VapC Toxins from Mycobacterium tuberculosis Are Ribonucleases that Differentially Inhibit Growth and Are Neutralized by Cognate VapB Antitoxins

Enteric virulence associated protein VapC inhibits translation by cleavage of initiator tRNA

(2011) K. S. Winther et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Triazaspirodimethoxybenzoyls as Selective Inhibitors of Mycobacterial Lipoamide Dehydrogenase,

(2010) Ruslana Bryk et al.   BIOCHEMISTRY

The Three RelE Homologs of Mycobacterium tuberculosis Have Individual, Drug-Specific Effects on Bacterial Antibiotic Tolerance

(2010) R. Singh et al.   JOURNAL OF BACTERIOLOGY

Spectrum of latent tuberculosis — existing tests cannot resolve the underlying phenotypes: author's reply

(2010) Clifton E. Barry et al.   NATURE REVIEWS MICROBIOLOGY

The PIN-domain ribonucleases and the prokaryotic VapBC toxin-antitoxin array

(2010) V. L. Arcus et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Mycobacterial survival strategies in the phagosome: defence against host stresses

(2009) Sabine Ehrt et al.   CELLULAR MICROBIOLOGY

The vapBC Operon from Mycobacterium smegmatis Is An Autoregulated Toxin–Antitoxin Module That Controls Growth via Inhibition of Translation

(2009) Jennifer Robson et al.   JOURNAL OF MOLECULAR BIOLOGY

Comprehensive Functional Analysis of Mycobacterium tuberculosis Toxin-Antitoxin Systems: Implications for Pathogenesis, Stress Responses, and Evolution

(2009) Holly R. Ramage et al.   PLoS Genetics

Role of Global Regulators and Nucleotide Metabolism in Antibiotic Tolerance in Escherichia coli

(2008) S. Hansen et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Selective Killing of Nonreplicating Mycobacteria

(2008) Ruslana Bryk et al.   Cell Host & Microbe

Biochemical characterization of a chromosomal toxin-antitoxin system inMycobacterium tuberculosis

(2008) Longxuan Zhao et al.   FEBS LETTERS

Killing activity and rescue function of genome-wide toxin–antitoxin loci ofMycobacterium tuberculosis

(2008) Amita Gupta   FEMS MICROBIOLOGY LETTERS

Function and Regulation of Class I Ribonucleotide Reductase-Encoding Genes in Mycobacteria

(2008) Mohube B. Mowa et al.   JOURNAL OF BACTERIOLOGY

Acid-Susceptible Mutants of Mycobacterium tuberculosis Share Hypersusceptibility to Cell Wall and Oxidative Stress and to the Host Environment

(2008) O. H. Vandal et al.   JOURNAL OF BACTERIOLOGY

Structure and Proposed Activity of a Member of the VapBC Family of Toxin-Antitoxin Systems

(2008) Linda Miallau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biosynthesis and Recycling of Nicotinamide Cofactors inMycobacterium tuberculosis

(2008) Helena I. M. Boshoff et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Confronting the scientific obstacles to global control of tuberculosis

(2008) Douglas B. Young et al.   JOURNAL OF CLINICAL INVESTIGATION

Crystal Structure of Mycobacterium tuberculosis YefM Antitoxin Reveals that it is Not an Intrinsically Unstructured Protein

(2008) Pramod Kumar et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural Mechanism of Transcriptional Autorepression of the Escherichia coli RelB/RelE Antitoxin/Toxin Module

(2008) Guang-Yao Li et al.   JOURNAL OF MOLECULAR BIOLOGY

Crystal structure of PAE0151 fromPyrobaculum aerophilum, a PIN-domain (VapC) protein from a toxin-antitoxin operon

(2008) Richard D. Bunker et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

PA-824 Kills Nonreplicating Mycobacterium tuberculosis by Intracellular NO Release

(2008) R. Singh et al.   SCIENCE

A new Gateway® vector and expression protocol for fast and efficient recombinant protein expression in Mycobacterium smegmatis

(2007) Rachael M. Goldstone et al.   PROTEIN EXPRESSION AND PURIFICATION