Mass Spectrometry Quantifies Protein Interactions-From Molecular Chaperones to Membrane Porins

Determination of Protein–Ligand Binding Constants of a Cooperatively Regulated Tetrameric Enzyme Using Electrospray Mass Spectrometry

(2013) Dragana Cubrilovic et al.   ACS Chemical Biology

Quantifying Protein Interactions with Isomeric Carbohydrate Ligands Using a Catch and Release Electrospray Ionization-Mass Spectrometry Assay

(2013) Amr El-Hawiet et al.   ANALYTICAL CHEMISTRY

Quantifying Protein–Ligand Interactions by Direct Electrospray Ionization-MS Analysis: Evidence of Nonuniform Response Factors Induced by High Molecular Weight Molecules and Complexes

(2013) Hong Lin et al.   ANALYTICAL CHEMISTRY

Studying 18 MDa Virus Assemblies with Native Mass Spectrometry

(2013) Joost Snijder et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Assembly of Hemoglobin from Denatured Monomeric Subunits: Heme Ligation Effects and Off-Pathway Intermediates Studied by Electrospray Mass Spectrometry

(2013) Jiangjiang Liu et al.   BIOCHEMISTRY

Detergent Release Prolongs the Lifetime of Native-like Membrane Protein Conformations in the Gas-Phase

(2013) Antoni J. Borysik et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Measuring Positive Cooperativity Using the Direct ESI-MS Assay. Cholera Toxin B Subunit Homopentamer Binding to GM1 Pentasaccharide

(2013) Hong Lin et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Interpretation and Deconvolution of Nanodisc Native Mass Spectra

(2013) Michael T. Marty et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Identifying Carbohydrate Ligands of a Norovirus P Particle using a Catch and Release Electrospray Ionization Mass Spectrometry Assay

(2013) Ling Han et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Detergent-free mass spectrometry of membrane protein complexes

(2013) Jonathan T S Hopper et al.   NATURE METHODS

Mass spectrometry of intact membrane protein complexes

(2013) Arthur Laganowsky et al.   Nature Protocols

Conformational ensemble of the sodium-coupled aspartate transporter

(2013) Elka R Georgieva et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Conformational heterogeneity of the aspartate transporter GltPh

(2013) Inga Hänelt et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

C-terminal interactions mediate the quaternary dynamics of  B-crystallin

(2013) G. R. Hilton et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Mass spectrometry reveals synergistic effects of nucleotides, lipids, and drugs binding to a multidrug resistance efflux pump

(2013) J. Marcoux et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Allosteric mechanisms can be distinguished using structural mass spectrometry

(2013) A. Dyachenko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Twenty Years of Gas Phase Structural Biology

(2013) Julien Marcoux et al.   STRUCTURE

Mechanism and Rates of Exchange of L7/L12 between Ribosomes and the Effects of Binding EF-G

(2012) Stéphanie Deroo et al.   ACS Chemical Biology

Quantifying Ligand Binding to Large Protein Complexes Using Electrospray Ionization Mass Spectrometry

(2012) Amr El-Hawiet et al.   ANALYTICAL CHEMISTRY

Protein–Glycosphingolipid Interactions Revealed Using Catch-and-Release Mass Spectrometry

(2012) Yixuan Zhang et al.   ANALYTICAL CHEMISTRY

Massign: An Assignment Strategy for Maximizing Information from the Mass Spectra of Heterogeneous Protein Assemblies

(2012) Nina Morgner et al.   ANALYTICAL CHEMISTRY

Unraveling the Mechanism of Electrospray Ionization

(2012) Lars Konermann et al.   ANALYTICAL CHEMISTRY

Affinities of recombinant norovirus P dimers for human blood group antigens

(2012) Ling Han et al.   GLYCOBIOLOGY

Probing Affinity and Ubiquitin Linkage Selectivity of Ubiquitin-Binding Domains Using Mass Spectrometry

(2012) Kleitos Sokratous et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Quantifying Protein-Ligand Binding Constants using Electrospray Ionization Mass Spectrometry: A Systematic Binding Affinity Study of a Series of Hydrophobically Modified Trypsin Inhibitors

(2012) Dragana Cubrilovic et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Do Charge State Signatures Guarantee Protein Conformations?

(2012) Zoe Hall et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Reliable Determinations of Protein–Ligand Interactions by Direct ESI-MS Measurements. Are We There Yet?

(2012) Elena N. Kitova et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Evidence for the Preservation of Native Inter- and Intra-Molecular Hydrogen Bonds in the Desolvated FK-Binding Protein·FK506 Complex Produced by Electrospray Ionization

(2012) Jonathan T. S. Hopper et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

High-sensitivity Orbitrap mass analysis of intact macromolecular assemblies

(2012) Rebecca J Rose et al.   NATURE METHODS

Study on the noncovalent interactions of saikosaponins and cytochrome c by electrospray ionization mass spectrometry

(2012) Yingzhi Liu et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Charge state and adduct reduction in electrospray ionization–mass spectrometry using solvent vapor exposure

(2011) Jonathan T.S. Hopper et al.   ANALYTICAL BIOCHEMISTRY

Applications of a Catch and Release Electrospray Ionization Mass Spectrometry Assay for Carbohydrate Library Screening

(2011) Amr El-Hawiet et al.   ANALYTICAL CHEMISTRY

Alkali Metal Cation-Induced Destabilization of Gas-Phase Protein–Ligand Complexes: Consequences and Prevention

(2011) Jonathan T. S. Hopper et al.   ANALYTICAL CHEMISTRY

Native Electrospray and Electron-Capture Dissociation FTICR Mass Spectrometry for Top-Down Studies of Protein Assemblies

(2011) Hao Zhang et al.   ANALYTICAL CHEMISTRY

Development of Submillisecond Time-Resolved Mass Spectrometry Using Desorption Electrospray Ionization

(2011) Zhixin Miao et al.   ANALYTICAL CHEMISTRY

Modern Biomolecular Mass Spectrometry and its Role in Studying Virus Structure, Dynamics, and Assembly

(2011) Charlotte Uetrecht et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Advances in the Mass Spectrometry of Membrane Proteins: From Individual Proteins to Intact Complexes

(2011) Nelson P. Barrera et al.   Annual Review of Biochemistry

Mass spectrometry: come of age for structural and dynamical biology

(2011) Justin LP Benesch et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Dynamic Ligand-induced Conformational Rearrangements in P-glycoprotein as Probed by Fluorescence Resonance Energy Transfer Spectroscopy

(2011) Brandy Verhalen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

αB-Crystallin Polydispersity Is a Consequence of Unbiased Quaternary Dynamics

(2011) Andrew J. Baldwin et al.   JOURNAL OF MOLECULAR BIOLOGY

What Happens to Hydrophobic Interactions during Transfer from the Solution to the Gas Phase? The Case of Electrospray-Based Soft Ionization Methods

(2011) Konstantin Barylyuk et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Quantifying Protein-Fatty Acid Interactions Using Electrospray Ionization Mass Spectrometry

(2011) Lan Liu et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Central dogma at the single-molecule level in living cells

(2011) Gene-Wei Li et al.   NATURE

Heterogeneity and dynamics in the assembly of the Heat Shock Protein 90 chaperone complexes

(2011) I.-o. Ebong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enhancements in travelling wave ion mobility resolution

(2011) Kevin Giles et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Quantitative Analysis of the Interaction Strength and Dynamics of Human IgG4 Half Molecules by Native Mass Spectrometry

(2011) Rebecca J. Rose et al.   STRUCTURE

Drug–protein binding: a critical review of analytical tools

(2010) Karine Vuignier et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

A Method for Removing Effects of Nonspecific Binding on the Distribution of Binding Stoichiometries: Application to Mass Spectroscopy Data

(2010) Liat Shimon et al.   BIOPHYSICAL JOURNAL

Separating and visualising protein assemblies by means of preparative mass spectrometry and microscopy

(2010) Justin L.P. Benesch et al.   JOURNAL OF STRUCTURAL BIOLOGY

Evidence that Water Can Reduce the Kinetic Stability of Protein−Hydrophobic Ligand Interactions

(2010) Lan Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ion Mobility Mass Spectrometry of Two Tetrameric Membrane Protein Complexes Reveals Compact Structures and Differences in Stability and Packing

(2010) Sheila C. Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Subunit exchange rates in Hepatitis B virus capsids are geometry- and temperature-dependent

(2010) Charlotte Uetrecht et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Elongated oligomers in  2-microglobulin amyloid assembly revealed by ion mobility spectrometry-mass spectrometry

(2010) D. P. Smith et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Electrospray ionization mass spectrometry of zinc, cadmium, and copper metallothioneins: Evidence for metal-binding cooperativity

(2010) Peter M. Gehrig et al.   PROTEIN SCIENCE

High-Resolution Ion Cyclotron Mobility Spectrometry

(2009) Samuel I. Merenbloom et al.   ANALYTICAL CHEMISTRY

Ion mobility mass spectrometry of proteins and proteinassemblies

(2009) Charlotte Uetrecht et al.   CHEMICAL SOCIETY REVIEWS

A Monte Carlo approach for assessing the specificity of protein oligomers observed in nano-electrospray mass spectra

(2009) Laura A. Lane et al.   INTERNATIONAL JOURNAL OF MASS SPECTROMETRY

Hydrophobic Protein−Ligand Interactions Preserved in the Gas Phase

(2009) Lan Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dehydrated but unharmed

(2009) Justin L. P. Benesch et al.   NATURE

Avid interactions underlie the Lys63-linked polyubiquitin binding specificities observed for UBA domains

(2009) Joshua J Sims et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding

(2009) S. G. Aller et al.   SCIENCE

Crystallin proteins and amyloid fibrils

(2008) H. Ecroyd et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Real-Time Monitoring of Protein Complexes Reveals their Quaternary Organization and Dynamics

(2008) Alexander J. Painter et al.   CHEMISTRY & BIOLOGY

Controlled Assembly of Bifunctional Chimeric Protein Cages and Composition Analysis Using Noncovalent Mass Spectrometry

(2008) Sebyung Kang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stepwise evolution of protein native structure with electrospray into the gas phase, 10-12 to 102 s

(2008) K. Breuker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tandem mass spectrometry experiments support the existence of hydrophobic interactions in the gas phase

(2008) Rafał Frański et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Mass spectrometric investigations ofα- andβ-cyclodextrin complexes withortho-,meta- andpara-coumaric acids by negative mode electrospray ionization

(2008) Bogdan Kralj et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Micelles Protect Membrane Complexes from Solution to Vacuum

(2008) N. P. Barrera et al.   SCIENCE