Angelica acutiloba Kitagawa flower induces A549 cell pyroptosis via the NF-κB/NLRP3 pathway for anti-lung cancer effects

Targeting Src reactivates pyroptosis to reverse chemoresistance in lung and pancreatic cancer models

(2023) Liangping Su et al.   Science Translational Medicine

Role of mitochondrial stress and the NLRP3 inflammasome in lung diseases

(2023) Yonghu Chen et al.   INFLAMMATION RESEARCH

Cancer statistics, 2022

(2022) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Angelica acutiloba Exerts Antihypertensive Effect and Improves Insulin Resistance in Spontaneously Hypertensive Rats Fed with a High-Fat Diet

(2022) Yusuke Watanabe et al.   PHARMACOLOGY

Ophiopogonin B alleviates cisplatin resistance of lung cancer cells by inducing Caspase-1/GSDMD dependent pyroptosis

(2022) Ziyu Cheng et al.   Journal of Cancer

Vagus nerve stimulation alleviated cerebral ischemia and reperfusion injury in rats by inhibiting pyroptosis via α7 nicotinic acetylcholine receptor

(2022) Hao Tang et al.   Cell Death Discovery

A pyroptosis nanotuner for cancer therapy

(2022) Binlong Chen et al.   Nature Nanotechnology

Modafinil Reduces Neuronal Pyroptosis and Cognitive Decline After Sleep Deprivation

(2022) Xiangyang Xiong et al.   Frontiers in Neuroscience

Comprehensive Analysis of CDK1-Associated ceRNA Network Revealing the Key Pathways LINC00460/LINC00525-Hsa-Mir-338-FAM111/ZWINT as Prognostic Biomarkers in Lung Adenocarcinoma Combined with Experiments

(2022) Wen Li et al.   Cells

Selenium Yeast and Fish Oil Combination Diminishes Cancer Stem Cell Traits and Reverses Cisplatin Resistance in A549 Sphere Cells

(2022) I-Chun Lai et al.   Nutrients

A Novel Drug Combination of Mangiferin and Cinnamic Acid Alleviates Rheumatoid Arthritis by Inhibiting TLR4/NFκB/NLRP3 Activation-Induced Pyroptosis

(2022) Weijie Li et al.   Frontiers in Immunology

Cigarette smoke-induced gasdermin D activation in bronchoalveolar macrophages and bronchial epithelial cells dependently on NLRP3

(2022) Sarah Huot-Marchand et al.   Frontiers in Immunology

First report of apple latent spherical virus infecting Angelica sinensis

(2022) Weijie Jin et al.   PLANT DISEASE

Lactobacillus rhamnosus GR-1 attenuates foodborne Bacillus cereus-induced NLRP3 inflammasome activity in bovine mammary epithelial cells by protecting intercellular tight junctions

(2022) Qiang Shan et al.   Journal of Animal Science and Biotechnology

Identifying a lactic acid metabolism-related gene signature contributes to predicting prognosis, immunotherapy efficacy, and tumor microenvironment of lung adenocarcinoma

(2022) Fangchao  Zhao et al.   Frontiers in Immunology

Cancer Statistics, 2021

(2021) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Licochalcone A inhibits proliferation and promotes apoptosis of colon cancer cell by targeting programmed cell death-ligand 1 via the NF-κB and Ras/Raf/MEK pathways

(2021) Xueshuang Liu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Assessment of an Exhaled Breath Test Using High-Pressure Photon Ionization Time-of-Flight Mass Spectrometry to Detect Lung Cancer

(2021) Shushi Meng et al.   JAMA Network Open

The additive memory and healthspan enhancement effects by the combined treatment of mature silkworm powders and Korean angelica extracts

(2021) Phuong Nguyen et al.   JOURNAL OF ETHNOPHARMACOLOGY

The protective effect of quercetin on macrophage pyroptosis via TLR2/Myd88/NF-κB and ROS/AMPK pathway

(2021) Xing Luo et al.   LIFE SCIENCES

Anti‐Chi3L1 antibody suppresses lung tumor growth and metastasis through inhibition of M2 polarization

(2021) Ji Eun Yu et al.   Molecular Oncology

LPS-induced macrophage HMGB1-loaded extracellular vesicles trigger hepatocyte pyroptosis by activating the NLRP3 inflammasome

(2021) Guozhen Wang et al.   Cell Death Discovery

Ligustilide improves aging-induced memory deficit by regulating mitochondrial related inflammation in SAMP8 mice

(2020) Wen-Li Zhu et al.   Aging-US

Gemcitabine inhibits cisplatin resistance in cisplatin-resistant A549 cells by upregulating trx-interacting protein and inducing cell cycle arrest

(2020) Wenjie Cao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Sequential ubiquitination of NLRP3 by RNF125 and Cbl-b limits inflammasome activation and endotoxemia

(2020) Juan Tang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Glycyrrhizic‐Acid‐Based Carbon Dots with High Antiviral Activity by Multisite Inhibition Mechanisms

(2020) Ting Tong et al.   Small

Effect of Angelica gigas Nakai Ethanol Extract and Decursin on Human Pancreatic Cancer Cells

(2020) Bitna Kweon et al.   MOLECULES

FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation

(2020) Jun Jacob Hu et al.   NATURE IMMUNOLOGY

Granzyme A from cytotoxic lymphocytes cleaves GSDMB to trigger pyroptosis in target cells

(2020) Zhiwei Zhou et al.   SCIENCE

Flexible Usage and Interconnectivity of Diverse Cell Death Pathways Protect against Intracellular Infection

(2020) Marcel Doerflinger et al.   IMMUNITY

Caspase-11–mediated enteric neuronal pyroptosis underlies Western diet–induced colonic dysmotility

(2020) Lan Ye et al.   JOURNAL OF CLINICAL INVESTIGATION

Prevalence and attributable health burden of chronic respiratory diseases, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017

(2020) Joan B Soriano et al.   Lancet Respiratory Medicine

PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis

(2020) Junwei Hou et al.   NATURE CELL BIOLOGY

Chemical Fingerprint Analysis and Ultra-Performance Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry-Based Metabolomics Study of the Protective Effect of Buxue Yimu Granule in Medical-Induced Incomplete Abortion Rats

(2020) Yan Zhang et al.   Frontiers in Pharmacology

Mutant BRAF and MEK Inhibitors Regulate the Tumor Immune Microenvironment via Pyroptosis

(2019) Dan A. Erkes et al.   Cancer Discovery

The Japanese Angelica acutiloba root and yokukansan increase hippocampal acetylcholine level, prevent apoptosis and improve memory in a rat model of repeated cerebral ischemia

(2018) Ai Nogami-Hara et al.   JOURNAL OF ETHNOPHARMACOLOGY

Inflammasome Complexes: Emerging Mechanisms and Effector Functions

(2016) Vijay A.K. Rathinam et al.   CELL

The cellular thermal shift assay for evaluating drug target interactions in cells

(2014) Rozbeh Jafari et al.   Nature Protocols

Angelica acutiloba Root Attenuates Insulin Resistance Induced by High-Fructose Diet in Rats

(2011) I-Min Liu et al.   PHYTOTHERAPY RESEARCH