DAMP Molecule S100A9 Acts as a Molecular Pattern to Enhance Inflammation during Influenza A Virus Infection: Role of DDX21-TRIF-TLR4-MyD88 Pathway

Blockade of Antimicrobial Proteins S100A8 and S100A9 Inhibits Phagocyte Migration to the Alveoli in Streptococcal Pneumonia

(2014) M.-A. Raquil et al.   JOURNAL OF IMMUNOLOGY

Effect of Insulin-Like Growth Factor Blockade on Hyperoxia-Induced Lung Injury

(2012) Tae-Hyung Kim et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Immune Response to Seasonal Influenza A Virus Infection: A Proteomic Approach

(2012) Luis M. Teran et al.   ARCHIVES OF MEDICAL RESEARCH

Enteric-delivered rapamycin enhances resistance of aged mice to pneumococcal pneumonia through reduced cellular senescence

(2012) Cecilia A. Hinojosa et al.   EXPERIMENTAL GERONTOLOGY

Toll-like Receptor 4 Is Expressed on Intestinal Stem Cells and Regulates Their Proliferation and Apoptosis via the p53 Up-regulated Modulator of Apoptosis

(2012) Matthew D. Neal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transactivation of Inducible Nitric Oxide Synthase Gene by Kruppel-like Factor 6 Regulates Apoptosis during Influenza A Virus Infection

(2012) V. Mgbemena et al.   JOURNAL OF IMMUNOLOGY

Estimated global mortality associated with the first 12 months of 2009 pandemic influenza A H1N1 virus circulation: a modelling study

(2012) Fatimah S Dawood et al.   LANCET INFECTIOUS DISEASES

Constitutive Neutrophil Apoptosis: Regulation by Cell Concentration via S100 A8/9 and the MEK – ERK Pathway

(2012) Mizhir Atallah et al.   PLoS One

TLR2/MyD88/NF-κB Pathway, Reactive Oxygen Species, Potassium Efflux Activates NLRP3/ASC Inflammasome during Respiratory Syncytial Virus Infection

(2012) Jesus Segovia et al.   PLoS One

Influenza Virus A Infection of Human Monocyte and Macrophage Subpopulations Reveals Increased Susceptibility Associated with Cell Differentiation

(2012) Marieke A. Hoeve et al.   PLoS One

Novel Role for the Innate Immune Receptor Toll-Like Receptor 4 (TLR4) in the Regulation of the Wnt Signaling Pathway and Photoreceptor Apoptosis

(2012) Hyun Yi et al.   PLoS One

An Inflammation Loop Orchestrated by S100A9 and Calprotectin Is Critical for Development of Arthritis

(2012) Annabelle Cesaro et al.   PLoS One

Myeloid-Related Protein-14 Contributes to Protective Immunity in Gram-Negative Pneumonia Derived Sepsis

(2012) Ahmed Achouiti et al.   PLoS Pathogens

S100 Calcium Binding Proteins and Ion Channels

(2012) Anton Hermann et al.   Frontiers in Pharmacology

GM-CSF in the Lung Protects against Lethal Influenza Infection

(2011) Fang-Fang Huang et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Oncolytic targeting of androgen-sensitive prostate tumor by the respiratory syncytial virus (RSV): consequences of deficient interferon-dependent antiviral defense

(2011) Ibtissam Echchgadda et al.   BMC CANCER

DDX1, DDX21, and DHX36 Helicases Form a Complex with the Adaptor Molecule TRIF to Sense dsRNA in Dendritic Cells

(2011) Zhiqiang Zhang et al.   IMMUNITY

Virulence determinants of pandemic influenza viruses

(2011) Donna M. Tscherne et al.   JOURNAL OF CLINICAL INVESTIGATION

Damage-Associated Molecular Pattern S100A9 Increases Bactericidal Activity of Human Neutrophils by Enhancing Phagocytosis

(2011) J.-C. Simard et al.   JOURNAL OF IMMUNOLOGY

Viral pneumonia

(2011) Olli Ruuskanen et al.   LANCET

Evasion of innate and adaptive immune responses by influenza A virus

(2010) Mirco Schmolke et al.   CELLULAR MICROBIOLOGY

Localisation and trafficking of Toll-like receptors: an important mode of regulation

(2010) Anne F McGettrick et al.   CURRENT OPINION IN IMMUNOLOGY

Recognition of viruses by cytoplasmic sensors

(2010) Courtney Wilkins et al.   CURRENT OPINION IN IMMUNOLOGY

Viral tricks to grid-lock the type I interferon system

(2010) Gijs A Versteeg et al.   CURRENT OPINION IN MICROBIOLOGY

Respective roles of TLR, RIG-I and NLRP3 in influenza virus infection and immunity: impact on vaccine design

(2010) Takeshi Ichinohe   Expert Review of Vaccines

The PI3K/Akt pathway inhibits influenza A virus-induced Bax-mediated apoptosis by negatively regulating the JNK pathway via ASK1

(2010) X. Lu et al.   JOURNAL OF GENERAL VIROLOGY

Induction of neutrophil degranulation by S100A9 via a MAPK-dependent mechanism

(2010) Jean-Christophe Simard et al.   JOURNAL OF LEUKOCYTE BIOLOGY

MyD88 Signaling Is Indispensable for Primary Influenza A Virus Infection but Dispensable for Secondary Infection

(2010) S.-U. Seo et al.   JOURNAL OF VIROLOGY

DAMPening Inflammation by Modulating TLR Signalling

(2010) A. M. Piccinini et al.   MEDIATORS OF INFLAMMATION

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Highly pathogenic avian influenza A virus H5N1 NS1 protein induces caspase-dependent apoptosis in human alveolar basal epithelial cells

(2010) Chuanfu Zhang et al.   Virology Journal

A novel p53 target gene,S100A9, induces p53-dependent cellular apoptosis and mediates the p53 apoptosis pathway

(2009) Chunsun Li et al.   BIOCHEMICAL JOURNAL

Anticancer oncolytic activity of respiratory syncytial virus

(2009) I Echchgadda et al.   CANCER GENE THERAPY

S100A8/A9 induces autophagy and apoptosis via ROS-mediated cross-talk between mitochondria and lysosomes that involves BNIP3

(2009) Saeid Ghavami et al.   CELL RESEARCH

Role of TLR2- and TLR4-mediated signaling in Mycobacterium tuberculosis-induced macrophage death

(2009) Dulfary Sánchez et al.   CELLULAR IMMUNOLOGY

The NLRP3 Inflammasome Mediates In Vivo Innate Immunity to Influenza A Virus through Recognition of Viral RNA

(2009) Irving C. Allen et al.   IMMUNITY

Inflammasome recognition of influenza virus is essential for adaptive immune responses

(2009) Takeshi Ichinohe et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-10-Dependent S100A8 Gene Induction in Monocytes/Macrophages by Double-Stranded RNA

(2009) Y. Endoh et al.   JOURNAL OF IMMUNOLOGY

Influenza in immunosuppressed populations: a review of infection frequency, morbidity, mortality, and vaccine responses

(2009) Ken M Kunisaki et al.   LANCET INFECTIOUS DISEASES

Novel signaling interactions between proteinase-activated receptor 2 and Toll-like receptors in vitro and in vivo

(2009) Q M Nhu et al.   Mucosal Immunology

Activation of innate immune antiviral responses by Nod2

(2009) Ahmed Sabbah et al.   NATURE IMMUNOLOGY

Toll-like receptor-mediated activation of neutrophils by influenza A virus

(2008) J. P. Wang et al.   BLOOD

Identification of Oxidative Stress and Toll-like Receptor 4 Signaling as a Key Pathway of Acute Lung Injury

(2008) Yumiko Imai et al.   CELL

Role of Human β-Defensin-2 during Tumor Necrosis Factor-α/NF-κB-mediated Innate Antiviral Response against Human Respiratory Syncytial Virus

(2008) Srikanth Kota et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lung epithelial apoptosis in influenza virus pneumonia: the role of macrophage-expressed TNF-related apoptosis-inducing ligand

(2008) Susanne Herold et al.   JOURNAL OF EXPERIMENTAL MEDICINE