Alarmin-induced cell migration

Maturing Dendritic Cells Depend on RAGE for In Vivo Homing to Lymph Nodes

(2014) A. A. Manfredi et al.   JOURNAL OF IMMUNOLOGY

Lactoferrin Acts as an Alarmin to Promote the Recruitment and Activation of APCs and Antigen-Specific Immune Responses

(2014) G. de la Rosa et al.   JOURNAL OF IMMUNOLOGY

Chemotactic Activity of S100A7 (Psoriasin) Is Mediated by the Receptor for Advanced Glycation End Products and Potentiates Inflammation with Highly Homologous but Functionally Distinct S100A15

(2014) R. Wolf et al.   JOURNAL OF IMMUNOLOGY

Heat Shock Protein 70, Released from Heat-Stressed Tumor Cells, Initiates Antitumor Immunity by Inducing Tumor Cell Chemokine Production and Activating Dendritic Cells via TLR4 Pathway

(2014) T. Chen et al.   JOURNAL OF IMMUNOLOGY

HMGB-1 induces cell motility and α5β1 integrin expression in human chondrosarcoma cells

(2012) Chih-Hsin Tang et al.   CANCER LETTERS

HMGB1 promotes recruitment of inflammatory cells to damaged tissues by forming a complex with CXCL12 and signaling via CXCR4

(2012) Milena Schiraldi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The IKK -Dependent NF- B p52/RelB Noncanonical Pathway Is Essential To Sustain a CXCL12 Autocrine Loop in Cells Migrating in Response to HMGB1

(2012) R. R. Kew et al.   JOURNAL OF IMMUNOLOGY

New insights regarding the regulation of chemotaxis by nucleotides, adenosine, and their receptors

(2012) Ross Corriden et al.   Purinergic Signalling

A Decade of Imaging Cellular Motility and Interaction Dynamics in the Immune System

(2012) R. N. Germain et al.   SCIENCE

Paneth Cells Regulate Both Chemotaxis of Immature Dendritic Cells and Cytokine Production from Epithelial Cells

(2012) Takahiro Ito et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

HMGB1 Is a Therapeutic Target for Sterile Inflammation and Infection

(2011) Ulf Andersson et al.   Annual Review of Immunology

Human mesenchymal stem cells respond to native but not oxidized damage associated molecular pattern molecules from necrotic (tumor) material

(2011) Ramin Lotfi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

An Unexpected Role for Uric Acid as an Inducer of T Helper 2 Cell Immunity to Inhaled Antigens and Inflammatory Mediator of Allergic Asthma

(2011) Mirjam Kool et al.   IMMUNITY

Mas-related Gene X2 (MrgX2) Is a Novel G Protein-coupled Receptor for the Antimicrobial Peptide LL-37 in Human Mast Cells

(2011) Hariharan Subramanian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High-mobility group nucleosome-binding protein 1 acts as an alarmin and is critical for lipopolysaccharide-induced immune responses

(2011) De Yang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Effect of HMGB1, a Damage-Associated Molecular Pattern Molecule, on Polymorphonuclear Neutrophil Migration Depends on Its Concentration

(2011) Florence Berthelot et al.   Journal of Innate Immunity

High mobility group box-1 induces migration of vascular smooth muscle cells via TLR4-dependent PI3K/Akt pathway activation

(2011) Jian Yang et al.   MOLECULAR BIOLOGY REPORTS

Molecular and functional characterization of the gilthead seabream β-defensin demonstrate its chemotactic and antimicrobial activity

(2011) Alberto Cuesta et al.   MOLECULAR IMMUNOLOGY

Identification of the cathelicidin peptide LL-37 as agonist for the type I insulin-like growth factor receptor

(2011) A Girnita et al.   ONCOGENE

The synthetic peptides bovine enteric β-defensin (EBD), bovine neutrophil β-defensin (BNBD) 9 and BNBD 3 are chemotactic for immature bovine dendritic cells

(2011) Sarah Mackenzie-Dyck et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

IL-33 induces neutrophil migration in rheumatoid arthritis and is a target of anti-TNF therapy

(2010) W. A. Verri et al.   ANNALS OF THE RHEUMATIC DISEASES

Granulysin activates antigen-presenting cells through TLR4 and acts as an immune alarmin

(2010) P. Tewary et al.   BLOOD

Specific Binding and Chemotactic Activity of mBD4 and Its Functional Orthologue hBD2 to CCR6-expressing Cells

(2010) Johann Röhrl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Plasmacytoid dendritic cells sense skin injury and promote wound healing through type I interferons

(2010) Josh Gregorio et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cutting Edge: A Critical Role for the G Protein-Coupled Receptor mFPR2 in Airway Inflammation and Immune Responses

(2010) K. Chen et al.   JOURNAL OF IMMUNOLOGY

CCL20 and  -Defensin-2 Induce Arrest of Human Th17 Cells on Inflamed Endothelium In Vitro under Flow Conditions

(2010) S. Ghannam et al.   JOURNAL OF IMMUNOLOGY

Human  -Defensin 2 and 3 and Their Mouse Orthologs Induce Chemotaxis through Interaction with CCR2

(2010) J. Rohrl et al.   JOURNAL OF IMMUNOLOGY

Human Eosinophils Recognize Endogenous Danger Signal Crystalline Uric Acid and Produce Proinflammatory Cytokines Mediated by Autocrine ATP

(2010) T. Kobayashi et al.   JOURNAL OF IMMUNOLOGY

Interleukin-33 attenuates sepsis by enhancing neutrophil influx to the site of infection

(2010) Jose C Alves-Filho et al.   NATURE MEDICINE

The Toll-like receptor 4 ligands Mrp8 and Mrp14 are crucial in the development of autoreactive CD8+ T cells

(2010) Karin Loser et al.   NATURE MEDICINE

An Antimicrobial Peptide Regulates Tumor-Associated Macrophage Trafficking via the Chemokine Receptor CCR2, a Model for Tumorigenesis

(2010) Ge Jin et al.   PLoS One

CCR6 Regulation of the Actin Cytoskeleton Orchestrates Human Beta Defensin-2- and CCL20-mediated Restitution of Colonic Epithelial Cells

(2009) Rebecca A. Vongsa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Requirement of HMGB1 for stromal cell-derived factor-1/CXCL12-dependent migration of macrophages and dendritic cells

(2009) Lara Campana et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Isoleucine/leucine2 is essential for chemoattractant activity of β-defensin Defb14 through chemokine receptor 6

(2009) Christine Tyrrell et al.   MOLECULAR IMMUNOLOGY

The pro-inflammatory peptide LL-37 promotes ovarian tumor progression through recruitment of multipotent mesenchymal stromal cells

(2009) S. B. Coffelt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CD24 and Siglec-10 Selectively Repress Tissue Damage-Induced Immune Responses

(2009) G.-Y. Chen et al.   SCIENCE

Alarmins link neutrophils and dendritic cells

(2009) De Yang et al.   TRENDS IN IMMUNOLOGY

Mast Cell and Monocyte Recruitment by S100A12 and Its Hinge Domain

(2008) Wei Xing Yan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interaction of the RAGE Cytoplasmic Domain with Diaphanous-1 Is Required for Ligand-stimulated Cellular Migration through Activation of Rac1 and Cdc42

(2008) Barry I. Hudson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Eosinophil-derived neurotoxin acts as an alarmin to activate the TLR2–MyD88 signal pathway in dendritic cells and enhances Th2 immune responses

(2008) De Yang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

High-Mobility Group Box 1 Protein in Human and Murine Skin: Involvement in Wound Healing

(2008) Stefania Straino et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

High Mobility Group Box 1 Protein Inhibits the Proliferation of Human Mesenchymal Stem Cells and Promotes Their Migration and Differentiation along Osteoblastic Pathway

(2008) Erhong Meng et al.   STEM CELLS AND DEVELOPMENT