miR-20b-5p exerts protective effects against experimental autoimmune encephalomyelitis in mice by inhibiting NLRP3 transcription and NLRP3/ASC/caspase-1 axis activation

Human microRNA (miR-20b-5p) modulates Alzheimer’s disease pathways and neuronal function, and a specific polymorphism close to the MIR20B gene influences Alzheimer’s biomarkers

(2022) Ruizhi Wang et al.   MOLECULAR PSYCHIATRY

Effects of microRNA-298 on APP and BACE1 translation differ according to cell type and 3′-UTR variation

(2022) Ruizhi Wang et al.   Scientific Reports

The NLRP3 Inflammasome and Its Role in the Pathogenicity of Leukemia

(2021) Laura Urwanisch et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

MiR-599 Protects Cardiomyocytes against Oxidative Stress-Induced Pyroptosis

(2021) Xiaoying Fan et al.   Biomed Research International

MicroRNA-298 reduces levels of human amyloid-β precursor protein (APP), β-site APP-converting enzyme 1 (BACE1) and specific tau protein moieties

(2020) Nipun Chopra et al.   MOLECULAR PSYCHIATRY

Elevated microRNA‐20b‐3p and reduced thioredoxin‐interacting protein ameliorate diabetic retinopathy progression by suppressing the NLRP3 inflammasomes

(2020) Shuai Wang et al.   IUBMB LIFE

Inhibition of the NLRP3-inflammasome prevents cognitive deficits in experimental autoimmune encephalomyelitis mice via the alteration of astrocyte phenotype

(2020) Baohua Hou et al.   Cell Death & Disease

Sinomenine Alleviates Murine Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis through Inhibiting NLRP3 Inflammasome

(2020) Zahra Kiasalari et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Mechanisms of M2 Macrophage-Derived Exosomal Long Non-coding RNA PVT1 in Regulating Th17 Cell Response in Experimental Autoimmune Encephalomyelitisa

(2020) Lei Wu et al.   Frontiers in Immunology

Ellagic acid ameliorates neuroinflammation and demyelination in experimental autoimmune encephalomyelitis: Involvement of NLRP3 and pyroptosis

(2020) Zahra Kiasalari et al.   JOURNAL OF CHEMICAL NEUROANATOMY

Propofol directly induces caspase-1-dependent macrophage pyroptosis through the NLRP3-ASC inflammasome

(2019) Lingbin Sun et al.   Cell Death & Disease

Serum pro‐inflammatory and anti‐inflammatory cytokines and the pathogenesis of experimental autoimmune encephalomyelitis

(2019) Ali J. Jahan‐Abad et al.   NEUROPATHOLOGY

Ghrelin Attenuates Neuroinflammation and Demyelination in Experimental Autoimmune Encephalomyelitis Involving NLRP3 Inflammasome Signaling Pathway and Pyroptosis

(2019) Fei Liu et al.   Frontiers in Pharmacology

Jinxin oral liquid inhibits human respiratory syncytial virus-induced excessive inflammation associated with blockade of the NLRP3/ASC/Caspase-1 pathway

(2018) Cunsi Shen et al.   BIOMEDICINE & PHARMACOTHERAPY

lincRNA-Cox2 regulates NLRP3 inflammasome and autophagy mediated neuroinflammation

(2018) Zhenyi Xue et al.   CELL DEATH AND DIFFERENTIATION

Animal models of multiple sclerosis: Focus on experimental autoimmune encephalomyelitis

(2018) Ivana Bjelobaba et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Gut Microbiota in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis: Current Applications and Future Perspectives

(2018) Fengna Chu et al.   MEDIATORS OF INFLAMMATION

Nicotine promotes atherosclerosis via ROS-NLRP3-mediated endothelial cell pyroptosis

(2018) Xianxian Wu et al.   Cell Death & Disease

Experimental Autoimmune Encephalomyelitis (EAE) as Animal Models of Multiple Sclerosis (MS)

(2018) Simon Glatigny et al.   Cold Spring Harbor Perspectives in Medicine

Neuronal microRNA regulation in Experimental Autoimmune Encephalomyelitis

(2018) Camille A. Juźwik et al.   Scientific Reports

The mechanisms of NLRP3 inflammasome/pyroptosis activation and their role in Parkinson's disease

(2018) Shuo Wang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Exosomes derived from mesenchymal stem cells attenuate inflammation and demyelination of the central nervous system in EAE rats by regulating the polarization of microglia

(2018) Zijian Li et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

MiR-20b inhibits mycobacterium tuberculosis induced inflammation in the lung of mice through targeting NLRP3

(2017) Jun Lou et al.   EXPERIMENTAL CELL RESEARCH

Rapamycin Ameliorates Experimental Autoimmune Encephalomyelitis by Suppressing the mTOR-STAT3 Pathway

(2017) Huiqing Hou et al.   NEUROCHEMICAL RESEARCH

NLRP3 Inflammasome in Neurological Diseases, from Functions to Therapies

(2017) Limin Song et al.   Frontiers in Cellular Neuroscience

Multiple sclerosis: experimental models and reality

(2016) Hans Lassmann et al.   ACTA NEUROPATHOLOGICA

KIR4.1: K+ Channel Illusion or Reality in the Autoimmune Pathogenesis of Multiple Sclerosis

(2016) Chen Gu   Frontiers in Molecular Neuroscience

Experimental Autoimmune Encephalomyelitis Development Is Aggravated byCandida albicansInfection

(2015) Thais F. C. Fraga-Silva et al.   Journal of Immunology Research

Natalizumab restores aberrant miRNA expression profile in multiple sclerosis and reveals a critical role for miR-20b

(2015) Jens Ingwersen et al.   Annals of Clinical and Translational Neurology

miR-20b Suppresses Th17 Differentiation and the Pathogenesis of Experimental Autoimmune Encephalomyelitis by Targeting ROR t and STAT3

(2014) E. Zhu et al.   JOURNAL OF IMMUNOLOGY

An ανβ3 Integrin-Binding Peptide Ameliorates Symptoms of Chronic Progressive Experimental Autoimmune Encephalomyelitis by Alleviating Neuroinflammatory Responses in Mice

(2014) Fan Zhang et al.   Journal of Neuroimmune Pharmacology

The role of miRNA in inflammation and autoimmunity

(2013) Ram Pyare Singh et al.   AUTOIMMUNITY REVIEWS

Experimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS)

(2011) Cris S Constantinescu et al.   BRITISH JOURNAL OF PHARMACOLOGY

Role of microRNAs in central nervous system development and pathology

(2011) Karla F. Meza-Sosa et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Infiltration of Th1 and Th17 cells and activation of microglia in the CNS during the course of experimental autoimmune encephalomyelitis

(2010) Áine C. Murphy et al.   BRAIN BEHAVIOR AND IMMUNITY

T cells in multiple sclerosis and experimental autoimmune encephalomyelitis

(2010) J. M. Fletcher et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Cutting Edge: Critical Role for PYCARD/ASC in the Development of Experimental Autoimmune Encephalomyelitis

(2010) P. J. Shaw et al.   JOURNAL OF IMMUNOLOGY

MicroRNAs: new regulators of immune cell development and function

(2008) David Baltimore et al.   NATURE IMMUNOLOGY