Multi-timescale Modeling of Activity-Dependent Metabolic Coupling in the Neuron-Glia-Vasculature Ensemble

Capillary pericytes regulate cerebral blood flow in health and disease

(2014) Catherine N. Hall et al.   NATURE

Lactate promotes plasticity gene expression by potentiating NMDA signaling in neurons

(2014) J. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lactate Receptor Sites Link Neurotransmission, Neurovascular Coupling, and Brain Energy Metabolism

(2013) K. H. Lauritzen et al.   CEREBRAL CORTEX

Early impairment in brain metabolism detected by MR spectroscopy antedates structural changes in mouse models of spinocerebellar ataxias

(2013) Vladimír Mlynárik et al.   JOURNAL OF NEUROCHEMISTRY

Sleep Drives Metabolite Clearance from the Adult Brain

(2013) L. Xie et al.   SCIENCE

Multimodal Imaging in Rats Reveals Impaired Neurovascular Coupling in Sustained Hypertension

(2013) Novella Calcinaghi et al.   STROKE

Metabolic signaling by lactate in the brain

(2013) L. Felipe Barros   TRENDS IN NEUROSCIENCES

An inverse-Warburg effect and the origin of Alzheimer’s disease

(2012) Lloyd A. Demetrius et al.   BIOGERONTOLOGY

Synaptic Energy Use and Supply

(2012) Julia J. Harris et al.   NEURON

Determinants of Brain Cell Metabolic Phenotypes and Energy Substrate Utilization Unraveled with a Modeling Approach

(2012) Aitana Neves et al.   PLoS Computational Biology

Astrocyte - neuron lactate shuttle may boost more ATP supply to the neuron under hypoxic conditions - in silico study supported by in vitro expression data

(2011) Seda Genc et al.   BMC Systems Biology

Astrocyte-Neuron Lactate Transport Is Required for Long-Term Memory Formation

(2011) Akinobu Suzuki et al.   CELL

Metabotropic glutamate receptor mGluR5 is not involved in the early hemodynamic response

(2011) Novella Calcinaghi et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Sweet Sixteen for ANLS

(2011) Luc Pellerin et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Modeling the contribution of neuron-astrocyte cross talk to slow blood oxygenation level-dependent signal oscillations

(2011) Mauro DiNuzzo et al.   JOURNAL OF NEUROPHYSIOLOGY

NBCe1 Mediates the Acute Stimulation of Astrocytic Glycolysis by Extracellular K+

(2011) I. Ruminot et al.   JOURNAL OF NEUROSCIENCE

In Vivo Evidence for Lactate as a Neuronal Energy Source

(2011) M. T. Wyss et al.   JOURNAL OF NEUROSCIENCE

Lactate Produced by Glycogenolysis in Astrocytes Regulates Memory Processing

(2011) Lori A. Newman et al.   PLoS One

Comment on Recent Modeling Studies of Astrocyte–Neuron Metabolic Interactions

(2010) Renaud Jolivet et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Predominant Enhancement of Glucose Uptake in Astrocytes versus Neurons during Activation of the Somatosensory Cortex

(2010) J. Chuquet et al.   JOURNAL OF NEUROSCIENCE

Glial and neuronal control of brain blood flow

(2010) David Attwell et al.   NATURE

Changes in Glucose Uptake Rather than Lactate Shuttle Take Center Stage in Subserving Neuroenergetics: Evidence from Mathematical Modeling

(2009) Mauro DiNuzzo et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Neuroprotective Role of Lactate after Cerebral Ischemia

(2009) Carole Berthet et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

An integrative dynamic model of brain energy metabolism using in vivo neurochemical measurements

(2009) Mathieu Cloutier et al.   JOURNAL OF COMPUTATIONAL NEUROSCIENCE

Thein vivoneuron-to-astrocyte lactate shuttle in human brain: evidence from modeling of measured lactate levels during visual stimulation

(2009) Silvia Mangia et al.   JOURNAL OF NEUROCHEMISTRY

The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C–Cdh1

(2009) Angel Herrero-Mendez et al.   NATURE CELL BIOLOGY

Brain metabolism dictates the polarity of astrocyte control over arterioles

(2008) Grant R. J. Gordon et al.   NATURE