Refactoring the architecture of a polyketide gene cluster enhances docosahexaenoic acid production in Yarrowia lipolytica through improved expression and genetic stability
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Title
Refactoring the architecture of a polyketide gene cluster enhances docosahexaenoic acid production in Yarrowia lipolytica through improved expression and genetic stability
Authors
Keywords
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Journal
Microbial Cell Factories
Volume 22, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2023-09-29
DOI
10.1186/s12934-023-02209-9
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Note: Only part of the references are listed.- Systems metabolic engineering upgrades Corynebacterium glutamicum for selective high-level production of the chiral drug precursor and cell-protective extremolyte L-pipecolic acid
- (2023) Sarah Pauli et al. METABOLIC ENGINEERING
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- (2023) Jens Christmann et al. Microbial Cell Factories
- Identification and Construction of Strong Promoters in Yarrowia lipolytica Suitable for Glycerol-Based Bioprocesses
- (2023) Ioannis Georgiadis et al. Microorganisms
- Multi-omics view of recombinant Yarrowia lipolytica: Enhanced ketogenic amino acid catabolism increases polyketide-synthase-driven docosahexaenoic production to high selectivity at the gram scale
- (2023) Sofija Jovanovic Gasovic et al. METABOLIC ENGINEERING
- Practical genetic control strategies for industrial bioprocesses
- (2022) Jonathan C Moore et al. JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
- Advancing Yarrowia lipolytica as a superior biomanufacturing platform by tuning gene expression using promoter engineering
- (2022) Mei-Li Sun et al. BIORESOURCE TECHNOLOGY
- Synthesis of Secretory Proteins in Yarrowia lipolytica: Effect of Combined Stress Factors and Metabolic Load
- (2022) Maria Gorczyca et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Biobased PET from lignin using an engineered cis, cis-muconate-producing Pseudomonas putida strain with superior robustness, energy and redox properties
- (2022) Michael Kohlstedt et al. METABOLIC ENGINEERING
- Systems metabolic engineering of Corynebacterium glutamicum eliminates all by-products for selective and high-yield production of the platform chemical 5-aminovalerate
- (2022) Christina Rohles et al. METABOLIC ENGINEERING
- Systems metabolic engineering upgrades Corynebacterium glutamicum to high-efficiency cis, cis-muconic acid production from lignin-based aromatics
- (2022) Fabia Weiland et al. METABOLIC ENGINEERING
- Engineering of Yarrowia lipolytica for terpenoid production
- (2022) Jonathan Asmund Arnesen et al. Metabolic Engineering Communications
- Development of a CRISPR/Cas9-mediated homology-independent tool for targeted genome integration in Yarrowia lipolytica
- (2021) Zhiyong Cui et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Microparticles enhance the formation of seven major classes of natural products in native and metabolically engineered actinobacteria through accelerated morphological development
- (2021) Martin Kuhl et al. BIOTECHNOLOGY AND BIOENGINEERING
- Refactoring biosynthetic gene clusters for heterologous production of microbial natural products
- (2021) Lei Li et al. CURRENT OPINION IN BIOTECHNOLOGY
- Microbial production of polyunsaturated fatty acids — high-value ingredients for aquafeed, superfoods, and pharmaceuticals
- (2021) Sofija Jovanovic et al. CURRENT OPINION IN BIOTECHNOLOGY
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- (2021) Sarah Lisa Hoffmann et al. METABOLIC ENGINEERING
- Superior production of heavy pamamycin derivatives using a bkdR deletion mutant of Streptomyces albus J1074/R2
- (2021) Lars Gläser et al. Microbial Cell Factories
- Health benefits of docosahexaenoic acid and its bioavailability: A review
- (2021) Jia Li et al. Food Science & Nutrition
- A modular pathway engineering strategy for the high-level production of β-ionone in Yarrowia lipolytica
- (2020) Yanping Lu et al. Microbial Cell Factories
- Optimization of Yarrowia lipolytica-based consolidated biocatalyst through synthetic biology approach: transcription units and signal peptides shuffling
- (2020) Ewelina Celińska et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- A common approach for absolute quantification of short chain CoA thioesters in prokaryotic and eukaryotic microbes
- (2020) Lars Gläser et al. Microbial Cell Factories
- Microparticles globally reprogram Streptomyces albus toward accelerated morphogenesis, streamlined carbon core metabolism, and enhanced production of the antituberculosis polyketide pamamycin
- (2020) Martin Kuhl et al. BIOTECHNOLOGY AND BIOENGINEERING
- Yarrowia lipolytica Strains Engineered for the Production of Terpenoids
- (2020) Jonathan Asmund Arnesen et al. Frontiers in Bioengineering and Biotechnology
- Metabolic engineering of Corynebacterium glutamicum for high‐level ectoine production – design, combinatorial assembly and implementation of a transcriptionally balanced heterologous ectoine pathway
- (2019) Gideon Gießelmann et al. Biotechnology Journal
- Projected declines in global DHA availability for human consumption as a result of global warming
- (2019) Stefanie M. Colombo et al. AMBIO
- Polyunsaturated fatty acid production by Yarrowia lipolytica employing designed myxobacterial PUFA synthases
- (2019) Katja Gemperlein et al. Nature Communications
- Advances in synthetic biology of oleaginous yeast Yarrowia lipolytica for producing non-native chemicals
- (2018) Farshad Darvishi et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- EasyCloneYALI: CRISPR/Cas9-Based Synthetic Toolbox for Engineering of the Yeast Yarrowia lipolytica
- (2018) Carina Holkenbrink et al. Biotechnology Journal
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- (2018) Yu-Ying Huang et al. JOURNAL OF BIOTECHNOLOGY
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- (2018) Susanne Katharina Schwechheimer et al. METABOLIC ENGINEERING
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- (2018) Kelly A. Markham et al. TRENDS IN BIOTECHNOLOGY
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- (2018) Fereidoon Shahidi et al. Annual Review of Food Science and Technology
- Overproduction of Fatty Acid Ethyl Esters by the Oleaginous Yeast Yarrowia lipolytica through Metabolic Engineering and Process Optimization
- (2018) Qi Gao et al. ACS Synthetic Biology
- EasyCloneYALI: CRISPR/Cas9-Based Synthetic Toolbox for Engineering of the Yeast Yarrowia lipolytica
- (2018) Carina Holkenbrink et al. Biotechnology Journal
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- (2018) Lauren T. Cordova et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
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- (2016) Cory Schwartz et al. ACS Synthetic Biology
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- (2016) Rui M. C. Portela et al. ACS Synthetic Biology
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- (2016) Wenjiang Song et al. Journal of Biological Engineering
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- (2014) Qian Gao et al. JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY
- From zero to hero – Production of bio-based nylon from renewable resources using engineered Corynebacterium glutamicum
- (2014) Stefanie Kind et al. METABOLIC ENGINEERING
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- (2014) Katja Gemperlein et al. Chemical Science
- Yarrowia lipolytica: Safety assessment of an oleaginous yeast with a great industrial potential
- (2013) Marizeth Groenewald et al. CRITICAL REVIEWS IN MICROBIOLOGY
- Systems metabolic engineering of Escherichia coli for production of the antitumor drugs violacein and deoxyviolacein
- (2013) André L. Rodrigues et al. METABOLIC ENGINEERING
- Production of omega-3 eicosapentaenoic acid by metabolic engineering of Yarrowia lipolytica
- (2013) Zhixiong Xue et al. NATURE BIOTECHNOLOGY
- Production of EPA and DHA in aquatic ecosystems and their transfer to the land
- (2013) Michail I. Gladyshev et al. PROSTAGLANDINS & OTHER LIPID MEDIATORS
- Refactoring the Silent Spectinabilin Gene Cluster Using a Plug-and-Play Scaffold
- (2013) Zengyi Shao et al. ACS Synthetic Biology
- Engineering the push and pull of lipid biosynthesis in oleaginous yeast Yarrowia lipolytica for biofuel production
- (2012) Mitchell Tai et al. METABOLIC ENGINEERING
- Yarrowia lipolytica
- (2012) Jean-Marc Nicaud YEAST
- Tuning Gene Expression in Yarrowia lipolytica by a Hybrid Promoter Approach
- (2011) John Blazeck et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Improved enzyme production by bio-pellets of Aspergillus niger: Targeted morphology engineering using titanate microparticles
- (2011) Habib Driouch et al. BIOTECHNOLOGY AND BIOENGINEERING
- From zero to hero—Design-based systems metabolic engineering of Corynebacterium glutamicum for l-lysine production
- (2011) Judith Becker et al. METABOLIC ENGINEERING
- Effect of Plant Oils upon Lipase and Citric Acid Production inYarrowia lipolyticaYeast
- (2010) Farshad Darvishi et al. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY
- Detection and analysis of alternative splicing in Yarrowia lipolytica reveal structural constraints facilitating nonsense-mediated decay of intron-retaining transcripts
- (2010) Meryem Mekouar et al. GENOME BIOLOGY
- The gene balance hypothesis: implications for gene regulation, quantitative traits and evolution
- (2009) James A. Birchler et al. NEW PHYTOLOGIST
- Yarrowia lipolytica as a model for bio-oil production
- (2009) Athanasios Beopoulos et al. PROGRESS IN LIPID RESEARCH
- The effects of omega-3 fatty acids monotherapy in Alzheimer's disease and mild cognitive impairment: A preliminary randomized double-blind placebo-controlled study
- (2008) Chih-Chiang Chiu et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
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