Viperid Envenomation Wound Exudate Contributes to Increased Vascular Permeability via a DAMPs/TLR-4 Mediated Pathway

Disorders of Vascular Permeability

(2016) Cindy Park-Windhol et al.   Annual Review of Pathology-Mechanisms of Disease

Inflammatory and fibrotic responses of cardiac fibroblasts to myocardial damage associated molecular patterns (DAMPs)

(2016) Neil A. Turner   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The role of TLR2 in the acute inflammatory response induced by Bothrops atrox snake venom

(2016) Vanessa Moreira et al.   TOXICON

Muscle Tissue Damage Induced by the Venom of Bothrops asper: Identification of Early and Late Pathological Events through Proteomic Analysis

(2016) Cristina Herrera et al.   PLoS Neglected Tropical Diseases

Vascular endothelial cell Toll-like receptor pathways in sepsis

(2015) Samira Khakpour et al.   Innate Immunity

Pivotal role for decorin in angiogenesis

(2015) Hannu Järveläinen et al.   MATRIX BIOLOGY

Eritoran inhibits S100A8-mediated TLR4/MD-2 activation and tumor growth by changing the immune microenvironment

(2015) A Deguchi et al.   ONCOGENE

DAMPs from Cell Death to New Life

(2015) Emilie Vénéreau et al.   Frontiers in Immunology

Complexity of Danger: The Diverse Nature of Damage-associated Molecular Patterns

(2014) Liliana Schaefer   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional Characterization of S100A8 and S100A9 in Altering Monolayer Permeability of Human Umbilical Endothelial Cells

(2014) Liqun Wang et al.   PLoS One

Critical Role of TLR2 and MyD88 for Functional Response of Macrophages to a Group IIA-Secreted Phospholipase A2 from Snake Venom

(2014) Elbio Leiguez et al.   PLoS One

DAMP Molecule S100A9 Acts as a Molecular Pattern to Enhance Inflammation during Influenza A Virus Infection: Role of DDX21-TRIF-TLR4-MyD88 Pathway

(2014) Su-Yu Tsai et al.   PLoS Pathogens

Alarmin-induced cell migration

(2013) De Yang et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The crucial role of the MyD88 adaptor protein in the inflammatory response induced by Bothrops atrox venom

(2013) Vanessa Moreira et al.   TOXICON

TLR4 activation of TRPC6-dependent calcium signaling mediates endotoxin-induced lung vascular permeability and inflammation

(2012) Mohammad Tauseef et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Histones from Dying Renal Cells Aggravate Kidney Injury via TLR2 and TLR4

(2012) R. Allam et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Homogenates of skeletal muscle injected with snake venom inhibit myogenic differentiation in cell culture

(2012) Patricia Saravia-Otten et al.   MUSCLE & NERVE

TLR4 signaling protects from excessive muscular damage induced by Bothrops jararacussu snake venom

(2012) Eustaquio Luiz Paiva-Oliveira et al.   TOXICON

Signaling in Innate Immunity and Inflammation

(2012) K. Newton et al.   Cold Spring Harbor Perspectives in Biology

Envenomations by Bothrops and Crotalus Snakes Induce the Release of Mitochondrial Alarmins

(2012) Irene Zornetta et al.   PLoS Neglected Tropical Diseases

A Lys49 PhospholipaseA2, Isolated fromBothrops asperSnake Venom, Induces Lipid Droplet Formation in Macrophages Which Depends on Distinct Signaling Pathways and the C-Terminal Region

(2012) Karina Cristina Giannotti et al.   Biomed Research International

Wound Macrophages as Key Regulators of Repair

(2011) Samielle K. Brancato et al.   AMERICAN JOURNAL OF PATHOLOGY

Macrophages in skin injury and repair

(2011) Babak Mahdavian Delavary et al.   IMMUNOBIOLOGY

Efficacy of IgG and F(ab′)2 Antivenoms to Neutralize Snake Venom-induced Local Tissue Damage as Assessed by the Proteomic Analysis of Wound Exudate

(2011) Alexandra Rucavado et al.   JOURNAL OF PROTEOME RESEARCH

Proteomics of Wound Exudate in Snake Venom-Induced Pathology: Search for Biomarkers To Assess Tissue Damage and Therapeutic Success

(2011) Alexandra Rucavado et al.   JOURNAL OF PROTEOME RESEARCH

Role of Collagens and Perlecan in Microvascular Stability: Exploring the Mechanism of Capillary Vessel Damage by Snake Venom Metalloproteinases

(2011) Teresa Escalante et al.   PLoS One

Fibrinogen as a key regulator of inflammation in disease

(2011) Dimitrios Davalos et al.   Seminars in Immunopathology

Snake bite

(2010) David A Warrell   LANCET

DAMPening Inflammation by Modulating TLR Signalling

(2010) A. M. Piccinini et al.   MEDIATORS OF INFLAMMATION

Bothrops snake myotoxins induce a large efflux of ATP and potassium with spreading of cell damage and pain

(2010) M. Cintra-Francischinelli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular mechanisms of endothelial hyperpermeability: implications in inflammation

(2009) Puneet Kumar et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Wound Exudate as a Proteomic Window to Reveal Different Mechanisms of Tissue Damage by Snake Venom Toxins

(2009) Teresa Escalante et al.   JOURNAL OF PROTEOME RESEARCH

Inflammation induced by Bothrops asper venom

(2009) Catarina Teixeira et al.   TOXICON

Experimental pathology of local tissue damage induced by Bothrops asper snake venom

(2009) José María Gutiérrez et al.   TOXICON

Tissue pathology induced by snake venoms: How to understand a complex pattern of alterations from a systems biology perspective?

(2009) José María Gutiérrez et al.   TOXICON

Hyaluronan fragments induce cytokine and metalloprotease upregulation in human melanoma cells in part by signalling via TLR4

(2007) Verena Voelcker et al.   EXPERIMENTAL DERMATOLOGY