Lactate’s behavioral switch in the brain: An in-silico model

Astrocytes as Key Regulators of Brain Energy Metabolism: New Therapeutic Perspectives

(2022) Elidie Beard et al.   Frontiers in Physiology

The potential mechanisms of lactate in mediating exercise-enhanced cognitive function: a dual role as an energy supply substrate and a signaling molecule

(2022) Xiangli Xue et al.   Nutrition & Metabolism

Lactate as Potential Mediators for Exercise-Induced Positive Effects on Neuroplasticity and Cerebrovascular Plasticity

(2021) Zhihai Huang et al.   Frontiers in Physiology

Universal Glia to Neurone Lactate Transfer in the Nervous System: Physiological Functions and Pathological Consequences

(2020) Carolyn L. Powell et al.   Biosensors-Basel

Glycolysis-Derived Compounds From Astrocytes That Modulate Synaptic Communication

(2019) Carlos-Alberto Gonçalves et al.   Frontiers in Neuroscience

Mathematical Modeling of Substrates Fluxes and Tumor Growth in the Brain

(2019) Angélique Perrillat-Mercerot et al.   ACTA BIOTHEORETICA

Brain energetics plays a key role in the coordination of electrophysiology, metabolism and hemodynamics: Evidence from an integrated computational model

(2019) G. Capo Rangel et al.   JOURNAL OF THEORETICAL BIOLOGY

Computational singular perturbation analysis of brain lactate metabolism

(2019) Dimitris G. Patsatzis et al.   PLoS One

The Science and Translation of Lactate Shuttle Theory

(2018) George A. Brooks   Cell Metabolism

Lactate in the brain: from metabolic end-product to signalling molecule

(2018) Pierre J. Magistretti et al.   NATURE REVIEWS NEUROSCIENCE

Non-Canonical Control of Neuronal Energy Status by the Na+ Pump

(2018) Felipe Baeza-Lehnert et al.   Cell Metabolism

Glycolysis Paradigm Shift Dictates a Reevaluation of Glucose and Oxygen Metabolic Rates of Activated Neural Tissue

(2018) Avital Schurr   Frontiers in Neuroscience

Mathematical analysis of the influence of brain metabolism on the BOLD signal in Alzheimer’s disease

(2017) Felix Winter et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Arterialized and venous blood lactate concentration difference during different exercise intensities

(2017) Leandro C. Felippe et al.   Journal of Exercise Science & Fitness

Astrocytic glycogen-derived lactate fuels the brain during exhaustive exercise to maintain endurance capacity

(2017) Takashi Matsui et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of Systemic Metabolic Fuels on Glucose and Lactate Levels in the Brain Extracellular Compartment of the Mouse

(2017) Alexandria Béland-Millar et al.   Frontiers in Neuroscience

Lactate Shuttles in Neuroenergetics—Homeostasis, Allostasis and Beyond

(2017) Shayne Mason   Frontiers in Neuroscience

In Vivo Evidence for a Lactate Gradient from Astrocytes to Neurons

(2016) Philipp Mächler et al.   Cell Metabolism

Regulation of neurovascular coupling in autoimmunity to water and ion channels

(2015) Peter Jukkola et al.   AUTOIMMUNITY REVIEWS

Channel-Mediated Lactate Release by K+-Stimulated Astrocytes

(2015) T. Sotelo-Hitschfeld et al.   JOURNAL OF NEUROSCIENCE

The lactate receptor, G-protein-coupled receptor 81/hydroxycarboxylic acid receptor 1: Expression and action in brain

(2015) Cecilie Morland et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Lactate: Brain Fuel in Human Traumatic Brain Injury: A Comparison with Normal Healthy Control Subjects

(2015) Thomas C. Glenn et al.   JOURNAL OF NEUROTRAUMA

Multi-timescale Modeling of Activity-Dependent Metabolic Coupling in the Neuron-Glia-Vasculature Ensemble

(2015) Renaud Jolivet et al.   PLoS Computational Biology

Role of Monocarboxylate Transporters in Drug Delivery to the Brain

(2014) Nisha Vijay et al.   CURRENT PHARMACEUTICAL DESIGN

Lactate Transport and Signaling in the Brain: Potential Therapeutic Targets and Roles in Body—Brain Interaction

(2014) Linda Hildegard Bergersen   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Energy metabolism and glutamate-glutamine cycle in the brain: a stoichiometric modeling perspective

(2013) Francesco A Massucci et al.   BMC Systems Biology

Monocarboxylate transporters in temporal lobe epilepsy: roles of lactate and ketogenic diet

(2013) Fredrik Lauritzen et al.   Brain Structure & Function

Etiology and Therapeutic Approach to Elevated Lactate Levels

(2013) Lars W. Andersen et al.   MAYO CLINIC PROCEEDINGS

The Metabolism of Neurons and Astrocytes Through Mathematical Models

(2012) E. Somersalo et al.   ANNALS OF BIOMEDICAL ENGINEERING

Determinants of Brain Cell Metabolic Phenotypes and Energy Substrate Utilization Unraveled with a Modeling Approach

(2012) Aitana Neves et al.   PLoS Computational Biology

Astrocyte - neuron lactate shuttle may boost more ATP supply to the neuron under hypoxic conditions - in silico study supported by in vitro expression data

(2011) Seda Genc et al.   BMC Systems Biology

Brain Energy Metabolism: Focus on Astrocyte-Neuron Metabolic Cooperation

(2011) Mireille Bélanger et al.   Cell Metabolism

Cerebral glucose and lactate consumption during cerebral activation by physical activity in humans

(2011) Peter Rasmussen et al.   FASEB JOURNAL

Sweet Sixteen for ANLS

(2011) Luc Pellerin et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Comment on Recent Modeling Studies of Astrocyte–Neuron Metabolic Interactions

(2010) Renaud Jolivet et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The Contribution of Blood Lactate to Brain Energy Metabolism in Humans Measured by Dynamic 13C Nuclear Magnetic Resonance Spectroscopy

(2010) F. Boumezbeur et al.   JOURNAL OF NEUROSCIENCE

Glucose and lactate supply to the synapse

(2009) L. Felipe Barros et al.   BRAIN RESEARCH REVIEWS

Changes in Glucose Uptake Rather than Lactate Shuttle Take Center Stage in Subserving Neuroenergetics: Evidence from Mathematical Modeling

(2009) Mauro DiNuzzo et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

An integrative dynamic model of brain energy metabolism using in vivo neurochemical measurements

(2009) Mathieu Cloutier et al.   JOURNAL OF COMPUTATIONAL NEUROSCIENCE

Astrocytes are poised for lactate trafficking and release from activated brain and for supply of glucose to neurons

(2009) Gautam K. Gandhi et al.   JOURNAL OF NEUROCHEMISTRY

Lactate fuels the human brain during exercise

(2008) Bjørn Quistorff et al.   FASEB JOURNAL

Astrocytes as the Glucose Shunt for Glutamatergic Neurons at High Activity: An In Silico Study

(2008) Rossana Occhipinti et al.   JOURNAL OF NEUROPHYSIOLOGY

Evidence for the Mitochondrial Lactate Oxidation Complex in Rat Neurons: Demonstration of an Essential Component of Brain Lactate Shuttles

(2008) Takeshi Hashimoto et al.   PLoS One