Research progress on the mechanism of ferroptosis and its role in diabetic retinopathy

Mitochondrial glutathione peroxidase 4 is indispensable for photoreceptor development and survival in mice

(2022) Kunihiro Azuma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A novel miR-338-3p/SLC1A5 axis reprograms retinal pigment epithelium to increases its resistance to high glucose-induced cell ferroptosis

(2022) Jing Zhou et al.   JOURNAL OF MOLECULAR HISTOLOGY

Downregulation of fatty acid binding protein 4 alleviates lipid peroxidation and oxidative stress in diabetic retinopathy by regulating peroxisome proliferator-activated receptor γ-mediated ferroptosis

(2022) Xiao’e Fan et al.   Bioengineered

Astragaloside-IV alleviates high glucose-induced ferroptosis in retinal pigment epithelial cells by disrupting the expression of miR-138-5p/Sirt1/Nrf2

(2022) Xuyuan Tang et al.   Bioengineered

Glia maturation factor-β induces ferroptosis by impairing chaperone-mediated autophagic degradation of ACSL4 in early diabetic retinopathy

(2022) Caiying Liu et al.   Redox Biology

Hypoxia aggravates ferroptosis in RPE cells by promoting the Fenton reaction

(2022) Yoshiyuki Henning et al.   Cell Death & Disease

lncRNA ZFAS1 Positively Facilitates Endothelial Ferroptosis via miR-7-5p/ACSL4 Axis in Diabetic Retinopathy

(2022) Yu Liu et al.   Oxidative Medicine and Cellular Longevity

TRIM46 aggravated high glucose-induced hyper permeability and inflammatory response in human retinal capillary endothelial cells by promoting IκBα ubiquitination

(2022) Hangqi Shen et al.   Eye and Vision

Ferroptosis: mechanisms, biology and role in disease

(2021) Xuejun Jiang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Role of ferroptosis in the process of diabetes-induced endothelial dysfunction

(2021) Er-Fei Luo et al.   World Journal of Diabetes

Anti-VEGF Crunch Syndrome in Proliferative Diabetic Retinopathy: A Review

(2021) Yiran Tan et al.   SURVEY OF OPHTHALMOLOGY

Lipid Metabolism and Ferroptosis

(2021) Ji-Yoon Lee et al.   Biology-Basel

Ferrostatin-1 attenuates ferroptosis and protects the retina against light-induced retinal degeneration

(2021) Wenyi Tang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

TRIM46 contributes to high glucose-induced ferroptosis and cell growth inhibition in human retinal capillary endothelial cells by facilitating GPX4 ubiquitination

(2021) Jingfa Zhang et al.   EXPERIMENTAL CELL RESEARCH

Microglia and macrophage exhibit attenuated inflammatory response and ferroptosis resistance after RSL3 stimulation via increasing Nrf2 expression

(2021) Yu Cui et al.   Journal of Neuroinflammation

Downregulation of Circular RNA PSEN1 ameliorates ferroptosis of the high glucose treated retinal pigment epithelial cells via miR-200b-3p/cofilin-2 axis

(2021) Zhaoliang Zhu et al.   Bioengineered

Ferroptosis, a novel pharmacological mechanism of anti-cancer drugs

(2020) Yanwei Su et al.   CANCER LETTERS

Involvement of regulated necrosis in blinding diseases: Focus on necroptosis and ferroptosis

(2020) Jing-Jie Peng et al.   EXPERIMENTAL EYE RESEARCH

Ferroptosis: past, present and future

(2020) Jie Li et al.   Cell Death & Disease

Inflammatory and angiogenic biomarkers in diabetic retinopathy

(2020) Snježana Kaštelan et al.   Biochemia Medica

Inhibition of fatty acid binding protein 4 attenuates gestational diabetes mellitus

(2020) Xiujuan Dong et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Friedreich Ataxia: current state-of-the-art, and future prospects for mitochondrial-focused therapies

(2020) Federico V. Pallardó et al.   Translational Research

CircRNA Is a Rising Star in Researches of Ocular Diseases

(2020) Chengshou Zhang et al.   Frontiers in Cell and Developmental Biology

Dominant optic atrophy: Culprit mitochondria in the optic nerve

(2020) Guy Lenaers et al.   PROGRESS IN RETINAL AND EYE RESEARCH

The molecular machinery of regulated cell death

(2019) Daolin Tang et al.   CELL RESEARCH

Ocular mucous membrane pemphigoid: a review

(2019) Samanta Taurone et al.   IMMUNOLOGIC RESEARCH

The Impact of Iron Overload and Ferroptosis on Reproductive Disorders in Humans: Implications for Preeclampsia

(2019) Shu-Wing Ng et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

RNA-Seq Revealed Novel Non-proliferative Retinopathy Specific Circulating MiRNAs in T2DM Patients

(2019) Zimeng Li et al.   Frontiers in Genetics

Circulating miR-3197 and miR-2116-5p as novel biomarkers for diabetic retinopathy

(2019) Huihui Ji et al.   CLINICA CHIMICA ACTA

Oxidative Stress and Microvascular Alterations in Diabetic Retinopathy: Future Therapies

(2019) María L. Rodríguez et al.   Oxidative Medicine and Cellular Longevity

Auranofin Mediates Mitochondrial Dysregulation and Inflammatory Cell Death in Human Retinal Pigment Epithelial Cells: Implications of Retinal Neurodegenerative Diseases

(2019) Thangal Yumnamcha et al.   Frontiers in Neuroscience

Insight into the mechanism of ferroptosis inhibition by ferrostatin-1

(2019) Giovanni Miotto et al.   Redox Biology

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

(2018) Lorenzo Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Mitophagy and Quality Control Mechanisms in Mitochondrial Maintenance

(2018) Sarah Pickles et al.   CURRENT BIOLOGY

Mitochondrial Antioxidants and the Maintenance of Cellular Hydrogen Peroxide Levels

(2018) Ryan J. Mailloux   Oxidative Medicine and Cellular Longevity

Glutathione depletion induces ferroptosis, autophagy, and premature cell senescence in retinal pigment epithelial cells

(2018) Yun Sun et al.   Cell Death & Disease

Unsolved mysteries: How does lipid peroxidation cause ferroptosis?

(2018) Huizhong Feng et al.   PLOS BIOLOGY

The Oxidative Stress and Mitochondrial Dysfunction during the Pathogenesis of Diabetic Retinopathy

(2018) Meng-Yu Wu et al.   Oxidative Medicine and Cellular Longevity

Diabetic retinopathy: a complex pathophysiology requiring novel therapeutic strategies

(2018) Michael Whitehead et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

The pathology associated with diabetic retinopathy

(2017) Judith Lechner et al.   VISION RESEARCH

Effects of diabetic retinopathy on the barrier functions of the retinal pigment epithelium

(2017) Tina Xia et al.   VISION RESEARCH

Anti-inflammatory Agents in the Treatment of Diabetes and Its Vascular Complications

(2016) Rena M. Pollack et al.   DIABETES CARE

Targeting Programmed Cell Death Using Small-Molecule Compounds to Improve Potential Cancer Therapy

(2016) Bowen Ke et al.   MEDICINAL RESEARCH REVIEWS

Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis

(2016) Wan Seok Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ferroptosis: Death by Lipid Peroxidation

(2016) Wan Seok Yang et al.   TRENDS IN CELL BIOLOGY

Acetylation Is Crucial for p53-Mediated Ferroptosis and Tumor Suppression

(2016) Shang-Jui Wang et al.   Cell Reports

Ferroptosis as a p53-mediated activity during tumour suppression

(2015) Le Jiang et al.   NATURE

Regulation of Ferroptotic Cancer Cell Death by GPX4

(2014) Wan Seok Yang et al.   CELL

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

(2014) L Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

(2014) Jose Pedro Friedmann Angeli et al.   NATURE CELL BIOLOGY

Efficacy of Anti-VEGF and Laser Photocoagulation in the Treatment of Visual Impairment due to Diabetic Macular Edema: A Systematic Review and Network Meta-Analysis

(2014) Stephane Régnier et al.   PLoS One

Pharmacological inhibition of cystine–glutamate exchange induces endoplasmic reticulum stress and ferroptosis

(2014) Scott J Dixon et al.   eLife

Role of advanced glycation end products in cellular signaling

(2014) Christiane Ott et al.   Redox Biology

Role of Nrf2 in Oxidative Stress and Toxicity

(2013) Qiang Ma   Annual Review of Pharmacology and Toxicology

The regulation of iron transport

(2013) David M. Frazer et al.   BIOFACTORS

Plasma kallikrein-kinin system and diabetic retinopathy

(2013) Jia Liu et al.   BIOLOGICAL CHEMISTRY

Iron-dependent cell death of hepatocellular carcinoma cells exposed to sorafenib

(2013) Christophe Louandre et al.   INTERNATIONAL JOURNAL OF CANCER

Pathophysiology and treatment of diabetic retinopathy

(2012) Francesco Bandello et al.   ACTA DIABETOLOGICA

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Protein Kinase C  Phosphorylates Occludin Regulating Tight Junction Trafficking in Vascular Endothelial Growth Factor-Induced Permeability In Vivo

(2012) T. Murakami et al.   DIABETES

Regulation of iron transport and the role of transferrin

(2011) Konstantinos Gkouvatsos et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

System xc- cystine/glutamate antiporter: an update on molecular pharmacology and roles within the CNS

(2011) Richard J Bridges et al.   BRITISH JOURNAL OF PHARMACOLOGY

Glutathione Peroxidase 4 Is Required for Maturation of Photoreceptor Cells

(2011) Takashi Ueta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Distinct Mechanisms of Ferritin Delivery to Lysosomes in Iron-Depleted and Iron-Replete Cells

(2011) T. Asano et al.   MOLECULAR AND CELLULAR BIOLOGY

The PKCβ/HuR/VEGF pathway in diabetic retinopathy

(2010) M. Amadio et al.   BIOCHEMICAL PHARMACOLOGY

Vascular NAD(P)H oxidase activation in diabetes: a double-edged sword in redox signalling

(2009) L. Gao et al.   CARDIOVASCULAR RESEARCH

Thioredoxin interacting protein (TXNIP) induces inflammation through chromatin modification in retinal capillary endothelial cells under diabetic conditions

(2009) Lorena Perrone et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Glutaredoxin Regulates Autocrine and Paracrine Proinflammatory Responses in Retinal Glial (Müller) Cells

(2008) Melissa D. Shelton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY