Human microRNA (miR-20b-5p) modulates Alzheimer’s disease pathways and neuronal function, and a specific polymorphism close to the MIR20B gene influences Alzheimer’s biomarkers
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Human microRNA (miR-20b-5p) modulates Alzheimer’s disease pathways and neuronal function, and a specific polymorphism close to the MIR20B gene influences Alzheimer’s biomarkers
Authors
Keywords
-
Journal
MOLECULAR PSYCHIATRY
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2022-01-27
DOI
10.1038/s41380-021-01351-3
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Repeated electromagnetic field stimulation lowers amyloid-β peptide levels in primary human mixed brain tissue cultures
- (2021) Felipe P. Perez et al. Scientific Reports
- Defining the functional divergence of orthologous genes between human and mouse in the context of miRNA regulation
- (2021) Chunmei Cui et al. BRIEFINGS IN BIOINFORMATICS
- BACE1 controls synaptic function through modulating release of synaptic vesicles
- (2021) Brati Das et al. MOLECULAR PSYCHIATRY
- Treatments for Alzheimer's disease emerge
- (2021) Dennis J. Selkoe SCIENCE
- Therapy based on functional RNA elements
- (2021) Rotem Ben-Tov Perry et al. SCIENCE
- MicroRNA-298 reduces levels of human amyloid-β precursor protein (APP), β-site APP-converting enzyme 1 (BACE1) and specific tau protein moieties
- (2020) Nipun Chopra et al. MOLECULAR PSYCHIATRY
- Rivastigmine modifies the α-secretase pathway and potentially early Alzheimer’s disease
- (2020) Balmiki Ray et al. Translational Psychiatry
- MicroRNA-195 rescues ApoE4-induced cognitive deficits and lysosomal defects in Alzheimer’s disease pathogenesis
- (2020) Jiqing Cao et al. MOLECULAR PSYCHIATRY
- Amyloid-β Precursor Protein APP Down-Regulation Alters Actin Cytoskeleton-Interacting Proteins in Endothelial Cells
- (2020) Emma Ristori et al. Cells
- miR-20b, miR-296, and Let-7f Expression in Human Adipose Tissue is Related to Obesity and Type 2 Diabetes
- (2019) Adriana-Mariel Gentile et al. Obesity
- MicroRNA‑20b promotes proliferation of H22 hepatocellular carcinoma cells by targeting PTEN
- (2019) Jing He et al. Oncology Letters
- Regulation of BTG3 by microRNA‑20b‑5p in non‑small cell lung cancer
- (2019) Lijun Peng et al. Oncology Letters
- Novel Contribution of Secreted Amyloid-β Precursor Protein to White Matter Brain Enlargement in Autism Spectrum Disorder
- (2019) Deborah K. Sokol et al. Frontiers in Psychiatry
- Amyloid-beta modulates low-threshold activated voltage-gated L-type calcium channels of arcuate neuropeptide Y neurons leading to calcium dysregulation and hypothalamic dysfunction
- (2019) Makoto Ishii et al. JOURNAL OF NEUROSCIENCE
- A New Discovery of MicroRNA-455-3p in Alzheimer’s Disease
- (2019) Subodh Kumar et al. JOURNAL OF ALZHEIMERS DISEASE
- Questions EMERGE as Biogen claims aducanumab turnaround
- (2019) Robert Howard et al. Nature Reviews Neurology
- Circulating Exosomal miR‐20b‐5p Inhibition Restores Wnt9b Signaling and Reverses Diabetes‐Associated Impaired Wound Healing
- (2019) Yuan Xiong et al. Small
- Lithium alters expression of RNAs in a type-specific manner in differentiated human neuroblastoma neuronal cultures, including specific genes involved in Alzheimer’s disease
- (2019) Bryan Maloney et al. Scientific Reports
- NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease
- (2018) Clifford R. Jack et al. Alzheimers & Dementia
- ApoE isoforms and carboxyl-terminal-truncated apoE4 forms affect neuronal BACE1 levels and Aβ production independently of their cholesterol efflux capacity
- (2018) Ioannis Dafnis et al. BIOCHEMICAL JOURNAL
- Circulating microRNAs from the miR-106a–363 cluster on chromosome X as novel diagnostic biomarkers for breast cancer
- (2018) Minghui Li et al. BREAST CANCER RESEARCH AND TREATMENT
- Amyloid Precursor Protein Dimerisation Reduces Neurite Outgrowth
- (2018) Luan Luu et al. MOLECULAR NEUROBIOLOGY
- Knockout of Amyloid β Protein Precursor (APP) Expression Alters Synaptogenesis, Neurite Branching and Axonal Morphology of Hippocampal Neurons
- (2018) Katherine A. Southam et al. NEUROCHEMICAL RESEARCH
- Perspectives on ethnic and racial disparities in Alzheimer's disease and related dementias: Update and areas of immediate need
- (2018) Ganesh M. Babulal et al. Alzheimers & Dementia
- Circulating Exosomal miR-20b-5p is Elevated in Type 2 Diabetes and Could Impair Insulin Action in Human Skeletal Muscle
- (2018) Mutsumi Katayama et al. DIABETES
- Downregulation of miR-20b-5p facilitates Mycobacterium tuberculosis survival in RAW 264.7 macrophages via attenuating the cell apoptosis by Mcl-1 upregulation
- (2018) Defeng Zhang et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Novel upregulation of amyloid-β precursor protein (APP) by microRNA-346 via targeting of APP mRNA 5′-untranslated region: Implications in Alzheimer’s disease
- (2018) Justin M. Long et al. MOLECULAR PSYCHIATRY
- Are pulmonary fibrosis and Alzheimer's disease linked? Shared dysregulation of two miRNA species and downstream pathways accompany both disorders
- (2017) Debomoy K. Lahiri et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Primary Cell Culture of Live Neurosurgically Resected Aged Adult Human Brain Cells and Single Cell Transcriptomics
- (2017) Jennifer M. Spaethling et al. Cell Reports
- Amyloid-β1–40 Inhibits Amyloid-β1–42 Induced Activation of Cytoplasmic Phospholipase A2 and Synapse Degeneration
- (2017) Clive Bate et al. JOURNAL OF ALZHEIMERS DISEASE
- MiR-20b targets AKT3 and modulates vascular endothelial growth factor-mediated changes in diabetic retinopathy
- (2016) Bo Qin et al. ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- CSF and blood biomarkers for the diagnosis of Alzheimer's disease: a systematic review and meta-analysis
- (2016) Bob Olsson et al. LANCET NEUROLOGY
- Epigenetics of dementia: understanding the disease as a transformation rather than a state
- (2016) Bryan Maloney et al. LANCET NEUROLOGY
- Novel roles of amyloid-beta precursor protein metabolites in fragile X syndrome and autism
- (2016) C J Westmark et al. MOLECULAR PSYCHIATRY
- MicroRNA-20b Downregulates HIF-1α and Inhibits the Proliferation and Invasion of Osteosarcoma Cells
- (2016) Ming Liu et al. ONCOLOGY RESEARCH
- Different levels of serum microRNAs in prostate cancer and benign prostatic hyperplasia: evaluation of potential diagnostic and prognostic role
- (2016) Giovanni Cochetti et al. OncoTargets and Therapy
- Finding novel distinctions between the sAPPα-mediated anabolic biochemical pathways in Autism Spectrum Disorder and Fragile X Syndrome plasma and brain tissue
- (2016) Balmiki Ray et al. Scientific Reports
- Plasma levels of apolipoprotein E and risk of dementia in the general population
- (2015) Katrine L. Rasmussen et al. ANNALS OF NEUROLOGY
- 3,3′-Diindolylmethane attenuates LPS-mediated acute liver failure by regulating miRNAs to target IRAK4 and suppress Toll-like receptor signalling
- (2015) S Tomar et al. BRITISH JOURNAL OF PHARMACOLOGY
- Evidence for a neuroprotective microRNA pathway in amnestic mild cognitive impairment
- (2015) Rebecca B. Weinberg et al. Frontiers in Neuroscience
- Preclinical Evaluation of miR-15/107 Family Members as Multifactorial Drug Targets for Alzheimer's Disease
- (2015) Sepideh Parsi et al. Molecular Therapy-Nucleic Acids
- CSF Apo-E levels associate with cognitive decline and MRI changes
- (2014) Jon B. Toledo et al. ACTA NEUROPATHOLOGICA
- APOE and mild cognitive impairment: the Framingham Heart Study
- (2014) Angela L. Jefferson et al. AGE AND AGEING
- Lessons from a BACE1 inhibitor trial: Off-site but not off base
- (2014) Debomoy K. Lahiri et al. Alzheimers & Dementia
- MiR-20b, -21, and -130b inhibit PTEN expression resulting in B7-H1 over-expression in advanced colorectal cancer
- (2014) Jianjie Zhu et al. HUMAN IMMUNOLOGY
- MicroRNA-384 regulates both amyloid precursor protein and β-secretase expression and is a potential biomarker for Alzheimer’s disease
- (2014) CHEN-GENG LIU et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- miR-20b Suppresses Th17 Differentiation and the Pathogenesis of Experimental Autoimmune Encephalomyelitis by Targeting ROR t and STAT3
- (2014) E. Zhu et al. JOURNAL OF IMMUNOLOGY
- Differential Release of -Amyloid from Dendrite- Versus Axon-Targeted APP
- (2014) S. R. DeBoer et al. JOURNAL OF NEUROSCIENCE
- miR-20b regulates expression of proteinase-activated receptor-1 (PAR-1) thrombin receptor in melanoma cells
- (2014) Amina Saleiban et al. Pigment Cell & Melanoma Research
- Human primary mixed brain cultures: preparation, differentiation, characterization and application to neuroscience research
- (2014) Balmiki Ray et al. Molecular Brain
- The miR-17/92 cluster: a comprehensive update on its genomics, genetics, functions and increasingly important and numerous roles in health and disease
- (2013) E Mogilyansky et al. CELL DEATH AND DIFFERENTIATION
- Dosage of amyloid precursor protein affects axonal contact guidance in Down syndrome
- (2013) Lucas J. Sosa et al. FASEB JOURNAL
- MicroRNA-339-5p Down-regulates Protein Expression of β-Site Amyloid Precursor Protein-Cleaving Enzyme 1 (BACE1) in Human Primary Brain Cultures and Is Reduced in Brain Tissue Specimens of Alzheimer Disease Subjects
- (2013) Justin M. Long et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Amyloid precursor proteins are constituents of the presynaptic active zone
- (2013) Melanie Laßek et al. JOURNAL OF NEUROCHEMISTRY
- Reversible Pathologic and Cognitive Phenotypes in an Inducible Model of Alzheimer-Amyloidosis
- (2013) T. Melnikova et al. JOURNAL OF NEUROSCIENCE
- ApoE influences amyloid- (A ) clearance despite minimal apoE/A association in physiological conditions
- (2013) P. B. Verghese et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Trafficking and Proteolytic Processing of APP
- (2013) C. Haass et al. Cold Spring Harbor Perspectives in Medicine
- The Alzheimer’s Disease Assessment Scale-Cognitive-Plus (ADAS-Cog-Plus): an expansion of the ADAS-Cog to improve responsiveness in MCI
- (2012) Jeannine Skinner et al. Brain Imaging and Behavior
- MicroRNA-153 Physiologically Inhibits Expression of Amyloid-β Precursor Protein in Cultured Human Fetal Brain Cells and Is Dysregulated in a Subset of Alzheimer Disease Patients
- (2012) Justin M. Long et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Preeclampsia Up-Regulates Angiogenesis-Associated MicroRNA (i.e., miR-17, -20a, and -20b) That Target Ephrin-B2 and EPHB4 in Human Placenta
- (2012) Wen Wang et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Novel G S-Protein Signaling Associated with Membrane-Tethered Amyloid Precursor Protein Intracellular Domain
- (2012) C. Deyts et al. JOURNAL OF NEUROSCIENCE
- Alveolar Macrophage-Derived Vascular Endothelial Growth Factor Contributes to Allergic Airway Inflammation in a Mouse Asthma Model
- (2012) C. Song et al. SCANDINAVIAN JOURNAL OF IMMUNOLOGY
- Current Drug Targets for Modulating Alzheimer's Amyloid Precursor Protein: Role of Specific Micro-RNA Species
- (2011) J.M. Long et al. CURRENT MEDICINAL CHEMISTRY
- Increased Secreted Amyloid Precursor Protein-α (sAPPα) in Severe Autism: Proposal of a Specific, Anabolic Pathway and Putative Biomarker
- (2011) Balmiki Ray et al. PLoS One
- Amyloid Precursor Protein Is Trafficked and Secreted via Synaptic Vesicles
- (2011) Teja W. Groemer et al. PLoS One
- Endogenous amyloid-β is necessary for hippocampal synaptic plasticity and memory
- (2010) Daniela Puzzo et al. ANNALS OF NEUROLOGY
- MicroRNA-101 downregulates Alzheimer’s amyloid-β precursor protein levels in human cell cultures and is differentially expressed
- (2010) Justin M. Long et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Genetic ablation of Dicer in adult forebrain neurons results in abnormal tau hyperphosphorylation and neurodegeneration
- (2010) Sébastien S. Hébert et al. HUMAN MOLECULAR GENETICS
- MicroRNA-16 targets amyloid precursor protein to potentially modulate Alzheimer's-associated pathogenesis in SAMP8 mice
- (2010) Wei Liu et al. NEUROBIOLOGY OF AGING
- Increased expression of miRNA-146a in Alzheimer's disease transgenic mouse models
- (2010) Y.Y. Li et al. NEUROSCIENCE LETTERS
- Combined mRNA and microRNA profiling reveals that miR-148a and miR-20b control human mesenchymal stem cell phenotype via EPAS1
- (2010) Karine Giraud-Triboult et al. PHYSIOLOGICAL GENOMICS
- Coefficients of Determination in Logistic Regression Models—A New Proposal: The Coefficient of Discrimination
- (2009) Tue Tjur AMERICAN STATISTICIAN
- Amyloid precursor protein 695 associates with assembled NR2A- and NR2B-containing NMDA receptors to result in the enhancement of their cell surface delivery
- (2009) Sarah L. Cousins et al. JOURNAL OF NEUROCHEMISTRY
- Expression of Human Amyloid Precursor Protein in Rat Cortical Neurons Inhibits Calcium Oscillations
- (2009) S. F. Santos et al. JOURNAL OF NEUROSCIENCE
- Interaction of Reelin with Amyloid Precursor Protein Promotes Neurite Outgrowth
- (2009) H.-S. Hoe et al. JOURNAL OF NEUROSCIENCE
- MicroRNA regulation of Alzheimer's Amyloid precursor protein expression
- (2008) Sébastien S. Hébert et al. NEUROBIOLOGY OF DISEASE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now