VapCs of Mycobacterium tuberculosis cleave RNAs essential for translation

Structural and functional studies of theMycobacterium tuberculosisVapBC30 toxin-antitoxin system: implications for the design of novel antimicrobial peptides

(2015) In-Gyun Lee et al.   NUCLEIC ACIDS RESEARCH

Growth-regulating Mycobacterium tuberculosis VapC-mt4 toxin is an isoacceptor-specific tRNase

(2015) Jonathan W. Cruz et al.   Nature Communications

MazF ribonucleases promote Mycobacterium tuberculosis drug tolerance and virulence in guinea pigs

(2015) Prabhakar Tiwari et al.   Nature Communications

Distinct type I and type II toxin-antitoxin modules control Salmonella lifestyle inside eukaryotic cells

(2015) Damián Lobato-Márquez et al.   Scientific Reports

Transfer RNAs Mediate the Rapid Adaptation of Escherichia coli to Oxidative Stress

(2015) Jiayong Zhong et al.   PLoS Genetics

Physiologic Stresses Reveal a Salmonella Persister State and TA Family Toxins Modulate Tolerance to These Stresses

(2015) Eugenia Silva-Herzog et al.   PLoS One

Molecular Mechanisms Underlying Bacterial Persisters

(2014) Etienne Maisonneuve et al.   CELL

Crystal structure of the VapBC-15 complex from Mycobacterium tuberculosis reveals a two-metal ion dependent PIN-domain ribonuclease and a variable mode of toxin–antitoxin assembly

(2014) Uddipan Das et al.   JOURNAL OF STRUCTURAL BIOLOGY

Latent Tuberculosis Infection: Myths, Models, and Molecular Mechanisms

(2014) N. K. Dutta et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Identification of Bacteriophage-Encoded Anti-sRNAs in Pathogenic Escherichia coli

(2014) Jai J. Tree et al.   MOLECULAR CELL

VapC from the Leptospiral VapBC Toxin-Antitoxin Module Displays Ribonuclease Activity on the Initiator tRNA

(2014) Alexandre P. Y. Lopes et al.   PLoS One

Internalization of Salmonella by Macrophages Induces Formation of Nonreplicating Persisters

(2014) S. Helaine et al.   SCIENCE

PAR-CLIP data indicate that Nrd1-Nab3-dependent transcription termination regulates expression of hundreds of protein coding genes in yeast

(2014) Shaun Webb et al.   GENOME BIOLOGY

RETRACTED: (p)ppGpp Controls Bacterial Persistence by Stochastic Induction of Toxin-Antitoxin Activity

(2013) Etienne Maisonneuve et al.   CELL

Advances in the development of new tuberculosis drugs and treatment regimens

(2013) Alimuddin Zumla et al.   NATURE REVIEWS DRUG DISCOVERY

Tuberculosis

(2013) Alimuddin Zumla et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identification and classification of bacterial Type III toxin–antitoxin systems encoded in chromosomal and plasmid genomes

(2012) Tim R. Blower et al.   NUCLEIC ACIDS RESEARCH

Determination of ribonuclease sequence-specificity using Pentaprobes and mass spectrometry

(2012) J. L. McKenzie et al.   RNA

A processed noncoding RNA regulates an altruistic bacterial antiviral system

(2011) Tim R Blower et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

VapC Toxins from Mycobacterium tuberculosis Are Ribonucleases that Differentially Inhibit Growth and Are Neutralized by Cognate VapB Antitoxins

(2011) Bintou Ahmadou Ahidjo et al.   PLoS One

Enteric virulence associated protein VapC inhibits translation by cleavage of initiator tRNA

(2011) K. S. Winther et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacterial persistence by RNA endonucleases

(2011) Etienne Maisonneuve et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Many Pathways of RNA Degradation

(2009) Jonathan Houseley et al.   CELL

Identification of protein binding sites on U3 snoRNA and pre-rRNA by UV cross-linking and high-throughput analysis of cDNAs

(2009) S. Granneman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Crystal Structure of the Ribosome Bound to EF-Tu and Aminoacyl-tRNA

(2009) T. M. Schmeing et al.   SCIENCE

Comprehensive Functional Analysis of Mycobacterium tuberculosis Toxin-Antitoxin Systems: Implications for Pathogenesis, Stress Responses, and Evolution

(2009) Holly R. Ramage et al.   PLoS Genetics

Three Mycobacterium tuberculosis Rel Toxin-Antitoxin Modules Inhibit Mycobacterial Growth and Are Expressed in Infected Human Macrophages

(2008) S. B. Korch et al.   JOURNAL OF BACTERIOLOGY

HicA of Escherichia coli Defines a Novel Family of Translation-Independent mRNA Interferases in Bacteria and Archaea

(2008) M. G. Jorgensen et al.   JOURNAL OF BACTERIOLOGY