Universal Glia to Neurone Lactate Transfer in the Nervous System: Physiological Functions and Pathological Consequences

Stress gates an astrocytic energy reservoir to impair synaptic plasticity

(2020) Ciaran Murphy-Royal et al.   Nature Communications

Disrupted function of lactate transporter MCT1 , but not MCT4 , in Schwann cells affects the maintenance of motor end‐plate innervation

(2020) Filipa Bouçanova et al.   GLIA

Neuronal and astroglial monocarboxylate transporters play key but distinct roles in hippocampus-dependent learning and memory formation

(2020) Citlalli Netzahualcoyotzi et al.   PROGRESS IN NEUROBIOLOGY

Glial Metabolic Rewiring Promotes Axon Regeneration and Functional Recovery in the Central Nervous System

(2020) Feng Li et al.   Cell Metabolism

A glycolytic shift in Schwann cells supports injured axons

(2020) Elisabetta Babetto et al.   NATURE NEUROSCIENCE

Monocarboxylate transporter 1 in Schwann cells contributes to maintenance of sensory nerve myelination during aging

(2019) Mithilesh Kumar Jha et al.   GLIA

Ultrastructural Evidence for a Role of Astrocytes and Glycogen-Derived Lactate in Learning-Dependent Synaptic Stabilization

(2019) E Vezzoli et al.   CEREBRAL CORTEX

Energy metabolism in ALS: an underappreciated opportunity?

(2018) Tijs Vandoorne et al.   ACTA NEUROPATHOLOGICA

Inadequate brain glycogen or sleep increases spreading depression susceptibility

(2018) Kivilcim Kilic et al.   ANNALS OF NEUROLOGY

Lactate, not Lactic Acid, is Produced by Cellular Cytosolic Energy Catabolism

(2018) Robert A. Robergs et al.   PHYSIOLOGY

DISC1 regulates lactate metabolism in astrocytes: implications for psychiatric disorders

(2018) Yan Jouroukhin et al.   Translational Psychiatry

Lactate Deficit in an Alzheimer Disease Mouse Model: The Relationship With Neuronal Damage

(2018) Mao Zhang et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Glucocorticoid receptor signaling in astrocytes is required for aversive memory formation

(2018) Magdalena Tertil et al.   Translational Psychiatry

Tight coupling of astrocyte energy metabolism to synaptic activity revealed by genetically encoded FRET nanosensors in hippocampal tissue

(2017) Iván Ruminot et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Astrocytic l -Lactate Signaling Facilitates Amygdala-Anterior Cingulate Cortex Synchrony and Decision Making in Rats

(2017) Jun Wang et al.   Cell Reports

In Vivo Evidence for a Lactate Gradient from Astrocytes to Neurons

(2016) Philipp Mächler et al.   Cell Metabolism

Cerebrospinal fluid lactate levels and brain [18F]FDG PET hypometabolism within the default mode network in Alzheimer’s disease

(2016) Claudio Liguori et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Increased pregenual anterior cingulate glucose and lactate concentrations in major depressive disorder

(2016) J Ernst et al.   MOLECULAR PSYCHIATRY

Peripheral administration of lactate produces antidepressant-like effects

(2016) A Carrard et al.   MOLECULAR PSYCHIATRY

Deficiency in monocarboxylate transporter 1 (MCT1) in mice delays regeneration of peripheral nerves following sciatic nerve crush

(2015) Brett M. Morrison et al.   EXPERIMENTAL NEUROLOGY

Channel-Mediated Lactate Release by K+-Stimulated Astrocytes

(2015) T. Sotelo-Hitschfeld et al.   JOURNAL OF NEUROSCIENCE

Changes in lactate content and monocarboxylate transporter 2 expression in Aβ25-35-treated rat model of Alzheimer’s disease

(2015) Weitian Lu et al.   NEUROLOGICAL SCIENCES

Brain glucose metabolism in an animal model of depression

(2015) J. Detka et al.   NEUROSCIENCE

Lactate promotes plasticity gene expression by potentiating NMDA signaling in neurons

(2014) J. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Cajal school and the physiological role of astrocytes: a way of thinking

(2014) Marta Navarrete   Frontiers in Neuroanatomy

Novel hypoglycemic injury mechanism: N-methyl-D-aspartate receptor-mediated white matter damage

(2013) Xin Yang et al.   ANNALS OF NEUROLOGY

Lactate kinetics at the lactate threshold in trained and untrained men

(2013) Laurent A. Messonnier et al.   JOURNAL OF APPLIED PHYSIOLOGY

A Genetically Encoded FRET Lactate Sensor and Its Use To Detect the Warburg Effect in Single Cancer Cells

(2013) Alejandro San Martín et al.   PLoS One

Early Decline in Glucose Transport and Metabolism Precedes Shift to Ketogenic System in Female Aging and Alzheimer's Mouse Brain: Implication for Bioenergetic Intervention

(2013) Fan Ding et al.   PLoS One

Small is fast: astrocytic glucose and lactate metabolism at cellular resolution

(2013) L. F. Barros et al.   Frontiers in Cellular Neuroscience

Schwann cell glycogen selectively supports myelinated axon function

(2012) Angus M. Brown et al.   ANNALS OF NEUROLOGY

Dysregulation of astrocyte–motoneuron cross-talk in mutant superoxide dismutase 1-related amyotrophic lateral sclerosis

(2011) Laura Ferraiuolo et al.   BRAIN

Astrocyte-Neuron Lactate Transport Is Required for Long-Term Memory Formation

(2011) Akinobu Suzuki et al.   CELL

The monocarboxylate transporter family-Structure and functional characterization

(2011) Andrew P. Halestrap   IUBMB LIFE

Glycogenolysis in Astrocytes Supports Blood-Borne Glucose Channeling Not Glycogen-Derived Lactate Shuttling to Neurons: Evidence from Mathematical Modeling

(2010) Mauro DiNuzzo et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Spatial correlation between brain aerobic glycolysis and amyloid-β (Aβ) deposition

(2010) Andrei G. Vlassenko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization of 1,4-dideoxy-1,4-imino-d-arabinitol (DAB) as an inhibitor of brain glycogen shunt activity

(2008) Anne B. Walls et al.   JOURNAL OF NEUROCHEMISTRY

Brain metabolism dictates the polarity of astrocyte control over arterioles

(2008) Grant R. J. Gordon et al.   NATURE

The energy hypothesis of sleep revisited

(2008) Matthew T. Scharf et al.   PROGRESS IN NEUROBIOLOGY