravet syndrome

(2011) CATHERINE CHIRON   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Prediction of GABAA receptor proteins using the concept of Chou's pseudo-amino acid composition and support vector machine

(2011) Hassan Mohabatkar et al.   JOURNAL OF THEORETICAL BIOLOGY

Selective Pyramidal Cell Reduction of GABAA Receptor α1 Subunit Messenger RNA Expression in Schizophrenia

(2011) Jill R Glausier et al.   NEUROPSYCHOPHARMACOLOGY

GABRA2 and Alcohol Use Disorders: No Evidence of an Association in an Italian Case-Control Study

(2010) Nicoletta Onori et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

CD-HIT Suite: a web server for clustering and comparing biological sequences

(2010) Ying Huang et al.   BIOINFORMATICS

New therapeutic approaches for epilepsies, focusing on reorganization of the GABAA receptor subunits by neurosteroids

(2010) Yoshiya L. Murashima et al.   EPILEPSIA

Photochemical Proteolysis of an Unstructured Linker of the GABAAR Extracellular Domain Prevents GABA but Not Pentobarbital Activation

(2010) A. P. Hanek et al.   MOLECULAR PHARMACOLOGY

Binding, activation and modulation of Cys-loop receptors

(2010) Paul S. Miller et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Modulation of ion channels in clinical psychopharmacology: adults and younger people

(2010) Lindsey I Sinclair et al.   Expert Review of Clinical Pharmacology

Acute Increase of the Glutamate-Glutamine Cycling in Discrete Brain Areas after Administration of a Single Dose of Amphetamine

(2009) Frederico C. Pereira et al.   Annals of the New York Academy of Sciences

Antiepileptic drug resistant rats differ from drug responsive rats in GABAA receptor subunit expression in a model of temporal lobe epilepsy

(2008) Kerstin Bethmann et al.   NEUROBIOLOGY OF DISEASE

The anti-convulsant stiripentol acts directly on the GABAA receptor as a positive allosteric modulator

(2008) Janet L. Fisher   NEUROPHARMACOLOGY

International Union of Pharmacology. LXX. Subtypes of  -Aminobutyric AcidA Receptors: Classification on the Basis of Subunit Composition, Pharmacology, and Function. Update

(2008) R. W. Olsen et al.   PHARMACOLOGICAL REVIEWS

Mechanisms of human inherited epilepsies

(2008) Christopher A. Reid et al.   PROGRESS IN NEUROBIOLOGY

E/I balance and GABAA receptor plasticity

(2008) Jean-Marc Fritschy   Frontiers in Molecular Neuroscience

PseAAC: A flexible web server for generating various kinds of protein pseudo amino acid composition

(2007) Hong-Bin Shen et al.   ANALYTICAL BIOCHEMISTRY