Recent research advances in metabolism, clinical and experimental

The global burden of metabolic disease: Data from 2000 to 2019

(2023) Nicholas W.S. Chew et al.   Cell Metabolism

The Association between Cardio-metabolic and hepatic indices and anthropometric measures with metabolically obesity phenotypes: a cross-sectional study from the Hoveyzeh Cohort Study

(2023) Mehrnoosh Zakerkish et al.   BMC Endocrine Disorders

Pharmacotherapy of obesity: an update on the available medications and drugs under investigation

(2023) Marlene Chakhtoura et al.   EClinicalMedicine

Addendum. 3. Prevention or Delay of Type 2 Diabetes and Associated Comorbidities: Standards of Care in Diabetes—2023. Diabetes Care 2023;46(Suppl. 1):S41–S48

(2023) Nuha A. ElSayed et al.   DIABETES CARE

Dietary patterns, socioeconomic disparities, and risk of type 2 diabetes in the Sister Study

(2023) Brittany Crawford et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

From non-alcoholic fatty liver disease (NAFLD) to steatotic liver disease (SLD): an ongoing journey towards refining the terminology for this prevalent metabolic condition and unmet clinical need

(2023) Michail Kokkorakis et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Milestones in the journey towards addressing obesity; Past trials and triumphs, recent breakthroughs, and an exciting future in the era of emerging effective medical therapies and integration of effective medical therapies with metabolic surgery

(2023) Michail Kokkorakis et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Obesity and infectious diseases: pathophysiology and epidemiology of a double pandemic condition

(2022) Gabriella Pugliese et al.   INTERNATIONAL JOURNAL OF OBESITY

Pandemic preparedness and COVID-19: an exploratory analysis of infection and fatality rates, and contextual factors associated with preparedness in 177 countries, from Jan 1, 2020, to Sept 30, 2021

(2022) Thomas J Bollyky et al.   LANCET

Deacetylation of Caveolin-1 by Sirt6 induces autophagy and retards high glucose-stimulated LDL transcytosis and atherosclerosis formation

(2022) Ying Zhao et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Dietary carbohydrate and the risk of type 2 diabetes: an updated systematic review and dose–response meta-analysis of prospective cohort studies

(2022) Fatemeh Hosseini et al.   Scientific Reports

A 2022 update on the epidemiology of obesity and a call to action: as its twin COVID-19 pandemic appears to be receding, the obesity and dysmetabolism pandemic continues to rage on

(2022) Chrysoula Boutari et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Editorial: Obesity, metabolic phenotypes and COVID-19

(2022) Despina Sanoudou et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Preadmission use of antidiabetic medications and mortality among patients with COVID-19 having type 2 diabetes: A meta-analysis

(2022) Nam Nhat Nguyen et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Machine learning and semi-targeted lipidomics identify distinct serum lipid signatures in hospitalized COVID-19-positive and COVID-19-negative patients

(2022) Helena Castañé et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Schisandrin B mitigates hepatic steatosis and promotes fatty acid oxidation by inducing autophagy through AMPK/mTOR signaling pathway

(2022) Li-Shan Yan et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Metabolic dysfunction-associated fatty liver disease predicts new onset of chronic kidney disease better than does fatty liver or nonalcoholic fatty liver disease

(2022) Marenao Tanaka et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Higd1a facilitates exercise-mediated alleviation of fatty liver in diet-induced obese mice

(2022) Jie-Ying Zhu et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Metabolic dysfunction-associated fatty liver disease and implications for cardiovascular risk and disease prevention

(2022) Xiao-Dong Zhou et al.   Cardiovascular Diabetology

The functional role of Higd1a in mitochondrial homeostasis and in multiple disease processes

(2022) Jie-Ying Zhu et al.   Genes and Diseases

Nonalcoholic Fatty Pancreas Disease: Role in Metabolic Syndrome, “Prediabetes,” Diabetes and Atherosclerosis

(2021) T. D. Filippatos et al.   DIGESTIVE DISEASES AND SCIENCES

Cancer Risk in Patients With Biopsy‐Confirmed Nonalcoholic Fatty Liver Disease: A Population‐Based Cohort Study

(2021) Tracey G. Simon et al.   HEPATOLOGY

Non-alcoholic fatty liver disease

(2021) Elizabeth E Powell et al.   LANCET

Impact of body composition on COVID-19 susceptibility and severity: A two-sample multivariable Mendelian randomization study

(2021) Dennis Freuer et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Prescription of glucose-lowering therapies and risk of COVID-19 mortality in people with type 2 diabetes: a nationwide observational study in England

(2021) Kamlesh Khunti et al.   Lancet Diabetes & Endocrinology

Metabolically Healthy Obesity Redefined

(2021) Ayana K. April-Sanders et al.   JAMA Network Open

Lipids activate skeletal muscle mitochondrial fission and quality control networks to induce insulin resistance in humans

(2021) Christopher L. Axelrod et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Incretin-based therapies in 2021 – Current status and perspectives for the future

(2021) Manfredi Rizzo et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

FOS/GOS attenuates high-fat diet induced bone loss via reversing microbiota dysbiosis, high intestinal permeability and systemic inflammation in mice

(2021) Zheng Zhang et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Preparing for the NASH epidemic: A call to action

(2021) Fasiha Kanwal et al.   Obesity

COVID-19–Induced New-Onset Diabetes: Trends and Technologies

(2021) Ahmed A. Metwally et al.   DIABETES

C C chemokine ligand 3 deficiency ameliorates diet-induced steatohepatitis by regulating liver macrophage recruitment and M1/M2 status in mice

(2021) Liang Xu et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Diet and exercise reduce pre-existing NASH and fibrosis and have additional beneficial effects on the vasculature, adipose tissue and skeletal muscle via organ-crosstalk

(2021) Anita M. van den Hoek et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Metabolically Healthy Obesity

(2020) Matthias Blüher   ENDOCRINE REVIEWS

Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study

(2020) Nanshan Chen et al.   LANCET

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

(2020) Chaolin Huang et al.   LANCET

Carbohydrate Quality, Glycemic Index, Glycemic Load and Cardiometabolic Risks in the US, Europe and Asia: A Dose-Response Meta-Analysis

(2020) D.S. Hardy et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Epidemiology and pathophysiology of the association between NAFLD and metabolically healthy or metabolically unhealthy obesity

(2020) Amedeo Lonardo et al.   Annals of Hepatology

Obesity a Risk Factor for Severe COVID-19 Infection: Multiple Potential Mechanisms

(2020) Naveed Sattar et al.   CIRCULATION

COVID-19 and African Americans

(2020) Clyde W. Yancy   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Lipid Accumulation in Hearts Transplanted From Nondiabetic Donors to Diabetic Recipients

(2020) Raffaele Marfella et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

High prevalence of obesity in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) requiring invasive mechanical ventilation

(2020) Arthur Simonnet et al.   Obesity

Prevalence of obesity among adult inpatients with COVID-19 in France

(2020) Cyrielle Caussy et al.   Lancet Diabetes & Endocrinology

Global prevalence, incidence, and outcomes of non-obese or lean non-alcoholic fatty liver disease: a systematic review and meta-analysis

(2020) Qing Ye et al.   Lancet Gastroenterology & Hepatology

NAFLD and cardiovascular diseases: a clinical review

(2020) Philipp Kasper et al.   Clinical Research in Cardiology

The role of Peroxisome Proliferator-Activated Receptors (PPAR) in immune responses

(2020) Anthos Christofides et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Visceral fat shows the strongest association with the need of intensive Care in Patients with COVID-19

(2020) Mikiko Watanabe et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

NAFLD as a continuum: from obesity to metabolic syndrome and diabetes

(2020) Amélio F. Godoy-Matos et al.   Diabetology & Metabolic Syndrome

Hyperglycemia Induces Myocardial Dysfunction via Epigenetic Regulation of JunD

(2020) Shafaat Hussain et al.   CIRCULATION RESEARCH

Profibrotic Circulating Proteins and Risk of Early Progressive Renal Decline in Patients With Type 2 Diabetes With and Without Albuminuria

(2020) Katsuhito Ihara et al.   DIABETES CARE

The role of visceral adiposity in the severity of COVID-19: Highlights from a unicenter cross-sectional pilot study in Germany

(2020) Antonia Petersen et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Immunological mechanisms and therapeutic targets of fatty liver diseases

(2020) Hua Wang et al.   Cellular & Molecular Immunology

Intake of dietary fats and fatty acids and the incidence of type 2 diabetes: A systematic review and dose-response meta-analysis of prospective observational studies

(2020) Manuela Neuenschwander et al.   PLOS MEDICINE

A signature of circulating inflammatory proteins and development of end-stage renal disease in diabetes

(2019) Monika A. Niewczas et al.   NATURE MEDICINE

Maternal Exposure to High Fructose and Offspring Health

(2019) Guanghong Jia et al.   HYPERTENSION

The Global Epidemiology of NAFLD and NASH in Patients with type 2 diabetes: A Systematic Review and Meta-analysis

(2019) Zobair M. Younossi et al.   JOURNAL OF HEPATOLOGY

CAV1-CAVIN1-LC3B-mediated autophagy regulates high glucose-stimulated LDL transcytosis

(2019) Xiangli Bai et al.   Autophagy

Association of epicardial adipose tissue with non-alcoholic fatty liver disease: a meta-analysis

(2019) Bin Liu et al.   Hepatology International

Molecular mechanisms of hepatic lipid accumulation in non-alcoholic fatty liver disease

(2018) David Højland Ipsen et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

A randomized, placebo-controlled trial of cenicriviroc for treatment of nonalcoholic steatohepatitis with fibrosis

(2018) Scott L. Friedman et al.   HEPATOLOGY

Epithelial Sodium Channel in Aldosterone-Induced Endothelium Stiffness and Aortic Dysfunction

(2018) Guanghong Jia et al.   HYPERTENSION

NHLBI Working Group Recommendations to Reduce Lipoprotein(a)-Mediated Risk of Cardiovascular Disease and Aortic Stenosis

(2018) Sotirios Tsimikas et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Markers of early progressive renal decline in type 2 diabetes suggest different implications for etiological studies and prognostic tests development

(2018) Natalia Nowak et al.   KIDNEY INTERNATIONAL

Apoptosis and non-alcoholic fatty liver diseases

(2018) Tatsuo Kanda et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Obesity-induced activation of JunD promotes myocardial lipid accumulation and metabolic cardiomyopathy

(2018) Sarah Costantino et al.   EUROPEAN HEART JOURNAL

Gut microbiota dysbiosis in patients with non-alcoholic fatty liver disease

(2017) Feng Shen et al.   Hepatobiliary & Pancreatic Diseases International

Metabolism disrupting chemicals and metabolic disorders

(2017) Jerrold J. Heindel et al.   REPRODUCTIVE TOXICOLOGY

Cavin-1 regulates caveolae-mediated LDL transcytosis: crosstalk in an AMPK/eNOS/ NF-κB/Sp1 loop

(2017) Xiang-Li Bai et al.   Oncotarget

Gut microbiota dysbiosis associated with glucose metabolism disorders and the metabolic syndrome in older adults

(2017) K. Lippert et al.   Beneficial Microbes

Podocyte Activation of NLRP3 Inflammasomes Contributes to the Development of Proteinuria in Lupus Nephritis

(2017) Rong Fu et al.   Arthritis & Rheumatology

Endothelial Mineralocorticoid Receptor Mediates Diet-Induced Aortic Stiffness in FemalesNovelty and Significance

(2016) Guanghong Jia et al.   CIRCULATION RESEARCH

Non-alcoholic fatty liver disease and risk of incident cardiovascular disease: A meta-analysis

(2016) Giovanni Targher et al.   JOURNAL OF HEPATOLOGY

Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-based studies with 4·4 million participants

(2016)   LANCET

Dynamics of protein secretion during adipocyte differentiation

(2016) Koichi Ojima et al.   FEBS Open Bio

Lipoprotein (a) as a risk factor for ischemic stroke: A meta-analysis

(2015) Alexander H. Nave et al.   ATHEROSCLEROSIS

Weight Loss Through Lifestyle Modification Significantly Reduces Features of Nonalcoholic Steatohepatitis

(2015) Eduardo Vilar-Gomez et al.   GASTROENTEROLOGY

The expanded collagen VI family: new chains and new questions

(2013) Jamie Fitzgerald et al.   CONNECTIVE TISSUE RESEARCH

Hyperglycemia-induced Oxidative Stress and its Role in Diabetes Mellitus Related Cardiovascular Diseases

(2013) Teresa Fiorentino et al.   CURRENT PHARMACEUTICAL DESIGN

Obesity and Insulin Resistance Induce Early Development of Diastolic Dysfunction in Young Female Mice Fed a Western Diet

(2013) Camila Manrique et al.   ENDOCRINOLOGY

Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice

(2013) V. K. Ridaura et al.   SCIENCE

The proteomic signature of insulin-resistant human skeletal muscle reveals increased glycolytic and decreased mitochondrial enzymes

(2012) J. Giebelstein et al.   DIABETOLOGIA

A framework for human microbiome research

(2012)   NATURE

Arterial Stiffness is Strongly Associated with Insulin Resistance in Chinese —A Population-Based Study (Taichung Community Health Study, TCHS)

(2011) Chih-Te Ho et al.   Journal of Atherosclerosis and Thrombosis

Inhibitory effect of schisandrin B on free fatty acid-induced steatosis in L-02 cells

(2011) Jian-Hong Chu   WORLD JOURNAL OF GASTROENTEROLOGY

Evolution of inflammation in nonalcoholic fatty liver disease: The multiple parallel hits hypothesis

(2010) Herbert Tilg et al.   HEPATOLOGY

Safety and efficacy of long-term statin treatment for cardiovascular events in patients with coronary heart disease and abnormal liver tests in the Greek Atorvastatin and Coronary Heart Disease Evaluation (GREACE) Study: a post-hoc analysis

(2010) Vasilios G Athyros et al.   LANCET