Systems metabolic engineering upgrades Corynebacterium glutamicum for selective high-level production of the chiral drug precursor and cell-protective extremolyte L-pipecolic acid
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Systems metabolic engineering upgrades Corynebacterium glutamicum for selective high-level production of the chiral drug precursor and cell-protective extremolyte L-pipecolic acid
Authors
Keywords
-
Journal
METABOLIC ENGINEERING
Volume 77, Issue -, Pages 100-117
Publisher
Elsevier BV
Online
2023-03-16
DOI
10.1016/j.ymben.2023.03.006
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- High-efficiency production of the antimicrobial peptide pediocin PA-1 in metabolically engineered Corynebacterium glutamicum using a microaerobic process at acidic pH and elevated levels of bivalent calcium ions
- (2023) Jens Christmann et al. Microbial Cell Factories
- Enhancement of l-Pipecolic Acid Production by Dynamic Control of Substrates and Multiple Copies of the pipA Gene in the Escherichia coli Genome
- (2022) Xin Xu et al. ACS Synthetic Biology
- Biobased PET from lignin using an engineered cis, cis-muconate-producing Pseudomonas putida strain with superior robustness, energy and redox properties
- (2022) Michael Kohlstedt et al. METABOLIC ENGINEERING
- Systems metabolic engineering of Corynebacterium glutamicum eliminates all by-products for selective and high-yield production of the platform chemical 5-aminovalerate
- (2022) Christina Rohles et al. METABOLIC ENGINEERING
- Systems metabolic engineering upgrades Corynebacterium glutamicum to high-efficiency cis, cis-muconic acid production from lignin-based aromatics
- (2022) Fabia Weiland et al. METABOLIC ENGINEERING
- Advances in metabolic engineering of Corynebacterium glutamicum to produce high-value active ingredients for food, feed, human health, and well-being
- (2021) Sabrina Wolf et al. Essays in Biochemistry
- Cascaded valorization of brown seaweed to produce l-lysine and value-added products using Corynebacterium glutamicum streamlined by systems metabolic engineering
- (2021) Sarah Lisa Hoffmann et al. METABOLIC ENGINEERING
- Enhanced production of neoagarobiose from agar with Corynebacterium glutamicum producing exo‐type and endo‐type β‐agarases
- (2021) Eun Jung Jeon et al. Microbial Biotechnology
- Guiding stars to the field of dreams: Metabolically engineered pathways and microbial platforms for a sustainable lignin-based industry
- (2021) Fabia Weiland et al. METABOLIC ENGINEERING
- Enhancement of pipecolic acid production by the expression of multiple lysine cyclodeaminase in the Escherichia coli whole-cell system
- (2020) Yeong-Hoon Han et al. ENZYME AND MICROBIAL TECHNOLOGY
- Microparticles globally reprogram Streptomyces albus toward accelerated morphogenesis, streamlined carbon core metabolism, and enhanced production of the antituberculosis polyketide pamamycin
- (2020) Martin Kuhl et al. BIOTECHNOLOGY AND BIOENGINEERING
- Microbial production of extremolytes — high-value active ingredients for nutrition, health care, and well-being
- (2020) Judith Becker et al. CURRENT OPINION IN BIOTECHNOLOGY
- Function of L-Pipecolic Acid as Compatible Solute in Corynebacterium glutamicum as Basis for Its Production Under Hyperosmolar Conditions
- (2019) Fernando Pérez-García et al. Frontiers in Microbiology
- Modular systems metabolic engineering enables balancing of relevant pathways for l-histidine production with Corynebacterium glutamicum
- (2019) Andreas Schwentner et al. Biotechnology for Biofuels
- Metabolic engineering of Corynebacterium glutamicum for high‐level ectoine production – design, combinatorial assembly and implementation of a transcriptionally balanced heterologous ectoine pathway
- (2019) Gideon Gießelmann et al. Biotechnology Journal
- Continuous Adaptive Evolution of a Fast-Growing Corynebacterium glutamicum Strain Independent of Protocatechuate
- (2019) Michaela Graf et al. Frontiers in Microbiology
- Defence priming in Arabidopsis – a Meta-Analysis
- (2019) Sara M. Westman et al. Scientific Reports
- Model-based reconstruction of synthetic promoter library in Corynebacterium glutamicum
- (2018) Shuanghong Zhang et al. BIOTECHNOLOGY LETTERS
- Expanding lysine industry: industrial biomanufacturing of lysine and its derivatives
- (2018) Jie Cheng et al. JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
- An economically and environmentally acceptable synthesis of chiral drug intermediate l-pipecolic acid from biomass-derived lysine via artificially engineered microbes
- (2018) Jie Cheng et al. JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
- Improved riboflavin production with Ashbya gossypii from vegetable oil based on 13 C metabolic network analysis with combined labeling analysis by GC/MS, LC/MS, 1D, and 2D NMR
- (2018) Susanne Katharina Schwechheimer et al. METABOLIC ENGINEERING
- Lysine production from the sugar alcohol mannitol: Design of the cell factory Corynebacterium glutamicum SEA-3 through integrated analysis and engineering of metabolic pathway fluxes
- (2018) Sarah Lisa Hoffmann et al. METABOLIC ENGINEERING
- From lignin to nylon: Cascaded chemical and biochemical conversion using metabolically engineered Pseudomonas putida
- (2018) Michael Kohlstedt et al. METABOLIC ENGINEERING
- Metabolically engineered Corynebacterium glutamicum for bio-based production of chemicals, fuels, materials, and healthcare products
- (2018) Judith Becker et al. METABOLIC ENGINEERING
- Metabolic engineering of Corynebacterium glutamicum for the production of cis, cis-muconic acid from lignin
- (2018) Judith Becker et al. Microbial Cell Factories
- Pipecolic acid confers systemic immunity by regulating free radicals
- (2018) Caixia Wang et al. Science Advances
- A bio-based route to the carbon-5 chemical glutaric acid and to bionylon-6,5 using metabolically engineered Corynebacterium glutamicum
- (2018) Christina Maria Rohles et al. GREEN CHEMISTRY
- Corynebacterium Cell Factory Design and Culture Process Optimization for Muconic Acid Biosynthesis
- (2018) Han-Na Lee et al. Scientific Reports
- Bio-based succinate from sucrose: High-resolution 13 C metabolic flux analysis and metabolic engineering of the rumen bacterium Basfia succiniciproducens
- (2017) Anna Lange et al. METABOLIC ENGINEERING
- Fermentative production of L-pipecolic acid from glucose and alternative carbon sources
- (2017) Fernando Pérez-García et al. Biotechnology Journal
- Engineering Corynebacterium glutamicum for fast production of l-lysine and l-pipecolic acid
- (2016) Fernando Pérez-García et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Integrated analysis of gene expression and metabolic fluxes in PHA-producing Pseudomonas putida grown on glycerol
- (2016) Veronique Beckers et al. Microbial Cell Factories
- Systems metabolic engineering of Corynebacterium glutamicum for the production of the carbon-5 platform chemicals 5-aminovalerate and glutarate
- (2016) Christina Maria Rohles et al. Microbial Cell Factories
- Advanced Biotechnology: Metabolically Engineered Cells for the Bio-Based Production of Chemicals and Fuels, Materials, and Health-Care Products
- (2015) Judith Becker et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Priming for Enhanced Defense
- (2015) Uwe Conrath et al. Annual Review of Phytopathology
- Functional expression of l-lysine α-oxidase from Scomber japonicus in Escherichia coli for one-pot synthesis of l-pipecolic acid from dl-lysine
- (2014) Yasushi Tani et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Synthetic promoter libraries for Corynebacterium glutamicum
- (2014) Jakob Vang Rytter et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Adaptation ofBacillus subtiliscarbon core metabolism to simultaneous nutrient limitation and osmotic challenge: a multi-omics perspective
- (2014) Michael Kohlstedt et al. ENVIRONMENTAL MICROBIOLOGY
- Enhanced acetic acid and succinic acid production under microaerobic conditions by Corynebacterium glutamicum harboring Escherichia coli transhydrogenase gene pntAB
- (2014) Yuto Yamauchi et al. JOURNAL OF GENERAL AND APPLIED MICROBIOLOGY
- From zero to hero – Production of bio-based nylon from renewable resources using engineered Corynebacterium glutamicum
- (2014) Stefanie Kind et al. METABOLIC ENGINEERING
- Production of medium chain length polyhydroxyalkanoate in metabolic flux optimized Pseudomonas putida
- (2014) José Borrero-de Acuña et al. Microbial Cell Factories
- Isolation of fully synthetic promoters for high-level gene expression inCorynebacterium glutamicum
- (2013) Sung Sun Yim et al. BIOTECHNOLOGY AND BIOENGINEERING
- EngineeringEscherichia colifor renewable production of the 5-carbon polyamide building-blocks 5-aminovalerate and glutarate
- (2013) Jake Adkins et al. BIOTECHNOLOGY AND BIOENGINEERING
- Genome-wide analysis of lysine catabolism in bacteria reveals new connections with osmotic stress resistance
- (2013) Izabella AP Neshich et al. ISME Journal
- Systems metabolic engineering of Corynebacterium glutamicum for production of the chemical chaperone ectoine
- (2013) Judith Becker et al. Microbial Cell Factories
- Systems and synthetic metabolic engineering for amino acid production – the heartbeat of industrial strain development
- (2012) Judith Becker et al. CURRENT OPINION IN BIOTECHNOLOGY
- Metabolic Regulation, Mitochondria and the Life-Prolonging Effect of Rapamycin: A Mini-Review
- (2012) Yong Pan et al. GERONTOLOGY
- Increased lysine production by flux coupling of the tricarboxylic acid cycle and the lysine biosynthetic pathway—Metabolic engineering of the availability of succinyl-CoA in Corynebacterium glutamicum
- (2012) Stefanie Kind et al. METABOLIC ENGINEERING
- Metabolic engineering of Corynebacterium glutamicum for production of 1,5-diaminopentane from hemicellulose
- (2011) Nele Buschke et al. Biotechnology Journal
- Bio-based production of chemicals, materials and fuels – Corynebacterium glutamicum as versatile cell factory
- (2011) Judith Becker et al. CURRENT OPINION IN BIOTECHNOLOGY
- From zero to hero—Design-based systems metabolic engineering of Corynebacterium glutamicum for l-lysine production
- (2011) Judith Becker et al. METABOLIC ENGINEERING
- Metabolic engineering of cellular transport for overproduction of the platform chemical 1,5-diaminopentane in Corynebacterium glutamicum
- (2011) Stefanie Kind et al. METABOLIC ENGINEERING
- Engineering of Corynebacterium glutamicum with an NADPH-Generating Glycolytic Pathway for L-Lysine Production
- (2010) S. Takeno et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Systems level engineering of Corynebacterium glutamicum - Reprogramming translational efficiency for superior production
- (2010) Judith Becker et al. ENGINEERING IN LIFE SCIENCES
- Stereoselective Syntheses ofl-Pipecolic Acid and (2S,3S)-3-Hydroxypipecolic Acid from a ChiralN-Imino-2-phenyl-1,2-dihydropyridine Intermediate
- (2010) Alexandre Lemire et al. JOURNAL OF ORGANIC CHEMISTRY
- Systems-wide metabolic pathway engineering in Corynebacterium glutamicum for bio-based production of diaminopentane
- (2010) Stefanie Kind et al. METABOLIC ENGINEERING
- Metabolic Engineering of the Tricarboxylic Acid Cycle for Improved Lysine Production by Corynebacterium glutamicum
- (2009) J. Becker et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Functional genomics of pH homeostasis in Corynebacterium glutamicum revealed novel links between pH response, oxidative stress, iron homeostasis and methionine synthesis
- (2009) Martin Follmann et al. BMC GENOMICS
- Enzymatic assembly of DNA molecules up to several hundred kilobases
- (2009) Daniel G Gibson et al. NATURE METHODS
- Metabolic responses to pyruvate kinase deletion in lysine producing Corynebacterium glutamicum
- (2008) Judith Becker et al. Microbial Cell Factories
- Physiological response of Corynebacterium glutamicum to oxidative stress induced by deletion of the transcriptional repressor McbR
- (2008) J. O. Kromer et al. MICROBIOLOGY-SGM
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now